Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial by Alicia Monreal-Bartolomé, Adoración Castro, M Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, María Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo, Jesus Montero-Marin

“…Differences between the groups were estimated using mixed effects linear regression models, and mediation evaluations were conducted using path analyses to evaluate the potential mechanistic role of positive and negative affectivity and openness to the future. …”
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Explorando el potencial de la inteligencia artificial en traumatología: respuestas conversacionales a preguntas específicas by F. Canillas del Rey, M. Canillas Arias

“…Material and methods: Three «chatbot» models (ChatGPT, Bard and Perplexity) were analyzed by answering 114 questions from the MIR. …”
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TILTomorrow today: dynamic factors predicting changes in intracranial pressure treatment intensity after traumatic brain injury by Shubhayu Bhattacharyay, Florian D. van Leeuwen, Erta Beqiri, Cecilia A. I. Åkerlund, Lindsay Wilson, Ewout W. Steyerberg, David W. Nelson, Andrew I. R. Maas, David K. Menon, Ari Ercole, the CENTER-TBI investigators and participants

“…We developed the TILTomorrow modelling strategy, which leverages recurrent neural networks to map a token-embedded time series representation of all variables (including missing values) to an ordinal, dynamic prediction of the following day’s five-category therapy intensity level (TIL(Basic)) score. …”
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Association between physical activity, smartphone usage, and obesity risk among Korean adolescents: A cross-sectional study based on 2021 Korean adolescent health behavior survey by Haoyuan Li, Jaeyoung Choi, Aram Kim, Guifang Liu

“…To examine the impact of key exposure factors-including PA, muscle strengthening exercises (MSE), sedentary behavior, and smartphone usage-on obesity risk, binary logistic regression models were used, adjusting for grade level, economic status, and other potential confounders. …”
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Cerebrospinal fluid β2-microglobulin promotes the tau pathology through microglia–astrocyte communication in Alzheimer's disease by Zehu Sheng, Lanyang Wang, Ming Chen, Fuxin Zhong, Shijing Wu, Shuyu Liang, Jiaqi Song, Lihua Chen, Yingxi Chen, Shiyu Chen, Weihua Yu, Yang Lü

“…Multiple linear regression, linear mixed effects models, and causal mediation analyses bootstrapped 10,000 iterations were used to investigate the underlying associations among β2M and CSF biomarkers at baseline and during a longitudinal visit. …”
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Integrating Videoconferencing Therapist Guidance Into Stepped Care Internet-Delivered Cognitive Behavioral Therapy for Child and Adolescent Anxiety: Noninferiority Randomized Contr... by Sonja March, Susan H Spence, Larry Myers, Martelle Ford, Genevieve Smith, Caroline L Donovan

“… BackgroundSelf-guided internet-delivered cognitive behavioral therapy (ICBT) achieves greater reach than ICBT delivered with therapist guidance, but demonstrates poorer engagement and fewer clinical benefits. Alternative models of care are required that promote engagement and are effective, accessible, and scalable. …”
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Targeting deubiquitinase USP7-mediated stabilization of XPO1 contributes to the anti-myeloma effects of selinexor by Junying Wang, Mengping Chen, Jinxing Jiang, Yike Wan, Xin Li, Minyue Zhang, Fei Xiao, Lu Zhong, Hua Zhong, Zhaoyu Qin, Jian Hou

“…The role of USP7 in modulating SEL sensitivity was analyzed in MM cell lines, primary CD138+ cells, and xenograft mouse models. Results SEL promotes the degradation of XPO1 in MM cells through the ubiquitin–proteasome pathway. …”
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Covid-19 pandemic-related changes in teleworking, emotional exhaustion, and occupational burnout: a cross-sectional analysis of a cohort study by Anshu Uppal, Nick Pullen, Hélène Baysson, Stephanie Schrempft, Aminata Rosalie Bouhet, María-Eugenia Zaballa, Julien Lamour, Mayssam Nehme, Idris Guessous, Silvia Stringhini, Elsa Lorthe, Specchio-COVID19 study group

“…Participants were categorized based on self-reported telework frequency changes: “no change,” “increase,” “decrease,” “never telework,” and “not possible to telework.” Adjusted regression models for each of the study samples were used to estimate associations between telework changes and burnout outcomes, accounting for sociodemographic, household, and work-related factors. …”
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Vision impairment and associated daily activity limitation: A systematic review and meta-analysis. by Masoud Rahmati, Lee Smith, Laurent Boyer, Guillaume Fond, Dong Keon Yon, Hayeon Lee, Tarnjit Sehmbi, Mapa Prabhath Piyasena, Shahina Pardhan

“…Meta-analyses were performed using random effects models to calculate the pooled effect size, expressed as odds ratio (OR) with corresponding 95% confidence interval (CI) of each outcome.…”
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Vulnerabilidad sísmica y capacidad de carga de un puente atirantado basados en confiabilidad estructural Seismic vulnerability and loading capacity of a wire strained bridge based... by Edgar Muñoz, Federico Nunez, Jorge A Rodríguez, Alfonso Ramos, Camilo Otálora

“…Additionally, the study explains structural models on finite elements, which were developed for the bridge, as well as its calibration process based on the loading test, and dynamical properties determined on experimental basis. …”
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Indication of frailty transitions on 2-year adverse health outcomes among older Chinese inpatients: Insight from a multicenter prospective cohort study. by Miao Yu, Jiaqi Ding, Xinjuan Wu, Xianxiu Wen, Jingfen Jin, Hui Wang, Dongmei Lv, Shengxiu Zhao, Jing Jiao, Tao Xu

“…Cox proportional hazard regression, generalized linear models and linear regression was used to examine the association between frailty transitions and adverse health outcomes.…”
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Adaptive Just-in-Time Intervention to Reduce Everyday Stress Responses: Protocol for a Randomized Controlled Trial by Jillian A Johnson, Matthew J Zawadzki, Martin J Sliwinski, David M Almeida, Orfeu M Buxton, David E Conroy, David Marcusson-Clavertz, Jinhyuk Kim, Robert S Stawski, Stacey B Scott, Christopher N Sciamanna, Paige A Green, Emily M Repka, Meynard John L Toledo, Nicole L Sturges, Joshua M Smyth

“…We will use mixed-effects models to evaluate differences in person-specific stress responses between the intervention and control groups. …”
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Assessing the Future ODYSEA Satellite Mission for the Estimation of Ocean Surface Currents, Wind Stress, Energy Fluxes, and the Mechanical Coupling Between the Ocean and the Atmosp... by Marco Larrañaga, Lionel Renault, Alexander Wineteer, Marcela Contreras, Brian K. Arbic, Mark A. Bourassa, Ernesto Rodriguez

“…Despite significant improvements in the representation of western boundary currents and mesoscale eddies in numerical models, some discrepancies remain when comparing numerical simulations with satellite observations. …”
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The Joint Association of Sleep Quality and Outdoor Activity with Asthma and Allergic Rhinitis in Children: A Cross-Sectional Study in Shanghai by Lu R, Zhang Y, Chen Y, Lyu J, Li R, Kang W, Zhao A, Ning Z, Hu Y, Lin X, Tong S, Lu Z, Li S

“…Multivariable logistic regression models were used to analyze the correlation of sleep quality, outdoor activities and their combination with children’s asthma and allergic rhinitis.Results: The overall prevalence of asthma and allergic rhinitis in our sampled children were 10.2% and 17.6%, respectively. …”
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Depression symptom severity and behavioral impairment in school-going adolescents in Uganda by Ronald Anguzu, Catherine Abbo, Julia Dickson-Gomez, Max Bobholz, Arthur Kiconco, Abdul R. Shour, Richard Kabanda, Kenneth Kalani, Laura D. Cassidy

“…Modified Poisson regression models tested the independent association between depressive symptom severity and behavioral impairment. …”
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Dietary patterns related to triglyceride glucose index and risk of type 2 diabetes: a large-scale cohort study by Dong Liu, Dong Liu, Ziwei Liu, Yue Wu, Yan Hong, Jinghao Fang, Ying Lu, Guangfei Xu, Peipei Kang, Tong Liu, Li-Hua Chen, Li-Hua Chen

“…The associations between the TyG index, related dietary pattern scores, and T2DM risk were evaluated using Cox regression models.ResultsDuring a median follow-up period of 11.2 years, 3,585 participants developed T2DM. …”
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Intratumoral BO-112 in combination with radiotherapy synergizes to achieve CD8 T-cell-mediated local tumor control by Helena Escuin-Ordinas, Ignacio Melero, Marisol Quintero, Jose Luis Perez-Gracia, Maite Alvarez, Maria E Rodriguez-Ruiz, Miguel F Sanmamed, Paloma Sanchez-Mateos, Inmaculada Rodríguez López, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Eneko Garate-Soraluze, Victor Diaz Pascual, Leire Arbea Moreno

“…BO-112 and focal irradiation were used to make the proof-of-concept for local immunotherapy plus radiation therapy combinations.Methods Murine transplantable tumor cell lines (TS/A, MC38 and B16-OVA) were used to show increased immunogenic features under irradiation, as well as in bilateral tumor models in which only one of the lesions was irradiated or/and injected with BO-112. …”
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Evaluation of the Efficacy of Stem Cell Therapy in Ovariectomized Osteoporotic Rats Based on Micro-CT and Dual-Energy X-Ray Absorptiometry: A Systematic Review and Meta-Analysis by Zhencheng Xiong, Ping Yi, Jialiang Lin, Shengfeng Qiu, Li Shu, Chi Zhang

“…Due to the tissue regenerative potential of stem cell transplantation, it is now used in the treatment of various disease models such as osteoporosis. The purpose of this work is to carry out a systematic review and meta-analysis of the efficacy of stem cell therapy in ovariectomized (OVX) osteoporotic rats. …”
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Assessment of six insulin resistance surrogate indexes for predicting stroke incidence in Chinese middle-aged and elderly populations with abnormal glucose metabolism: a nationwide... by Luqing Jiang, Tengxiao Zhu, Wenjing Song, Ying Zhai, Yu Tang, Fengxia Ruan, Zichen Xu, Lei Li, Xia Fu, Daoqin Liu, Aidong Chen, Qiwen Wu

“…Multivariate logistic regression models were applied to analyse the relationships of IR surrogate indexes with stroke risk. …”
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Ventilatory variables and computed tomography features in COVID-19 ARDS and non–COVID-19-related ARDS: a prospective observational cohort study by Li-Chung Chiu, Hsin-Hsien Li, Yu-Hsiang Juan, How-Wen Ko, Scott Chih-Hsi Kuo, Chung-Shu Lee, Tien-Ming Chan, Yu-Jr Lin, Li-Pang Chuang, Han-Chung Hu, Kuo-Chin Kao, Ping-Chih Hsu

“…Multivariable logistic regression models revealed that Sequential Organ Failure Assessment (SOFA) score was independently associated with mortality in the COVID-19 group. …”
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