Molecular insight into reproductive toxicity and transgenerational effects of Cadmium exposure on Drosophila melanogaster by Yi Pan, Ke Fan, Linhao Zong, Yantao Luo, Xin Ni, Dong Chen, Jinjun Qian, Fei Ma, Jie Cheng, Miao Guan

“…Here, we employed fruit fly (Drosophila melanogaster) as a model organism to examine the reproductive performance across five generations by parental exposure to varying concentrations of Cd (5, 50, and 500 μM). …”
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Mechanisms underlying the effects of cyanogenesis on development and reproduction of Tetranychus urticae: Insights from enzyme activity and gene expression aspects by Mufeng Wu, Xiao Liang, Ying Liu, Chunling Wu, Xingkui An, Zihua Zhao, Guifeng Hao, Ijiti Oluwole Gregory, Zhihong Li, Qing Chen

“…To fill those knowledge gaps, the two-spotted spider mite (TSSM), Tetranychus urticae, was used as a model organism to elucidate the toxic mechanism of HCN. …”
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A concept of natural genome reconstruction. Part 2. Effect of extracellular double-stranded DNA fragments on hematopoietic stem cells by V. S. Ruzanova, S. G. Oshikhmina, A. S. Proskurina, G. S. Ritter, S. S. Kirikovich, E. V. Levites, Y. R. Efremov, T. V. Karamysheva, M. I. Meschaninova, A. L. Mamaev, O. S. Taranov, A. S. Bogachev, S. V. Sidorov, S. D. Nikonov, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, E. V. Dolgova, S. S. Bogachev

“…It was shown with mouse and human model organisms that CD34+ hematopoietic bone marrow progenitors take up fragments of extracellular double-stranded DNA through a natural mechanism. …”
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Deciphering the functional roles of PE18 and PPE26 proteins in modulating Mycobacterium tuberculosis pathogenesis and immune response by Aquib Ehtram, Mohd Shariq, Neha Quadir, Neha Quadir, Salma Jamal, Manjunath Pichipalli, Sheeba Zarin, Sheeba Zarin, Javaid Ahmad Sheikh, Nasreen Z. Ehtesham, Seyed E. Hasnain, Seyed E. Hasnain

“…Despite their importance, the roles and molecular interactions of PE18 and PPE26 in Mtb pathogenesis require further investigation.MethodsWe explored the roles of PE18 and PPE26 using recombinant Mycobacterium smegmatis (Msmeg) as a model organism. Protein-protein interactions were analyzed biochemically to identify partners within the ESX-5 secretion system, including EspG5 and other PE/PPE proteins. …”
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Fish gut microbiome and its application in aquaculture and biological conservation by Nusrat Hasan Kanika, Nusrat Hasan Kanika, Nusrat Hasan Kanika, Nusrat Liaqat, Nusrat Liaqat, Nusrat Liaqat, Huifan Chen, Huifan Chen, Huifan Chen, Jing Ke, Jing Ke, Jing Ke, Guoqing Lu, Jun Wang, Jun Wang, Jun Wang, Chenghui Wang, Chenghui Wang, Chenghui Wang

“…This review explores the composition and abundance of gut bacterial communities in key aquaculture fish groups—cyprinids, ictalurids (catfish), salmonids, and cichlids (tilapia)—alongside the model organism zebrafish, across diverse geographic regions. …”
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Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation by S.Z. Raduan, Q.U. Ahmed, M.R.A. Rusmili, A.S.M. Sabere, M.S. Haris, M.F. Shaikh, W.A.W. Sulaiman, M.H. Mahmood

“…To validate the zebrafish as a suitable model organism for AD, the study examined the effects of 2 neurotoxin agents, aluminium chloride (AlCl3) and okadaic acid (OKA). …”
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Expression‐based machine learning models for predicting plant tissue identity by Sourabh Palande, Jeremy Arsenault, Patricia Basurto‐Lozada, Andrew Bleich, Brianna N. I. Brown, Sophia F. Buysse, Noelle A. Connors, Sikta Das Adhikari, Kara C. Dobson, Francisco Xavier Guerra‐Castillo, Maria F. Guerrero‐Carrillo, Sophia Harlow, Héctor Herrera‐Orozco, Asia T. Hightower, Paulo Izquierdo, MacKenzie Jacobs, Nicholas A. Johnson, Wendy Leuenberger, Alessandro Lopez‐Hernandez, Alicia Luckie‐Duque, Camila Martínez‐Avila, Eddy J. Mendoza‐Galindo, David Cruz Plancarte, Jenny M. Schuster, Harry Shomer, Sidney C. Sitar, Anne K. Steensma, Joanne Elise Thomson, Damián Villaseñor‐Amador, Robin Waterman, Brandon M. Webster, Madison Whyte, Sofía Zorilla‐Azcué, Beronda L. Montgomery, Aman Y. Husbands, Arjun Krishnan, Sarah Percival, Elizabeth Munch, Robert VanBuren, Daniel H. Chitwood, Alejandra Rougon‐Cardoso

“…Abstract Premise The selection of Arabidopsis as a model organism played a pivotal role in advancing genomic science. …”
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Corrigendum to “p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation” [Neoplasia (2019) 21, 908–920] by Jingjing Wang, Ning Zhang, Minggang Peng, Xiaohui Hua, Chao Huang, Zhongxian Tian, Qipeng Xie, Junlan Zhu, Jingxia Li, Haishan Huang, Chuanshu Huang

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The efficacy of available supplements and medical drugs in longevity medicine - a review by Michał Łata, Małgorzata Chyćko, Kinga Przyborowska, Justyna Kwiecień, Mateusz Rukat, Agnieszka Strojny, Robert Siemiątkowski

“…This paper reviews data on model organisms concerning the effects of widely used drugs and dietary supplements on the lifespan of model organisms. …”
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Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice by Hua Yang, Mengjie Zhang, Jiahao Shi, Yunhe Zhou, Zhipeng Wan, Yicheng Wang, Yinghan Wan, Jun Li, Zhugang Wang, Jian Fei

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Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model by Hung-Chih Chen, Yu-Che Cheng, Marvin L. Hsieh, Po-Ju Lin, Emily F. Wissel, Theodore Steward, Cindy M. C. Chang, Jennifer Coonen, Timothy A. Hacker, Timothy J. Kamp, Patrick C. H. Hsieh

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Systematic screening and dynamic profiling of germline regulatory pathways and spermatogonial surface markers in a bivalve mollusc by Liangjie Liu, Ya Shu, Tian Liu, Huilan Wei, Yaxin Yang, Lijing Zhang, Xiaohui Ma, Guoqing Li, Yajuan Li, Shi Wang, Lingling Zhang

“…This approach will facilitate the culture and manipulation of spermatogonia in non-model organisms, which may contribute to genetic improvement in aquaculture.…”
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Identification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis by Aleksandra Antonczyk, Katarzyna Kluzek, Natalia Herbich, Mahdi Eskandarian Boroujeni, Bart Krist, Dorota Wronka, Anna Karlik, Lukasz Przybyl, Adam Plewinski, Joanna Wesoly, Hans A. R. Bluyssen

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THE ORIGIN OF SYNAPTONEMAL COMPLEX PROTEINS. SEARCH FOR RELATED PROTEINS IN PROTEOMES OF ALGAE, LOWER FUNGI, MOSSES, AND PROTOZOANS by T. M. Grishaeva, Yu. F. Bogdanov

“…In the proteomes of green and brown algae, mosses, a number of lowest fungi, Euglenozoa, Apicomplexa, and some other unicellular eukaryotes, proteins containing the HORMA domain show the greatest similarity to SC proteins of the model organisms. They are close to proteins of lateral SC elements of higher eukaryotes, also bearing the HORMA domain. …”
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Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis by Hiroya Yurimoto, Masahide Oku, Yasuyoshi Sakai

“…These features have made methylotrophic yeasts attractive hosts for the production of heterologous proteins and useful model organisms for the study of peroxisome biogenesis and degradation. …”
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Digit Tip Injuries: Current Treatment and Future Regenerative Paradigms by Travis J. Miller, Peter L. Deptula, Gregory M. Buncke, Zeshaan N. Maan

“…Despite the increased knowledge base on model organisms regarding regenerative paradigms, there is a lack of application of regenerative medicine techniques in clinical practice in regard to digit tip injury. …”
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Agriculture biologique, proximité et paysage by Nicolas Boivin

“…This paper is based on epistemical thoughts with the example of organic farming in the Paris-region (in comparison with the mainstream agricultural model). Organic farming is a marginal activity in this region, it has just begun to carve landscapes which are inserted between intensive farming landscapes.…”
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Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis by Adam K. Walker, Julie D. Atkin

“…In this paper, we present evidence from studies of genetics, model organisms, and patient tissues which indicate an active role for PDI and ER stress in ALS disease processes.…”
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A Heating and Cooling Stage With Fast Temporal Control for Biological Applications by Manon Valet, Juan M. Iglesias-Artola, Falk Elsner, Anatol W. Fritsch, Otger Campas

“…We envision that this device could benefit the communities using model and non-model organisms with physiological temperatures different from typical mammalian cell culture incubation in biomedical research.…”
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