Prednisolone versus antihistamine for allergic rhinitis: No significant difference found in randomized trial by Carl Skröder, Laila Hellkvist, Ulla Westin, Pernilla Sahlstrand‐Johnsson, Kerstin Hansson, Agneta Karlsson, Åslög Dahl, Leif Bjermer, Lars Olaf Cardell

“…Objective To compare the effectiveness of prednisolone tablets versus antihistamine tablets in reducing symptoms and medication usage in patients with moderate to severe tree pollen‐induced AR. Methods This interventional single‐center, double‐blinded randomized trial included 34 patients. …”
Get full text

THE EFFECT OF THE AGE OF SMOOTH BROME (BROMOPSIS INERMIS) STANDS ON THEIR HERBAGE YIELD IN TYUMEN PROVINCE by N. A. Feoktistova

“…Haymakinggrazing group: accessions with medium productivity in the 1st year of utilization (24–27 t/ha) and its moderate reduction by 42–64% to the 4th year of utilization can be used in forage rotations for 5–7 years (‘Argonavt’; ‘Ingair’; ‘Stepasha’; ‘Yarilo’; 7-1-54; 15-2-63; 4-4-17; 7-4-49; 4-2-20). …”
Get full text

Effect of ozone oil and non-surgical periodontal treatment in patients with type 2 diabetes. In-vivo and in-vitro studies with fibroblasts and Candida albicans by Raquel Alves do CARMO, Ana Carolina Organista CÖRNER, Eduardo Ferreira MARTINS, Gabriel OUVERNEY, Julio Cesar THURLER JÚNIOR, Bruno Kaufmann ROBBS, Vinicius D’Avila Bitencourt PASCOAL, Elisa ESPOSITO, Luciane Portas CAPELO, Gabriela Alessandra da Cruz Galhardo CAMARGO

“…Methodology In total, 32 sites in 16 DM2 with moderate to advanced periodontal disease with periodontal pocket depths ≥5mm were selected. …”
Get full text

Selective and persistent toxicity of seven insecticides to five egg parasitoids of Spodoptera frugiperda by Hao-Ran Li, Cheng-Yang Li, Peng Dai, Lian-Sheng Zang, Nicolas Desneux, Wei Xu

“…Conversely, spinetoram and emamectin benzoate displayed moderate toxicity to adults of all tested parasitoid species. …”
Get full text

Development of an in vitro triculture model of intestine inflammation to assess the immunomodulatory properties of cassava and roselle, two African green leafy vegetables by Nelly Fioroni, Maria Del Carmen Ponce de León Rodríguez, Nicolas Leconte, Claire Mouquet-Rivier, Caroline Guzman, Frédéric Boudard, Claudie Dhuique-Mayer, Myriam Collin, Anaïs Deglos, Emmanuelle Reboul, Ángela Bravo-Núñez, Caroline Laurent-Babot

“…The developed and validated triculture model of inflamed intestine thus demonstrated the anti-inflammatory properties of cassava and roselle leaves, despite moderate responses.…”
Get full text

Impact of COVID-19 restrictions on behavioural and psychological symptoms in home-dwelling people with dementia: a prospective cohort study (PAN.DEM) by Maarja Vislapuu, Mala Naik, Bettina S Husebø, Marie H Gedde, Ipsit V Vahia, Janne Mannseth, Line I Berge

“…Objectives To investigate the impact of the COVID-19 restrictions on behavioural and psychological symptoms of dementia (BPSD).Design Prospective cohort study (PAN.DEM) nested within the halted parent trial (LIVE@Home.Path).Setting Households in Norway immediate before and 6–9 weeks into the COVID-19 restrictions.Participants 104 dyads (persons with mild to moderate dementia aged ≥65 and their informal carers) completed both prepandemic and pandemic assessments, among 237 in the parent trial. …”
Get full text

Evaluation of ChatGPT-4 for the detection of surgical site infections from electronic health records after colorectal surgery: A pilot diagnostic accuracy study by Josep M. Badia, Daniel Casanova-Portoles, Estela Membrilla, Carles Rubiés, Miquel Pujol, Joan Sancho

“…It appears to be a useful tool for initial screenings and for reducing manual review workload. The moderate specificity suggests a need for further refinement to reduce the rate of false positives. …”
Get full text

Tuberculosis and Sudden Death in Lithuania by Gintarė Zarembaitė, Gabrielė Žiūkaitė, Sigitas Chmieliauskas, Diana Vasiljevaitė, Sigitas Laima, Jurgita Stasiūnienė

“…Regarding socioeconomic factors, a moderate negative correlation between Lithuania’s gross domestic product and tuberculosis distribution was observed, as well as a weak negative correlation between alcohol consumption (l per capita) in the general population and tuberculosis distribution. …”
Get full text

Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters: Application of Infrared Fundus Photography in Assessing the Treatment Efficacy by Xiaolei Sun, Jingyi Tian, Jinyan Wang, Jingjing Zhang, Ying Wang, Gongqiang Yuan

“…Severe symptoms were reported in 17 eyes, moderate in 21 and mild in 17 eyes. No severe Nd:YAG vitreolysis procedure-related complications occurred in all patients except one mild retinal injury. …”
Get full text

Exploring the Role of the Pharmacist in the Prevention and Management of Hypertensive Disorders in Pregnancy in Ashanti Region, Ghana by Pauline Boachie‐Ansah, Berko Panyin Anto, Afia Frimpomaa Asare Marfo, Edward Tieru Dassah, Morrison Asiamah, Ivan Eduku Mozu, Nana Ofori Adomako, Kwaku Gyamfi Oppong

“…The study was carried out among pregnant women with moderate to high risk of developing HDPs and seeking antenatal care at a university hospital in Kumasi, Ghana. …”
Get full text

Evaluating the impact of roof rainwater harvesting on hydrological connectivity and urban flood mitigation by Quang-Oai Lu, Reza Bahramloo, Jesús Rodrigo-Comino, Jun Wang, Ali Talebi, Quynh Thi Phuong Tran, Afshin Ghahramani, Mehdi Sepehri

“…The areas characterized by very high and high degrees of hydrological connectivity in the absence of Roof rainwater harvesting decreased to 11.4 % and 20.4 %, respectively. Conversely, the moderate, low, and very low hydrological connectivity categories experienced increases of 27.9, 28.4, and 11.7 %, respectively. …”
Get full text

Understanding and reducing delayed dental care for early childhood caries: a structural equation model approach by Mengmeng Wang, Yu Zhang, Xiaofei Li, Xin Liu

“…Results The treatment delay score of early childhood caries was 36.77 ± 10.11, indicating that the state of early childhood caries was currently at a moderate level of delay. The SOHO-5 score was 6.41 ± 1.78, the CFSS-DS-C score was 23.60 ± 6.91, the P-CPQ-8 score was 18.43 ± 4.33, and the FIS-8 score was 18.66 ± 4.28. …”
Get full text

Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors by Alejandro Diaz-Barreiro, Dominique Talabot-Ayer, Arnaud Huard, Gea Cereghetti, Jenna Tonacini, Mike Maillasson, Antonio Francés-Monerris, Erwan Mortier, Gaby Palmer

“…The recombinant IL-38 proteins bound to the IL-36R with only moderate affinity, which may provide a mechanistic explanation for inefficient IL-36R antagonism. …”
Get full text

Source and Ecological Risk Assessment of Potentially Toxic Metals in Urban Riverine Sediments Using Multivariate Analytical and Statistical Tools by Xiaojun Zheng, Abdul Rehman, Shan Zhong, Shah Faisal, Muhammad Mahroz Hussain, Syeda Urooj Fatima, Daolin Du

“…Furthermore, the geochemical pollution indices showed that sediments were moderately polluted with Cd (<i>I</i>_geo = 2.37, EF = 12.1, and CF = 7.89) and extremely polluted with Hg (<i>I</i>_geo = 4.54, EF = 63.2, and CF = 41.41). …”
Get full text

The relationship between social support and psychological crisis vulnerability among family impoverished undergraduates: the intermediary role of psychological resilience by Weimin Yuan, Jinhui Ning, Mengke Huo, Yiwei Feng

“…Finally, we employed a structural equation modeling approach to analyze the underlying mechanisms between social support and psychological crisis vulnerability and to test the conspicuousness of the mediating role of psychological resilience in the process by which social support affects psychological crisis vulnerability.ResultsAnalysis of 1,549 valid questionnaires revealed that the overall level of psychological crisis vulnerability among family impoverished undergraduates was moderate. Among the surveyed family impoverished undergraduates, 37.62% reported difficulty in maintaining psychological balance when facing crises, and 4.73% showed a very vulnerable response to crises. …”
Get full text

Rationale and design of the HOVON 170 DLBCL-ANTICIPATE trial: preventing anthracycline-induced cardiac dysfunction with dexrazoxane by Marijke Linschoten, Jesse Geels, Erik van Werkhoven, Heleen Visser-Wisselaar, Martine E. D. Chamuleau, Arco J. Teske, Lourens Robbers, Simone Oerlemans, Heleen Crommelin, Marleen Breems-de Ridder, Astrid Schut, Folkert W. Asselbergs, Anna van Rhenen, on behalf of the HOVON 170 DLBCL – ANTICIPATE consortium

“…This is related to the low to moderate quality of the generated evidence, safety concerns and restricted prescribing indications. …”
Get full text

Variations of microbiota and metabolites in rhizosphere soil of Carmona microphylla at the co-contaminated site with polycyclic aromatic hydrocarbons and heavy metals by Ying Zhang, Fanghan Qian, Yanyu Bao

“…In this study, an operating ink factory site co-contaminated with polycyclic aromatic hydrocarbons (PAHs, mild to moderate pollution level) and heavy metals (HMs, heavy pollution level) was selected and screened for native vegetation, Carmona microphylla. …”
Get full text

Latent profile and determinants of self-management behaviors among older adult patients with chronic diseases: a cross-sectional study by Yu Jiao Shao, Xiao Cui Duan, Xue Jun Xu, Hong Yan Guo, Ze Yu Zhang, Shuang Zhao, Fu Zhi Wang, Yong Xia Chen, Qin Chen, Shi Qing Zhang, Xiu Mu Yang

“…Latent profile analysis was conducted using Mplus 8.3, and univariate and multivariate logistic regression analyses were performed using SPSS 26.0.ResultsThree profiles of self-management behaviors emerged: “Low Self-Management” (50.2%), “High Exercise and Cognitive Management” (8.6%), and “Moderate Management with Enhanced Communication” (41.2%). …”
Get full text

Toxicokinetics and tissue dynamics approaches to evaluate the accumulation and elimination of cadmium in black soldier fly larvae by Jie Zhang, Xuelian Xu, Chunyan Tang, Zhihui Shi, Yujia Wan, Huan Qiu, Rui Feng, Fengfeng Li, Fen Zhu

“…Our research focused on the toxicokinetic and the dynamic tissue changes of cadmium (Cd) in BSFL exposed to low (50 mg/kg), moderate (300 mg/kg), and high levels (700 mg/kg) of Cd stress, with the goal of offering a novel perspective on this matter. …”
Get full text

Effect of Therapeutic Inhibition of TNF on Circulating Endothelial Progenitor Cells in Patients with Rheumatoid Arthritis by F. R. Spinelli, A. Metere, C. Barbati, M. Pierdominici, C. Iannuccelli, B. Lucchino, F. Ciciarello, L. Agati, G. Valesini, M. Di Franco

“…Seventeen patients with moderate-severe RA and 12 sex and age-matched controls were evaluated. …”
Get full text