Radiomics signature for dynamic monitoring of tumor inflamed microenvironment and immunotherapy response prediction by Enriqueta Felip, Paolo Nuciforo, Elena Garralda, Joan Frigola, Ramon Amat, Garazi Serna, Francesco Grussu, Kinga Bernatowicz, Olivia Prior, Marta Ligero, Christina Zatse, Rodrigo Toledo, Manel Escobar, Raquel Perez-Lopez

“…Despite demonstrating progression disease at the first follow-up, patients within the inflamed status group, identified by CT-TIME, exhibited significantly prolonged progression-free survival (PFS), with some surpassing 5 months, suggesting a potential phenomenon of pseudoprogression. Cox models using aggregated CT-TIME scores from baseline images revealed a statistically significant reduction in the risk of PFS in the pan-cancer cohort (HR 0.62, 95% CI 0.44 to 0.88, p=0.007), and Kaplan-Meier analysis further confirmed substantial differences in PFS between patients with inflamed and uninflamed status (log-rank test p=0.009).Conclusions The signature holds promise for impacting clinical decision-making, pan-cancer patient stratification, and treatment outcomes in immune checkpoint therapies.…”
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The protein composition of human adenovirus replication compartments by Paloma Hidalgo, Amada Torres, Pierre M. Jean Beltran, Gamaliel López-Leal, Luca D. Bertzbach, Thomas Dobner, S. J. Flint, Ileana M. Cristea, Ramón A. González

“…Our data further suggest potential candidate targets for therapeutic intervention and provide mechanistic insights into the molecular basis of virus-host interactions.IMPORTANCEHuman adenoviruses serve as models for studying respiratory viruses and have provided critical insights into viral genome replication and gene expression, as well as the control of virus-host interactions. …”
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Analisis Pengembangan Jaringan Komputer UIN Sunan Kalijaga Yogyakarta Menggunakan Perbandingan Protokol Routing Statik dan Routing Dinamis OSPF by Rahmadhan Gatra, Bambang Sugiantoro

“…The study was made based on modeling (simulation) based on EVE-NG applications. …”
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Life cycle greenhouse gas emissions of conventional and alternative steel production methods in countries dependent on energy import: A South Korean case study by Juha Lee, Gyuna Kwak, Yujin Jung, Wonjae Choi

“…The data used in the analysis was selected through a literature review and thermodynamic modeling of the process. The life cycle assessment revealed that, coal blast furnaces emit 1612 kg-CO2-eq.…”
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Zorlu Yaşam Olaylarını Anlamlandırmada Dünyaya İlişkin Varsayımlar ve Din by Muharrem Aka

“…‘Parçalanmış Varsayımlar Modeli’ insanların temel inançlarını açıklamaya yönelik kuramsal bir çerçeve sunmaya çalışmıştır. Bu modele göre insanlar ‘dünyanın iyiliği’, ‘dünyanın anlamlılığı’ ve ‘kendilik değeri’ olarak temelde üç ana varsayıma sahiptirler. …”
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Agricultural Drought Assessment using Remote Sensing Data (Case study: Tuyserkan County) by Maedeh Malmir, Kamran Shayesteh, Iman Pazhouhan

“…Remote sensing allows for the study of drought's effects on plant growth, leading to more accurate and impactful results in drought modeling. Materials and Methods Tuyserkan city covers an area of 1,556 square kilometers, 7.98% of the area of Hamedan province, in the west of Iran, and it is located along the Zagros mountain range. …”
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Arginase-1-specific T cells target and modulate tumor-associated macrophages by Mads Hald Andersen, Inés Lecoq, Ayako Wakatsuki Pedersen, Evelina Martinenaite, Shamaila Munir Ahmad, Maria Perez-Penco, Lucia Lara de la Torre, Marion Chapellier, Lars Rønn Olsen, Mia Aaboe-Jørgensen, Hannah Jorinde Glöckner, Anne Mette Askehøj Rømer

“…We previously reported the existence of Arg1-specific memory T cells among peripheral blood mononuclear cells (PBMCs) and described that Arg-1-based immune modulatory vaccines (IMVs) control tumor growth and alter the M1/M2 macrophage ratio in murine models of cancer. In the present study, we investigated how Arg1-specific T cells can directly target TAMs and influence their polarization.Methods Murine Arg1-specific CD4+T cells isolated from splenocytes of animals vaccinated with an Arg1-derived peptide in the adjuvant montanide were co-cultured with either in vitro M2-differentiated bone marrow-derived macrophages or ex vivo isolated F4/80+TAMs. …”
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An Arctic sea ice concentration data record on a 6.25 km polar stereographic grid from 3 years of Landsat-8 imagery by H.-S. Jung, S.-M. Lee, S.-M. Lee, J.-H. Kim, K. Lee

“…The vast amount of Landsat-8 SIC generated in this study may also be used to train deep-learning models for the estimation of Arctic SIC coverage. …”
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Investigating the Efficacy of the Web-Based Common Elements Toolbox (COMET) Single-Session Interventions in Improving UK University Student Well-Being: Randomized Controlled Trial by Jeffrey Lambert, Maria Loades, Noah Marshall, Nina Higson-Sweeney, Stella Chan, Arif Mahmud, Victoria Pile, Ananya Maity, Helena Adam, Beatrice Sung, Melanie Luximon, Keren MacLennan, Clio Berry, Paul Chadwick

“…The data were analyzed using linear mixed models and reported in accordance with the CONSORT-EHEALTH (Consolidated Standards of Reporting Trials of Electronic and Mobile Health Applications and Online Telehealth) checklist. …”
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Green Tea Extract (<i>Theaceae</i>; <i>Camellia sinensis</i> L.): A Promising Antimicrobial, Anti-Quorum Sensing and Antibiofilm Candidate Against Multidrug-Resistant <i>Campylobac... by Mona S. Emara, Ahmed M. Ammar, Ashraf M.O. Abdelwahab, Attia A. Elgdawy, Adel Abdelkhalek, Elena Pet, Gabi Dumitrescu, Mirela Ahmadi, Norhan K. Abd El-Aziz

“…Further in vivo studies in animals’ models should be performed to provide evidence of concept for the implementation of this alternative candidate for the mitigation of MDR <i>Campylobacter</i> infections in the future.…”
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Association of systemic immune-inflammatory index with in-stent restenosis in patients with and without diabetes mellitus by Xunwei Deng, Xunwei Deng, Xunwei Deng, Qiaoting Deng, Qiaoting Deng, Qiaoting Deng, Qunji Zhang, Qunji Zhang, Qunji Zhang, Jingyuan Hou, Jingyuan Hou, Jingyuan Hou

“…Multivariable logistic regression models were employed to assess the associations between SII and ISR prevalence. …”
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Partner conflict during their index pregnancy and its correlates among a cohort of six weeks postpartum women in Ethiopia by Solomon Abrha Damtew, Niguse Tadele Atnafu, Mahari Yihdego Gidey, Tesfamichael Awoke Sisay, Metages Yohannes

“…Multilevel binary logistics regression statistical modeling was employed to identify correlates of IPV. …”
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Plateau hypoxia improves tumor immune microenvironment and inhibits subcutaneous tumor growth of colorectal cancer by ZHAO Sijie, WANG Meng, GAO Yuan

“…Colorectal tumor MC38 cells and colon adenocarcinoma CT26 cells were subcutaneously implanted into C57BL/6 mice and BALB/C mice， respectively to construct subcutaneous tumor-bearing mouse models. Then the tumor size and weight were measured in 4 groups of mice. …”
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Relato de uma extensão em tempos de isolamento social: Criação de um recurso educacional sobre matemática na pandemia de COVID-19 by Leila Thomazelli Thieghi, Fabio Luiz Sant'Anna Cuppo

“…This experience report details how a powerful educational resource was created, focusing on the application of mathematical modeling to the data released about the COVID-19 pandemic for educational purposes. …”
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Sequential use of low-load-blood-flow-restricted vs. high-load resistance training on neuromuscular activation, hypertrophy and neuromuscular performance by Romina Ledergerber, Paul Ritsche, Eric Lichtenstein, Martin Keller

“…Measurements at baseline including familiarization (PRE1 and PRE2), 8 weeks (MID) and 10 weeks (POST) included maximal voluntary contraction of knee extensors (MVC), leg press strength (LP), voluntary activation (VA, via electrical muscle stimulation) and vastus lateralis muscle volume (V_VL, via ultrasound at 30-70% femur length). Linear mixed models were used to analyze group differences over time, with Cohen’s d effect sizes. …”
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Research hotspots and trends in the field of quality of life of oral cancer patients: A visual analysis based on CiteSpace (基于CiteSpace口腔癌患者生活质量研究热点的可视化分析)... by YANG Ting (杨婷), CHEN Siyi (陈思忆), ZHENG Xiaodan (郑晓丹), YANG Yi (杨怡)

“…Conclusion It is recommended that researchers learn from the advanced theories and models of foreign countries to further develop a quality of life assessment scale more suitable for oral cancer patients in China. …”
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Incidence, Risk Factors, and Outcomes of Perioperative Atrial Fibrillation following Noncardiothoracic Surgery: A Systematic Review and Meta-Regression Analysis of Observational St... by Yamini Subramani, Omar El Tohamy, Daniil Jalali, Mahesh Nagappa, Homer Yang, Ashraf Fayad

“…We reported data on demographics, comorbidities, and perioperative complications as mean difference (MD) or odds ratios (OR) and corresponding 95% confidence interval (CI) using random effects models. A two-sided P value of less than 0.05 was considered significant. …”
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Acute phase responses in clinically healthy multiparous Holsteins with and without calcium dysregulation during the early postpartum period by J.A. Seminara, C.R. Seely, J.A.A. McArt

“…Patterns of protein concentrations in blood over time were compared using linear mixed effects models including fixed effects of calcium status group, time, parity group, farm, relevant 2-way interactions, and the random effect of cow. …”
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Bibliometric analysis of laryngeal cancer treatment literature (2003–2023) by Yan Zhao, Jiancheng Xue

“…Current research hotspots include disease prognosis, models, clinical trials, tumor recurrence, and surveillance. …”
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A Phenologically Simplified Two-Stage Clumping Index Product Derived from the 8-Day Global MODIS-CI Product Suite by Ge Gao, Ziti Jiao, Zhilong Li, Chenxia Wang, Jing Guo, Xiaoning Zhang, Anxin Ding, Zheyou Tan, Sizhe Chen, Fangwen Yang, Xin Dong

“…This study provides relatively reliable CI datasets that capture the general trend of seasonal CI variations and simplify potential applications in modeling ecological, meteorological, and other surface processes at both global and regional scales. …”
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