Pluripotent stem cells from the perspective of developmental potential and their characteristics by In-Won Lee, Sang-Ki Baek, Yeon-Ji Lee, Tae-Suk Kim, Bo-Gyeong Seo, Cheol Hwangbo, Joon-Hee Lee

“…PSCs have tremendous potential in treating degenerative cells by generating the cells needed to replace damaged cells, which can also allow to generate specific cell types to study the mechanisms of the disease and create disease models that screen for potential drugs. However, if the proliferative capacity of PSCs is not controlled, there is a risk that tumors will form, as this can lead to uncontrolled growth in their proliferative capacity. …”
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Assessing the association between tourism and the alcohol urban environment in Barcelona: a cross-sectional study by Xisca Sureda, Manuel Franco, Susanna Puigcorbé, Joan R Villalbí, Marina Bosque-Prous, Ester Teixidó-Compañó, Montserrat Bartroli, Albert Espelt

“…To assess the relationship between rate ratios of elements of alcohol urban environment and tourism pressure, we calculated Spearman correlations and fitted Poisson regression models with robust error variance.Results The median densities obtained were of 8.18 alcohol premises and of 7.59 alcohol advertising and promotion elements visible from the public space per 1000 population. …”
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Age-specific abnormal glucose metabolism in HIV-positive people on antiviral therapy in China: a multicenter case-control study by Lijun Xu, Mengsha Chen, Chunhui Yan, Xiaofeng Li, Xiaoli Ni, Minghang Zhou, Weiwei Xu, Junfang Xu, Shigui Yang

“…The age-specific incidence of AGM was compared between the two groups. Poisson regression models were used to calculate the relative risk (RR) and its 95% confidence interval (CI) to assess the associations.Results Compared to PLWTH, PLWH had a higher rate of IR, IFG and DM, and a higher risk of developing IR (RR: 1.83; 95% CI: 1.60–2.10), IFG (RR: 3.87; 95% CI: 2.55–6.07), and DM (RR: 1.52; 95% CI: 1.09–2.12). …”
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Assessing the Dark Matter Content of Two Quasar Host Galaxies at z ∼ 6 through Gas Kinematics by Qinyue Fei, John D. Silverman, Seiji Fujimoto, Ran Wang, Luis C. Ho, Manuela Bischetti, Stefano Carniani, Michele Ginolfi, Gareth Jones, Roberto Maiolino, Wiphu Rujopakarn, N. M. Förster Schreiber, Juan M. Espejo Salcedo, L. L. Lee

“…Assuming that both galaxies exhibit disk rotation driven by the gravitational potential of the galaxy, we find that the best-fit disk models have a V _rot / σ  ≈ 2 and inferred circular velocities out to ∼6–8 kpc scales, well beyond the likely stellar distribution. …”
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Parents’ use of coercive and indulgent feeding practices for children with avid eating behaviour: an Ecological Momentary Assessment study by Abigail Pickard, Katie L. Edwards, Claire Farrow, Emma Haycraft, Moritz Herle, Clare Llewellyn, Helen Croker, Alice Kininmonth, Jacqueline Blissett

“…Over 10 days, participants completed EMA surveys via a mobile app to report on their mood, stress, feeding goals, and feeding practices during eating occasions. Multilevel modelling was used to assess how parental mood, goals, and the eating context (e.g., meal versus snack, public versus private setting) influenced feeding practices. …”
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Concentrations, composition profiles, and in vitro–in silico-based mixture risk assessment of bisphenol A and its analogs in plant-based foods by Chun-Hui Chiu, Shih-Han Sun, Yun-Jia Yao, Yi Chuang, Yu-Tsung Lee, Yi-Jun Lin

“…High-throughput toxicokinetic modeling was used to convert in vitro ToxCast estrogen receptor (ER) bioactive concentrations into human-equivalent points of departure (PODs), which were compared to PODs derived from animal studies and applied to assess mixture risks through the margin of exposure based on the common ER pathway. …”
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Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) and mortality among survivors of liver cirrhosis: a prospective cohort study by Danial Fotros, Azita Hekmatdoost, Fereshteh Pashayee-khamene, Sara Karimi, Saleheh Ahmadzadeh, Mehdi Saberifiroozi, Behzad Hatami, Zahra Yari

“…The study classified participants into three groups based on their FODMAPs consumption and assessed the risk of mortality using Cox proportional hazards regression models. Results Total FODMAPs intake was associated with increased overall mortality risk (T3 vs. …”
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Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis by Denis Poddubnyy, Torsten Diekhoff, Sevtap Tugce Ulas, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Juliane Greese, Katharina Ziegeler, Carolina Dominguez Aleixo, Maximilian Lindholz

“…Statistical analyses were done using (generalised) linear models, t-tests, χ2 tests and analysis of variances. …”
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Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma by Guiyu Kang, Hui Song, Lei Bo, Qi Liu, Qiang Li, Jingtan Li, Pan Pan, Jingting Wang, Yanfei Jia, Haiji Sun, Xiaoli Ma

“…Correlations of α5-nAChR, SOX2 and M2 phenotype tumor-associated macrophages (TAMs) were validated in mouse LUAD models and clinical samples. α5-nAChR expression was connected to SOX2 expression, smoking and bad prognosis of LUAD among clinical samples. …”
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Risk Factor Analysis in Vascular Access Complications for Hemodialysis Patients by Cristian Dan Roşu, Sorin Lucian Bolintineanu, Bogdan Florin Căpăstraru, Roxana Iacob, Emil Robert Stoicescu, Claudia Elena Petrea

“…Logistic regression modeling for thrombosis demonstrated moderate predictive accuracy (AUC: 0.64). …”
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Associations of lamplight exposure during sleep and sleep duration with attention-deficit/hyperactivity disorder among preschool children in China by Hui Jiang, Bin Yu, Yuanyang Liu, Hui Gao, Ruijuan Song, Siyue Tan, Shufen Han, Hui Zuo, Hui Zuo, Hui Zuo

“…Associations of exposure to light while sleeping and sleep duration with ADHD were examined by multivariable logistic regression models.ResultsThe overall prevalence of ADHD was 3.7%. …”
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Smoking behavior among Asian Americans during the initial phase of the COVID-19 pandemic: The influence of pandemic stressors and depression by Paula Lozano, Aven Peters, Alia Southworth, Yicklun Mo, Helen Lam, Fornessa T. Randal, Karen E. Kim

“…We conducted logistic regression models to estimate the relationship between exposure to the COVID-19 pandemic and current smoking. …”
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MUC2 expression modulates immune infiltration in colorectal cancer by Christophe M. Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad A. Al-Shaibi, Bernice Lo, Bernice Lo, Jessica Roelands, Davide Bedognetti, Davide Bedognetti, Wouter Hendrickx, Wouter Hendrickx

“…MUC2, a major component of the protective mucus layer in the gastrointestinal tract, has been implicated in CRC progression and immune response regulation.MethodIn this study, we sought to elucidate the relationship between MUC2 expression and immune infiltration within CRC using in vitro models involving two well-established cell lines, HT-29 and LS-174T. …”
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Predictive nomograms of repeat intrahepatic recurrence and overall survival after radiofrequency ablation of recurrent colorectal liver metastases by Ji-Chen Wang, Bin-Bin Jiang, Zhong-Yi Zhang, Yu-Hui Liu, Li-Jin Shao, Song Wang, Wei Yang, Wei Wu, Kun Yan

“…Potential prognostic factors associated with rIHR and OS, after RFA, were identified by using the competing-risks and Cox proportional hazard models, respectively, and were used to construct the nomogram. …”
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Pasting and Dough Rheological Properties of Ackee (Blighia sapida) Aril Flour: A Contribution to the Search for Wheat Flour Substitutes by Ramiro Torres-Gallo, Ricardo Durán, José García-Camargo, Oswaldo Morales, Diofanor Acevedo, Diego F. Tirado

“…Pasting properties (pasting temperature, peak viscosity, ease of cooking, swelling power, final viscosity at 50  °C, and thixotropy) were analyzed; and steady-state shear measurements were used to obtain consistency coefficients (K) and flow behavior indexes (n) after data was fitted to the Power Law and Herschel-Bulkley models. The gradual addition of the ackee aril flour fraction produced an increase in ash, fat, protein, and fiber content; while water and carbohydrate content showed the opposite behavior in the obtained composite flour. …”
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Groundwater for drinking and sustainable agriculture and public health hazards of nitrate: Developmental and sustainability implications for an arid aquifer system by Boualem Bouselsal, Adel Satouh, Johnbosco C. Egbueri, Mofreh A. Hashim, Ahmed A. Arafat, Prabhu Paramasivam, Ali Alzaed, Enas E. Hussein

“…The integration of the water quality index, health risk assessments, hydrogeochemical modeling, and GIS mapping provides a comprehensive framework for analyzing groundwater in arid regions under pressure from climate change and human activities. …”
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Exploring the process—structure–property relationship of nylon aramid 3D printed composites and parameter optimization using supervised machine learning techniques by Mohammed Raffic Noor Mohamed, Ganesh Babu Karuppiah, Dharani Kumar Selvan, Rajasekaran Saminathan, Shubham Sharma, Shashi Prakash Dwivedi, Sandeep Kumar, Mohamed Abbas, Dražan Kozak, Jasmina Lozanovic

“…The main goals of this research are to identify the significant input parameters using supervised machine learning methods and investigate the relationship between the process, structure, and properties of components created using fused deposition modeling utilizing nylon aramid composite filaments. …”
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Development of a Novel Co-Amorphous Curcumin and L-Arginine (1:2): Structural Characterization, Biological Activity and Pharmacokinetics by Jose Antonio Mancillas-Quiroz, Miriam del Carmen Carrasco-Portugal, Karina Mondragón-Vásquez, Juan Carlos Huerta-Cruz, Juan Rodríguez-Silverio, Leyanis Rodríguez-Vera, Juan Gerardo Reyes-García, Francisco Javier Flores-Murrieta, Jorge Guillermo Domínguez-Chávez, Héctor Isaac Rocha-González

“…<b>Methods</b>: Stability, solubility and structural characterization of the CAC12 were carried out by spectrometry techniques and in vitro assays, whereas the antinociceptive and anti-inflammatory effects were evaluated by CFA or carrageenan models. The mechanism of action was determined by cytokine quantification, and pharmacokinetic parameters were obtained through UPLC-MS/MS. …”
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Multifunctional dietary approach reduces intestinal inflammation in relation with changes in gut microbiota composition in subjects at cardiometabolic risk: the SINFONI project by Hugo Hornero-Ramirez, Arianne Morissette, Bruno Marcotte, Armelle Penhoat, Béryle Lecomte, Baptiste Panthu, Jacob Lessard Lord, Florence Thirion, Laurie Van-Den-Berghe, Emilie Blond, Chantal Simon, Cyrielle Caussy, Nathalie Feugier, Joël Doré, Philippe Sanoner, Alexandra Meynier, Yves Desjardins, Geneviève Pilon, André Marette, Patrice D. Cani, Martine Laville, Sophie Vinoy, Marie-Caroline Michalski, Julie-Anne Nazare

“…GM composition and metabolomic analysis were conducted. Mixed linear models were employed, integrating time (pre/post), treatment (MF/control), and sequence/period. …”
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The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits by T. I. Shashkova, D. D. Gorev, E. D. Pakhomov, A. S. Shadrina, S. Zh. Sharapov, Y. A. Tsepilov, L. C. Karssen, Y. S. Aulchenko

“…The GWAS-MAP platform and database can be used for studying the etiology of human diseases, building predictive risk models and finding potential biomarkers and therapeutic interventions. …”
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