GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…Emerging evidence suggests a strong link between moderate to severe TBI and an elevated risk of PD, though the underlying mechanisms remain poorly understood.Materials and Methods: Common differentially expressed genes (DEGs) were identified in GEO datasets of patients with traumatic brain injury (TBI) and Parkinson’s disease (PD). …”
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Harmony in healthcare: recommended infant feeding practices and associated factors among HIV positive mothers in Eastern Ethiopian hospitals by Muluken Yigezu, Natnael Kebede

“…Conclusion the study identified a moderate level of adherence to recommended infant feeding practices among HIV-positive mothers in Eastern Ethiopian hospitals. …”
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Assessing the clinical support capabilities of ChatGPT 4o and ChatGPT 4o mini in managing lumbar disc herniation by Suning Wang, Ying Wang, Linlin Jiang, Yong Chang, Shiji zhang, Kun Zhao, Lu Chen, Chunzheng Gao

“…The AUC was 0.80, and the Kappa value was 0.61, indicating moderate agreement between the model’s predictions and actual diagnoses, though with room for improvement. …”
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Pre- and Post-Operative Pain Intensity and Physical Activity Levels in Individuals with Acetabular Dysplasia Undergoing Periacetabular Osteotomy: A Prospective Cohort Study by Naif Alrashdi, Robert Motl, Elroy Aguiar, Donald Lein Jr, Suzanne Perumean-Chaney, Michael Ryan, Matthew Ithurburn

“…PA levels was evaluated before and six months following PAO using accelerometers (time spent in sedentary behavior, light PA, moderate-to-vigorous PA \[MVPA\], and daily steps) and the International Physical Activity Questionnaire (IPAQ; time spent in walking and in MVPA). …”
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Effectiveness of digital behaviour change interventions for promoting physical activity in adolescents with overweight and obesity: A systematic review and meta-analysis by Puteri Shanaz Jahn Kassim, Noor Azimah Muhammad, Nur Faraheen Abdul Rahman, Sherina Mohd Sidik, Cecilia A. Essau, Shamsul Azhar Shah

“…DBCIs showed a large, significant positive effect on total physical activity (SMD = 1.61, 95% CI: [0.56, 2.66], p  = 0.003), but non-significant effects on moderate-to-vigorous physical activity (MVPA) (SMD = 0.16, 95% CI: [−0.39, 0.71], p  = 0.56) and step count (SMD = −0.10, 95% CI: [−0.52, 0.32], p  = 0.65). …”
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A New Approach to Identifying Red Supergiant Stars in Metal-poor Galaxies: A Case Study of NGC 6822 by Zhi-wen Li, Ming Yang, Biwei Jiang, Yi Ren

“…The metal-poor galaxy NGC 6822 is taken as a case study for its low metallicity ([Fe/H] ≈ −1.0) and moderate distance (about 500 kpc). In the complete sample, we identify 1184 RSG, 1559 oxygen-rich AGB (O-AGBs), 1075 carbon-rich AGB (C-AGBs), and 140 extreme AGB (x-AGBs) candidates, with a contamination rate of approximately 20.5%, 9.7%, 6.8%, and 5.0%, respectively. …”
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Distance Learning For Military Doctors in Crisis Situations: The DILEMMA Cross-Sectional Study Results by Nataliia Sydorova, Valerii Savytskyi, Taras Kuts

“…The overall evaluations of distance learning as measured by a 10-point scale (primary endpoint) were 5.9±3.3 for DILEMMA-1 and 6.5±3.3 for DILEMMA-2 (p=0.27), which indicates a moderate overall evaluation. The proportion of satisfied and very satisfied students was smaller in the DILEMMA-1 group compared to DILEMMA-2 but remained quite high (76.9% vs. 92.8%, respectively, p<0.05). …”
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Decrease in HBsAg After TAF Switching from Entecavir During Long-Term Treatment of Chronic Hepatitis B Virus Infection by Kazuto Tajiri, Yuka Hayashi, Aiko Murayama, Nozomu Muraishi, Masami Minemura, Ichiro Yasuda

“…This finding suggests patients with mild to moderate fibrosis may respond better to TAF in terms of HBsAg reduction.…”
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NSAID-Induced Enteropathy in Rheumatoid Arthritis Patients with Chronic Occult Gastrointestinal Bleeding: A Prospective Capsule Endoscopy Study by Ilja Tachecí, Petr Bradna, Tomáš Douda, Drahomíra Baštecká, Marcela Kopáčová, Stanislav Rejchrt, Jan Bureš

“…The prevalence of NSAID-induced enteropathy diagnosed by capsule endoscopy was 68% (25/37), classified as mild (red spots or erosions) in 18 (49%), moderate (10–20 erosions) in 4 (11%), and severe enteropathy (>20 erosions or ulcers) in 3 (8%) patients. …”
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Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials by Jianyu Gan, Jiya He, Kaixiang Zhou, Zhangyuting Shang, Gengxin Dong, Dapeng Bao, Junhong Zhou

“…In the meta-regression, moderators such as the mean age, sex, and baseline BDNF levels of participants, as well as total TCEs time were not associated with outcome variables. …”
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Clinical efficacy of 0.1% cyclosporine A in dry eye patients with inadequate responses to 0.05% cyclosporine A: a switching, prospective, open-label, multicenter study by Sook Hyun Yoon, Eun Chul Kim, In-Cheon You, Chul Young Choi, Jae Yong Kim, Jong Suk Song, Joon Young Hyon, Hong Kyun Kim, Kyoung Yul Seo

“…This finding suggests that higher concentrations of CsA may be more effective in treating individuals with moderate to severe DED.…”
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Donor Identification, Genetic Diversity, Population Structure and Marker–Trait Association Analyses for Iron Toxicity Tolerance Using Rice Landraces by Debanjana Saha, Udit Nandan Mishra, Chittaranjan Sahoo, Seema Tripathy, Uttam Kumar Behera, Susmita Das, Chandrasekhar Sahu, Shiv Datt, Manoj Kumar Rout, Tanmaya Lalitendu Mohanty, Shakti Prakash Mohanty, Saumya Ranjan Barik, Ishwar Chandra Mohanty, Sharat Kumar Pradhan

“…The studied population showed a moderate to high degree of genetic diversity, as revealed by the estimated molecular diversity parameters and principal component, cluster and box plot analyses. …”
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Is sleep bruxism associated with smartphone use, neck pain, and sleep features among adolescents? by Ivana Meyer PRADO, Letícia Fernanda MOREIRA-SANTOS, Gabriela de Faria e Barboza HOFFMAM, Lucas Guimarães ABREU, Sheyla Márcia AUAD, Isabela Almeida PORDEUS, Júnia Maria SERRA-NEGRA

“…Adolescents reporting nightmares at least once a month (OR = 3.402; 95%CI: 1.315–8.802) and sometimes experiencing smartphone-induced neck pain (OR: 3.697, 95%CI: 1.103–12.388) were more likely to report moderate/severe grinding. Drooling on the pillow (OR = 3.105, 95%CI: 1.316–7.329), poor/fairly good sleep quality (OR = 2.717, 95%CI: 1.279–5.770), and smartphone-induced neck pain (OR = 3.227, 95%CI: 1.121–9.285) were associated with mild bracing. …”
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Quick sequential organ failure assessment score combined with other sepsis-related risk factors to predict in-hospital mortality: Post-hoc analysis of prospective multicenter study... by Ryo Ueno, Takateru Masubuchi, Atsushi Shiraishi, Satoshi Gando, Toshikazu Abe, Shigeki Kushimoto, Toshihiko Mayumi, Seitaro Fujishima, Akiyoshi Hagiwara, Toru Hifumi, Akira Endo, Takayuki Komatsu, Joji Kotani, Kohji Okamoto, Junichi Sasaki, Yasukazu Shiino, Yutaka Umemura

“…Following prior literature, an AUC >0.9 was deemed to indicate high accuracy; 0.7-0.9, moderate accuracy; 0.5-0.7, low accuracy; and 0.5, a chance result. …”
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Prevalence, Treatment, and Unmet Needs of Migraine in the Middle East: A Systematic Review by Taoufik Alsaadi, AbuBakar Al Madani, Mohammed Alhatou, Mona Nada, Abdulrazaq Albilali, Ahmed Al-Qassabi, Hegab Mohamed, Haytham Mohamed, Rowan El Masry, Ghaidaa Ahmed Saifuddin, Suhail Abdullah AlRukn

“…Abstract Introduction Migraine is a debilitating neurological disorder characterized by recurrent throbbing, moderate-to-severe headaches that disrupt daily chores, leisure, and social activities of patients, impacting their overall quality of life (QoL). …”
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Relationship between White Blood Count to Mean Platelet Volume Ratio and Clinical Outcomes and Severity of Coronary Artery Disease in Patients Undergoing Primary Percutaneous Coron... by Altekin Refik Emre, Kilinc Ali Yasar, Yanikoglu Atakan, Cicekcibasi Orhan, Kucuk Murathan

“…The Kaplan-Meier analysis showed that the high WMR group had the significantly lowest MACE-free survival rate (log-rank test, p=0.006). A moderate correlation was observed between WMR and RSS (r: 456, p=0.002). …”
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Exploring rural households’ knowledge and perception of acute kidney injury in the southern region of The Gambia: a mixed-method community-based cross-sectional study design by Bakary Kinteh, Sheikh Omar Sillah, Solomon P S Jatta, Sambou L S Kinteh, Mansour Badjie, Ebrima Touray, Amadou Barrow

“…Interestingly, 97.1% of the participants held a moderate perception of AKI in The Gambia and firmly rejected the notion that the outbreak was politically motivated. …”
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Research on Traffic Accident Severity Level Prediction Model Based on Improved Machine Learning by Jiming Tang, Yao Huang, Dingli Liu, Liuyuan Xiong, Rongwei Bu

“…In the prediction of different traffic accident severity levels (minor, moderate, and severe), the improved machine learning model also generally shows better performance and stability. …”
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Complex Cloud-Sea Background Simulation for Space-Based Infrared Payload Digital Twin by Wen Sun, Yejin Li, Fenghong Li, Guangsen Liu, Peng Rao

“…Finally, we validate the confidence of the simulated images through morphological assessment using a 2-D histogram and radiative accuracy evaluation based on Moderate resolution atmospheric transmission (MODTRAN) results. …”
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Magnitude of immediate postpartum anaemia and associated factors among mothers at selected public hospitals in North Shoa Zone, Oromia regional state, Ethiopia: a cross-sectional s... by Genanew Nigusu, Negash Wakgari, Mistiwat Abebe, Meseret Moroda

“…Factors significantly associated with immediate postpartum anaemia included postpartum haemorrhage (AOR: 4.95; 95% CI 2.09 to 11.76), history of abortion (AOR: 4.01; 95% CI 1.93 to 8.35), rural residence (AOR: 3.03; 95% CI 1.49 to 6.16), poor adherence to iron and folic acid supplementation (AOR: 2.66; 95% CI 1.27 to 5.58) and midupper arm circumference (MUAC) &lt;23 cm (AOR: 2.19; 95% CI 1.08 to 4.42).Conclusion The magnitude of immediate postpartum anaemia was a moderate public health problem. Factors such as postpartum haemorrhage, history of abortion, rural residence, poor adherence to iron and folic acid supplementation and MUAC &lt;23 cm were significantly associated with immediate postpartum anaemia. …”
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