Is surgery superior for distal ulna fractures? a comprehensive systematic review and meta-analysis by Zakaria Chabihi, Brahim Demnati, Mohamed Moussadiq, Tariq Aalil, Yassine Fath El Khir, El Mehdi Boumediane, Mohamed Amine Benhima, Imad Abkari

“…However, a higher union rate was observed with surgical management. Limitations The moderate quality of the included studies and the moderate to high heterogeneity among them are noted as limitations, indicating a need for more standardized research methodologies in this area. …”
Get full text

Effects of movement behaviors on preschoolers’ cognition: a systematic review of randomized controlled trials by Catalina Pacheco, Victoria Culkin, Amelia Putkaradze, Nan Zeng

“…Conclusions Cognitively engaging PA interventions demonstrated the largest effects, while motor skill-focused and general PA programs produced moderate to smaller gains. Evidence on SB and sleep interventions remains limited, with no studies exploring the combined effects of these three movement behaviors. …”
Get full text

Correlation of clinically significant prostate cancer sites across multiparametric MRI, prostate biopsy, and whole-mount pathology for optimal prostate biopsy strategy by Matteo Pacini, Alessandro Zucchi, Riccardo Morganti, Filippo Dazzi, Antonio Luigi Pastore, Fabio Maria Valenzi, Andrea Fuschi, Yazan al Salhi, Gianluca Giannarini, Vincenzo Ficarra, Alchiede Simonato, Petar Antonov, Pinuccia Faviana, Riccardo Bartoletti

“…The correlation between mpMRI, PB, and WMA was moderate and comparable in both groups. No correlation between PB and WMA was found in the TB group for PI-RADS3 lesions, while a moderate-strong correlation was observed when comparing mpMRI, PB, and WMA for PI-RADS > 3 lesions. …”
Get full text

Changes in climate extreme indices and agricultural drought monitoring in the semi-arid areas of Borana zone, southern Ethiopia by Girma Asefa Bogale, Asfaw Kebede Kassa, Mengistu Mengesha Maja

“…However, standardized precipitation indices of R10, R20, R95p, and R99p indicated moderate drought across the studied districts of Borana zone. …”
Get full text

Factors, characteristics and influences of the changes of muscle activation patterns for patients with knee osteoarthritis: a review by Shizhong Liu, Zuyu Du, Le Song, Haoyue Liu, Clarence Augustine T. H. Tee, Huanyu Liu, Yuan Liu

“…Conclusion In patients with moderate KOA, changes in MAP are mainly related to symptoms and the difficulty of tasks. …”
Get full text

Profiles and predictors of access to human and veterinary healthcare in multispecies households by Jennifer W. Applebaum, Courtney Dunn, Shelby E. McDonald, Kaylinn Escobar, Erin K. King, Rosalie Corona, Megan K. Mueller

“…The fourth subgroup, “Moderate access” (11%), characterized by financial barriers despite non-employer health insurance, showed a lower likelihood of recent dental and veterinary visits. …”
Get full text

Tapinarof Improved Outcomes and Sleep for Patients and Families in Two Phase 3 Atopic Dermatitis Trials in Adults and Children by Eric L. Simpson, Adelaide A. Hebert, John Browning, Rocco T. Serrao, Howard Sofen, Philip M. Brown, Stephen C. Piscitelli, David S. Rubenstein, Anna M. Tallman

“…Results Mean baseline DLQI, CDLQI, IDQOL, and DFI scores indicated that the impact on families and patients’ quality of life (QoL) of AD was moderate to very large. Mean POEM scores indicated moderate to severe AD symptoms at baseline. …”
Get full text

Atrial flutter/fibrillation in adult congenital heart disease: Insights from a large Asian cohort by Shuenn-Nan Chiu, Wei-Chieh Tseng, Chun-Wei Lu, Ming-Tai Lin, Chun-An Chen, Jou-Kou Wang, Mei-Hwan Wu

“…Risk factors for AF/AFL included severe and moderate CHD, PH, previous interventions, and male sex (odds ratio 11.2 and 3.15, 2.03, 1.75, and 1.71, respectively). …”
Get full text

Risk factors for growth retardation in children with juvenile idiopathic arthritis: a case-control study by Ying Zhang, Liping Song, Weihu Ma, Ye Wang, Peipei Wang, Xiaolin Zhang, Zhe Zhang, Yuan Zhang, Qianhui Yu, Yang Yu, Lin Zhang

“…While each of these factors demonstrates moderate predictive value individually, their combined consideration significantly improves predictive accuracy. …”
Get full text

Do Complications After Pancreatoduodenectomy Have an Impact on Long-Term Quality of Life and Functional Outcomes? by Ajami Gikandi, BA, Zhi Ven Fong, MD, MPH, DrPH, Motaz Qadan, MD, PhD, Raja R. Narayan, MD, MPH, Thinzar Lwin, MD, MS, Carlos Fernández-del Castillo, MD, Keith D. Lillemoe, MD, Cristina R. Ferrone, MD

“…Clinical relevance (CR) was scored as small (5–10), moderate (10–20), or large (>20). Patients were stratified based on whether they experienced a complication during the index hospitalization. …”
Get full text

Maximal and Explosive Muscle Strength During Hip Adduction Squeeze and Hip Abduction Press Test Using A Handheld Dynamometer: An Intra- and Inter-tester Reliability Study by Lasse Ishøi, Kristian Thorborg, Laura Krohn, Lars Louis Andersen, Asger Møller Nielsen, MIkkel Bek Clausen

“…Remaining tests for intra- and inter-tester reliability showed moderate reliability (ICC: 0.50-0.71). # Conclusion Assessment of maximal isometric strength in hip adduction squeeze and abduction press test showed good intra- and inter-tester reliability, whereas only 0-200 ms rate of force development demonstrated good intra-tester reliability of both tests. …”
Get full text

Association Between Single-Nucleotide Polymorphisms in <i>Toll-like Receptor 3</i> (<i>tlr3</i>), <i>tlr7</i>, <i>tlr8</i> and <i>tirap</i> Genes with Severe Symptoms in Children P... by Adriana Souza Andrade, Aline Almeida Bentes, Lilian Martins Diniz, Silvia Hees Carvalho, Erna Geessien Kroon, Marco Antonio Campos

“…Comparing severe and critical cases to mild and moderate cases, we found a higher relative risk associated with mutations in <i>tlr8 (1)</i>, <i>tlr7</i>, <i>tlr3</i>, and <i>tirap</i> (<i>p</i> < 0.05). …”
Get full text

Unilateral Toxic Anterior Segment Syndrome Resulting in Cataract and Urrets-Zavalia Syndrome after Sequential Uneventful Implantation of a Posterior Chamber Phakic Toric Intraocula... by Kepa Balparda, Claudia Marcela Vanegas-Ramirez, Johny Márquez-Tróchez, Tatiana Herrera-Chalarca

“…Phakic Intraocular Lens (P-IOL) implantation is a safe, easy, predictable intervention designed to manage moderate to high refractive errors. Complications are relatively uncommon and include mainly cataract and intraocular pressure spikes. …”
Get full text

Childhood BMI trajectories and sociodemographic factors in an Italian pediatric population by Erich Batzella, Joaquin Gutierrez de Rubalcava Doblas, Gloria Porcu, Silvia Bressan, Elisa Barbieri, Carlo Giaquinto, Anna Cantarutti, Cristina Canova

“…Four BMI z-scores trajectories, all with quadratic shape, were identified as the optimal fit: “stable-low-weight” (27.5%), “normal-weight” (40.9%), “stable-moderate-increase” (24.2%), and “overweight-to-obese” (7.5%). …”
Get full text

Danish mothers of young children adhere less to international physical activity guidelines compared with mothers of older children by Solvej Videbæk Bueno, Sebastian Deisting Skejø, Rasmus Oestergaard Nielsen, Knud Ryom, Per Kallestrup, Peter Elsborg, Christina Bjørk Petersen, Julie Sandell Jacobsen

“…The primary outcome was weekly hours of moderate-to-vigorous physical activity, dichotomized into adherers or non-adherers to WHO guidelines. …”
Get full text

Clinical characteristics of patients with coronary artery disease by smoking status by Olga V. Nakhratova, Daria P. Tsygankova, Joseph M. Tsenter, Evgeny D. Bazdyrev

“…RESULTS: More than half of patients with CAD had mild [34 (31.8%)] or moderate [33 (30.8%)] nicotine dependence, and a quarter of patients had high [25 (23.4%)] or very high [15 (14%)] dependence. …”
Get full text

Experience in the Management of Patients with Chronic Vascular Ulcers of the Lower Limbs Using Negatively Charged Polystyrene Microspheres by María Teresa Cacua Sánchez

“…In terms of wound severity, 47% were found to be severe, 43% moderate, and 10% mild. The median time of lesion onset was 28 weeks, with a maximum of 2080 and a minimum of 8 weeks. …”
Get full text

Psychological detachment from work predicts mental wellbeing of working-age adults: Findings from the 'Wellbeing of the Workforce' (WoW) prospective longitudinal cohort study. by Holly Blake, Juliet Hassard, Louise Thomson, Wei Hoong Choo, Teixiera Dulal-Arthur, Maria Karanika-Murray, Lana Delic, Richard Pickford, Lou Rudkin

“…Low psychological detachment from work was more prevalent in the first wave (T1: 21.4% and T2: 16.0%), with a moderate improvement observed from T1 to T2 (t (129) = -7.09, p < .001). …”
Get full text

Circulating Irisin Levels in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis by Jie Hu, Yani Ke, Fangping Wu, Shan Liu, Conghua Ji, Xiaohong Zhu, Ying Zhang

“…Subgroup analysis including 3 studies from Asia suggested that the irisin levels were higher in mild NAFLD than in moderate-severe NAFLD (WMD=11.68 (9.03, 14.32) ng/ml, P<0.05). …”
Get full text

An Evaluation of the Biocompatibility and Chemical Properties of Two Bioceramic Root Canal Sealers in a Sealer Extrusion Model of Rat Molars by Shintaro Takahara, Naoki Edanami, Razi Saifullah Ibn Belal, Kunihiko Yoshiba, Shoji Takenaka, Naoto Ohkura, Nagako Yoshiba, Susan Gomez-Kasimoto, Yuichiro Noiri

“…Additionally, inflammation around the extruded EBC and NBG was minimal to mild on Day 28, whereas moderate inflammation was found around the extruded AHP. …”
Get full text