The Association Between Neutrophil‐Percentage‐to‐Albumin Ratio (NPAR) and Mortality Among Individuals With Cancer: Insights From National Health and Nutrition Examination Survey... by Xinyang Li, Meng Wu, Minxin Chen, Rufei Liu, Qingxu Tao, Yun Hu, Jinming Yu, Dawei Chen

“…We analyzed the relationship between NPAR and the risks of cancer incidence, all‐cause mortality, and cancer‐related mortality using weighted Logistic and Cox regression models, as well as trend tests. Restricted cubic spline analysis was employed to investigate NPAR's nonlinear relationship with mortality risk. …”
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A Vitamin Pattern Diet Is Associated with Decreased Risk of Gestational Diabetes Mellitus in Chinese Women: Results from a Case Control Study in Taiyuan, China by Qiong Chen, Yongliang Feng, Hailan Yang, Weiwei Wu, Ping Zhang, Keke Wang, Ying Wang, Jamie Ko, Jiaxin Shen, Lingling Guo, Feng Zhao, Wenqiong Du, Shouhang Ru, Suping Wang, Yawei Zhang

“…Dietary nutrient patterns were identified using factor analysis, and their associations with GDM risk were evaluated using unconditional logistic regression models adjusting for total energy intake, maternal age, high blood pressure, education, maternal body mass index (BMI), parity, and family history of diabetes. …”
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The efficacy of conservative management of micro-traumatic posterior shoulder instability by Lyn Watson, Prof DocBAppSci(Physio) GradDip, Simon Balster, BPhty(Hon), BSc (Hon), Sarah Warby, PhDB Physio (Hon), Ross Lenssen, BHSc(Physiotherapy), Gregory Hoy, MBBS, FRACS, FAOrthA, FACSP, Shane Barwood, MBBS, FRACS, Jacqui French, BPhysio, Bonnie Kerr, BHth ScMSports Physio, Sam Lawrence, DPT, BAppSc, PGCert, Charlotte Ganderton, PhDB Physio (Hon), Katherine Davis, BHuman Movt (ExSci), MPhysio, Tania Pizzari, PhDB Physio (Hon)

“…Treatment effects were determined using linear mixed models, with 95% confidence intervals. Significance was set at 0.05. …”
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Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective... by Itske Fraterman, Lucia Sacchi, Henk Mallo, Valentina Tibollo, Savannah Lucia Catherina Glaser, Stephanie Medlock, Ronald Cornet, Matteo Gabetta, Vitali Hisko, Vadzim Khadakou, Ella Barkan, Laura Del Campo, David Glasspool, Alexandra Kogan, Giordano Lanzola, Roy Leizer, Manuel Ottaviano, Mor Peleg, Konrad Śniatała, Aneta Lisowska, Szymon Wilk, Enea Parimbelli, Silvana Quaglini, Mimma Rizzo, Laura Deborah Locati, Annelies Boekhout, Lonneke V van de Poll-Franse, Sofie Wilgenhof

“…Mixed effects linear regression models were used to compare HRQoL between the 2 groups over time. …”
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Enhancing CO₂ selectivity in MOFs through a dual-ligand strategy: Experimental and theoretical insights by Amir Kazemi, Akram Karbalaee Hosseini, Mahyar Ashourzadeh Pordsari, Mohsen Tamtaji, Saber Keshavarz, Faranak Manteghi, Azadeh Tadjarodi, Ahad Ghaemi, Sohrab Rohani, William A. Goddard

“…These analyses were confirmed based on the Langmuir isotherm and Elovich kinetic models (R² > 0.95). Furthermore, DFT calculations revealed that IUST-4 exhibits the highest adsorption energy (-0.11 eV), outperforming IUST-2 (-0.06 eV) and IUST-3 (-0.05 eV). …”
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Protective role of ginsenoside Rg1 in the dynamic progression of liver injury to fibrosis: a preclinical meta-analysis by Lijuan Dan, Xiuyan Li, Shuanglan Chen, Xiaojie You, Dong Wang, Tianyuan Wang, Jia Li, Wenping Liu, Jie Mu, Quansheng Feng, Quansheng Feng

“…This study evaluated the efficacy and underlying mechanisms of ginsenoside Rg1 in animal models of liver injury and fibrosis, and providing a basis for future clinical investigation.MethodsA systematic review was conducted on preclinical studies published in PubMed, Web of Science, and Embase databases up to 1 August 2024, adhereing to rigorous quality standards. …”
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Genome-Wide Association Study of Bone Mineral Density in Korean Men by Ye Seul Bae, Sun-Wha Im, Mi So Kang, Jin Hee Kim, Soon Hang Lee, Be Long Cho, Jin Ho Park, You-Seon Nam, Ho-Young Son, San Deok Yang, Joohon Sung, Kwang Ho Oh, Jae Moon Yun, Jong Il Kim

“…Multivariate linear regression models were applied to adjust for age and body mass index interference. …”
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Cancer, genetic susceptibility and risk of coronary artery disease: A prospective study by Yidan Wang, Shan Zhong, Na Sun, Yunfei Wu, Jun Lyu, Minghui Piao, Wenbo Qu, Xueyu Wang, Wenjun Ni, Xia Gu, Tianshu Han, Jinwei Tian

“…CAD-PRS was categorized as low (lowest tertile), intermediate (tertile 2), and high (highest tertile). Adjusted Cox models assessed the joint and interaction effects of cancer status and CAD-PRS on CAD outcomes. …”
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A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children by Joana Llauradó-Pont, Nikos Stratakis, Giovanni Fiorito, Evangelos Handakas, Alexander Neumann, Henrique Barros, Anne Lise Brantsæter, Kiara Chang, Leda Chatzi, Janine F. Felix, Regina Grazuleviciene, Vincent W. V. Jaddoe, Marianna Karachaliou, Marion Lecorguillé, Carla Lopes, Christopher Millett, Rosemary R. C. McEachan, Eleni Papadopoulou, Remy Slama, Eszter P. Vamos, Paolo Vineis, Martine Vrijheid, John Wright, Trudy Voortman, Mariona Bustamante, Oliver Robinson, Camille Lassale

“…Associations were estimated within each cohort using robust linear regression models, adjusting for relevant covariates, followed by a meta-analysis of the resulting EWAS estimates. …”
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Longitudinal analysis of lifestyle risk factors, nutrition status and drivers of food choice among urban migrants in Ulaanbaatar, Mongolia, and Almaty, Kazakhstan: a formative stud... by Sabri Bromage, Shamil Tazhibayev, Xin Zhou, Chang Liu, Enkhtsetseg Tserenkhuu, Oksana Dolmatova, Munkhbat Khishignemekh, Leyla Musurepova, Wusigale, Soninkhishig Tsolmon, Enkhjargal Tsendjav, Davaasambuu Enkhmaa, Rajesh Kumar Rai, Bayarmaa Enkhbat, Bilige Menghe, Davaasambuu Ganmaa

“…Trends were analysed using mixed-effects models and qualitatively compared within and between cities. …”
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Saturated hydraulic conductivity and steady-state infiltration rate database for Brazilian soils by Marta Vasconcelos Ottoni, Wenceslau Geraldes Teixeira, Aline Mari Huf dos Reis, Letícia Guimarães Pimentel, Luciana Rodrigues Souza, Jackson Adriano Albuquerque, Valdinar Ferreira Melo, Karina Maria Vieira Cavalieri-Polizeli, José Miguel Reichert, João Herbert Moreira Viana, Ademir Fontana, Lucas de Castro Medrado, Glenio Guimarães Santos, Luís Gustavo Henriques do Amaral, Lúcia Helena Cunha dos Anjos, José Coelho de Araújo Filho, Silvio Barge Bhering, Gabrielle Fernandes de Brito, Pedro Gomes de Campos do Valle, Pablo Nieto Campos, Adriana Monteiro da Costa, Jean Dalmo de Oliveira Marques, Alba Leonor da Silva Martins, Michele Bruna de Souza do Nascimento, Norberto Cornejo Noronha, Ricardo Duarte de Oliveira, Jeane Cruz Portela, Milson Evaldo Serafim, Marlen Barros e Silva, Sueli Rodrigues, Wilk Sampaio de Almeida, Margareth Lopes de Moraes, Nilton Curi

“…The Ksat-SSIR-DB has enormous potential for developing and testing Ksat pedotransfer functions in Brazilian soils, serving as a reference source for different geoenvironmental applications and, in particular, for modeling land surface processes. It is open access and can be accessed at https://www.sgb.gov.br/ksat-ssir-dbbase-de-dados-de-condutividade-hidraulica-saturada-e-de-taxa-de-infiltracao-basica-emsolos-brasileiros, which also includes the python script for data analysis.…”
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How drinking motives mediate associations between sexual orientation and indicators of alcohol use – a study among young Swiss men by Matthias Wicki, Matthias Wicki, Simon Marmet, Joseph Studer, Joseph Studer, Kim Bloomfield, Kim Bloomfield, Kim Bloomfield, Gerhard Gmel, Gerhard Gmel, Gerhard Gmel, Gerhard Gmel

“…Structural equation modeling was used to test whether drinking motives mediated the associations between dummy-coded sexual orientation (with heterosexual men as the reference) and alcohol use indicators or AUD symptoms.ResultsMostly-heterosexual men exhibited higher scores on alcohol use indicators than heterosexual men, with almost full mediation through their drinking motives, specifically higher enhancement motives. …”
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Hierarchizing multi-scale environmental effects on agricultural pest population dynamics: a case study on the annual onset of Bactrocera dorsalis population growth in Senegalese or... by Caumette, Cécile, Diatta, Paterne, Piry, Sylvain, Chapuis, Marie-Pierre, Faye, Emile, Sigrist, Fabio, Martin, Olivier, Papaïx, Julien, Brévault, Thierry, Berthier, Karine

“…We then developed a flexible analysis pipeline centred on a recent machine learning algorithm, which allows the combination of gradient boosting and grouped random effects models or Gaussian processes, to hierarchize the effects of multi-scale environmental variables on the onset of annual BD population growth in orchards. …”
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Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia by Michael Marks, David Mabey, Ruth Canter, Elizabeth Allen, Charles Opondo, Jennifer Palmer, Iris Mosweu, Jacob Novignon, Sinéad Langan, Maria Zuurmond, Catherine Pitt, Stephen L Walker, Dorothy Yeboah-Manu, Tara Mtuy, Rachel L Pullan, Richard Phillips, Daniel Okyere, Anthony Ablordey, Samantha Owen, Portia Boakye Okyere, Kidist Bobosha, Katherine Halliday, Steve Walker, Galana Mamo Ayana, Rachel Pullan, Mirgissa Kaba, Tara B Mtuy, Yaw Amoako, Adwoa Asante-Poku, Abigail Agbanyo, Eric Koka, Joseph Timothy, Yohannes Hailemichael, Abebaw Yeshambel Alemu, Teklu Cherkose, Getachew Kebebew, Fikregabrail Aberra Kassa, Tedros Nigusse, Kibur Engedawork, Zenebu Begna, Abay Waday, Saba Lambert, Katherine Elizabeth Halliday, Endalamaw Gadisa, Vanessa Yardley, Collins Ahorlu, Anita Achiaa Gyekye, Emmanuel Afreh, Esther Amon, Abraham Kwabena Anang, Ruth Dede Tuwor, Giulia D’Odorico, Kibur Engidawork, Mehari Getaneh, Bernadette Morkporkpor, Emmanuel Narh, Dorcas Opai-Tetteh, Yohannes Michael, Amel Mohammed, Fewzia Shikur Mohammed, Shimelis Doni Nigusse, Maja Niksic, Edmond Okloo, Michael Oppong, Lucy Owusu, Ishaque Siam, Ingrid Sobel, Feleke Tilahum, Joseph Tuffour, Abay Woday, Abebaw Yeshambel, Adelaide Forkuo- Boadu, Derrick Kontoh, Jojo Cobbinah

“…Many policy actors felt that existing supply chain interventions, decentralised treatment approaches and community engagement initiatives for leprosy could also benefit CL, but others also warned against increasing care-seeking unless CL treatment could be provided on a scale commensurate with the large burden they perceived.Conclusion Our findings demonstrate significant gaps in the provision of care for skin NTDs within primary healthcare, very different health-seeking patterns for leprosy and CL, and a need to develop new models of care, especially for CL.…”
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Clinical depression prevalence and associated factors among adolescents with sickle cell anemia in dar es salaam, tanzania: a cross-sectional study by Linda Paul Athman, Agnes Jonathan, Fatima Musa, Honesta John Kipasika, Isihaka Mahawi, Florence Urio, Mwashungi Ally, Ritah Mutagonda, Lulu Chirande, Julie Makani, Emmanuel Balandya

“…Univariate and multivariate regression models were used to determine factors associated with clinical depression. …”
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Estimating the association between cigarette and e-cigarette use patterns and SARS-CoV-2 negative conversion time: retrospective online survey in China by Ying Xie, Yinghua Li, Zheng Su, Xueyan Han, Zhao Liu, Zhenxiao Huang, Anqi Cheng, Xinmei Zhou, Jinxuan Li, Rui Qin, Xiaowen Wei, Yi Liu, Xin Xia, Qingqing Song, Liang Zhao, Kian Fan Chung, Dan Xiao, Chen Wang

“…Multi-variable adjusted Cox proportional hazard models were used to compare the negative conversion time of SARS-CoV-2 across different cigarette and e-cigarette use patterns. …”
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Triglyceride lowering in patients with different severities of hypertriglyceridaemia-associated acute pancreatitis: secondary analysis of a multicentre, prospective cohort study by Xiaoling Li, Lin Gao, Xiang Luo, Wenjian Mao, Lu Ke, Xiaoyan Lai, Lingyan Fu, Yaolu Liu

“…The association between target-reaching and the primary outcome was modelled. Furthermore, subgroup analyses were conducted based on the disease severity of HTG-AP patients at enrolment.Results Overall, 413 patients were included for analysis, of whom 192 (46.5%) reached the target on day 3. …”
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Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

“…This study aimed to demonstrate the potential effect and mechanism of LTX-315 in PD-L1 inhibition-induced anti-pancreatic cancer immunity.Methods Both immunodeficient and immunocompetent mouse models were used to evaluate the therapeutic efficacy of monotherapy and combination therapy. …”
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Associations of linear growth and weight gain in the first 2 years with bone mass at 4 years of age in children in Dhaka, Bangladesh by Maimuna Gias, Huma Qamar, Farzana Fariha, Abdullah Al Mahmud, Prakesh Shah, Steven A Abrams, Daniel E Roth, Karen M O’Callaghan

“…Design: Associations between interval-specific growth parameters (cLAZ and cWAZ) and bone outcomes were estimated using linear regression models, adjusted for maternal, child and household characteristics. …”
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Genome-wide transcriptome analysis and drug target discovery reveal key genes and pathways in thyroid cancer metastasis by Minjing Zou, Amal Qattan, Monther Al-Alwan, Hazem Ghebeh, Naif Binjumah, Latifa Al-Haj, Khalid S. A. Khabar, Abdulmohsen Altaweel, Falah Almohanna, Abdullah M. Assiri, Abdelilah Aboussekhra, Ali S. Alzahrani, Ali S. Alzahrani, Yufei Shi

“…MethodsWe performed genome-wide transcriptome analysis comparing gene expression profile of metastatic thyroid cancer cells (Met) with primary tumor cells established from transgenic mouse models of papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), poorly differentiated thyroid cancer (PDTC), and anaplastic thyroid cancer (ATC).ResultsGenes involved in tumor microenvironment (TME), inflammation, and immune escape were significantly overexpressed in Met cells. …”
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