Non-Anatomic Reconstruction in Multiligament Knee Injuries: A Functional Approach by Mihai Hurmuz, Cătălin-Adrian Miu, Daniel Ceachir, Romulus-Fabian Tatu, Mihai Andrei, Bogdan Andor, Alexandru Catalin Motofelea, Călin Tudor Hozan

“…While anatomic ligament reconstruction has been traditionally advocated, non-anatomic techniques may provide effective alternatives, particularly for patients with moderate functional demands who do not require high-level athletic performance. …”
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The Effectiveness and Safety of Mesenchymal Stem Cells in the Treatment of Osteoarthritis: A Systematic Review and Meta-analysis of 28 Randomized Controlled Trials by Zhiyong Long, Mingsheng Zhang, Tianqing Zhang, Liuting Zeng, Kailin Yang, Tiejun Yang, Ganpeng Yu, Jun Li, Yang Wu, Hua Chen

“…The quality of WOMAC physical function and adverse events were moderate. Conclusion. Based on current evidence, MSCs may be a safety therapy that have a good curative effect in the treatment of OA, the onset time is no later than 3 months, and the time to maintain the curative effect is no less than 12 months. …”
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Computational and experimental exploration of morpholine pendent 2-hydrazineyl thiazole: Insights from DFT, ADME profiling, antifungal efficacy and molecular docking analyses by Vishnu A. Adole, I.Antony Danish, J.Jebasingh Kores, J.Winfred Jebaraj, S. Janani, Suresh K. Ghotekar, Rakesh D. Amrutkar

“…An energy gap (ΔE) of 2.92 eV was found by the FMO analysis, indicating a moderate degree of stability and chemical reactivity. …”
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The Impact of Lockdown on Air Quality in Pakistan during the COVID-19 Pandemic Inferred from the Multi-sensor Remote Sensed Data by Rehana Khan, Kanike Raghavendra Kumar, Tianliang Zhao

“…We focused on assessing the significant changes of pollutant concentrations during March–May for the years 2019 and 2020 utilizing the satellite datasets observed from the Moderate Resolution Imaging Spectroradiometer (MODIS), Ozone Monitoring Instrument (OMI), Atmospheric Infrared Sounder (AIRS), and Modern-Era Retrospective analysis for Research and Applications (MERRA-2) reanalysis data. …”
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Effects of a 16-week dance intervention on loneliness and self-esteem in left behind children: a randomised controlled trial by Xiaolin Li, Qian Yang, Jiayi Long, Linghui Zhou, Chunxia Lu, Zhenqian Zhou, Ming Zeng, Weixin Dong

“…The Experimental group performed 45 min of moderate-intensity dance training five times a week. …”
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Optimal Timing and Treatment Modalities of Arytenoid Dislocation and Subluxation: A Meta-Analysis by Andrea Frosolini, Valeria Caragli, Giulio Badin, Leonardo Franz, Patrizia Bartolotta, Andrea Lovato, Luca Vedovelli, Elisabetta Genovese, Cosimo de Filippis, Gino Marioni

“…<i>Conclusions</i>: The absence of randomized controlled trials and the overall moderate-to-low quality of the studies highlighted the importance of the finding’s careful interpretation. …”
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Prevalence, Causes, and Risk Factors of Visual Impairment in Emiratis and Non-Emiratis of Dubai: A Subnational Population-Based Cross-Sectional Survey by Manal O. Taryam, M. Mansur Rabiu, Shurooq AlBanna, Noora Al Shamsi, Bushra Albastaki, Hayat Khan, Salam Chettiankandi, Wafa Khamis Alnakhi, Hamid Y. Hussain, Prasan Rao, Gurdeep Singh, Sivakami Pai, Mazen M. Sinjab, Lama Toufik Sharbek, Xianwen Shang, Mingguang He

“…Prevalence of presenting mild, moderate, and severe VI was 4.7% (2.94–7.11%), 1.8% (0.78–3.5%), and 0% for Emiratis, and 3.6% (2.06–5.76), 1.6% (0.63–3.21), and 0% for non-Emiratis, respectively. …”
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Effect of Dry Aging on Beef Muscle Proteins by Galina V. Gurinovich, Irina S. Patrakova, Vladislav A. Khrenov, Marina V. Patshina, Antonina I. Shevchenko

“…According to the amino acid analysis, the optimal result was most pronounced on day 42 as proven by the moderate oxidative changes in proteins.…”
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Association of Wrist Circumference and Waist-to-Height Ratio with Cardiometabolic Risk Factors among Type II Diabetics in a Ghanaian Population by Christian Obirikorang, Yaa Obirikorang, Emmanuel Acheampong, Enoch Odame Anto, Emmanuel Toboh, Evans Adu Asamoah, Bright Amakwaa, Emmanuella Nsenbah Batu, Peter Brenya

“…WrC [aOR = 6.13 (0.34–111.4), p=0.107] and WHtR [aOR = 2.52 (0.42–15.02), p=0.309] were associated with statistically insignificant increased odds of moderate-to-high risk of developing CVDs in 10 years. …”
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Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis by Cristina Gonzalez-Martin, Silvia Grande Morais, Sonia Pertega-Diaz, Teresa Seoane-Pillado, Vanesa Balboa-Barreiro, Raquel Veiga-Seijo

“…The prevalence of patients with moderate/high cardiovascular risk varies according to the score used, the levels of concordance being the scores of Framingham and Dorica.…”
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Geological characteristics and main enrichment controlling factors of coalbed methane in Nanchuan area, southeastern Sichuan Basin by Xipeng HE, Kaiming WANG, Wei LUO, Yuqiao GAO, Nana LIU, Tao GUO, Yatong ZHOU, Didi WU

“…It is characterized by "high gas content, abundant free gas, and oversaturation", and its gas content increases with burial depth. (4) The in-situ stress in the study area is moderate (35 to 60 MPa), with a small two-way horizontal stress difference coefficient (< 0.1) and good roof and floor plates, forming effective stress shielding favorable for fracturing transformation. (5) The main controlling factors for CBM methane enrichment in the Nanchuan area include the sedimentary environment, which determines coal-bearing formations; the degree of coal evolution, which determines the intensity of hydrocarbon generation; and the preservation conditions, which govern CBM enrichment.…”
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Pharmacological Management of Chronic Neuropathic Pain – Consensus Statement and Guidelines from the Canadian Pain Society by DE Moulin, AJ Clark, I Gilron, MA Ware, CPN Watson, BJ Sessle, T Coderre, PK Morley-Forster, J Stinson, A Boulanger, P Peng, GA Finley, P Taenzer, P Squire, D Dion, A Cholkan, A Gilani, A Gordon, J Henry, R Jovey, M Lynch, A Mailis-Gagnon, A Panju, GB Rollman, A Velly

“…Tramadol and controlled-release opioid analgesics are recommended as third-line treatments for moderate to severe pain. Recommended fourth-line treatments include cannabinoids, methadone and anticonvulsants with lesser evidence of efficacy, such as lamotrigine, topiramate and valproic acid. …”
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Salinity Tolerance of Artificially Restored Vegetation Under Different Irrigation Strategies in Arid, Abandoned Mining Areas by Aishajiang Aili, Yuguang Zhang, Tao Lin, Hailiang Xu, Abdul Waheed, Wanyu Zhao, Jia Wang, Chuhan Wang

“…These findings highlight that drip irrigation, particularly when combined with moderate salinity (8 g/L), is a more effective strategy for enhancing vegetation growth and survival in arid, saline environments. …”
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E-HEART score: A novel scoring system for undifferentiated chest pain in the emergency department by V. Yuvaraj, Sachin Sujir Nayak, S. Vimal Krishnan

“…Eighty-one patients with moderate E-HEART scores (4–6) were found to have 30.9% MACE. …”
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Role of Intraplate Strike-Slip Earthquakes in Accommodating Convergence Across the Eastern Himalayan Plate Boundary System by Dibyajyoti Chaudhuri, Rupak Banerjee, Ajay Kumar, Shubham Sharma, Supriyo Mitra

“…We model the source mechanisms of six recent moderate-to-strong intraplate earthquakes (5.0≤ Mw ≤6.7) using teleseismic P- and SH-waveform inversion and use source directivity and rupture back-projection, for the largest event, to isolate the fault plane. …”
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Relationship Between Sedentary Lifestyle, Physical Activity and Stress in University Students and Their Life Habits: A Scoping Review with PRISMA Checklist (PRISMA-ScR) by Mariasole Antonietta Guerriero, Anna Dipace, Antonietta Monda, Antonella De Maria, Rita Polito, Giovanni Messina, Marcellino Monda, Marilena di Padova, Angelo Basta, Maria Ruberto, Emanuele Capasso, Fiorenzo Moscatelli, Pierpaolo Limone

“…Interventions included yoga, tai chi, aerobic exercise and moderate- or high-intensity exercise. A lack of standardized protocols were also evident. …”
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Predictive value of the New Zealand Early Warning Score for early mortality in low-acuity patients discharged at scene by paramedics: an observational study by Bridget Dicker, Verity Frances Todd, Tony Smith, Andy Swain, Graham Howie, Melanie Moylan, Aroha Brett

“…The best predictability for adverse outcome was observed for 2-day and 7-day mortality, with moderate area under the receiver operating characteristic curve scores of 0.78 (95% CI: 0.73 to 0.82) and 0.74 (95% CI: 0.71 to 0.77), respectively.Conclusions Adverse outcomes in low-acuity non-transported patients show a significant association with risk prediction by the NZEWS. …”
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Vulnerability for alcohol use disorder after adverse childhood experiences (AUDACE): protocol for a longitudinal fMRI study assessing neuropsychobiological risk factors for relapse by Falk Kiefer, Cagdas Türkmen, Noah Machunze, Haoye Tan, Sarah Gerhardt, Sabine Vollstädt-Klein

“…Furthermore, participants with no or mild ACE will be compared with participants with moderate to severe ACE to assess between-subject differences in risk factors for AUD. …”
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Lithium Carbonate in the Treatment of Graves’ Disease with ATD-Induced Hepatic Injury or Leukopenia by Rendong Zheng, Kemian Liu, Kun Chen, Wen Cao, Lin Cao, Huifeng Zhang, Hongping Sun, Chao Liu

“…Lithium carbonate has effects on the treatment of mild-to-moderate hyperthyroidism caused by GD, and it is particularly suitable for patients with ATD-induced hepatic injury or leukopenia.…”
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SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy by Yang Gao, Jing Li, Lin Gan, Meng Cai, Xiaofeng Lei, Jin Yu

“…Results Patients in the AA group had higher scores on the pain Catastrophizing Scale, PSQ-total, PSQ-minor, and PSQ-moderate compared to GA and GG groups (P < 0.05). VAS scores at 4, 6, and 12 h post-operation were higher in the AA group than the GG group (P < 0.05). …”
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