Synthesis and Evaluation of Cytotoxic Activity of RuCp(II) Complexes Bearing (Iso)nicotinic Acid Based Ligands by Bárbara Marques, Diogo M. Engrácia, João Franco Machado, Jaime A. S. Coelho, Filipa Mendes, Tânia S. Morais

“…Conclusions: Both compounds exhibited moderate to high cytotoxic activity, with complex 1 showing a greater propensity to induce cell death, particularly in the A431 and MDA-MB 231 cell lines.…”
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Synergistic Antifungal Activity of Terbinafine in Combination with Light-Activated Gelatin–Silver Nanoparticles Against <i>Candida albicans</i> Strains by Atif Ullah, Fawad Ali, Farman Ullah, Sajid Khan Sadozai, Saeed Ahmed Khan, Sajid Hussain, Abdulwahed Fahad Alrefaei, Sajid Ali

“…Terbinafine demonstrated strong antifungal properties with minimum inhibitory concentrations (MIC) values ranging from 2–4 µg/mL, whereas AgNPs on their own displayed moderate effectiveness. The integrated formulation notably enhanced effectiveness, especially against strain ATCC 90028, revealing a synergistic effect (FIFi = 0.369). …”
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Is Dry Needling Effective When Combined with Other Therapies for Myofascial Trigger Points Associated with Neck Pain Symptoms? A Systematic Review and Meta-Analysis by César Fernández-De-Las-Peñas, Gustavo Plaza-Manzano, Jorge Sanchez-Infante, Guido F Gómez-Chiguano, Joshua A Cleland, José L. Arias-Buría, Ibai López-de-Uralde-Villanueva, Marcos J. Navarro-Santana

“…No significant effects on cervical range of motion or pain catastrophism were observed. Conclusion. Low-to-moderate evidence suggests a positive effect to the combination of dry needling with other interventions for improving pain intensity, pain-related disability, pressure pain thresholds, and cervical range of motion in people with neck pain associated with TrPs at short-term. …”
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Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women by Maha Sellami, Shamma Almuraikhy, Khaled Naja, Najeha Anwardeen, Hadaia Saleh Al-Amri, Mohammad Shoaib Prince, Amina Ali Aden, Alexander Doemling, Mohamed A. Elrayess

“…This study aims to explore the effects of 4 and 8 weeks of moderate-intensity aerobic exercise on glucose metabolism, lipid profiles, and associated metabolic changes in young female students with insulin resistance and varying body mass, seeking to determine the optimal duration for physiological adaptations. …”
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Knowledge, attitude, and reasons for non-uptake of human papilloma virus vaccination among nursing students by Soni Chauhan, Surya Kant Tiwari, Vishal Dubey, Pragya Tripathi, Priyanka Pandey, Anuj Singh, Narendra Pal Singh Choudhary

“…About half of the participants demonstrated moderate knowledge (52.4%) and negative attitudes (50.1%) towards HPV vaccination, with none having received the vaccine. …”
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Association of workforce participation with depression among US older adults: results from NHANES 2005–2018 by Zhenyu Sun, Yi Wang, Xi Chen, Dongfu Qian

“…Policymakers should appreciate the potential value of moderate workforce participation to mental health among older adults.…”
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Gait kinematics at trot before and after repeated ridden exercise tests in young Friesian stallions during a fatiguing 10-week training program by Esther W. Siegers, Jeanne I. M. Parmentier, Jeanne I. M. Parmentier, Marianne M. Sloet van Oldruitenborgh-Oosterbaan, Carolien C. B. M. Munsters, Filipe M. Serra Bragança

“…Linear mixed models were used to analyze gait variables related to SET, pre-or post-SET and a peak LA ≥4 mmol/L during SETs.ResultsHorses showed individual responses in gait kinematics to moderate fatigue. The range of motion of the withers (ROMwithers) increased post SET-II and SET-III compared to post SET-I. …”
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GWAS Identifies SNP Markers and Candidate Genes for Off-Flavours and Protein Content in Faba Bean (<i>Vicia faba</i> L.) by Antonio Lippolis, Boudewijn Hollebrands, Valentina Acierno, Catrienus de Jong, Laurice Pouvreau, João Paulo, Salvador A. Gezan, Luisa M. Trindade

“…The CGN population showed large phenotypic variation and moderate-to-high narrow-sense heritability for most traits. …”
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Diabetic retinopathy further increases risk of cardiovascular disease mortality in a high-risk cohort by Richard Kha, Yasemin Kapucu, Mayuri Indrakumar, George Burlutsky, Aravinda Thiagalingam, Pramesh Kovoor, Paul Mitchell, Gerald Liew

“…Participants were concurrently examined for DR from mydriatic fundus photographs which were mask-graded according to International Clinical Classification categories of no DR, mild non-proliferative DR, moderate-to-severe NPDR, and proliferative DR. Coronary artery disease was graded from coronary angiograms using the Gensini score. …”
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Dissociation between Cerebellar and Cerebral Neural Activities in Humans with Long-Term Bilateral Sensorineural Hearing Loss by Xiao-Min Xu, Yun Jiao, Tian-Yu Tang, Jian Zhang, Chun-Qiang Lu, Ying Luan, Richard Salvi, Gao-Jun Teng

“…Twenty-one subjects with long-term bilateral moderate-to-severe sensorineural hearing loss and 21 matched controls with clinically normal hearing underwent MRI scanning and a series of neuropsychological tests targeting cognition and emotion. …”
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Identification and Analysis of Potential Immune-Related Biomarkers in Endometriosis by Yanan He, Jixin Li, Yanjun Qu, Liyuan Sun, Xibo Zhao, Han Wu, Guangmei Zhang

“…Most downregulated DETFs showed decreased expression in the endometria of moderate/severe endometriosis patients. The top-ranked upregulated DEIRGs were upregulated in the endometra of infertile women. …”
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Risk assessment and hierarchical classification of foodborne disease epidemics during major events in Beijing: an empirical study based on surveillance data analysis by Jinru JIANG, Yangbo WU, Tongyu WANG, Chao WANG, Yanlin NIU, Di WANG, Liping LI, Qian CHEN, Yao ZHAO, Xiaochen MA

“…The risk levels of foodborne disease in both the key population and the general population were concentrated in the high risk (H), moderate risk (M), and low risk (L) levels. For the key population, there were 5 H-level risk factors (20%), 11 M-level risk factors (44%), and 9 L-level risk factors (36%), of which rodenticides and tetrodotoxin poisoning were the most important risk factors. …”
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How does the concentration of spatial allocation of urban construction land across cities affect carbon emission intensity in China? by Hui Yang, Cheng Chen, Jingye Li, Min Li, Stefan Sieber, Kaisheng Long

“…Optimizing the spatial allocation of urban construction land (UCL) from the national perspective and promoting its moderate concentration are imperative prerequisites for synergistically accomplishing economic growth and carbon emission reduction goals. …”
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Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…Differences were observed between PRE and PERI versus POST with respect to variable selection in parity and FHx. Our models had moderate discriminatory accuracy. AUCs (confidence intervals) of the PRE, PERI, and POST models were 0.669 (0.625–0.715), 0.669 (0.632–0.702), and 0.659 (0.627–0.693), respectively. …”
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Efficacy and safety of intermittent fasting for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized trials by Joshua Chadwick, Lavanya Ayyasamy, Madhanraj Kalyanasundaram, Ganeshkumar Parasuraman, Bhavani Shankara Bagepally, Jeyashree Kathiresan, Lokesh Shanmugam

“…Interpretation &amp; conclusions: On the basis of moderate to low certainty of evidence, IF can be a safe dietary approach for patients with T2DM, with similar safety and effectiveness profiles to regular diets. …”
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Concordance of Australian state and territory government guidelines for classifying the healthiness of foods in public settings by Bettina Backman, Meg Adam, Jasmine Chan, Josephine Marshall, Emalie Rosewarne, Gary Sacks, Adrian J Cameron, Miranda R Blake

“…The largest proportion of discrepancies (58%) were attributed to whether products were classified as ‘Red’ (least healthy) or ‘Amber’ (moderately healthy). Conclusions: Results indicate only moderate concordance between all guidelines. …”
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Optimum technique of carotid artery reconstruction in her atherosclerotic lesion by V. V. Akhmetov, V. I. Dunaeva, F. A. Vryganov, S. V. Ordynets, I. P. Dudano

“…All patients had significant (moderate to severe) carotid stenosis. After the operation 5 (0.4%) patients had ischemic stroke, 1 (0.08%) had n. hypo-glossus damage, 3 (0.24%) had postoperative hematoma. …”
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Compassion fatigue and associated factors among nurses working in Jimma Zone public hospitals, southwest Ethiopia: A facility based cross-sectional study. by Duguma Debela Ganeti, Bikila Dereje Fufa, Ebissa Bayana Kebede, Sheka Shemsi Seid, Birhanu Wogane Ilala, Nuritu Bacha Benti, Yeshitila Belay Belachew

“…<h4>Result</h4>From a total of 422 respondents, 412(97.6%) of them gave complete responses. 47% of respondents, had a moderate level of compassion fatigue. Total experience [β = -0.04; 95%CI (-0.06, -0.01); p = 0.005], perceived social support [β = -0.13; 95% CI (-0.17, -0.08); p<0.001], self-compassion [β = -0.09; 95% CI (-0.14, -0.03); p = 0.003], support seeking [β = -0.23; 95% CI (-0.42, -0.04 p = 0.017], emergency ward [β = 0.36; 95% CI (0.2, 0.51); p <0.001], ICU [β = 0.38; 95% CI (0.21, 0.54); p<0.001], pediatric ward [β = 0.23; 95% CI (0.10, 0.36); p < 0.001] and average sleep hours per day [β = 0.46; 95% CI (0.35, 0.57); p<0.001] were statistically signifantly factors.…”
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Blood Cell Ratio Combinations for Diagnosing Periprosthetic Joint Infections: A Preliminary Study by Yu Y, Wen Y, Xia J, Dong G, Niu Y

“…PAR and CAR were confirmed to have high diagnostic values, with AUC values of 0.779 and 0.718, respectively. CALLY exhibited moderate diagnostic effectiveness, with an AUC of 0.647. …”
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Outcomes and Complications of Minimally Invasive Glaucoma Surgeries (MIGS) in Primary Angle Closure and Primary Angle Closure Glaucoma: A Systematic Review and Meta-Analysis by Paik B, Chua CH, Yip LW, Yip VC

“…MIGS should be thoroughly considered for mild-moderate PACG with coexisting cataract before pursuing more invasive surgical approaches.Keywords: MIGS, glaucoma, angle closure, surgery…”
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