Lack of reactivation of tuberculosis in patients with psoriasis treated with secukinumab in a real-world setting of latent tuberculosis infection by Matteo Megna, Cataldo Patruno, Maria Rita Bongiorno, Alessio Gambardella, Claudio Guarneri, Caterina Foti, Serena Lembo, Francesco Loconsole, Gabriella Fabbrocini

“…However, there is a low reported incidence of conversion to positive TBC status among patients with psoriasis treated with second-generation biologic therapies, particularly anti-interleukin (IL)-17 therapies such as secukinumab.Objectives To evaluate the safety profile of secukinumab in psoriasis patients with latent TBC infection.Methods Real-life data were collected by retrospective chart review on patients with moderate-to-severe psoriasis who showed positivity for TBC screening at baseline and underwent secukinumab treatment for psoriasis at six Italian centers. …”
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Uptake and safety of Sotrovimab for prevention of severe COVID-19 in a cohort and self-controlled case series study by Martina Patone, Andrew JHL Snelling, Holly Tibble, Carol Coupland, Aziz Sheikh, Julia Hippisley-Cox

“…Trials have shown it to have mild to moderate side effects, however, evidence regarding its safety in real-world settings remains insufficient. …”
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Lifelong cardiovascular care in Turner syndrome: two cases with review of literature by Shun Moriguchi, Yuri Mukoyama, Fumihiko Takizawa, Atsushi Ogawa, Tetsushi Ogawa, Junko Ito, Yukishige Yanagawa, Chinatsu Komiyama, Rieko Niitsu, Tsuyoshi Isojima

“…The second case patient was diagnosed with moderate mitral valve regurgitation (MR) due to mitral valve prolapse at 18 years through TTE, although the first evaluation at 7 years by TTE detected slight MR without any clinical concerns. …”
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Effects of prenatal exercise interventions on maternal body composition: A secondary analysis of the FitMum randomized controlled trial. by Caroline Borup Roland, Parisa Seyedhosseini, Signe de Place Knudsen, Anne Dsane Jessen, Ida Karoline Bach Jensen, Jane M Bendix, Gerrit van Hall, Stig Molsted, Saud Abdulaziz Alomairah, Ellen Løkkegaard, Bente Stallknecht, Tine D Clausen

“…Maternal body composition was measured by doubly labeled water at 28 weeks gestation (n = 134) and by dual-energy X-ray absorptiometry scan 7-14 days after delivery (n = 117). PA, including moderate-to-vigorous-intensity PA (MVPA), active kilocalories, and steps, were measured continuously from inclusion to delivery by a wrist-worn activity tracker. …”
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Validity and Reliability of Upper Limb Functional Assessment Using the Microsoft Kinect V2 Sensor by Laisi Cai, Ye Ma, Shuping Xiong, Yanxin Zhang

“…Kinect V2 had good accuracy in measuring shoulder and elbow flexion/extension angular waveforms (CMC>0.87), moderate accuracy of measuring shoulder adduction/abduction angular waveforms (CMC=0.69-0.82), and poor accuracy of measuring shoulder internal/external angles (CMC<0.6). …”
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Patient‐Reported Fatigue Associated with Joint Histopathology in Rheumatoid Arthritis by Diyu Pearce‐Fisher, Melanie H. Smith, Bella Y. Mehta, Edoardo Spolaore, Edward DiCarlo, Dongmei Sun, Susan M. Goodman

“…Demographics, RA characteristics, tender and swollen joints, erythrocyte sedimentation rate (ESR) and C‐reactive protein, and patient‐reported fatigue, categorized as mild, moderate, or severe, were collected. Hematoxylin and eosin stains of sectioned synovium were systematically scored by a pathologist. …”
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Risk-Stratified Cardiovascular Screening Including Angiographic and Procedural Outcomes of Percutaneous Coronary Interventions in Renal Transplant Candidates by Julian König, Martin Möckel, Eda Mueller, Wolfgang Bocksch, Seema Baid-Agrawal, Nina Babel, Ralf Schindler, Petra Reinke, Peter Nickel

“…In high risk patients, cardiac screening did not improve outcome as 21.7% of patients with versus 15.5% of patients without properly performed cardiac screening had MACE (P=0.319). Conclusion. The moderate procedural success of PCI and poor outcome in long and diffuse coronary lesions underscore the need to define appropriate revascularization strategies in KTC, which will be a prerequisite for cardiac screening to improve outcome in these high-risk patients.…”
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APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease by Marta Moreno-Rodriguez, Sylvia E. Perez, Michael Malek-Ahmadi, Elliott J. Mufson

“…To evaluate the effects of APOEε4 on ApoE, Fabp7 and myelin in the WM of the frontal cortex (FC), we examined individuals carrying one ε4 allele that came to autopsy with a premortem clinical diagnosis of no cognitive impairment (NCI), mild cognitive impairment (MCI) and mild to moderate AD compared with non-carrier counterparts. …”
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Effects of Vitamin C on Growth and Non-Specific Immune Response of Labeo gonius Fry in Density-Dependent Biofloc Rearing by Ng Chinglembi Devi, Gusheinzed Waikhom, Soibam Khogen Singh, Pronob Das, Sourabh Debbarma, Reshmi Debbarma, Lukram Sushil Singh, Martina Meinam, Pradyut Biswas, Surajkumar Irungbam

“…A better feed conversion ratio and significantly higher protein efficiency ratio were found in the moderate stocking density group (10 fish per 50 L) fed with 500 mg kg−1 Vit C. …”
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First Comprehensive List of Phlebotomine Sand Fly Species (Diptera: Psychodidae) in a Leishmaniasis Focus (Djelfa, Algeria), Including the First Record of Phlebotomus langeroni Fem... by Fatma Messaoudene, Slimane Boukraa, Said Chaouki Boubidi, Ahlem Guerzou

“…Considering the other factors, there was a moderate link between species richness and altitude (p= 0.01 R2= 0.519). …”
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Digitally assessing social–emotional skills in early school years: initial validation of a screening instrument by Andrea Kogler, Andrea Kogler, Barbara Gasteiger-Klicpera, Barbara Gasteiger-Klicpera, Katharina Prinz, Lisa Paleczek, Lisa Paleczek

“…The validity check revealed low to moderate correlations between teacher rating and student scores. …”
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Transgenerational epigenetic heritability for growth, body composition, and reproductive traits in Landrace pigs by Andre C. Araujo, Jay S. Johnson, Jason R. Graham, Jeremy Howard, Yijian Huang, Hinayah R. Oliveira, Luiz F. Brito

“…Transgenerational epigenetic heritability estimates are moderate for growth and body composition and low for reproductive traits in North American Landrace pigs. …”
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Metallized Sol–Gel coatings on ceramic glazes with photocatalytic activity by Guillermo Monrós, Carolina Delgado, José Antonio Badenes, Guillem Monrós-Andreu, Mario Llusar

“…Fe2O3 coatings show moderate photocatalytic activity, with a half-life period of 146 minutes for the optimal sample.…”
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ASSOCIATION BETWEEN SENSORIAL OTOLITHIC DEFICIT AND HEARING LOSS IN CHILDREN by Constantin Guma, Cristian Marius Mârțu, Sebastian Cozma, Raluca Olariu, Luminița Rădulescu, Alexandru Stingheriu, Iustin Iațentiuc, Mădălina Georgescu, Violeta Necula, Oana Bitere-Popa

“…The otolithic function impairment was proportional to the severity of hearing loss: in the moderate hearing loss group, it was present in 36,36% of both the saccular and utricular functions, in the severe hearing loss group it was found in 36,67% of ears for the utricular function and 23,33% for the saccular function. …”
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Exploring the hidden synergy between system thinking and patient safety competencies among critical care nurses: a cross-sectional study by Amal Diab Ghanem Atalla, Rwan Ragab Rabea Bahr, Ahmed Abdelwahab Ibrahim El-Sayed

“…Results Nurses demonstrated moderate to high levels of systems thinking (mean = 82.36 ± 12.14) and patient safety competencies (mean = 162.74 ± 23.56). …”
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In-Situ Polymerization for Catalytic Graphitization of Boronated PAN Using Aluminum and Zirconium Containing Co-Catalysts by Taewoo Kim, Byoung-Suhk Kim, Tae Hoon Ko, Hak Yong Kim

“…The addition of external catalysts during in-situ polymerization not only enhances the polymerization rate but also facilitates the degree of graphitization and quality of graphitic carbon upon graphitization at moderate temperatures. In this study, we apply an in-situ polymerization technique to integrate aluminum triflate (Al(OTf)₃) and zirconocene dichloride (C₅H₅)₂ZrCl₂ co-catalyst into a boronated polyacrylonitrile (B-PAN) matrix. …”
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Control of White Spot Lesion Adjacent to Orthodontic Bracket with Use of Fluoride Varnish or Chlorhexidine Gel by Manuel Restrepo, Diego G. Bussaneli, Fabiano Jeremias, Rita C. L. Cordeiro, Ana C. Magalhães, Denise M. Palomari Spolidorio, Lourdes Santos-Pinto

“…The correlation between QLF and TMR was significantly moderate. Two applications of fluoride varnish or 2% chlorhexidine gel at one-week intervals were effective in controlling WSLs.…”
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Evaluation of terminal blend rubberized asphalt incorporating high crumb rubber content by Yangquan Huang, Kun Long, Chi Qu, Chuanqi Yan, Changfa Ai, Shengxiong Zhou

“…However, while TBRA shows excellent low-temperature performance and fatigue resistance, its high-temperature properties are moderate, suggesting further modifications with materials like SBS or rock asphalt could enhance its performance.…”
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Solvent-free valorization of sugarcane bagasse fibers into nitrogen-doped microporous carbons: Efficient contenders for selective carbon dioxide capture by Urooj Kamran, Nasir Shezad, Soo-Jin Park, Kyong Yop Rhee, Shujie You, Farid Akhtar

“…The optimized material exhibited a moderate isosteric heat of adsorption and an effective CO₂/N₂ selectivity at 293 K. …”
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Poor Nurses’ Work Environment Increases Quiet Quitting and Reduces Work Engagement: A Cross-Sectional Study in Greece by Ioannis Moisoglou, Aglaia Katsiroumpa, Aggeliki Katsapi, Olympia Konstantakopoulou, Petros Galanis

“…<b>Conclusions:</b> Our findings highlight the poor work environment, elevated levels of quiet quitting, and moderate work engagement among nurses. Moreover, we found that a poor nurses’ work environment was associated with higher levels of quiet quitting. …”
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