Tasquinimod suppresses tumor cell growth and bone resorption by targeting immunosuppressive myeloid cells and inhibiting c-MYC expression in multiple myeloma by Marie Törngren, Rong Fan, Eline Menu, Helena Eriksson, Karin Vanderkerken, Andrew Chantry, Hatice Satilmis, Niels Vandewalle, Emma Verheye, Philip Vlummens, Anke Maes, Catharina Muylaert, Elke De Bruyne, Holly Evans, Nathan De Beule, Dirk Hose, Ken Maes, Karine Breckpot, Kim De Veirman

“…The in vivo impact on immune cells (myeloid cell subsets, macrophages, dendritic cells), tumor load, survival and bone disease were elucidated using immunocompetent 5TMM models.Results Tasquinimod treatment significantly decreased myeloma cell proliferation and colony formation in vitro, associated with an inhibition of c-MYC and increased p27 expression. …”
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Predictors and Outcomes of Hematoma Expansion and Neurological Decline in Intracerebral Hemorrhage: A Multisite Mobile Stroke Unit Study by Asish K. Gulati, Tianwen Ma, Isaiah Rolle, Ryan Peterson, Bianca Pirlog, Justine Chen, Megan Heckathorn, Jonathan Ratcliff, Nicolas Bianchi, Carol Fleming, Michael Frankel, James Grotta, Ritvij Bowry, Stephanie Parker, William Hicks, Digvijaya Navalkele

“…Predictive factors were analyzed using multiple logistic regression models. Results Of the 55 patients who met the inclusion criteria, 27% experienced HE within the first 4 hours from last known well with the majority of HE occurring within the first 60 to120 minutes. …”
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Sacubitril/valsartan is associated with improvements in quality of life in adult congenital heart disease patients with systemic right ventricular failure by Philippine Kiès, Marieke Nederend, Ralph M.L. Neijenhuis, Anna E. van Groningen, Monique R.M. Jongbloed, Hubert W. Vliegen, J. Wouter Jukema, Anastasia D. Egorova

“…Linear mixed effects models were used to evaluate the medium-term changes in 12 QOL domains.Results Of 40 sRV failure patients initiated on sacubitril/valsartan, 35 completed the titration phase, and 31 filled in a total of 98 TAAQOL questionnaires (response rate 77.5%). …”
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Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review by Irfan Anjum, Ayesha Nasir, Faiza Naseer, Faiza Naseer, Ahsan Ibrahim, Bisma Rehman, Fawad Bashir, Qura Tul Ain

“…However, cyclophosphamide has been employed in developing animal models of interstitial cystitis in in vivo studies. …”
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Tumor CEMIP drives immune evasion of colorectal cancer via MHC-I internalization and degradation by Ying Zhu, Jiao Li, Tao Zhang, Lei Zhao, Min Jin, Jinghua Ren, Jing Tang, Haihong Wang, Zhenyu Lin, Qing Liang, Ruiqi Li, Biying Zhang, Qingling Hua, Guojie Xu, Jiayuan Chen, Lanqing Wang, Dejun Zhang, Dandan Yu

“…In addition, the effect of CEMIP on tumor growth and the antitumor efficacy of targeting CEMIP in combination with ICB therapy were evaluated in murine models of colorectal cancer.Results We reported that CEMIP specifically downregulated the expression of MHC-I on the surface of murine and human colon cancer cells, hindering the cytotoxicity of CD8+ T cells. …”
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Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort studyResearch in context by Safoora Gharibzadeh, Ash Routen, Cameron Razieh, Francesco Zaccardi, Claire Lawson, Clare Gillies, Simon Heller, Melanie Davies, Helen Atkins, Stephen C. Bain, Nazir L. Lone, Krisnah Poinasamy, Tunde Peto, Elizabeth Robertson, Bob Young, Desmond Johnston, Jennifer Quint, Jonathan Valabhji, Khalida Ismail, Michael Marks, Alex Horsley, Annemarie Docherty, Ewen Harrison, James Chalmers, Ling-Pei Ho, Betty Raman, Chris Brightling, Omer Elneima, Rachel Evans, Neil Greening, Victoria C. Harris, Linzy Houchen-Wolloff, Marco Sereno, Aarti Shikotra, Amisha Singapuri, Louise Wain, Claudia Langenberg, John Dennis, John Petrie, Naveed Sattar, Olivia Leavy, Mattew Richardson, Ruth M. Saunders, Anne McArdle, Hamish McASuley, Tom Yates, Kamlesh Khunti, C.E. Brightling, R.A. Evans, L.V. Wain, J.D. Chalmers, V.C. Harris, L.P. Ho, A. Horsley, M. Marks, K. Poinasamy, B. Raman, A. Shikotra, A. Singapuri, C.E. Brightling, R.A. Evans, L.V. Wain, R. Dowling, C. Edwardson, O. Elneima, S. Finney, N.J. Greening, B. Hargadon, V.C. Harris, L. Houchen--Wolloff, O.C. Leavy, H.J.C. McAuley, C. Overton, T. Plekhanova, R.M. Saunders, M. Sereno, A. Singapuri, A. Shikotra, C. Taylor, S. Terry, C. Tong, B. Zhao, D. Lomas, E. Sapey, C. Berry, C.E. Bolton, N. Brunskill, E.R. Chilvers, R. Djukanovic, Y. Ellis, D. Forton, N. French, J. George, N.A. Hanley, N. Hart, L. McGarvey, N. Maskell, H. McShane, M. Parkes, D. Peckham, P. Pfeffer, A. Sayer, A. Sheikh, A.A.R. Thompson, N. Williams, C.E. Brightling, W. Greenhalf, M.G. Semple, M. Ashworth, H.E. Hardwick, L. Lavelle-Langham, W. Reynolds, M. Sereno, R.M. Saunders, A. Singapuri, V. Shaw, A. Shikotra, B. Venson, L.V. Wain, A.B. Docherty, E.M. Harrison, A. Sheikh, J.K. Baillie, C.E. Brightling, L. Daines, R. Free, R.A. Evans, S. Kerr, O.C. Leavy, N.I. Lone, D. Lozano-Rojas, H.J.C. McAuley, K. Ntotsis, R. Pius, J. Quint, M. Richardson, M. Sereno, M. Thorpe, L.V. Wain, M. Halling-Brown, F. Gleeson, J. Jacob, S. Neubauer, B. Raman, S. Siddiqui, J.M. Wild, S. Aslani, G. Baxter, M. Beggs, C. Bloomfield, M.P. Cassar, A. Chiribiri, E. Cox, D.J. Cuthbertson, M. Halling-Brown, V.M. Ferreira, L. Finnigan, S. Francis, P. Jezzard, G.J. Kemp, H. Lamlum, E. Lukaschuk, C. Manisty, G.P. McCann, C. McCracken, K. McGlynn, R. Menke, C.A. Miller, A.J. Moss, T.E. Nichols, C. Nikolaidou, C. O'Brien, G. Ogbole, B. Rangelov, D.P. O'Regan, A. Pakzad, S. Piechnik, S. Plein, I. Propescu, A.A. Samat, L. Saunders, Z.B. Sanders, R. Steeds, T. Treibel, E.M. Tunnicliffe, M. Webster, J. Willoughby, J. Weir McCall, C. Xie, M. Xu, L.V. Wain, J.K. Baillie, H. Baxendale, C.E. Brightling, M. Brown, J.D. Chalmers, R.A. Evans, B. Gooptu, W. Greenhalf, H.E. Hardwick, R.G. Jenkins, D. Jones, I. Koychev, C. Langenberg, A. Lawrie, P.L. Molyneaux, A. Shikotra, J. Pearl, M. Ralser, N. Sattar, R.M. Saunders, J.T. Scott, T. Shaw, D. Thomas, D. Wilkinson, L.G. Heaney, A. De Soyza, D. Adeloye, C.E. Brightling, J.S. Brown, J. Busby, J.D. Chalmers, C. Echevarria, L. Daines, O. Elneima, R.A. Evans, J. Hurst, P. Novotny, C. Nicolaou, P. Pfeffer, K. Poinasamy, J. Quint, I. Rudan, E. Sapey, M. Shankar-Hari, A. Sheikh, S. Siddiqui, S. Walker, B. Zheng, J.R. Geddes, M. Hotopf, K. Abel, R. Ahmed, L. Allan, C. Armour, D. Baguley, D. Baldwin, C. Ballard, K. Bhui, G. Breen, K. Breeze, M. Broome, T. Brugha, E. Bullmore, D. Burn, F. Callard, J. Cavanagh, T. Chalder, D. Clark, A. David, B. Deakin, H. Dobson, B. Elliott, J. Evans, R.A. Evans, R. Francis, E. Guthrie, P. Harrison, M. Henderson, A. Hosseini, N. Huneke, M. Husain, T. Jackson, I. Jones, T. Kabir, P. Kitterick, A. Korszun, I. Koychev, J. Kwan, A. Lingford-Hughes, P. Mansoori, H. McAllister-Williams, K. McIvor, B. Michael, L. Milligan, R. Morriss, E. Mukaetova-Ladinska, K. Munro, A. Nevado-Holgado, T. Nicholson, C. Nicolaou, S. Paddick, C. Pariante, J. Pimm, K. Saunders, M. Sharpe, G. Simons, J.P. Taylor, R. Upthegrove, S. Wessely, G.P. McCann, S. Amoils, C. Antoniades, A. Banerjee, A. Bularga, C. Berry, P. Chowienczyk, J.P. Greenwood, A.D. Hughes, K. Khunti, C. Lawson, N.L. Mills, A.J. Moss, S. Neubauer, B. Raman, A.N. Sattar, C.L. Sudlow, M. Toshner, P.J.M. Openshaw, D. Altmann, J.K. Baillie, R. Batterham, H. Baxendale, N. Bishop, C.E. Brightling, P.C. Calder, C.M. Efstathiou, R.A. Evans, J.L. Heeney, T. Hussell, P. Klenerman, F. Liew, J.M. Lord, P. Moss, S.L. Rowland-Jones, W. Schwaeble, M.G. Semple, R.S. Thwaites, L. Turtle, L.V. Wain, S. Walmsley, D. Wraith, M.J. Rowland, A. Rostron, J.K. Baillie, B. Connolly, A.B. Docherty, N.I. Lone, D.F. McAuley, D. Parekh, A. Rostron, J. Simpson, C. Summers, R.G. Jenkins, J. Porter, R.J. Allen, R. Aul, J.K. Baillie, S. Barratt, P. Beirne, J. Blaikley, R.C. Chambers, N. Chaudhuri, C. Coleman, E. Denneny, L. Fabbri, P.M. George, M. Gibbons, F. Gleeson, B. Gooptu, B. Guillen Guio, I. Hall, N.A. Hanley, L.P. Ho, E. Hufton, J. Jacob, I. Jarrold, G. Jenkins, S. Johnson, M.G. Jones, S. Jones, F. Khan, P. Mehta, J. Mitchell, P.L. Molyneaux, J.E. Pearl, K. Piper Hanley, K. Poinasamy, J. Quint, D. Parekh, P. Rivera-Ortega, L.C. Saunders, M.G. Semple, J. Simpson, D. Smith, M. Spears, L.G. Spencer, S. Stanel, I. Stewart, A.A.R. Thompson, D. Thickett, R. Thwaites, L.V. Wain, S. Walker, S. Walsh, J.M. Wild, D.G. Wootton, L. Wright, S. Heller, M.J. Davies, H. Atkins, S. Bain, J. Dennis, K. Ismail, D. Johnston, P. Kar, K. Khunti, C. Langenberg, P. McArdle, A. McGovern, T. Peto, J. Petrie, E. Robertson, N. Sattar, K. Shah, J. Valabhji, B. Young, L.S. Howard, Mark Toshner, C. Berry, P. Chowienczyk, A. Lawrie, O.C. Leavy, J. Mitchell, J. Newman, L. Price, J. Quint, A. Reddy, J. Rossdale, N. Sattar, C. Sudlow, A.A.R. Thompson, J.M. Wild, M. Wilkins, S.J. Singh, W.D.-C. Man, J.M. Lord, N.J. Greening, T. Chalder, J.T. Scott, N. Armstrong, E. Baldry, M. Baldwin, N. Basu, M. Beadsworth, L. Bishop, C.E. Bolton, A. Briggs, M. Buch, G. Carson, J. Cavanagh, H. Chinoy, C. Dawson, E. Daynes, S. Defres, R.A. Evans, L. Gardiner, P. Greenhaff, S. Greenwood, M. Harvie, L. HOuchen-Wolloff, M. Husain, S. MacDonald, A. McArdle, H.J.C. McAuley, A. McMahon, M. McNarry, G. Mills, C. Nolan, K. O'Donnell, D. Parekh, Pimm, J. Sargent, L. Sigfrid, M. Steiner, D. Stensel, A.L. Tan, I. Vogiatzis, J. Whitney, D. Wilkinson, D. Wilson, M. Witham, D.G. Wootton, T. Yates, D. Thomas, N. Brunskill, S. Francis, S. Greenwood, C. Laing, K. Bramham, P. Chowdhury, A. Frankel, L. Lightstone, S. McAdoo, K. McCafferty, M. Ostermann, N. Selby, C. Sharpe, M. Willicombe, L. Houchen-Wolloff, J. Bunker, R. Gill, C. Hastie, R. Nathu, N. Rogers, N. Smith, A. Shaw, L. Armstrong, B. Hairsine, H. Henson, C. Kurasz, L. Shenton, S. Fairbairn, A. Dell, N. Hawkings, J. Haworth, M. Hoare, A. Lucey, V. Lewis, G. Mallison, H. Nassa, C. Pennington, A. Price, C. Price, A. Storrie, G. Willis, S. Young, P. Pfeffer, K. Chong-James, C. David, W.Y. James, C. Manisty, A. Martineau, O. Zongo, A. Sanderson, L.G. Heaney, C. Armour, V. Brown, T. Craig, S. Drain, B. King, N. Magee, D. McAulay, E. Major, L. McGarvey, J. McGinness, R. Stone, A. Haggar, A. Bolger, F. Davies, J. Lewis, A. Lloyd, R. Manley, E. McIvor, D. Menzies, K. Roberts, W. Saxon, D. Southern, C. Subbe, V. Whitehead, H. El-Taweel, J. Dawson, L. Robinson, D. Saralaya, L. Brear, K. Regan, K. Storton, J. Fuld, A. Bermperi, I. Cruz, K. Dempsey, A. Elmer, H. Jones, S. Jose, S. Marciniak, M. Parkes, C. Ribeiro, J. Taylor, M. Toshner, L. Watson, J. Weir McCall, J. Worsley, R. Sabit, L. Broad, A. Buttress, T. Evans, M. Haynes, L. Jones, L. Knibbs, A. McQueen, C. Oliver, K. Paradowski, J. Williams, E. Harris, C. Sampson, C. Lynch, E. Davies, C. Evenden, A. Hancock, K. Hancock, M. Rees, L. Roche, N. Stroud, T. Thomas-Woods, M. Babores, J. Bradley-Potts, M. Holland, N. Keenan, S. Shashaa, H. Wassall, E. Beranova, H. Weston, T. Cosier, L. Austin, J. Deery, T. Hazelton, C. Price, H. Ramos, R. Solly, S. Turney, L. Pearce, W. McCormick, S. Pugmire, W. Stoker, A. Wilson, N. Hart, L.A. Aguilar Jimenez, G. Arbane, S. Betts, K. Bisnauthsing, A. Dewar, P. Chowdhury, A. Chiribiri, A. Dewar, G. Kaltsakas, H. Kerslake, M.M. Magtoto, P. Marino, L.M. Martinez, C. O'Brien, M. Ostermann, J. Rossdale, T.S. Solano, E. Wynn, N. Williams, W. Storrar, M. Alvarez Corral, A. Arias, E. Bevan, D. Griffin, J. Martin, J. Owen, S. Payne, A. Prabhu, A. Reed, C. Wrey Brown, C. Lawson, T. Burdett, J. Featherstone, A. Layton, C. Mills, L. Stephenson, N. Easom, P. Atkin, K. Brindle, M.G. Crooks, K. Drury, R. Flockton, L. Holdsworth, A. Richards, D.L. Sykes, S. Thackray-Nocera, C. Wright, K.E. Lewis, A. Mohamed, G. Ross, S. Coetzee, K. Davies, R. Hughes, R. Loosley, L. O'Brien, Z. Omar, H. McGuinness, E. Perkins, J. Phipps, A. Taylor, H. Tench, R. Wolf-Roberts, L.S. Howard, O. Kon, D.C. Thomas, S. Anifowose, L. Burden, E. Calvelo, B. Card, C. Carr, E.R. Chilvers, D. Copeland, P. Cullinan, P. Daly, C.M. Efstathiou, L. Evison, T. Fayzan, H. Gordon, S. Haq, R.G. Jenkins, C. King, F. Liew, K. March, M. Mariveles, L. McLeavey, N. Mohamed, S. Moriera, U. Munawar, J. Nunag, U. Nwanguma, L. Orriss-Dib, D.P. O'Regan, A. Ross, M. Roy, E. Russell, K. Samuel, J. Schronce, N. Simpson, L. Tarusan, C. Wood, N. Yasmin, R. Reddy, A.-M. Guerdette, M. Hewitt, K. Warwick, S. White, A.M. Shah, C.J. Jolley, O. Adeyemi, R. Adrego, H. Assefa-Kebede, J. Breeze, M. Brown, S. Byrne, T. Chalder, A. Chiribiri, P. Dulawan, N. Hart, A. Hayday, A. Hoare, A. Knighton, M. Malim, C. O'Brien, S. Patale, I. Peralta, N. Powell, A. Ramos, K. Shevket, F. Speranza, A. Te, P. Beirne, A. Ashworth, J. Clarke, C. Coupland, M. Dalton, E. Wade, C. Favager, J. Greenwood, J. Glossop, L. Hall, T. Hardy, A. Humphries, J. Murira, D. Peckham, S. Plein, J. Rangeley, G. Saalmink, A.L. Tan, B. Whittam, N. Window, J. Woods, G. Coakley, D.G. Wootton, L. Turtle, L. Allerton, M. Beadsworth, A. Berridge, J. Brown, S. Cooper, A. Cross, D.J. Cuthbertson, S. Defres, S.L. Dobson, J. Earley, N. French, W. Greenhalf, H.E. Hardwick, K. Hainey, J. Hawkes, V. Highett, S. Kaprowska, G.J. Kemp, A.L. Key, S. Koprowska, L. Lavelle-Langham, N. Lewis-Burke, G. Madzamba, F. Malein, S. Marsh, C. Mears, L. Melling, M.J. Noonan, L. Poll, J. Pratt, E. Richardson, A. Rowe, M.G. Semple, V. Shaw, K.A. Tripp, B. Vinson, L.O. Wajero, S.A. Williams-Howard, J. Wyles, S.N. Diwanji, P. Papineni, S. Gurram, S. Quaid, G.F. Tiongson, E. Watson, B. Al-Sheklly, A. Horsley, C. Avram, P. Barran, J. Blaikely, M. Buch, N. Choudhury, D. Faluyi, T. Felton, T. Gorsuch, N.A. Hanley, T. Hussell, Z. Kausar, C.A. Miller, N. Odell, R. Osbourne, K. Piper Hanley, K. Radhakrishnan, S. Stockdale, D. Trivedi, A. De Soyza, C. Echevarria, A. Ayoub, J. Brown, G. Burns, G. Davies, H. Fisher, C. Francis, A. Greenhalgh, P. Hogarth, J. Hughes, K. Jiwa, G. Jones, G. MacGowan, D. Price, A. Sayer, J. Simpson, H. Tedd, S. Thomas, S. West, M. Witham, S. Wright, A. Young, M.J. McMahon, P. Neill, D. Anderson, H. Bayes, C. Berry, D. Grieve, I.B. McInnes, N. Basu, A. Brown, A. Dougherty, K. Fallon, L. Gilmour, K. Mangion, A. Morrow, K. Scott, R. Sykes, R. Touyz, E.K. Sage, F. Barrett, A. Donaldson, M. Patel, D. Bell, A. Brown, M. Brown, R. Hamil, K. Leitch, L. Macliver, J. Quigley, A. Smith, B. Welsh, G. Choudhury, J.K. Baillie, S. Clohisey, A. Deans, A.B. Docherty, J. Furniss, E.M. Harrison, S. Kelly, N.I. Lone, D.E. Newby, A. Sheikh, J.D. Chalmers, D. Connell, A. Elliott, C. Deas, J. George, S. Mohammed, J. Rowland, A.R. Solstice, D. Sutherland, C.J. Tee, N. Maskell, D. Arnold, S. Barrett, H. Adamali, A. Dipper, S. Dunn, A. Morley, L. Morrison, L. Stadon, S. Waterson, H. Welch, B. Jayaraman, T. Light, C.E. Bolton, P. Almeida, J. Bonnington, M. Chrystal, E. Cox, C. Dupont, S. Francis, P. Greenhaff, A. Gupta, L. Howard, W. Jang, S. Linford, L. Matthews, R. Needham, A. Nikolaidis, S. Prosper, K. Shaw, A.K. Thomas, L.P. Ho, N.M. Rahman, M. Ainsworth, A. Alamoudi, M. Beggs, A. Bates, A. Bloss, A. Burns, P. Carter, M. Cassar, K.M. Channon, J. Chen, F. Conneh, T. Dong, R.I. Evans, E. Fraser, X. Fu, J.R. Geddes, F. Gleeson, P. Harrison, M. Havinden-Williams, P. Jezzard, N. Kanellakis, I. Koychev, P. Kurupati, X. Li, E. Lukaschuk, K. McGlynn, H. McShane, C. Megson, K. Motohashi, S. Neubauer, D. Nicoll, G. Ogg, E. Pacpaco, M. Pavlides, Y. Peng, N. Petousi, J. Propescu, N. Rahman, B. Raman, M.J. Rowland, K. Saunders, M. Sharpe, N. Talbot, E. Tunnicliffe, W.D.-C. Man, B. Patel, R.E. Barker, D. Cristiano, N. Dormand, M. Gummadi, S. Kon, K. Liyanage, C.M. Nolan, S. Patel, O. Polgar, P. Shah, S.J. Singh, J.A. Walsh, J. Hurst, H. Jarvis, S. Mandal, S. Ahmad, S. Brill, L. Lim, D. Matila, O. Olaosebikan, C. Singh, M. Toshner, H. Baxendale, L. Garner, C. Johnson, J. Mackie, A. Michael, J. Pack, K. Paques, H. Parfrey, J. Parmar, N. Diar Bakerly, P. Dark, D. Evans, E. Hardy, A. Harvey, D. Holgate, S. Knight, N. Mairs, N. Majeed, L. McMorrow, J. Oxton, J. Pendlebury, C. Summersgill, R. Ugwuoke, S. Whittaker, W. Matimba-Mupaya, S. Strong-Sheldrake, S.L. Rowland-Jones, A.A.R. Thompson, J. Bagshaw, M. Begum, K. Birchall, R. Butcher, H. Carborn, F. Chan, K. Chapman, Y. Cheng, L. Chetham, C. Clark, Z. Coburn, J. Cole, M. Dixon, A. Fairman, J. Finnigan, L. Finnigan, H. Foot, D. Foote, A. Ford, R. Gregory, K. Harrington, L. Haslam, L. Hesselden, J. Hockridge, A. Holbourn, B. Holroyd-Hind, L. Holt, A. Howell, E. Hurditch, F. Ilyas, C. Jarman, A. Lawrie, E. Lee, J.-H. Lee, R. Lenagh, A. Lye, I. Macharia, M. Marshall, A. Mbuyisa, J. McNeill, S. Megson, J. Meiring, L. Milner, S. Misra, H. Newell, T. Newman, C. Norman, L. Nwafor, D. Pattenadk, M. Plowright, J. Porter, P. Ravencroft, C. Roddis, J. Rodger, P. Saunders, J. Sidebottom, J. Smith, L. Smith, N. Steele, G. Stephens, R. Stimpson, B. Thamu, N. Tinker, K. Turner, H. Turton, P. Wade, S. Walker, J. Watson, J.M. Wild, I. Wilson, A. Zawia, R. Aul, M. Ali, A. Dunleavy, D. Forton, N. Msimanga, M. Mencias, T. Samakomva, S. Siddique, J. Teixeira, V. Tavoukjian, J. Hutchinson, L. Allsop, K. Bennett, P. Buckley, M. Flynn, M. Gill, C. Goodwin, M. Greatorex, H. Gregory, C. Heeley, L. Holloway, M. Holmes, J. Kirk, W. Lovegrove, T.A. Sewell, S. Shelton, D. Sissons, K. Slack, S. Smith, D. Sowter, S. Turner, V. Whitworth, I. Wynter, L. Warburton, S. Painter, J. Tomlinson, C. Vickers, T. Wainwright, D. Redwood, J. Tilley, S. Palmer, G.A. Davies, L. Connor, A. Cook, T. Rees, F. Thaivalappil, C. Thomas, A. Butt, M. Coulding, H. Jones, S. Kilroy, J. McCormick, J. McIntosh, H. Savill, V. Turner, J. Vere, E. Fraile, J. Ugoji, S.S. Kon, H. Lota, G. Landers, M. Nasseri, S. Portukhay, A. Hormis, A. Daniels, J. Ingham, L. Zeidan, M. Chablani, L. Osborne, M. Marks, J.S. Brown, N. Ahwireng, B. Bang, D. Basire, R.C. Chambers, A. Checkley, R. Evans, M. Heightman, T. Hillman, J. Hurst, J. Jacob, S. Janes, R. Jastrub, M. Lipman, S. Logan, D. Lomas, M. Merida Morillas, A. Pakzad, H. Plant, J.C. Porter, K. Roy, E. Wall, B. Williams, M. Xu, D. Parekh, N. Ahmad Haider, C. Atkin, R. Baggott, M. Bates, A. Botkai, A. Casey, B. Cooper, J. Dasgin, K. Draxlbauer, N. Gautam, J. Hazeldine, T. Hiwot, S. Holden, K. Isaacs, T. Jackson, S. Johnson, V. Kamwa, D. Lewis, J.M. Lord, S. Madathil, C. McGhee, K. Mcgee, A. Neal, A. Newton Cox, J. Nyaboko, D. Parekh, Z. Peterkin, H. Qureshi, B. Rangelov, L. Ratcliffe, E. Sapey, J. Short, T. Soulsby, R. Steeds, J. Stockley, Z. Suleiman, T. Thompson, M. Ventura, S. Walder, C. Welch, D. Wilson, S. Yasmin, K.P. Yip, P. Beckett, C. Dickens, U. Nanda, C.E. Brightling, R.A. Evans, M. Aljaroof, N. Armstrong, H. Arnold, H. Aung, M. Bakali, M. Bakau, M. Baldwin, M. Bingham, M. Bourne, C. Bourne, N. Brunskill, P. Cairns, L. Carr, A. Charalambou, C. Christie, M.J. Davies, S. Diver, S. Edwards, C. Edwardson, O. Elneima, H. Evans, J. Finch, S. Glover, N. Goodman, B. Gootpu, N.J. Greening, K. Hadley, P. Haldar, B. Hargadon, V.C. Harris, L. Houchen-Wolloff, W. Ibrahim, L. Ingram, K. Khunti, A. Lea, D. Lee, D. Lozano-Rojas, G.P. McCann, H.J.C. McAuley, P. McCourt, T. Mcnally, G. Mills, A. Moss, W. Monteiro, K. Ntotsis, M. Pareek, S. Parker, A. Rowland, A. Prickett, I.N. Qureshi, R. Russell, N. Samani, M. Sereno, M. Sharma, A. Shikotra, S. Siddiqui, A. Singapuri, S.J. Singh, J. Skeemer, M. Soares, E. Stringer, T. Thornton, M. Tobin, E. Turner, L.V. Wain, T.J.C. Ward, F. Woodhead, J. Wormleighton, T. Yates, A. Yousuf, M.G. Jones, C. Childs, R. Djukanovic, S. Fletcher, M. Harvey, E. Marouzet, B. Marshall, R. Samuel, T. Sass, T. Wallis, H. Wheeler, R. Dharmagunawardena, E. Bright, P. Crisp, M. Stern, A. Wight, L. Bailey, A. Reddington, A. Ashish, J. Cooper, E. Robinson, A. Broadley, K. Howard, L. Barman, C. Brookes, K. Elliott, L. Griffiths, Z. Guy, D. Ionita, H. Redfearn, C. Sarginson, A. Turnbull, Y. Ellis, M. Marks, A. Briggs, K. Holmes, K. Poinasamy, S. Walker, M. Halling-Brown, G. Breen, M. Hotopf, K. Lewis, N. Williams

“…Differences in outcomes between diabetes status groups were largely consistent from 5 to 12-months. In regression models, differences at 5 and 12 months were attenuated after adjustment for BMI and presence of other long-term conditions. …”
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Socioeconomic characteristics and relapse-free and overall survival from childhood cancer – a nationwide study based on data from the Danish Childhood Cancer Registry by Fie Stegenborg, Mathilde Bek, Charlotte Nilsson, Line H. Pedersen, Thomas Scheike, Lisa Hjalgrim, Friederike Erdmann, Kjeld Schmiegelow, Pernille Bidstrup, Line Kenborg, Jeanette Winther, Hanne Larsen, Susanne Dalton

“…Cox proportional hazards models were used to estimate the association between SEP indicators and 5-year RFS and OS. …”
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Being a tree crop increases the odds of experiencing yield declines irrespective of pollinator dependence by Aizen, Marcelo A., Gleiser, Gabriela, Kitzberger, Thomas A., Milla, Ruben

“…Because pollinator dependence and plant growth form were partially correlated, we disentangled the effect of each of these two predictors using a series of generalized linear mixed models that evaluated direct and indirect associations. …”
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Consensus for Operating Room Multimodal Data Management: Identifying Research Priorities for Data-Driven Surgery by Alain Garcia Vazquez, MD, Juan Verde, MD, Ariosto Hernandez Lara, MD, Didier Mutter, MD, Lee Swanstrom, MD, 5G-OR Research Committee, 5G-OR Consensus Panel, Ariosto Hernandez Lara, Barbara Seeliger, Daniel Hashimoto, Deepak Alapatt, Joel Lavanchy, Juan Verde, Lise Lecointre, Pietro Mascagni, Pr.Danail Stoyanov, Didier Mutter, MD, Dirk Willhelm, MD, Pr.Gerald Fried, MD, Gretchen Jackson, MD, PhD, Jean-Paul Mazellier, PhD, Lee Swanstrom, MD, Pr.Lena Maier-Hein, Pr.Nicolas Padoy, PhD, Pr.Sascha Treskatsch, MD, Pr.Silvana Perretta, MD, PhD, Pr.Stefanie Speidel, Pr.Teodor Grantcharov, Annika Mareike Engel, BSc, MEng, Axel Boese, DrIng, Carla M. Pugh, MD, PhD, Cesare Hassan, Fabian Dietrich, PhD, Felix Nickel, MD, MME, Franziska Jurosch, MSc, Guido Beldi, MD, Henriette Hegermann, Dr, Johannes Horsch, Dipl-Ing, Julian Rosenkranz, Ing, MSc, Keno Sponheuer, DrMed, Luca Milone, MD, PhD, FACS, Nariaki Okamoto, MD, PhD, Patrick Seeling, PhD, Pedro Filipe Pereira Gouveia, MD, PhD, Roland Croner, Prof.Dr, Sandra Keller, PhD, Sharona B Ross, Taiga Wakabayashi, MD, Ph.D, Takeaki Ishizawa, MD, PhD, Takeshi Urade, MD, PhD, Thomas Schnelldorfer, MD, PhD, Thorge Lackner, MSc, and MEng

“…The roadmap prioritizes standardizing OR data formats, integrating OR data with patient information, ensuring regulatory compliance, standardizing surgical AI models, and securing data transfers in the next generation of wireless networks. …”
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Structural performance of lightweight fibre-reinforced oil palm shell concrete subjected to impact loadings under varying boundary conditions by Idris Ahmed Ja'e, Zakaria Che Muda, Agusril Syamsir, Chiemela Victor Amaechi, Hamad Almujibah, Ali.E.A. Elshekh, Maaz Osman Bashir, Abdulrazak H. Almaliki

“…The recorded experimental results for impact and crack behaviour under service and ultimate loading were analysed using response surface analysis. Regression models were developed to predict responses for specimens with up to 8 boundary conditions and 5 % PPF. …”
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Using machine learning to predict patients with polycystic ovary disease in Chinese women by Chen-Yu Wang, Dee Pei, Chun-Kai Wang, Jyun-Cheng Ke, Siou-Ting Lee, Ta-Wei Chu, Yao-Jen Liang

“…Random Forest (RF), stochastic gradient boosting (SGB), multivariate adaptive regression splines (MARS), extreme gradient boosting (XGBoost), and gradient boosting with categorical features support (CatBoost) are five Mach-L algorithms that were used. Models with lower estimation errors were better. Results: By using t-test, we found subjects with PCOS were younger, glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), γ-Glutamyl transferase (γ-GT), Triglyceride (TG), and educational levels were higher. …”
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Early Outcomes With Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement in Patients With Atrial Fibrillation by Shashank Shekhar, MD, Amar Krishnaswamy, MD, Grant Reed, MD, MSc, James Yun, MD, Rishi Puri, MD, PhD, Samir Kapadia, MD

“…Association of CPD use with adverse events was analyzed using multivariable logistic regression models. Results: Of 100,928 eligible TAVR patients with AF, CPD was used in 6.9% of patients with a mean age of 80 years. …”
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A critical review on enhancement and sustainability of energy systems: perspectives on thermo-economic and thermo-environmental analysis by Sunday O. Oyedepo, Mufutau A. Waheed, Fidelis I. Abam, Joseph O. Dirisu, Olusegun D. Samuel, Olusegun D. Samuel, Oluseyi O. Ajayi, Tosin Somorin, Abimbola P. I. Popoola, Oluwaseun Kilanko, Philip O. Babalola

“…Researchers and field engineers working on energy systems’ design, modeling, assessment, and performance optimization would find great value in this comprehensive review study.…”
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Improving Clinical Management of Diabetic Macular Edema: Insights from a Global Survey of Patients, Healthcare Providers, and Clinic Staff by Focke Ziemssen, Michelle Sylvanowicz, Winfried M. Amoaku, Tariq Aslam, Bora Eldem, Robert P. Finger, Richard P. Gale, Laurent Kodjikian, Jean-François Korobelnik, Xiaofeng Lin, Anat Loewenstein, Paul Mitchell, Moira Murphy, David R. Owens, Nick Parker, Ian Pearce, Francisco J. Rodríguez, Jude Stern, S. James Talks, David T. Wong, Tien Yin Wong, Jane Barratt

“…Methods We conducted a survey of patients with diabetic macular edema, providers, and clinic staff in 78 clinics across 24 countries on six continents, representing a diverse range of individuals, healthcare systems, settings, and reimbursement models. Surveys comprised a series of single- and multiple-response questions completed anonymously. …”
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Prediction of Soil Organic Carbon Content in <italic>Spartina alterniflora</italic> by Using UAV Multispectral and LiDAR Data by Jiannan He, Yongbin Zhang, Mingyue Liu, Lin Chen, Weidong Man, Hua Fang, Xiang Li, Xuan Yin, Jianping Liang, Wenke Bai, Fuping Li

“…The results show that the following. 1) The prediction accuracy is improved by classifying the data into three types: unlodging <italic>S. alterniflora</italic> (ULSA), lodging <italic>S. alterniflora</italic> (LSA), and mudflats. 2) XGBoost outperformed RF and SVM in accurately predicting SOC content, with <italic>R</italic>²; values of 0.743 for ULSA, 0.731 for LSA, and 0.705 for mudflats; 3) In the XGBoost models constructed for ULSA, LSA, and mudflats, spectral features contributed 75.7&#x0025;, 73.1&#x0025;, and 63.1&#x0025;, respectively, with the normalized difference vegetation index emerging as the most critical spectral feature. …”
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Elevated resting heart rate in adolescent men and risk of heart failure and cardiomyopathy by Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria Åberg, Kjell Torén, Margda Waern, N. David Åberg, Annika Rosengren

“…Risk estimates were calculated by Cox‐proportional hazards models while adjusting for potential confounders. …”
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Short-term costs of alcohol-associated hepatitis care in different clinical settings by Chi Mai Nguyen, Jing Su, Yang Li, Ryan Healey, Shihui Jiang, Jiangqiong Li, Naga Chalasani, Samer Gawrieh, Suthat Liangpunsakul, Wanzhu Tu

“…Comorbidities were identified using Elixhauser comorbidity software, and multivariable linear regression models were used to analyze medical costs. Results:. …”
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Extracellular viral microRNAs as biomarkers of virus infection in human cells by Cheryl Chan, Joanne Xin Yi Loh, Wei-Xiang Sin, Denise Bei Lin Teo, Nicholas Kwan Zen Tan, Chandramouli Nagarajan, Yunxin Chen, Francesca Lorraine Wei Inng Lim, Michael E. Birnbaum, Rohan B.H. Williams, Stacy L. Springs

“…Viral exmiR profiling of spent media from EBV- and HHV-8-reactivated B cell models revealed specific signatures of elevated EBV miR-BHRF1-2-3p and HHV-8 miR-K12-10a-3p, miR-K12-10b, and miR-K12-12-3p, respectively, during virus reactivation. …”
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Global, regional and national burdens of cardiovascular disease attributable to secondhand smoke from 1990–2019: an age-period-cohort analysis by Hong Jiang, Xiang-Bin Pan, Xiaofei Li, Shouzheng Wang, Zeye Liu, Peijian Wei, Fengwen Zhang, Wen-Bin Ou-yang

“…The distribution by sex revealed a slightly lower percentage of males (46.5%) than females (53.5%). Age-period-cohort models show overall global decline in CVD mortality due to secondhand smoke over 30 years, with regional, sex and subtype variations. …”
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Association between beta‐blocker atenolol use and prostate cancer upgrading in active surveillance1 by Ali H. Zahalka, Ethan Fram, Evan Garden, Lauren Howard, Emily Wiggins, Mustufa Babar, Jay Annam, Allison Reagan, Benjamin Eilender, Amanda deHoedt, Stephen J. Freedland, Ash Tewari, Kara L. Watts

“…Cox proportional hazard regression models were used to determine the associations between atenolol use and risk of upgrading with time, on a per‐examination basis. …”
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