Estimating population abundance and monitoring population trends of endangered, elusive subterranean mammals (Rodentia: Spalacinae: Nannospalax) using HRAMN methodology by Orsolya Moldován, Szabocs Balogh, Gábor Bakó, Zsolt Molnár, Gyula Szabó, András Molnár, Attila Németh

“…HRAMN involves collecting data through aerial surveys and producing high-resolution orthophoto mosaics and digital surface models. These data allowed the identification of blind mole rat mounds and the monitoring of population trends. …”
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Postoperative Morbidity and Mortality of Perforated Peptic Ulcer: Retrospective Cohort Study of Risk Factors among Black Africans in Côte d’Ivoire by Soro Kountele Gona, Mahassadi Kouamé Alassan, Koffi Gnangoran Marcellin, Kissi Ya Henriette, Coulibaly Adama, Assohoun Toussaint, Ehua Adjoba Manuela, Seu Gagon Sylvain, Afum-Adjei Awuah Anthony, Ehua Somian Francis

“…Variables were studied with Kaplan Meier and Cox proportional hazard models. Results. Among 161 patients operated on for PPU, 36 (27.5%) experienced complications and 31 (19.3%) died. …”
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CAFs-released exosomal CREB1 promotes cell progression and immune evasion in thyroid cancer via the positive regulation of CCL20 by Chen Zheng, Hu Hei, Yifei Zhai, Wenbo Gong, Runfang Zhang, Songtao Zhang

“…In vivo assays were performed by establishing xenograft models.Results CREB1 was highly expressed in TC. CREB1 positively interacted with CCL20 in TC. …”
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Association between transarterial chemoembolization refractoriness and prognosis in Chinese patients with hepatocellular carcinoma: a large retrospective cohort study by Qinxue Sun, Ziliang Wu, Xi Yin, Feng Li, Ri Liu

“…Kaplan-Meier survival analysis and multivariate Cox regression models were performed to evaluate the association between TACE-Refractoriness and OS. …”
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Novel metabolic prognostic score for predicting survival in patients with cancer by Jinyu Shi, Chenan Liu, Xin Zheng, Yue Chen, Heyang Zhang, Tong Liu, Qi Zhang, Li Deng, Hanping Shi

“…Finally, nomogram prognostic models and corresponding calculators were constructed and evaluated using the areas under the receiver operating characteristic curves (AUC), decision curve analysis (DCA), and calibration curves. …”
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ENO1 promotes PDAC progression by inhibiting CD8+ T cell infiltration through upregulating PD-L1 expression via HIF-1α signaling by Aziguli Tulamaiti, Shu-Yu Xiao, Yan Yang, Musitaba Mutailifu, Xia-Qing Li, Shi-Qi Yin, Hong-Tai Ma, Hong-Fei Yao, Lin-Li Yao, Li-Peng Hu, Jun Li, Shu-Heng Jiang, Zhi-Gang Zhang, Yan-Miao Huo, Dong-Xue Li, Xue-Li Zhang

“…In vivo, tumorigenesis was suppressed in mouse PDAC models by Eno1 knockdown. Flow cytometry analysis revealed that high expression of Eno1 altered the tumor immune microenvironment (TIME), particularly the impaired tumor infiltration and function of CD8+ T cells. …”
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Induced and Evoked Properties of Vibrotactile Adaptation in the Primary Somatosensory Cortex by Nicolaas A. J. Puts, Richard A. E. Edden, Suresh Muthukumaraswamy, Krish D. Singh, David J. McGonigle

“…Prolonged exposure to afferent stimulation (“adaptation”) can cause profound short-term changes in the responsiveness of cortical sensory neurons. While several models have been proposed that link adaptation to single-neuron dynamics, including GABAergic inhibition, the process is currently imperfectly understood at the whole-brain level in humans. …”
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Oncogenic RIT1 mutations confer ferroptosis vulnerability in lung adenocarcinoma by Ruilan Ma, Dian Yang, Peng Wang, Ziyi Zhang, Xuehong Zhang, Jialiang Song, Han Liu, Shuyan Liu, Yingqiu Zhang, Lijuan Zou

“…Lung adenocarcinoma NCI-H2110 cells containing endogenous RIT1 M90I mutation were susceptible to ferroptosis induction both in vitro and in vivo within xenograft models. Hence, our study unravels a novel aspect of RIT1 mutations in lung cancer and suggests ferroptosis induction as a potential therapeutic strategy to treat lung cancer patients carrying RIT1 mutations.…”
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Molecular Distributions and Abundances in the Binary-shaped Outflow of V Hya by Mark A. Siebert, Raghvendra Sahai, Samantha Scibelli, Anthony J. Remijan

“…Employing LTE and non-LTE models of emission from the DUDE, we estimate the abundance distributions for optically thin species, and compare them with prototypical carbon-rich AGB envelopes. …”
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SNAP and/or WIC Participation and Diet Quality in Mother-Child Dyads living in Greater Boston after Pandemic: A Mixed-Method Study by Thanit Vinitchagoon, Fang Fang Zhang, Rebecca C. Fauth, Erin Hennessy, Ana G. Maafs, Emma M. Browning, Christina D. Economos

“…Analysis of covariance using generalized linear models was employed to compare differences in Healthy Eating Index-2015 (HEI-2015) scores based on SNAP and/or WIC participation, and thematic analysis was used for coding themes. …”
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Thymus ad astra, or spaceflight-induced thymic involution by Wataru Muramatsu, Wataru Muramatsu, Maria Maryanovich, Maria Maryanovich, Maria Maryanovich, Taishin Akiyama, Taishin Akiyama, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis

“…Ground-based analogs simulating cosmic radiation and microgravity have been instrumental in elucidating mechanisms of thymic involution and its downstream effects on immunity. These models reveal that long-duration missions result in diminished naive T-cell output, leaving astronauts vulnerable to infections and possibly at high risk for developing neoplasia. …”
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Frequency of probable social media addiction and correlates of problematic social networking sites use in a sample of transgender adults by Katharina Grupp, Marco Blessmann, Hans-Helmut König, André Hajek

“…., awareness-raising, promotion of offline activities, using role models) could prove effective in this group, pending longitudinal research.…”
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An open-label study evaluating the safety and efficacy of AMO-01 for the treatment of seizures in Phelan-McDermid syndrome by Tess Levy, J. Lloyd Holder, Jr., Joseph P. Horrigan, Michael F. Snape, Alison McMorn, Christina Layton, Hailey Silver, Kate Friedman, Hannah Grosman, Slayton Underwood, Danielle Halpern, Jessica Zweifach, Paige M. Siper, Alexander Kolevzon

“…Converging lines of evidence in different experimental models indicate that the Ras-ERK pathway is implicated in the pathophysiology of seizure generation and neurobehavioral symptoms in PMS. …”
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Real-time non-destructive characterization of epoxy resin curing kinetics and mechanical response for enhanced manufacturing quality control by Gonzalo Seisdedos, Edgar Viamontes, Eduardo Salazar, Cristian Pantea, Eric S. Davis, Tommy Rockward, Benjamin Boesl

“…Finally, the curing kinetics were modeled using the Hill equation to better understand numerically the effect of varying stoichiometry in the curing process. …”
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Repurposing of phosphodiesterase-5 inhibitor sildenafil as a therapeutic agent to prevent gastric cancer growth through suppressing c-MYC stability for IL-6 transcription by Zhenzhan Zhang, Wuqing Huang, Donghua Huang, Zhou Xu, Qingfeng Xie, Xin Tan, Wenjun He, Weihao Yang, Guoxin Li, Jianguang Ji, Hao Liu

“…The anti-tumor effect and mechanism of the PDE5 inhibitor sildenafil were evaluated via using tumor cells, patient-derived tumor organoids and xenograft animal models in GC. A total of 161 Swedish GC patients from a nationwide population-based cohort who received post-diagnostic PDE5 inhibitors demonstrated lower cancer-specific mortality compared to the controls (HR = 0.66, 95% CI = 0.47-0.92, P = 0.016). …”
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Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for bone fragility by Sophie Debaenst, Tamara Jarayseh, Hanna De Saffel, Jan Willem Bek, Matthieu Boone, Ivan Josipovic, Pierre Kibleur, Ronald Y Kwon, Paul J Coucke, Andy Willaert

“…Next-generation sequencing confirmed high indel efficiency (mean 88%), mimicking stable knock-out models. Skeletal phenotyping at 7, 14, and 90 days post-fertilization (dpf) using microscopy, Alizarin Red S staining, and microCT was performed. …”
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A joint three-plane physics-constrained deep learning based polynomial fitting approach for MR electrical properties tomography by Kyu-Jin Jung, Thierry G. Meerbothe, Chuanjiang Cui, Mina Park, Cornelis A.T. van den Berg, Stefano Mandija, Dong-Hyun Kim

“…For the prediction of optimal fitting coefficients, three neural networks were separately trained on simulated heterogeneous brain models to predict optimal polynomial weighting parameters in three orthogonal planes. …”
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Long-term exposure to air pollution and lower respiratory infections in a large population-based adult cohort in Catalonia by Anna Alari, Otavio Ranzani, Carles Milà, Sergio Olmos, Xavier Basagaña, Payam Dadvand, Talita Duarte-Salles, Mark Nieuwenhuijsen, Cathryn Tonne

“…Air pollution exposure was assigned to individuaĺs residential address using locally-developed models. We characterized the concentration–response functions between long-term air pollution exposure and hospital admission for lower respiratory infections between 2015 and 2019. …”
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The effect of cacao bean extracts on the prevention of periodontal tissue breakdown in diabetic rats with orthodontic tooth movements by Nuzulul Hikmah, Mohamad Hidayat, Nur Permatasari, Aulanni'am Aulanni'am, Achmad Rudijanto

“…Conclusion: This study proved that CBE increased periodontal ligament synthesis and angiogenesis and decreased inflammatory response, thereby preventing periodontal tissue breakdown in diabetic rat models with tooth movement.…”
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Deconstructing the self and reshaping perceptions: An intensive whole-brain 7T MRI case study of the stages of insight during advanced investigative insight meditation by Winson F.Z. Yang, Avijit Chowdhury, Terje Sparby, Matthew D. Sacchet

“…We investigated the neurophenomenology of SoI in an intensively sampled adept meditator case study (4 hr 7T fMRI collected in 26 runs with concurrent phenomenology) who performed SoI and rated specific aspects of experience immediately thereafter. Linear mixed models and correlations were used to examine relations among the cortex, subcortex, brainstem, and cerebellum, and SoI phenomenology. …”
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