miR-21 and cathepsin B in familial Mediterranean fever: novel findings regarding their impact on disease severity by Emrah Yucesan, Mehmet Yildiz, Ramila Hajiyeva

“…Only miR-21-5p was negatively correlated with IL-1β (r=−0.855; p<0.001). In moderately severe FMF patients, miR-21-5p exhibited a statistically significant downregulation (p<0.001), whereas IL-1β and cathepsin B showed a statistically significant increase (p<0.001 and p<0.05, respectively). …”
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Obstacle Avoidance for Ship Navigation Safety Combining Heuristic Search Algorithm and Improved ACO Algorithm by Dan Wang, Yan Jing

“…The experimental results show that in simple environments, the hybrid algorithm reduces the path length by 3.8 and 5.5, and the number of iterations by 13.2 and 30.7 compared to Line-of-Sight and Particle Swarm Optimisation algorithms respectively. In moderately complex environments, the proposed algorithm reduces the average path length by 6.51 and 3.93 compared to Particle Swarm Optimisation and Line-of-Sight algorithms respectively. …”
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Pediatric Intensive Care Unit Admissions for COVID-19: Insights Using State-Level Data by Rohit S. Loomba, Enrique G. Villarreal, Juan S. Farias, Ronald A. Bronicki, Saul Flores

“…Children above 11 years of age comprised 69.7% of the total cohort and 35.1% had moderated or severe comorbidities. The median duration of a CPA was 4.9 days (1.25–12.00 days). …”
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Immunoexpression of P16 and Ki 67 in oral squamous cell carcinoma: Association with clinicopathological parameters. by Shadan Mohamad Omer, Payman Anwar Rashid

“…Histopathological findings of the tumor showed that (54.0%) of the patients had moderately differentiated squamous cell carcinoma. However, (84.0%) of the patients showed negative expression of P 16, while Ki 67 expression was positive among (76.0%) of them. …”
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Association between Life’s Crucial 9 and overactive bladder: the mediating role of weight-adjusted-waist index by Hongyang Gong, Hongyang Gong, Shuqin Duan, Shaoqun Huang

“…This study investigates the relationship between LC9 and OAB and assesses whether WWI moderates this relationship.MethodsData for this study came from the National Health and Nutrition Examination Survey (NHANES). …”
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The Restoration Effect of Degraded Grassland Depends on the Response of Species Root Distribution to Resource Availability by Yiming Zhao, Hui Li, Fei Peng, Dabu Xilatu, Qing Chen, Shan Lin

“…Field experiments were conducted using isotope techniques in conjunction with a specialized experimental design at a semiarid grassland location featuring heavily grazed (HG) and moderately grazed (MG) grassland sites with different dominant species. …”
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CHRONOTYPE AND DAILY FUNCTIONING OF PATIENTS WITH DIFFERENT MOTOR SUBTYPES OF PARKINSON DISEASE by A.D. Shkodina, M. Bardhan, K.A. Tarianyk, M. Yu. Delva

“…Light exposure indirectly moderately correlated with mid-sleep in all study groups. …”
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Patient Surgical Outcomes When Surgery Residents Are the Primary Surgeon by Intensity of Surgical Attending Supervision in Veterans Affairs Medical Centers by T. Michael Kashner, PhD, JD, MPH, Paul B. Greenberg, MD, MPH, Andrea D. Birnbaum, MD, PhD, John M. Byrne, DO, Karen M. Sanders, MD, Mark A. Wilson, MD, PhD, Marjorie A. Bowman, MD, MPA

“…Estimates were tested for any residual confounding biases, robustness to different regression models, stability over time, and validated using moderator and secondary factors analyses. Results:. …”
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The effect of blood glucose levels on serum triglyceride clearance in patients with hyperlipidemic acute pancreatitis by Yuxin Liu, Shuqi Qin, Si Dai, Jing Zhou, Zhendan Wang, Guojian Yin

“…Abstract Preventing moderately severe and severe acute pancreatitis (MSAP & SAP) is the primary goal of the management of hyperlipidemic acute pancreatitis (HLAP). …”
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Water use dynamics of almond and pistachio crops in the Mediterranean region amid climate change by Anshika Kandhway, Fabio Scarpare, Mingliang Liu, Roger Nelson, Jennifer C. Adam, Ray G. Anderson, Martha H. Conklin, Mohammad Safeeq

“…The eCO2 is expected to moderately reduce irrigation demand by 35 million m3/year for almonds and increase by 140 million m3/year for pistachios over the baseline. …”
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Determinants of well-being and their interconnections in Australian general practitioners: a qualitative study by Nick Glozier, Ian B Hickie, Christiane Klinner, Alyssa Milton, Diana Naehrig, Louise Acland, Brendan Goodger

“…Both personal finances, and funding structures emerged as important moderators of the interconnections between these themes. …”
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In Vitro Free Radical Scavenging Properties and Anti-Inflammatory Activity of Ilex paraguariensis (Maté) and the Ability of Its Major Chemical Markers to Inhibit the Production of... by Ingrid Vicente Farias, Eduarda Fratoni, Lais Cristina Theindl, Angela Machado de Campos, Eduardo Monguilhott Dalmarco, Flavio Henrique Reginatto

“…Our results suggest that I. paraguariensis and its major chemical markers have strong free radical scavenging properties as well as showed important anti-inflammatory activity and that these compounds in a plant extract may work based on several different mechanisms synergistically, resulting in moderating the immune system.…”
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Substitution of manure source and aerator in nursery media on sandy loam topsoil and their fertility indices 4 months after formulation by C. V. Adubasim, C. M. Igwenagu, G. O. Josiah, S. E. Obalum, U. M. Okonkwo, I. M. Uzoh, S. Sato

“…The substitution also enhanced available phosphorus in topsoil+droppings+huskdust (117.50 mg kg−1) and topsoil+dung+huskdust (71.50 mg kg−1) but reduced K+ in the latter where it too had moderating effects on Na+. Reference surpassed topsoil+slurry+huskdust for Ca2+, but was surpassed by topsoil+droppings+huskdust for Mg2+. …”
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The intermediary effect of work stress on the relationship between off-duty professional growth and reflective ability among mid- and senior-level nurses by Junxian Wu, Jingru Song, Mingfang Zhang, Lin Li, Qin Shen

“…Conclusion This study demonstrates that the reflective ability of mid- to senior-level nurses in China is currently at a moderately low level. Enhancing Off-duty professional growth, leveraging the beneficial aspects of challenge stress, and reducing the negative effects of hindrance stress can notably improve reflective ability. …”
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Correlations between caregiver competence, burden and health-related quality of life among Chinese family caregivers of elderly adults with disabilities: a cross-sectional study us... by Yan Shi, Shuzhen Niu, Silian Ding, Songqi Wu, Jiajia Ma

“…Caregiver competence was assessed using the Family Caregiver Task Inventory, and caregiver burden was assessed with the Zarit Burden Interview.Results Caregivers of moderately and severely disabled elderly adults showed poorer scores in Physical Component Summary (F=20.463, p<0.05) and Mental Component Summary (F=17.062, p<0.05) compared with caregivers of older adults with mild disabilities. …”
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Patient-reported systemic symptoms in women with silicone breast implants: a descriptive cohort study by Karlinde Amber Spit, Miranda Scharff, Christel JM de Blok, Frank B Niessen, Yara Bachour, Prabath W Nanayakkara

“…Symptoms improved significantly in 65 women (43%), improved moderately in 37 women (24%), did not change in 37 women (24%) and deteriorated in 13 women (9%). …”
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A Pilot Study Assessing Left Ventricle Diastolic Function in the Parasternal Long-axis View by Mümin Murat Yazici, Nurullah Parça, Enes Hamdioğlu, Meryem Kaçan, Özcan Yavas¸i, Özlem Bilir

“…Similarly, the correlation between E in spectral Doppler measurements and the EPSS/APSS ratio in M-mode measurements was also moderately strong (correlation coefficient 0.557, P = 0.001). …”
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Impact of a potential Chlamydia vaccine in the USA: mathematical modelling analyses by Hiam Chemaitelly, Laith J Abu-Raddad, Houssein H Ayoub, Susanne F Awad, Monia Makhoul

“…Vaccination benefits were larger beyond 10 years.Conclusion A moderately efficacious CT vaccine can significantly reduce CT disease burden. …”
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Prebreeding research of near-isogenic lines of spring bread wheat with a combination of translocations from Agropyron elongatum (Host.) Р.В. and Aegilops ventricosa Tausch. by S. N. Sibikeev, A. E. Druzhin

“…Phytopathological tests showed that L653 and L654 were highly resistant to Puccinia triticina at all stages of plant development and to Puccinia graminis race Ug99 + Lr24 (TTKST), but they were moderately susceptible to the Saratov population of this pathogen. …”
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Psychological aspects of patients with breast cancer depending on the presence of visible postoperative defect by A. D. Zikiryakhodzhaev, M. V. Ermoschenkova, N. A. Sirota, B. A. Fetisov

“…The results of the study of women in both groups indicate that the patients are moderately using coping strategies for coping with the disease, preferring the strategy of "problem resolution" and "search of social support". …”
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