Fast Atomic Charge Calculation for Implementation into a Polarizable Force Field and Application to an Ion Channel Protein by Raiker Witter, Margit Möllhoff, Frank-Thomas Koch, Ulrich Sternberg

“…Our calculations show that moderate changes of side chain torsion angle χ1 and small variations of χ2 of Trp-41 are necessary to switch from the inactivated into the activated state; and a rough two-side jump model of His-37 is supported for proton gating in accordance with a flipping mechanism.…”
Get full text

Gambaran Tingkat Kepatuhan Pengobatan Pasien TB Paru by Endang Martini, Rika Sarfika, Siti Yuliharni

“…Of the total respondents, 51% showed low adherence, 29% moderate adherence, and 20% high adherence. Demographic characteristics revealed that the majority of respondents were male (64.7%), with the largest age group being pre-elderly (42.7%). …”
Get full text

Prevalence of Primary Dysmenorrhoea and Its Impact on Academic Performance among Croatian Students during the COVID-19 Pandemic by Marta Horvat, Doroteja Pavan Jukić, Lovro Marinović, Dina Bursać, Rosana Ribić, Marijana Neuberg, Danijel Bursać

“…Menstrual pain was mild in 7.4% of cases, moderate in 28.8%, and severe in 63.8%. The study found that primary dysmenorrhoea has a great perceived impact on all included aspects of academic performance. …”
Get full text

Analysis of a Flux-Concentrated V-Type Biased-Flux Slot Motor by Mohammad Amirkhani, Ehsan Farmahini Farahani, Mohammad Afrank, Mojtaba Mirsalim, Nick J. Baker

“…By switching from the more usual circumferential magnets, it has been shown that torque production per unit magnet mass can increase by over 20% for a moderate 0.5% increase in torque ripple. This is by virtue of the significant increase in flux concentration in the air gap, which is proven mathematically, via simulation and validated experimentally. …”
Get full text

Shoreline Stability Analysis At Merah Putih Beach, Bangkalan Regency by Dyah Ambarwati Rieke, Dwi Siswanto Aries

“…According to the classification of the coastline in DSAS statistics, the two segments with a value of 0.511 meters / year and -0.768 meters / year are included in the moderate abrasion category. So that the beach during the 12-year period experienced a stable condition with a significant beach dynamics profile.…”
Get full text

Screening for anxiety in patients with cancer: Diagnostic accuracy of GAD-7 items considering lowered GAD-7 cut-offs. by Miriam Grapp, Till J Bugaj, Valentin Terhoeven, Hans-Christoph Friederich, Imad Maatouk

“…The cognitive items had the best diagnostic accuracy for identifying severe GAD (cut-off ≥ 15), and the somatic-emotional items had the best diagnostic accuracy for identifying mild to moderate GAD (cut-off ≥ 7, ≥ 8 and ≥ 10).<h4>Conclusions</h4>Our data support the recommendation of lowering the GAD-7 cut-off in oncology settings and suggest that in anxiety disorders, a symptom overlap between the physical illness and a possible mental disorder should be considered.…”
Get full text

Monitoring Driving in a Monotonous Environment: Classification and Recognition of Driving Fatigue Based on Long Short-Term Memory Network by Hao Han, Kejie Li, Yi Li

“…The recognition rate of the established fatigue degree recognition model for driver’s awake state, mild fatigue, moderate fatigue, and severe fatigue is 100%, 93.1%, 98.4%, and 100% respectively, and the total recognition rate can reach 97.8%, which is higher than the recognition accuracy of the traditional machine learning approach.…”
Get full text

Effects of Grazing Intensity on Microbial Diversity at Different Soil Depths in Desert Steppe Soils by Yuxin Wang, Xin Ju, Qian Wu, Guodong Han

“…Soil samples were collected from three depths (0–10 cm, 10–20 cm, and 20–30 cm) under varying grazing intensities: control (CK), light (LG), moderate (MG), and heavy grazing (HG). Key soil physicochemical properties and plant characteristics were analyzed alongside microbial diversity and community composition, which were assessed by identifying amplicon sequence variants and by conducting linear discriminant analysis effect size. …”
Get full text

Sensory Behaviours and Resting Parasympathetic Functions among Children with and without ADHD by Ivan Neil Gomez, Lissa Martha Domondon, Hector WH Tsang, Chetwyn CH Chan, Cynthia YY Lai

“…Likewise, a significant moderate positive correlation (r = 0.36, p<0.05) was found between the HF n.u. and sensory profile total scores among children with ADHD. …”
Get full text

Rosacea-like skin reaction under treatment with dupilumab for atopic dermatitis by C. Grote, F. Zirkenbach, J. N. Wagner, M. Augustin

“…Purpose Dupilumab is a widely recommended treatment for moderate-to-severe atopic dermatitis (AD), with known ocular side effects but less frequent cutaneous reactions.Material and methods This case report details a 52-year-old female patient with atopic dermatitis treated with dupilumab. …”
Get full text

Cohort profile: prevalence of valvular heart disease in community patients with suspected heart failure in UK by Rajan Sharma, Anna Marciniak, Keli Glover

“…All patients underwent a standard transthoracic echocardiogram according to British Society of Echocardiography guidelines.Findings to date Of the total number, 29 682 patients (37.5%) were diagnosed with mild valve disease, 8983 patients (11.3%) had moderate valve disease and 2134 (2.7%) had severe valve disease. …”
Get full text

Physiotherapy under pressure: A cross-sectional study on the interplay between perfectionism, moral injury, and burnout. by Daniel Biggs, Laura Blackburn, Cameron Black, Sivaramkumar Shanmugam

“…<h4>Findings</h4>Our analysis conducted on (n = 402) UK-based physiotherapists reveals significant burnout levels, with 96% of participants presenting with moderate to high burnout scores. SEM revealed perfectionism and moral injury collectively accounted for a substantial 62% of burnout variability, highlighting their sequential impact on burnout manifestation.…”
Get full text

Case Report: Major right-sided hepatectomies in infants in Uzbekistan: a case series by K. Semash, T. Dzhanbekov, S. Islomov

“…Postoperative complications were minimal, with two cases of mild to moderate post-hepatectomy liver insufficiency (Clavien-Dindo grades 1–2) and one bile leak (Clavien-Dindo grade 2) that resolved spontaneously. …”
Get full text

Review of Life-Cycle Approaches Coupled with Data Envelopment Analysis: Launching the CFP + DEA Method for Energy Policy Making by Ian Vázquez-Rowe, Diego Iribarren

“…The fact that this method relies on the definition of operating points with optimised resource intensity helps to moderate the concerns about the omission of other environmental impacts. …”
Get full text

Regional Climate Model Sensitivity to Domain Size for the Simulation of the West African Summer Monsoon Rainfall by Nana A. K. Browne, Mouhamadou B. Sylla

“…The best performance is, however, captured in the RegCM-D3 experiment, and this originates from a simulation of moderate westerly moisture fluxes along with a stronger AEJ and occurrences of more frequent African Easterly Waves (AEWs). …”
Get full text

Association Between Hopelessness And Suicidal Ideation In Iranian Medical Students: A Cross-Sectional Study by Mohammad Hossein Sadeghian, Farnaz Etesam, Amin Nakhostin-Ansari, Samaneh Akbarpour, Mitra Akhlaghi

“…One hundred seven students (47.76%) had mild, 58 (25.89%) had moderate, and 13 (5.8%) had severe hopelessness. Males, senior students, and dissatisfied students with their academic performance experienced more severe hopelessness (P\<0.05). …”
Get full text

An analysis of the quality of educational services provided for rural administrators (A case study of Dehyars in Nasrabad District, Torbat Jam County) by hamdolah sojasi qedari, hamide mahmoodi, mahboobe shirmohamadi

“…The results of single sample t-test indicate that the mean of respondents' views in two dimensions of perceptions and expectations from training services is moderate to high. Further, according to the gap analysis (using the SERVQUAL model), in all aspects of the quality of training services, there is a negative gap between the perceptions and expectations of the Dehyars from training services. …”
Get full text

The Impact of Artificial Intelligence Applications on Digital Banking in Turkish Banking Industry by Serkan Demirel, Murat Topcu

“…In addition, there is a close correlation between mobile banking and the independent variable chat box, no correlation between mobile banking and video calling, and a moderate correlation between chat box and video calling. …”
Get full text

Alterations in Parafoveal and Optic Disc Vessel Densities in Patients with Obstructive Sleep Apnea Syndrome by Turgay Ucak, Ethem Unver

“…Of the OSAS patients, 27 had mild, 24 had moderate, and 26 had severe disease. The intraocular pressure (IOP) values were significantly higher in the severe OSAS group than the control cases (p=0.001). …”
Get full text

An Analysis of Spatial Pathology of the Physical and Social Structure of the City with Non-Relevant Defense Approach Case Study: Tehran Metropolitan Area by s z, a t, m a

“…The results of this study indicate that the vulnerability of the region in terms of the physical structure is moderate and downward. Additionally, the social vulnerability of the area is also above average. …”
Get full text