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76681
Associations between surrogate insulin resistance indexes and osteoarthritis: NHANES 2003–2016
Published 2025-01-01“…This study included 14,715 adults from the National Health and Nutrition Examination Survey 2003–2016. Logistic regression models and restricted cubic spline were used to explore the relationship between surrogate IR indexes and OA. …”
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76682
Global, regional, and national burden of chronic obstructive pulmonary disease and its attributable risk factors from 1990 to 2021: an analysis for the Global Burden of Disease Stu...
Published 2025-01-01“…The relationship between COPD DALYs and the sociodemographic index (SDI) was estimated using Smoothing Splines models. Results Between 1990 and 2021, the changes were -1.46% (95% uncertainty interval [UI] -3.36% to 0.39%) in age-standardized prevalence, -37.12% (-43.37% to -27.68%) in mortality, and -36.98% (-42.37% to -28.54%) in DALYs rate. …”
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76683
Prognostic Impact of Adjuvant Immunotherapy in Patients With Resectable NSCLC After Neoadjuvant Chemoimmunotherapy: A Brief Report
Published 2025-01-01“…Unstratified Cox proportional hazards models were fitted to the subgroups. Results: In this multi-center cohort, 29.7% of patients (n = 130) achieved a pathologic complete response. …”
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76684
Clinicopathological characteristics and predictors of renal outcomes in diffuse crescentic glomerulonephritis : a retrospective single-center study from Western China
Published 2025-01-01“…Analytical methods included Cox regression models and Kaplan-Meier survival analysis to assess the data. …”
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76685
Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin
Published 2024-07-01“…Our results show that G6-CAR-NK92 cells can effectively kill various tumor cell lines in vitro on which ERp57 is induced or intrinsically expressed, and also exhibit potent antitumor effects in cancer cell-derived xenograft and patient-derived xenograft mouse models. Additionally, the antitumor activity of G6-CAR-NK92 cells is synergistically enhanced by the low-dose ICD-inducible drug OXP.Conclusion Collectively, our findings suggest that ERp57 can be leveraged as a new tumor antigen for CAR-NK targeting, and the resultant CAR-NK cells have the potential to be applied as a broad-spectrum immune cell therapy for various cancers by combining with ICD inducer drugs.…”
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76686
Association between weight-adjusted waist index and Hashimoto’s thyroiditis: insights from NHANES 2007–2012
Published 2025-01-01“…Analysis revealed a significant positive association between WWI and TPOAb levels (β: 4.78, 95% CI: 1.52, 8.05, p = 0.0041), which remained consistent across all multivariate linear regression models. In contrast, no significant correlation was found between WWI and TgAb levels after adjusting for covariates. …”
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76687
Lactate/albumin ratio as a prognostic biomarker for in-hospital mortality in pediatric patients with necrotizing enterocolitis
Published 2025-02-01“…The association between L/A and in-hospital mortality was assessed using logistic regression models. Results After inclusion and exclusion criteria, 100 NEC patients were included in the study, with 87 survivors and 13 deaths. …”
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76688
Methicillin-Resistant Coagulase-Negative Staphylococci Carriage is a Protective Factor of Methicillin-Resistant Staphylococcus Aureus Nasal Colonization in HIV-Infected Patients: A...
Published 2021-01-01“…The risk factors of MRSA colonization were analyzed using nonconditional logistic regression models. The phenotypic characteristics between MRSA and MRCoNS were compared by Chi-square test. …”
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76689
Delineating urban flooding when incorporating community stormwater knowledge
Published 2025-01-01“…Although there are currently models and frameworks to estimate stormwater runoff and predict urban flooding, there are often minimal observations to validate results due to the quick retreat of floodwaters from affected areas. …”
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76690
Assimilation efficiencies and elimination rates of silver, cadmium and zinc accumulated by trophic pathway in Gammarus fossarum
Published 2024-05-01“…Among these, the assimilation efficiency (AE) is an essential parameter for the implementation of models that take the trophic pathway into account. …”
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76691
Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning.
Published 2021-07-01“…Using boosted regression tree models with optimised hyperparameter selection, we estimated environmental suitability for onchocerciasis at the 5 × 5-km resolution across Africa. …”
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76692
Exploring the link between exposure to volatile organic chemicals and incidence of infertility:A cross-sectional study
Published 2025-01-01“…In order to comprehensively explore this relationship, various analytical models, including logistic regression, weighted quantile sum (WQS), and Bayesian kernel-machine regression (BKMR), were employed. …”
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76693
Downregulation of TNF-α/TNF-R1 Signals by AT-Lipoxin A4 May Be a Significant Mechanism of Attenuation in SAP-Associated Lung Injury
Published 2019-01-01“…We used western blot, polymerase chain reaction (PCR), and immunofluorescence to investigate the downregulation of TNF-α signals in cellular and animal models of SAP-associated lung injury following AT-Lipoxin A4 intervention. …”
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76694
Associations of prenatal urinary melamine, melamine analogues, and aromatic amines with gestational duration and fetal growth in the ECHO Cohort
Published 2025-01-01“…We estimated beta coefficients and 95% confidence intervals (CIs) using adjusted linear mixed models with continuous dilution-standardized concentrations (log2 transformed and scaled by interquartile range, IQR) or binary indicators for detection. …”
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76695
Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer
Published 2025-02-01“…We perform GµF of blood from orthotopic ovarian cancer mouse models and characterize the morphological features of scCTCs and cCTCs, and the expression of molecular markers for aggressiveness. …”
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76696
Reverberation Mapping of Two Variable Active Galactic Nuclei: Probing the Distinct Characteristics of the Inner and Outer Broad-line Regions
Published 2025-01-01“…We discuss these findings in the context of various BLR formation models, highlighting the importance of long-term, multiline RM campaigns in understanding of BLR structure and evolution. …”
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76697
Propensity score matched comparison of lymph node upstaging in early-stage lung cancer: open versus minimally invasive surgery with standardized lymphadenectomy
Published 2025-01-01“…We used logistic and Cox regression models to assess factors associated with upstaging, overall survival and progression-free survival, restrictively. …”
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76698
Investigating the potential of diffusion tensor atlases to generate anisotropic clinical tumor volumes in glioblastoma patients
Published 2025-01-01“…The degree of CTV anisotropy was controlled by the migration ratio, modeling tumor cell migration along the dominant white matter fiber direction extracted from DTI. …”
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76699
Carbon finance for forest resilience in California
Published 2025-01-01“…Employing a dynamic performance benchmark (DPB) framework, this study models the impacts of restoring resilience to high-risk forests via forest thinning followed by prescribed fire. …”
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76700
Shifting vegetation phenology in protected areas: A response to climate change
Published 2025-03-01“…This study makes a significant contribution to ecological informatics by integrating phenological metrics with climate models, thereby providing a scalable framework that is applicable to other regions facing similar climatic challenges.…”
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