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  1. 5881

    Phytochemical and Biological Investigations of Crude Extracts of <i>Astragalus pisidicus</i> by Esra Aydemir, Elif Odabaş Köse, Serap Özkaya Gül, Alaaddin Korkut, A. Cansu Kilit, Mehmet Engin Celep, Mustafa Yavuz, R. Süleyman Göktürk, Cengiz Sarikurkcu

    Published 2024-12-01
    “…Fm (IC<sub>50</sub> = 9.57 µg/mL), Rm (IC<sub>50</sub> = 14.89 µg/mL), and Sm (IC<sub>50</sub> = 9.57 µg/mL) were evaluated as active crude extracts on H1299, HT-29, and Panc-1 cells, while Rm (IC<sub>50</sub> = 32.057 µg/mL) and Fm (IC<sub>50</sub> = 64.25 µg/mL) were assessed as moderately active on MCF-7 and 22RV1 cells, respectively. …”
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  2. 5882

    The Role of β-Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis by Kunlong Xiong, Jinxia Niu, Ruijuan Zheng, Zhonghua Liu, Yanzheng Song, Lin Wang, Changtai Zhu, Lin Fan

    Published 2021-01-01
    “…The stimulation of peripheral blood mononuclear cells (PBMCs) with lithium chloride (LiCl), a stimulant of β-catenin, resulted in the increase in CD4+ T cell frequency, as well as their secretion of IFN-γ and TNF-α. β-Catenin demonstrated a moderately positive correlation with PD-1 in CD4+ T cells. β-Catenin along with PD-1 and IFN-γ in CD4+ T cells had a high correlation with those in CD8+ T cells. …”
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  3. 5883

    Study protocol of a randomised controlled trial on SISU, a software agent providing a brief self-help intervention for adults with low psychological well-being by Harald Baumeister, Ann-Marie Küchler, David Ebert, Natalie Bauereiss, Eileen Bendig, Benjamin Erb, Lena Weger, Echo Meißner

    Published 2021-02-01
    “…Examined mediators and moderators are sociodemographic variables, personality (Big Five Inventory-10), emotion regulation (Emotion Regulation Questionnaire), alexithymia (Toronto Alexithymia Scale-20), centrality of events (Centrality of Events Scale), treatment expectancies (Credibility Expectancy Questionnaire) and technology alliance (Inventory of Technology Alliance–Online Therapy). …”
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  4. 5884

    The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis by Jingmin Song, Heqing Wang, Xiaolian Gao, Fen Yang, Xinhong Zhu, Guiyuan Qiao, Ting Gan, Junxiu Tao

    Published 2025-02-01
    “…Meta-regression analysis identified the hepcidin measurement method (p < 0.01), male-to-female ratio (p < 0.01), and study quality (p < 0.01) as significant moderators of the observed heterogeneity. Conclusion This meta-analysis revealed a significant association between hepcidin levels, the hepcidin/ferritin ratio and NAFLD in adults. …”
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  5. 5885

    Selective dorsal rhizotomy long-term effects on functional motility in Jordanian children with spastic cerebral palsy by Yazan E. Al-kharabsheh, Anas Said, Ismail A. Ismaiel, Issam Khawaja, Marwan Altaher, Ali Bani-Ahmed, Carmen M. Cirstea, Carmen M. Cirstea

    Published 2025-01-01
    “…Sex, age and clinical scores at surgery, and post-SDR surgical treatment were included in the model (IBM SPSS Statistics 29.0).ResultsClinical scores improved 12 months after SDR: GMFCS decreased by at least one level (in 58.5% of patients), and FMS significantly increased (p &lt; 0.001); GMFCS decreased in 77.7% of those with pre-SDR severe impairment vs. 43.5% in moderately to mildly impaired patients. An age sub-analysis demonstrated higher changes in GMFCS in younger children (GMFCS decreased in 46.9% of those aged &lt;10 years old vs. none in those older than 10 years). …”
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  6. 5886

    Do community-based digital health inclusion programmes contribute to tackling health inequalities in disadvantaged population groups?: a qualitative study of experiences of a city-... by Shoba Poduval, Lily Arnold, Emma Carta, Danielle Nimmons, Irene Stratton, Michael Shaw, Katherine Bradbury, Fiona Stevenson

    Published 2025-01-01
    “…These were: programme components, recipient-centred support, impacts on service-users and system-level barriers to digital health services. Findings suggest moderators of implementation are provision of community spaces, social activities and devices and Wi-fi, and recipient-centred support through community understanding, personalised regular support and trusting relationships. …”
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  7. 5887

    Identification and expression analysis of the heat shock proteins Hsp70, Hsp90, and Hsp90b in Litopenaeus vannamei under low-temperature stress by Min Peng, Hui Wang, Shuiping Wen, Zheng Liang, Zheng Huang, Bin Zhang, Tianchong Chen, Qingyun Liu, Qiangyong Li, Yuan Meng, Yuliu Huang, Chunling Yang, Digang Zeng, Manyuan Li, Weilin Zhu, Yongzhen Zhao

    Published 2025-03-01
    “…Linkage disequilibrium analysis revealed that eight SNPs in hsp70 were significantly associated with low-temperature tolerance (P < 0.01), and 4 SNPs were moderately associated with low-temperature tolerance (P < 0.05). …”
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  8. 5888

    Salt tolerance evaluation and key salt-tolerant traits at germination stage of upland cotton by Mengjie An, Xinhui Huang, Yilei Long, Yin Wang, Yanping Tan, Zhen Qin, Xiantao Ai, Yan Wang

    Published 2025-01-01
    “…The results showed that the 308 germplasms were classified into five classes through cluster analysis, i.e, (1) highly salt-tolerant germplasms (HST, 49), (2) salt-tolerant germplasms (ST, 169), (3) moderately salt-tolerant class (MST,43), (4) lowly salt-tolerant germplasms (LST, 16), and (5) non-salt-tolerant germplasms (NST, 31). …”
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  9. 5889

    Providing a model of emotional and rational appeals in video marketing based on social networks by Moohan Mohammadi, payam paslari, saeed moradpour, sadegh masjoodi

    Published 2024-11-01
    “…In addition, the time of release of videos significantly moderated the relationship between emotionality of short videos and consumer engagement. …”
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  10. 5890
  11. 5891

    Women Empowered to Connect With Addiction Resources and Engage in Evidence-Based Treatment (WE-CARE)—an mHealth Application for the Universal Screening of Alcohol, Substance Use, D... by Krystyna Isaacs, Autumn Shifflett, Kajal Patel, Lacey Karpisek, Yi Cui, Maayan Lawental, Golfo Tzilos Wernette, Brian Borsari, Katie Chang, Tony Ma

    Published 2025-02-01
    “…WE-CARE included screening instruments (for alcohol, substance use, depression, and anxiety), a moderated discussion forum, educational microlearning videos, a frequently asked questions section, and resources for linkage to treatment. …”
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  12. 5892

    Hypofractionated image-guided radiotherapy with 70 Gy in 28 fractions for prostate cancer confined to the pelvis: a single institute experience in Taiwan by Hui-Lei Mu, Mau-Shin Chi, Hui-Ling Ko, Guang-Dar Juang, Thomas I-Sheng Hwang, Kwan-Hwa Chi, Kai-Lin Yang

    Published 2025-01-01
    “…Abstract Background The incidence of prostate cancer is increasing in Asian countries. Although moderately hypofractionated radiotherapy is not inferior to conventional fractionated radiation according to the updated guidelines, data regarding its efficacy and safety in Taiwan are currently lacking. …”
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  13. 5893

    Health-Related Quality of Life in Patients with Friedreich Ataxia Using Mobility Assistive Technologies: Limited Fit of the EQ-5D-3L Mobility Dimension by Maresa Buchholz, Michelle Pfaff, Audrey Iskandar, Kathrin Reetz, Jörg B. Schulz, Marcus Grobe-Einsler, Thomas Klockgether, Bernhard Michalowsky, EFACTS Study Group

    Published 2024-12-01
    “…The mobility item correlated moderately with disease severity (r sp = 0.35) and the activities of daily living scale (r sp = 0.36) in wheelchair users. …”
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  14. 5894

    Proportion, quality of life and factors associated with perinatal urinary incontinence among pregnant women attending at Muhimbili national hospital by Geofrey P. Chiloleti, Fransia Arda Mushi, Aboud Muhsin, Ally Mwanga

    Published 2025-01-01
    “…Overall, among the participants who had PUI, quality of life (QoL) was moderately affected in 31 (52.5%) participants, followed by 17 (28.8%) whose QoL was slightly affected, 10 (16.9%) whose QoL was poor, and only 1 (1.7%) whose quality of life was very poor. …”
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  15. 5895

    Probing the Dual Role of Ca<sup>2+</sup> in the <i>Allochromatium tepidum</i> LH1–RC Complex by Constructing and Analyzing Ca<sup>2+</sup>-Bound and Ca<sup>2+</sup>-Free LH1 Comple... by Mei-Juan Zou, Shuai Sun, Guang-Lei Wang, Yi-Hao Yan, Wei Ji, Zheng-Yu Wang-Otomo, Michael T. Madigan, Long-Jiang Yu

    Published 2025-01-01
    “…The <i>Alc. tepidum</i> LH1, therefore, offers a unique model for studying an intermediate phenotype between phototrophic thermophilic and mesophilic bacteria, particularly regarding their LH1 <i>Qy</i> transition and moderately enhanced thermal stability. Of the 16 α-polypeptides in the <i>Alc. tepidum</i> LH1, six α1 bind Ca<sup>2+</sup> to connect with β1- or β3-polypeptides in specific Ca<sup>2+</sup>-binding sites. …”
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  16. 5896

    Relevant Elements of Standardisation of Federation’s Advisory Programs for Voluntary Sports Clubs by Marisa Moser, Matthias Buser, Siegfried Nagel

    Published 2025-01-01
    “…While research has discussed critical interfaces, little is known about what moderates the translation of advisory input to achieve change at club level (cf. …”
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  17. 5897

    Risk of hemorrhagic fever with renal syndrome associated with meteorological factors in diverse epidemic regions: a nationwide longitudinal study in China by Nan Chang, Wenzhong Huang, Yanlin Niu, Zhihu Xu, Yuan Gao, Tingting Ye, Zihao Wang, Xiaohui Wei, Yuming Guo, Qiyong Liu

    Published 2025-01-01
    “…Targeted preventive measures should be taken during cold and dry spring days in Rattus-dominant regions, and during warm and moderately humid winter days in Apodemus-dominant regions. …”
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  18. 5898

    Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) by Jonathan Brett, Celia Morgan, Nadine Ezard, Brendan Clifford, Krista J Siefried, Robert May, Liam Acheson, Kathryn Fletcher, Harriet MacDonald, Gillinder Bedi, Alexandre Guerin, Elizabeth Knock, Michael Millard, Jess Doumany

    Published 2025-02-01
    “…No pharmacological treatment options currently exist for methamphetamine use disorder, and psychotherapy is only moderately effective. Preliminary evidence suggests that ketamine-assisted psychotherapy produces sustained improvements in substance use and mental health symptomatology. …”
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  19. 5899
  20. 5900

    Response of South Asia PM2.5 pollution to ammonia emission changes and associated impacts on human health by Yuanlin Wang, Eiko Nemitz, Samuel J. Tomlinson, Edward J. Carnell, Liquan Yao, Janice Scheffler, Tomas Liska, Clare Pearson, Ulrike Dragosits, Chandra Venkataraman, Srinidhi Balasubramanian, Rachel Beck, Mark A. Sutton, Massimo Vieno

    Published 2025-01-01
    “…These findings confirm that in the current NH3-rich chemical environment of South Asia, the efficiency of PM2.5 reduction is only moderately sensitive to the reduction in intensity of NH3 emissions until emissions are cut very severely. …”
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