Exploring under-five child malnutrition in Bangladesh: Analysis using the Extended Composite Index of Anthropometric Failure (ECIEF) by Farzana Akhter Bornee, Mohammad Rocky Khan Chowdhury, Badrun Naher Siddique, Baki Billah, Farjana Akter, Md Nazmul Karim

“…Multilevel logistic regression models identified factors associated with malnutrition. …”
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Physical behaviours during pregnancy may alter the association of maternal insulin sensitivity with neonatal adiposity: a prospective pre-birth cohort of mother-child pairs by Piraveena Satkunanathan, Catherine Allard, Myriam Doyon, Patrice Perron, Luigi Bouchard, Marie-France Hivert, Tricia M. Peters

“…Results Lower Matsuda index was associated with higher birthweight z-score (ß±SE= -0.180 ± 0.056, p = 0.001) and with higher sum of skinfold thickness (neonatal adiposity) (ß±SE=-0.877 ± 0.383, p = 0.02) in fully adjusted models. The association between Matsuda index and sum of skinfold thickness was weaker in women with higher levels of physical activity at V2 ([high ≥ 1.26 kcal/kg/day] ß±SE=-0.15 ± 0.65) compared to women with lower levels [low < 1.26 kcal/kg/day] ß±SE=-1.36 ± 0.51, P-interaction = 0.01). …”
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Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study by Chunhui Zhou, Ganfeng Yang, Marc Theeboom, Hua Yang, Ruiting Zhu, Zijian Zhou, Dong Zhu

“…Multivariable linear regression models were employed to further explore these relationships and to assess the moderating role of ADLs.ResultsSignificant positive correlations were found between visual function and cognitive performance, particularly with Visual Function Index (VFI) showing a strong initial correlation with the total MoCA score (r = 0.61, p &lt; 0.001), which was attenuated after adjusting for ADL (β = 0.06, p = 0.23). …”
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Quality of life in early breast cancer patients after adjuvant accelerated partial-breast irradiation (APBI) in randomized trial by Petr Burkon, Iveta Selingerova, Miroslav Vrzal, Milos Holanek, Oldrich Coufal, Katerina Polachova, Vera Andraskova, Sachin R. Jhawar, Pavel Slampa, Tomas Kazda, Marek Slavik

“…Patients were requested to complete the official Czech translation of the EORTC QoL questionnaires, including QLQ-C30 and QLQ-BR45, before radiation (baseline), at the end of radiation (M0) and 1 (M1), 3 (M3), 6 (M6), 12 (M12), and 24 (M24) months after radiation. Linear regression models were used to analyze differences in HRQoL between the arms. …”
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Negative effects of adverse childhood experiences and absence of positive childhood experiences on healthcare employees: survey findings built on 10 years of trauma-informed develo... by Laneita Williamson, Laneita Williamson, Stephanie S. Daniel, Jennifer Carter, Adam Ridenhour, Camila A. Pulgar, Yasmin Gay, Beata Debinski

“…Multivariable, hierarchical models regressed categorized total ACEs (ref 0, 1–3, 4–10) and total PCEs (ref 6–7, 3–5, 0–2) together on dichotomized dependent variables. …”
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Behavioral risk factors and socioeconomic inequalities in ischemic heart disease mortality in the United States: A causal mediation analysis using record linkage data. by Yachen Zhu, Laura Llamosas-Falcón, William C Kerr, Jürgen Rehm, Charlotte Probst

“…Counterfactual-based causal mediation analyses with Cox proportional hazards models were performed to quantify the contributions of 4 BRFs (smoking, alcohol use, physical inactivity, and BMI) to socioeconomic inequalities in IHD mortality. …”
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Association between lifestyle risk factors and mortality in the Mexico City prospective study by Paloma Ferrero-Hernández, Gary O’Donovan, Fanny Petermann-Rocha, Diego G. D. Christofaro, Carlos Cristi-Montero, Adilson Marques, Marcelo de Maio Nascimento, Claudio Farías-Valenzuela, Leandro F. M. Rezende, Gerson Ferrari

“…Multivariable Cox regression models were used to estimate the associations of lifestyle risk factor score (ranging from 0 to 5) with all-cause and cause-specific mortality (cardiovascular disease, renal or hepatobiliary diseases, diabetes, respiratory diseases, cancer and all-cause mortality). …”
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Comparison of the efficacy of LTCBDE and LCBDE for common bile duct stones: a systematic review and meta-analysis by Bin Zheng, Yixin Lu, Erqi Li, Ziyu Bai, Kaiqian Zhang, Jian Li, Jian Li

“…RevMan 5.4 was used for meta-analysis of fixed-effects and random-effects models.ResultsA total of 21 studies met the inclusion criteria, including 3065 patients in the LTCBDE group and 2,453 patients in the LCBDE group. …”
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Multiparametric MRI and artificial intelligence in predicting and monitoring treatment response in bladder cancer by Yuki Arita, Thomas C. Kwee, Oguz Akin, Keisuke Shigeta, Ramesh Paudyal, Christian Roest, Ryo Ueda, Alfonso Lema-Dopico, Sunny Nalavenkata, Lisa Ruby, Noam Nissan, Hiromi Edo, Soichiro Yoshida, Amita Shukla-Dave, Lawrence H. Schwartz

“…AI improves mpMRI segmentation and enhances radiomics feature extraction effectively. Predictive models integrate imaging biomarkers and clinical data using AI tools. …”
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Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China by Chaojuan Huang, Hongtao You, Yuyang Zhang, Ligang Fan, Xingliang Feng, Naiyuan Shao

“…Stroke cases were identified based on self-reported, physician-confirmed diagnoses. Logistic regression models were established to determine the correlation between HbA1c/HDL-C and stroke prevalence (2011) as well as between cumulative mean HbA1c/HDL-C (2011–2015) and new stroke incidence (2015–2018). …”
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Impact of a positive end-expiratory pressure on oxygenation, respiratory compliance, and hemodynamics in obese patients undergoing laparoscopic surgery in reverse Trendelenburg pos... by Gulfairus A. Yessenbayeva, Aizhan M. Meyerbekova, Sergey I. Kim, Murat B. Zhumabayev, Gulbanu S. Berdiyarova, Sanzhar B. Shalekenov, Dinara S. Zharlyganova, Irina Y. Mukatova, Yekaterina A. Yukhnevich, Dmitriy A. Klyuyev, Andrey I. Yaroshetskiy

“…We calculated mean differences (MD) with 95% confidence intervals (CI), and predictive intervals (PI) using random-effects models. The Cochrane Bias Risk Assessment Tool was applied. …”
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Elevated Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict Incident Ischemic Cardiovascular Events in a Longitudinal and Prospective AMI Aging Study by Zhao X, Zhao H, Chen R, Zhou J, Li N, Li J, Yan S, Liu C, Zhou P, Chen Y, Song L, Yan H

“…Initially, participants were stratified into three groups according to the tertile levels of FABP4, followed by further categorization based on various lipid profiles and specific inflammatory markers.Results: On follow-up (median 751 days, maximum 1506 days), a total of 158 ischemic events were recorded. 1) In multivariable models meticulously adjusted for age, gender, traditional coronary heart disease factors, Killip classification, and discharge medications, the association of elevated levels of FABP4 (Tertile 3 HR 1.618 [1.061 to 2.468], p=0.026), augmented concentrations of PTX3 (Tertile 3 HR 1.811 [1.211 to 2.710], p=0.004), or LL-37 (Tertile 3 HR 0.651 [0.433 to 0.981], p=0.040) with ischemic risk was markedly intensified. 2) Multivariate HRs associated with 1 standard deviation (SD) (mg/dL) increase in the FABP4 parameters were as follows in different subgroups. 1-SD difference in FABP4 was associated with a 23%, 23%, 21 and 29% increase in ischemic events over after fully adjusted the confounding risk factors among male, patients with hyperlipidemia, hypertension and diabetes respectively. 3) The Kaplan-Meier curve demonstrated significant differences between the tertiles of FABP4 index levels among all enrolled participants (p=0.0180).Conclusion: This study reinforces the utility of FABP4 for enhancing risk stratification specifically among older patients diagnosed with ST-elevation myocardial infarction.Keywords: FABP4, lipid profile, PTX3, LL-37, ischemic vascular events…”
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Building a Digital Health Research Platform to Enable Recruitment, Enrollment, Data Collection, and Follow-Up for a Highly Diverse Longitudinal US Cohort of 1 Million People in the... by Dave Klein, Aisha Montgomery, Mark Begale, Scott Sutherland, Sherilyn Sawyer, Jacob L McCauley, Letheshia Husbands, Deepti Joshi, Alan Ashbeck, Marcy Palmer, Praduman Jain

“… BackgroundLongitudinal cohort studies have traditionally relied on clinic-based recruitment models, which limit cohort diversity and the generalizability of research outcomes. …”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma &le;3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Shuanggang Chen,1,2,&ast; Han Qi,1,2,&ast; Hongtong Tan,1,2,&ast; Fei Cao,1,2 Lin Xie,1,2 Tao Huang,1,2 Ying Wu,3 Chunyong Wen,1,2 Yujia Wang,1,2 Lujun Shen,1,2 Weijun Fan1,2 1Department of Minimally Invasive Interventional Therapy, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 2State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 3Department of Interventional Therapy, Shenzhen second People’s Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Weijun Fan, Email fanwj@sysucc.org.cn; Lujun Shen, Email shenlj@sysucc.org.cnBackground: Salvage liver transplantation is promising for hepatocellular carcinoma(HCC) recurrence post-ablation but is significantly affected by recurrence beyond Milan Criteria (RBM).Materials and Methods: A retrospective cohort study of potentially transplantable HCC patients undergoing ablation between 2007 and 2017 assessed median time to recurrence beyond Milan Criteria(TRBM) via Kaplan-Meier curves and predictive capacity of recurrence and RBM for overall survival(OS) via Receiver Operating Characteristic Curves, and identified independent risk factors for TRBM and RBM via Cox and binary logistic regression models.Results: We enrolled 191 potentially transplantable patients with early-stage HBV-related HCC ≤ 3 cm who underwent ablation. …”
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Association between triglyceride-glucose (TyG) related indices and cardiovascular diseases and mortality among individuals with metabolic dysfunction-associated steatotic liver dis... by Yanan Qiao, Yue Wang, Cheng Chen, Yueqing Huang, Chunhua Zhao

“…Cox proportional hazards models and restricted cubic spline (RCS) were performed to evaluate the associations between TyG-related indices and the risk of overall CVD, coronary heart disease (CHD), stroke, all-cause mortality, and cardiovascular mortality. …”
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Impact of estimated glomerular filtration rate (eGFR) on in-hospital mortality: an age- and HIV status-specific retrospective cohort study in Uganda by Odong Christopher, Wang Yanmei, Makabayi Emmanuel Yeko, Doreen Mary Nanyunja, Kuule Julius Kabbali

“…Per-standard deviation(SD) increase in eGFR(48.60 mL/min/1.73m2) was associated with Hazard Ratio(HR) of 0.46[95%CI: 0.282–0.759, p = 0.002, β = -0.77] for IHM in fully adjusted models. When stratified by eGFR quartiles, using highest quartile(≥ 120 mL/min/1.73m2) as reference, HR was 1.08[95%CI: 0.276–4.226, p = 0.912, β =  + 0.08] for 99.0–120 mL/min/1.73m2; 4.08[95%CI: 1.284–12.954, p = 0.017, β =  + 1.41] for 66.8–99.0 mL/min/1.73m2, and 4.08[95%CI: 1.284–12.954, p = 0.037, β =  + 1.25] for < 66.8 mL/min/1.73m2. …”
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Abuse of patent rights for pharmaceuticals in wartime conditions by A.O. Kodynets, O.F. Doroshenko, I.P. Volynets, G.K. Dorozhko, V.O. Petrenko, V.V. Belitsky

“…The study employs general scientific and specialized methods of scientific cognition, including dialectical, formal-logical, system-structural, comparative-legal methods, as well as modeling, analysis, and synthesis. Together, these methods facilitated the organization, planning, and execution of the research. …”
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An ecological, environmental, and economic indicators-based approach towards enhancing sustainability in water and nutrient use for passion fruit cultivation in Colombia by Sonia Mercedes Polo-Murcia, Nesrine Chaali, Camilo Ignacio Jaramillo-Barrios, Sofiane Ouazaa, Victor Javier Polo, John Edisson Calderon Carvajal

“…Principal component analysis (PCA) was used to determine optimal irrigation and fertilization practices. Mixed linear models were applied to compare ecological and economic indicators. …”
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Impact of cariprazine on body weight and blood pressure among adults with bipolar I disorder, schizophrenia, or major depressive disorder in a real-world setting by Christoph U. Correll, Andrew J. Cutler, François Laliberté, Guillaume Germain, Sean D. MacKnight, Julien Boudreau, Sally W. Wade, Nadia Nabulsi, Huy-Binh Nguyen, Mousam Parikh

“…Changes were estimated using linear mixed-effects models fitted over measurements pre-index and on treatment; 95% CIs were derived from nonparametric bootstrap procedures. …”
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Pre-pregnancy BMI modifies the associations between triglyceride–glucose index in early pregnancy and adverse perinatal outcomes: a 5-year cohort study of 67,936 women in China by Li Li, Yulai Zhou, Huan Li, Juan Li, Lishi Huang, Weibin Wu

“…Multivariable logistic regression models were applied to explore the relationship between TyG index and APOs. …”
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