Tibial tubercle transfer SurgeRy and physiothErapy Versus physIotherapy only for chronic paTellofemorAL paIn: study protocol for a randomiSed controllEd trial (REVITALISE) by Myrthe P. F. van de Ven, Martin Ophey, Victor van de Graaf, Sebastiaan A. W. van de Groes, Marijn Sinkeldam, Charlotte H. W. Wijers, Sander Koëter

“…Between-group differences will be analysed using multivariable linear regression analysis, while longitudinal differences will be assessed with linear mixed models for repeated measures. The difference in direct medical costs will also be assessed. …”
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Real-world effectiveness of hemodialysis modalities: a retrospective cohort study by Yan Zhang, Anke Winter, Belén Alejos Ferreras, Paola Carioni, Otto Arkossy, Michael Anger, Robert Kossmann, Len A. Usvyat, Stefano Stuard, Franklin W. Maddux

“…Methods In this retrospective cohort study, we analyzed pseudonymized data from 85,117 adults receiving in-center care across NephroCare clinics in Europe, the Middle East, and Africa during 2019–2022. Cox regression models with KRT modality and coronavirus disease 2019 (COVID-19) status as time-varying covariates, and adjusted for multiple confounders, were used to estimate all-cause (primary) and cardiovascular (secondary) mortality. …”
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Discrete time measures versus trajectories of drinking frequency across adolescence as predictors of binge drinking in young adulthood: a longitudinal investigation by Marie-Pierre Sylvestre, Robert J Wellman, Marilyn N Ahun, Geetanjali Datta, Didier Jutras-Aswad, Jennifer O Loughlin

“…Objectives We compared discrete time measures with trajectories of adolescent drinking frequency as predictors of sustained binge drinking in young adulthood.Design Prospective longitudinal study.Setting 10 high schools in Montréal, Canada.Participants 1293 high-school students followed from mean (SD) age 12 (0.6) to 24 (0.7) years.Primary outcome measures Patterns of drinking frequency (self-reports every 3 months from ages 12 to 17) identified using group-based trajectory modelling. Sustained binge drinking was defined as binging monthly or more often at both ages 20 and 24.Analyses Using logistic regression, sustained binge drinking was regressed on trajectory group membership and on four discrete time measures (frequency of drinking at age 12; frequency of drinking at age 17; age at drinking onset; age at onset of drinking monthly or more often).Results We identified seven drinking trajectories: late triers (15.2%), decreasers (9.5%), late escalators (10.4%), early slow escalators (16.5%), steady drinkers (14.4%), early rapid escalators (15.8%) and early frequent drinkers (18.2%). …”
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Secondary Cancer after Androgen Deprivation Therapy in Prostate Cancer: A Nationwide Study by Jae Heon Kim, Gi Hwan Bae, Jaehun Jung, Tae Il Noh

“…Cox proportional hazard regression models were used to estimate adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of events. …”

La escritura borrada de las mujeres. Itinerarios lectores inclusivos y (re)construcción del canon poético / The erased writing of women. Inclusive reading itineraries and (re)const... by Remedios Sánchez-García, Pablo Aparicio-Durán

“…Abstract This article deals with the way in which patriarchal structures have silenced women's poetic discourse in spanish’s 20th century, perpetuating the secular models of tradition. The theoretical starting point shows how the literary canon has been constructed on the basis of history and the dominant ideology in order to promote its dissemination through the school canon reproduced in the didactic materials used in literary education. …”
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Association between atherogenic index of plasma and future risk of cardiovascular disease in individuals with cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide pros... by Gaoshu Zheng, Jijie Jin, Fei Wang, Qianrong Zheng, Jiaxin Shao, Jiangnan Yao, Pan Huang, Hao Zhou, Jianghua Zhou

“…Restricted cubic spline models (RCS) were used to explore the potential non-linear relationship between cumulative AIP and CVD risk at different CKM syndrome stages. …”
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Association of serum chloride levels with all-cause mortality among patients in surgical intensive care units: a retrospective analysis of the MIMIC-IV database by Quan Ma, Wei Tian, Kaifeng Wang, Bin Xu, Tianyu Lou

“…Analytical methods included Kaplan–Meier survival curves, Cox proportional hazards regression models, and Restricted Cubic Spline (RCS) analyses to delineate the relationship between serum chloride concentrations and patient outcomes. …”
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Predictive value of the New Zealand Early Warning Score for early mortality in low-acuity patients discharged at scene by paramedics: an observational study by Bridget Dicker, Verity Frances Todd, Tony Smith, Andy Swain, Graham Howie, Melanie Moylan, Aroha Brett

“…Of these, 41 406 had sufficient recorded data to calculate an NZEWS.Primary and secondary outcome(s) and measure(s) Binary logistic regression modelling was used to investigate the association between the NZEWS and adverse outcomes of reattendance within 48 hours, mortality within 2 days, mortality within 7 days and mortality within 30 days.Results An NZEWS greater than 0 was significantly associated with all adverse outcomes studied (p<0.01), compared with the reference group (NZEWS=0). …”
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Assessing the Uses, Benefits, and Limitations of Digital Technologies Used by Health Professionals in Supporting Obesity and Mental Health Communication: Scoping Review by Amanda Kearns, Anne Moorhead, Maurice Mulvenna, Raymond Bond

“…Psychologists, dietitians, social workers, and health coaches used digital tools to facilitate virtual appointments, diet and mental health monitoring, and motivational and educational support through group therapy, 1-on-1 sessions, and hybrid models. Benefits included enhanced access to care and engagement, personalized digital cognitive behavioral therapy, perceived stigma reduction, privacy, and improved physical health outcomes in weight reduction. …”
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A positive relationship between weight-adjusted waist index and non-alcoholic fatty liver disease: a study on US adolescents by Xiaoling Cui, Xiaoling Cui, Yize Huang, Luyang Kang, Lianxiu Han, Weijie Sun, Kexing Han, Yufeng Gao

“…BackgroundNon-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver condition in children, underscoring the urgent need for non-invasive markers for early detection in this population.MethodsWe utilized survey data from the National Health and Nutrition Examination Survey (NHANES) 2017–2020 regarding liver ultrasound transient elastography (LUTE) for the diagnosis of NAFLD (dependent variable), and used multiple logistic regression models to explore the association between weight-adjusted waist circumference index (WWI) and the prevalence of NAFLD in US adolescents. …”
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Serum Ferritin Levels in Pregnancy and Their Association with Gestational Diabetes Mellitus: A Prospective Longitudinal Study by Qin Z, Du Y, Wang Z, Qin X, Wu H, Yu X, Zhao C, Mo L, Huang B

“…Multiple stepwise regression models were used to assess the relationship between glucose levels and the risk factors.Results: SF levels decreased with increasing gestation in the study population. …”
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Mesalazine for People with Diverticular Disease: A Systematic Review of Randomized Controlled Trials by Andrea Iannone, Marinella Ruospo, Germaine Wong, Michele Barone, Mariabeatrice Principi, Alfredo Di Leo, Giovanni F. M. Strippoli

“…We estimated risk ratios (RR) for dichotomous outcomes (disease remission/recurrence, acute diverticulitis in symptomatic uncomplicated diverticular disease, need for surgery/hospitalization, all-cause/disease-related mortality, adverse events), mean differences (MD) or standardized MD (SMD) for continuous outcomes (quality of life, symptoms score, time to recurrence/remission), and their 95% confidence intervals (CI) using random-effects models. We quantified heterogeneity by Chi2 and I2 tests. …”
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A methodical approach for evaluating the variability of productivity and fruit quality in the genetic collections of strawberry (Fragaria × ananassa Duch.) by V. I. Lapshin, V. V. Yakovenko, S. N. Shcheglov, V. N. Podorojny

“…To this end, the mathematical models  of two- and three-factor analysis of variance and cluster  analysis using Ward’s method were employed. …”
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Efficacy and retention rate of secukinumab in psoriatic arthritis across different clinical phenotypes: insights from the Italian GISEA Registry by Giuseppe Lopalco, Maria Morrone, Fabiola Atzeni, Chiara Bazzani, Francesco Paolo Bianchi, Francesco Paolo Cantatore, Roberto Caporali, Antonio Carletto, Alberto Cauli, Maria Sole Chimenti, Sergio Colella, Fabrizio Conti, Addolorata Corrado, Ennio Giulio Favalli, Alberto Floris, Marco Fornaro, Rosario Foti, Roberta Foti, Elena Fracassi, Bruno Frediani, Stefano Gentileschi, Roberto Gorla, Elisa Gremese, Emanuela Praino, Roberta Ramonda, Cinzia Rotondo, Marco Sebastiani, Angelo Semeraro, Gianfranco Ferraccioli, Giovanni Lapadula, Florenzo Iannone

“…Adjusted hazard ratios (aHRs) for discontinuing SECU were determined using multivariate Cox regression models. Results: SECU survival at 24 months was 63.24%, significantly higher in mixed PsA compared to perPsA ( p  = 0.036). …”
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Community disaster exposure and first onset of depression: A panel analysis of nationally representative South African data, 2008-2017. by Andrew Tomita, Busisiwe P Ncama, Yoshan Moodley, Rashieda Davids, Jonathan K Burns, Tafadzwanashe Mabhaudhi, Albert T Modi, Rob Slotow

“…Risk of first depression onset between individuals exposed and unexposed to community disaster was measured, accounting for multiple disaster exposure over time by fitting generalized estimating equation (GEE) regression models. Data on the geographic location of disasters were obtained from the South African government gazette, and mapped with the government delineated SA-NIDS households' locations. …”
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Sugar-sweetened beverages, relative grip strength, and psychological symptoms among rural adolescents in western China: a cross-sectional study by Yanni Zhang, Jianping Xiong, Rong Sun, Guangxin Chai, Li Xiong

“…Non-parametric tests, t-tests, logistic regression analyses, and ordered logistic regression analyses of generalized linear models were used to analyze the associations of sugar-sweetened beverage consumption and relative grip strength with psychological symptoms in adolescents.ResultsThe proportions of adolescents with sugar-sweetened beverages consumption of <1 times/week, 2–4 times/week, and >4 times/week in rural areas of western China were 34.6, 52.7, and 12.7%, respectively. …”
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Comparative Analysis of γ-Cyclodextrin, Perilla Oil, and Their Inclusion Complexes on Liver Injury and Dyslipidemia Associated with Elevated Gastrointestinal 12-Hydroxylated Bile A... by Keisuke Yoshikiyo, Hidehisa Shimizu, Edward G. Nagato, Satoshi Ishizuka, Tatsuyuki Yamamoto

“…Furthermore, we recommend evaluating γ-CD safety in both healthy and pathological models and carefully selecting compounds co-ingested with γ-CD.…”
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Scientific virtual reality as a research tool in prehistoric archaeology: the case of Atxurra Cave (northern Spain) by Antonio Torres, Mª Ángeles Medina-Alcaide, Iñaki Intxaurbe, Olivia Rivero, Joseba Rios-Garaizar, Martin Arriolabengoa, Juan Francisco Ruiz-López, Diego Garate

“…The study included analysing both three-dimensional (3D) models of the cave, obtained through photogrammetry and laser scanning, and the lighting systems in the graphics engine ©Unreal Engine 5; this allowed the researchers to create an interactive VR environment that faithfully reflects the current state of scientific knowledge about the cavity. …”
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Shift from chronic to episodic migraine frequency in a long-term phase 3 study of galcanezumab by Hans-Christoph Diener, Kathleen A. Day, Sarah Lipsius, Sheena K. Aurora, Nada A. Hindiyeh, Holland C. Detke

“…Double-blind percentage comparisons versus placebo represent modeled estimates from raw rates. Results At baseline, patients had a mean of 19.4 migraine headache days per month (SD = 4.5) and 21.4 headache days per month (SD = 4.1). …”
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Associations of PM2.5 and its components with term preterm rupture of membranes: a retrospective study by Jiangxia Qin, Weiling Liu, Haidong Zou, Chong Zeng, Cifeng Gao, Weiqi Liu

“…Cox proportional hazards models were used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) to evaluate the associations of exposure to PM2.5 and its components with the risk of TPROM. …”
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