Efficacy and retention rate of secukinumab in psoriatic arthritis across different clinical phenotypes: insights from the Italian GISEA Registry by Giuseppe Lopalco, Maria Morrone, Fabiola Atzeni, Chiara Bazzani, Francesco Paolo Bianchi, Francesco Paolo Cantatore, Roberto Caporali, Antonio Carletto, Alberto Cauli, Maria Sole Chimenti, Sergio Colella, Fabrizio Conti, Addolorata Corrado, Ennio Giulio Favalli, Alberto Floris, Marco Fornaro, Rosario Foti, Roberta Foti, Elena Fracassi, Bruno Frediani, Stefano Gentileschi, Roberto Gorla, Elisa Gremese, Emanuela Praino, Roberta Ramonda, Cinzia Rotondo, Marco Sebastiani, Angelo Semeraro, Gianfranco Ferraccioli, Giovanni Lapadula, Florenzo Iannone

“…Objectives: To assess the effectiveness of SECU by evaluating drug survival and identifying potential predictors of clinical response and treatment discontinuation in patients with moderate-to-severe PsA, using real-world data from the Italian Group for the Study of Early Arthritis (GISEA) registry. …”
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Clinical Outcomes and Patterns of Traumatic Injuries Associated with Subway Incidents at a Level 1 Trauma Center by Bharti Sharma, Aubrey May B. Agcon, George Agriantonis, Sittha Cheerasarn, Navin D. Bhatia, Zahra Shafaee, Jennifer Whittington, Kate Twelker

“…ISSs for severe injuries (17–24) comprised 9.2%, moderate injuries (10–16) comprised 17.5%, and minor injuries (1–9) comprised 60.8%. …”
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The role of partial splenic artery embolization in the management of refractory esophageal variceal bleeding due to portal vein thrombosis by Büşra Tetik Dinçer, Nafiye Urgancı, Aylin Hasanefendioğlu Bayrak, Özlem Durmaz, İlgin Özden

“…The general condition was moderate, and the skin appeared pale. The liver was palpable 2 cm, and the spleen was palpable 6 cm below the costal margin. …”
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Understanding crystallinity indexes benchmarking concept from optimized parametric ionic liquid pretreatment using 1-ethyl-3-methylimidazolium Acetate [EMIM]Ac on oil palm biomass by Amizon Azizan, Rosmaria Abu Darim, Intan Suhada Azmi, Rafidah Jalil, Shareena Fairuz Abdul Manaf

“…The optimized pretreatment strategy indicated a moderate balance between ionic liquid concentration percentage and operating temperature on a solid loading per volume basis. …”
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Gambaran Klinis dan Endoskopi Saluran Cerna Bagian Atas Pasien Dispepsia di Bagian RSUP Dr. M. Djamil Padang by Citra Yuriana Putri, Arnelis ., Asterina .

“…The results showed that the majority of dyspepsia patients’ complaints were heartburn (98.15%), the degree of complains is moderate (38.89%), the incidence of alarm sign most experienced by male, the most  risk factor of dyspepsia was the consumption of fatty foods (92.59%), the most endoscopic diagnosis of dyspepsia was gastritis (61.11%), and the most upper gastrointestinal lesion of dyspepsia was located in gastric (85.19%)</em><em></em></p><strong><em>Keywords: </em></strong><em>dyspepsia, clinical findings, endoscopy</em>…”
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Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson’s Disease: A Pilot Randomized Controlled Trial by Hanna Johansson, Malin Freidle, Urban Ekman, Ellika Schalling, Breiffni Leavy, Per Svenningsson, Maria Hagströmer, Erika Franzén

“…Participants with mild-to-moderate Parkinson’s disease (PD) were recruited via advertisement. …”
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Multisensor Data Fusion and GIS-DRASTIC Integration for Groundwater Vulnerability Assessment With Rainfall Consideration by Wu Jiazhe, Dai Xinrui, Su Yancheng, Zheng Xiangtian, Bushra Ghaffar, Rabiya Nasir, Ahsan Jamil, Zeeshan Zafar, Mohammad Suhail Meer, M. Abdullah-Al-Wadud, Rahila Naseer, Hesham El-Askary

“…The index map (ranging from 220 to 1980) was further classified into five classes based on index vulnerability: very low (220&#x2013;345), low (346&#x2013;670), moderate (671&#x2013;730), high (731&#x2013;1239), and very high (1240&#x2013;1980). …”
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Clinical course of spinal pain in adolescents: a feasibility study in a chiropractic setting by Steven J Kamper, Christopher G Maher, Mark J Hancock, Simon D French, Lise Hestbæk, Katherine A Pohlman, Michael S Swain, Laura RC Montgomery, Anika Young, Amber Beynon

“…Design Prospective feasibility study.Objectives To inform the design and conduct of a large-scale clinical cohort study investigating adolescents with moderate-to-severe spinal pain.Setting Chiropractic care in Sydney, Australia.Participants Adolescents aged 12–17 years with spinal pain (≥4/10 pain intensity score).Methods Adolescents and chiropractors completed baseline and week-12 follow-up questionnaires, with adolescents reporting pain intensity and recovery weekly via text messages during weeks 1–11. …”
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Sex differences in cardiorespiratory control under hypoxia: the roles of oxygen desaturation and hypoxic exposure time by André Luiz Musmanno Branco Oliveira, Gabriel Dias Rodrigues, Gabriel Dias Rodrigues, Bruno Moreira Silva, Philippe de Azeredo Rohan, Pedro Paulo da Silva Soares

“…Therefore, sex might moderate cardiorespiratory responses to acute hypoxia exposure. …”
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New Benzoxazole Derivatives as Antiprotozoal Agents: In Silico Studies, Synthesis, and Biological Evaluation by Mohamed A. Abdelgawad, Mohammad M. Al-Sanea, Mohamed A. Zaki, Enas I. A. Mohamed, Shabana I. Khan, Babu L. Tekwani, Amar G Chittiboyina, Ikhlas A Khan, Tarfah Al-Warhi, Nada Aljaeed, Ohoud J. Alotaibi, Abdulsalam A. M. Alkhaldi, Heba A. H. Elshemy

“…The amidation of 3-benzoxazolyl aniline 1 with the chloroacetyl functional group resulted in a good antimalarial activity and showed moderate inhibitory activities against leishmanial and trypanosomal spp. …”
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Analyzing Gait Dynamics and Recovery Trajectory in Lower Extremity Fractures Using Linear Mixed Models and Gait Analysis Variables by Mostafa Rezapour, Rachel B. Seymour, Suman Medda, Stephen H. Sims, Madhav A. Karunakar, Nahir Habet, Metin Nafi Gurcan

“…Femur fractures showed moderate readmission and infection rates, indicating a mixed risk profile. …”
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Gambaran Tingkat Depresi pada Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis di RSUP DR. M. Djamil Padang by Fitri Amalia, Nadjmir ., Syaiful Azmi Azmi

“…From this study, a 9 respondents (56.25%) did not experience depression, 6 respondents (37.50%) mild depression and 1 respondent (6.25%) moderate depression. It can be concluded highest rates of depression in patients with chronic kidney disease undergoing hemodialysis at RSUP DR. …”
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A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study by Rong Lin, Yuanjiao Yan, Zhili Chen, Chenshan Huang, Junyu Zhao, Mingfeng Chen, Hong Li

“…Regarding cognitive function, Mini-Mental State Examination scores were significantly improved post-intervention, with a moderate effect size (Hedges’ g = 0.60). Conclusions These findings suggest that MLIP-CE, which was designed based on a theoretical framework, has potential for implementation, and support ongoing research into use of MLIP-CE for individuals at high risk of SCD or other dementia conditions. …”
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Palliative care needs and quality of life among adults with advanced chronic illnesses in low-income communities of Bangladesh by Ahmed Hossain, Maruf Hasan, Taifur Rahman, Alounoud Almarzooqi, Syed Azizur Rahman, Heba Hijazi, Mohamad Alameddine

“…Patients with severe functional limitations (ECOG 3–4) were significantly more likely to need PC (58%) compared to those with moderate or no limitations (ECOG 0–2) (24%). Among those requiring PC, 70.1% rated their QOL as poor or very-poor, while only 23.8% of patients not needing PC reported similar ratings. …”
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Investigation of Potential Profiles and Influencing Factors of Voice Behavior among Chinese Nurses by Shuangying Huang, Hanwen Chen, Liyan Zhang, Xianming Weng, Lingming Zhou, Xiaoqin Ma, Weiyi Wang

“…Conclusion The voice behavior of nurses in China exhibits a moderate level. Heterogeneity was observed in the voice behavior of nurses, suggesting variations among individuals. …”
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Hubungan Jumlah Komplikasi Kronik Dengan Derajat Gejala Depresi Pada Pasien Diabetes Melitus Tipe 2 Di Poliklinik Rsup Dr. M. Djamil Padang by Try Rahmi Lussii Karsuita, Eva Decroli, Delmi Sulastri

“…The amount of normal or minimal depression was 64.5%, mild depression is 27.6 %, and 7.9% for moderate depression. Depression symptoms on the respondents that having one complication is 6.9%, 42.4% for two complications, 88%  for three complications and 60% for four complications. …”
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Beyond borders: investigating the impact of the 2023 conflict in Gaza on generalized anxiety disorders and associated somatic symptoms and wellbeing among the Kuwait population: a... by Musaed Z. Alnaser, Hamad Alhamad, Naser Alotaibi, Nadia Alhamdan, Fahad Manee

“…GAD-7 and mPHQ-5 final scores were moderate (μ = 10.20 ± 4.48; μ = 11.12 ± 6.39), and WHO-5 final score was fair (μ = 53.35 ± 21.82). …”
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Efficacy Study of Carrageenan as an Alternative Infused Material (Filler) in Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Porous 3D Scaffold by Nor Syamimi Che Johari, Syazwan Aizad, Saiful Irwan Zubairi

“…The 3D infused scaffold of 4% (w/v) carrageenan concentration (S2) produced a moderate degradation rate of 0.02±1.55 (mg/day) with a sustained structural integrity up to 28 days. …”
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Exploring the Prognostic Role of Trop-2, CD47, and CD163 Expression Levels on Survival Outcomes in Patients with Triple-Negative Breast Cancer by Ramazan Oguz Yüceer, Sedanur Aydın, Iclal Gelir, Tulay Koc, Ersin Tuncer, Mahmut Ucar

“…High CD47 expression (44.6%) was correlated with advanced stage (<i>p</i> = 0.044), whereas high CD163 expression (45.7%) was associated with advanced stage (<i>p</i> = 0.021), absence of comorbidities (<i>p</i> = 0.022), and lower pT stage (<i>p</i> = 0.023). Moderate positive correlations were found between Trop-2 and CD47 (<i>p</i> = 0.022), Trop-2 and CD163 (<i>p</i> = 0.037), and CD47 and CD163 (<i>p</i> < 0.001), respectively. …”
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Neural activity responsiveness by maturation of inhibition underlying critical period plasticity by Ibuki Matsumoto, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Takashi Kanamaru, Takashi Kanamaru, Yusuke Sakemi, Yusuke Sakemi, Nina Sviridova, Nina Sviridova, Tomoki Kurikawa, Nobuhiko Wagatsuma, Kazuyuki Aihara, Kazuyuki Aihara

“…Additionally, the peak of this profile was consistent with the moderate suppression of the gamma-band spontaneous activity.DiscussionThis finding suggests that the neuronal population's highly reproducible response to increased inhibition may lead to heightened synaptic plasticity. …”
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