The curated Lactobacillus acidophilus NCFM genome provides insights into strain specificity and microevolution by Meichen Pan, Sarah O’Flaherty, Ashley Hibberd, Svetlana Gerdes, Wesley Morovic, Rodolphe Barrangou

“…Abstract Background The advent of next generation sequencing technologies has enabled a surge in the number of whole genome sequences in public databases, and our understanding of the composition and evolution of bacterial genomes. Besides model organisms and pathogens, some attention has been dedicated to industrial bacteria, notably members of the Lactobacillaceae family that are commonly studied and formulated as probiotic bacteria. …”
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Natural indigo toxicity for aquatic and terrestrial organisms by Natália Oliveira de Farias, Marta Siviero Guilherme Pires, Bruna de Jesus Moreira, Amanda dos Santos, Harold Stanley Freeman, Peppi Toukola, Anjaina Fernandes de Albuquerque, Riikka Räisänen, Gisela de Aragão Umbuzeiro

“…These organisms are model organisms and representative of the environmental compartments where dye’s destination is expected. …”
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High-throughput tracking enables systematic phenotyping and drug repurposing in C. elegans disease models by Thomas J O'Brien, Ida L Barlow, Luigi Feriani, André EX Brown

“…In the absence of a validated drug target, phenotypic screening in model organisms provides a route for identifying candidate treatments. …”
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<i>Artemisia herba</i>-<i>alba</i> Essential Oil: Chemical Composition, Phytotoxic Activity and Environmental Safety by Beáta Baranová, Daniela Gruľová, Flavio Polito, Vincent Sedlák, Mária Konečná, Marta Mydlárová Blaščáková, Ismail Amri, Vincenzo De Feo, Janka Poráčová

“…In this work, the chemical composition of an EO from <i>Artemisia herba</i>-<i>alba</i> and its herbicidal properties were studied on two weeds (<i>Lolium multiflorum</i> and <i>Trifolium pratense</i>) and two crops (<i>Brassica napus</i> and <i>Hordeum vulgare</i>) and its environmental safety was also assessed using three model organisms: <i>Chaoborus</i> sp., <i>Tubifex tubifex</i> and <i>Eisenia foetida</i>. …”
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Genome-wide quantification of polycistronic transcription in Leishmania major by Janne Grünebast, Stephan Lorenzen, Joachim Clos

“…Regulation of gene expression in Leishmania but also in the related Trypanosoma is radically different from all eukaryotic model organisms, dispensing with regulated, gene-specific transcription, and relying instead on highly regulated translation. …”
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Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research by Benjamin Punz, Maja Brajnik, Joh Dokler, Jaleesia D. Amos, Litty Johnson, Katie Reilly, Anastasios G. Papadiamantis, Amaia Green Etxabe, Lee Walker, Diego S. T. Martinez, Steffi Friedrichs, Klaus M. Weltring, Nazende Günday-Türeli, Claus Svendsen, Christine Ogilvie Hendren, Mark R. Wiesner, Martin Himly, Iseult Lynch, Thomas E. Exner

“…Application of the InstanceMaps tool (described herein) to research workflows of increasing complexity is presented to demonstrate its utility, starting from (i) documentation of a nanomaterial’s synthesis, functionalisation, and characterisation, over (ii) assessment of a nanomaterial’s transformations in complex media, (iii) description of the culturing of ecotoxicity model organisms Daphnia magna and their use in standardised tests for nanomaterials ecotoxicity assessment, and (iv) visualisation of complex workflows in human immunotoxicity assessment using cell lines and primary cellular models, to (v) the use of the instance map approach for the coordination of materials and data flows in complex multipartner collaborative projects and for the demonstration of case studies. …”
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Fieldwork on animals living in extreme conditions as a source of biomedical innovation by Yvon Le Maho, Aurélie Tasiemski, Fabrice Bertile, Philippe Bulet

“…Most biomedical research on animals is based on the handful of the so-called standard model organisms, i.e. laboratory mice, rats or Drosophila, but the keys to some important biomedical questions may simply not be found in these. …”
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Precision Psychobiotics for Gut–Brain Axis Health: Advancing the Discovery Pipelines to Deliver Mechanistic Pathways and Proven Health Efficacy by Rebecca F. Slykerman, Naomi Davies, Klara Vlckova, Kenneth J. O'Riordan, Shalome A. Bassett, James Dekker, Harriët Schellekens, Niall P. Hyland, Gerard Clarke, Elaine Patterson

“…Combining this information with knowledge from functional assays across in vitro and ex vivo domains and incorporating model organisms can prime the discovery pipelines with the most promising and rationally selected psychobiotic candidates.…”
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Efficacy of non-invasive ventilation and oxygen therapy on immunocompromised patients with acute hypoxaemic respiratory failure: protocol for a systematic review and meta-analysis... by Juhong Shi, Gang Liu, Meng Wang, Tao Wang, Yi Li, Yi Yang, Xuezhong Yu, Huadong Zhu, Yong Ma, Zongru Li, Lixi Zhang, Kun He, Jianqiang He

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Silk Protein Gene Engineering and Its Applications: Recent Advances in Biomedicine Driven by Molecular Biotechnology by Ji X, Li Y, Wang J, Wang G, Ma B, Shi J, Cui C, Wang R

“…This review outlines the roles of major model organisms, such as silkworms and spiders, in silk protein production, and provides a detailed introduction to the applications of gene editing technologies (eg, CRISPR-Cas9), transgenic expression technologies, and synthetic biology techniques in silk protein genetic engineering. …”
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Deviant Behaviors of Students in Educational System: A Meta-synthesis Model-Building Theory by Mehdi Mohammaadi, Farzane Deimehkar Haghighi

“…After analyzing the qualitative data and extracting components of the model organized into open codes, axial codes, and selective codes, a robust model was designed. …”
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