Epigenetic regulation of the nuclear genome associated with mitochondrial dysfunction in Leber’s hereditary optic neuropathy (LHON) by Aswathy P. Nair, Ambika Selvakumar, Janani Gopalarethinam, B. Abishek Kumar, Balachandar Vellingiri, Mohana Devi Subramaniam

“…In addition to primary mitochondrial DNA (mtDNA) mutations, there are also other environmental and epigenetic factors involved in the pathogenesis of LHON. …”
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Investigation of genetic structure of various cat breeds by using d-loop polimorphism in turkey by Elif Yılmaz Şahin, Vahdettin Altunok, Ercan Kurar

“…<b>Aim:</b> In this study, Mitochondrial DNA (mtDNA) polymorphism between the Van cats and the other cat breeds is revealed. …”
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Toxicity and Molecular Identification of Green Toadfish Lagocephalus lunaris Collected from Kyushu Coast, Japan by Yuji Nagashima, Takuya Matsumoto, Keisuke Kadoyama, Shoichiro Ishizaki, Makoto Terayama

“…Nucleotide sequence analysis of the 16S rRNA gene fragment of muscle mitochondrial DNA indicated that partial sequences of PCR products of four specimens were identical with that of L. lunaris. …”
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Phylogeography and hybridization of corvid birds in the Palearctic Region by A. P. Kryukov

“…Several genetic markers were unable to discriminate between pure carrion and hooded crows. Mitochondrial DNA sequences revealed no difference between carrion and hooded crows, but instead two diverged haplogroups within the eastern part of the distribution range of the carrion crow. …”
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Earthworm (Oligochaeta, Lumbricidae) intraspecific genetic variation and polyploidy by S. V. Shekhovtsov, Ye. A. Derzhinsky, E. V. Golovanova

“…In some cases, a single species may exhibit significant morphological variation, contain several races of different ploidy, and harbor multiple genetic lineages that display significant divergence in both nuclear and mitochondrial DNA. However, the relationship between ploidy races and genetic lineages in earthworms remains largely unexplored. …”
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Age-Dependent Loss of Mitochondrial Function in Epithelial Tissue Can Be Reversed by Coenzyme Q10 by Daniel Schniertshauer, Daniel Gebhard, Jörg Bergemann

“…The accumulation of reactive oxygen species damaged mitochondrial DNA and proteins can induce mitochondrial dysfunction within the electron transport chain. …”
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An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease by Brooke McMinn, Alicia L. Duval, Christie M. Sayes

“…Pathway 1 details the downstream consequences of oxidative stress, which include mitochondrial DNA damage, protein aggregation, and depolarization of the mitochondrial membrane. …”
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Preservation of Aquatic Environmental DNA Using Cationic Detergents by Viresh Thamke, Yared H. Bezabhe, Jana Jass, Per‐Erik Olsson

“…In this study, we assessed the effect of short‐ and long‐term water storage using three different cationic surfactants on the half‐life of zebrafish (Danio rerio) mitochondrial DNA (mtDNA) in mesocosm water. The surfactants used were benzalkonium chloride (BAC), cetylpyridinium chloride (CPC), and cetyltrimethylammonium bromide (CTAB). …”
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Toward the Development of the Trojan Female Technique in Pest Insects: Male‐Specific Influence of Mitochondrial Haplotype on Reproductive Output in the Seed Beetle Acanthoscelides... by Lea Vlajnić, Uroš Savković, Jelena Jović, Sanja Budečević, Biljana Stojković, Mirko Đorđević

“…The Trojan Female Technique, or TFT, is a method of the trans‐generational fertility‐based population control through the release of females that carry mitochondrial DNA mutations that negatively affect male, but not female, reproductive output. …”
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Trajectory of human migration: insights from autosomal and non-autosomal variant clustering patterns by Samayeta Sarkar Tuli, Joyatry Sarker, Mrinmoy Saha Roddur, Anik Biswas, Reefa Nawar, Tahmina Akter, Md. Wahid Murad, Abu Ashfaqur Sajib

“…Genetic variations present in the Y chromosomal and mitochondrial DNA provide the mole-cular basis to support the archeological and anthropological evidence that formulates the theories for describing the trajectory of human migration, which started almost 200,000 years ago out of Africa. …”
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What Drives Embryo Development? Chromosomal Normality or Mitochondria? by A. Bayram, I. Elkhatib, A. Arnanz, A. Linan, F. Ruiz, B. Lawrenz, H. M. Fatemi

“…Preimplantation genetic screening (PGS) and mitochondrial DNA (mtDNA) copy number were done using next generation sequencing (NGS). …”
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Preamplification Procedure for the Analysis of Ancient DNA Samples by Stefania Del Gaudio, Alessandra Cirillo, Giovanni Di Bernardo, Umberto Galderisi, Theodoros Thanassoulas, Theodoros Pitsios, Marilena Cipollaro

“…Real-time quantitative polymerase chain reaction (qPCR) was used to detect in the extracts the presence of PCR inhibitors and to estimate the DNA content. As mitochondrial DNA was detected in all samples, amplification of nuclear targets, as amelogenin and the polymorphism M470V of the transmembrane conductance regulator gene, yielded positive results in one case only. …”
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Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats by Lukáš Alán, Tomáš Olejár, Monika Cahová, Jaroslav Zelenka, Zuzana Berková, Magdalena Smětáková, František Saudek, Radoslav Matěj, Petr Ježek

“…Somatostatin analog octreotide completely blocked insulin secretion, impaired proliferation at low autocrine insulin, and decreased PPY secretion and mitochondrial DNA in INS-1E cells. In conclusion, in GK rats PI, significant local delta cell hyperplasia and suspected paracrine effect of somatostatin diminish beta cell viability and contribute to the deterioration of beta cell mass. …”
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Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression by Lili Hu, Na Wu, Jue Wang, Donghui Cai

“…Molecular docking was applied to further confirm the anti-MDD effects of PHE. The mitochondrial DNA (mtDNA) copy number, inflammatory cytokines and pathway-related mRNA expressions in PC12 cell were determined via quantitative PCR (qPCR) and enzyme-linked immunosorbent assay to verify our finding. …”
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A Genomic‐Based Workflow for eDNA Assay Development for a Critically Endangered Turtle, Myuchelys georgesi by Holly V. Nelson, Arthur Georges, Katherine A. Farquharson, Elspeth A. McLennan, Jane L. DeGabriel, Katherine Belov, Carolyn J. Hogg

“…ABSTRACT Environmental DNA (eDNA) analysis has become a popular conservation tool for detecting rare and elusive species. eDNA assays typically target mitochondrial DNA (mtDNA) due to its high copy number per cell and its ability to persist in the environment longer than nuclear DNA. …”
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Sinistroporomonorchis bolini n. sp. (Trematoda: Monorchiidae) from the Ocellated killifish, Floridichthys polyommus (Cyprinodontidae) in the Yucatán Peninsula, Mexico based on an i... by Leopoldo Andrade-Gómez, Juan F. Espínola-Novelo, Brenda Solórzano-García, Gerardo Pérez-Ponce de León

“…In addition, sequences of the 28S of large subunit of nuclear ribosomal RNA and cox1 of the mitochondrial DNA were obtained. Phylogenetic trees inferred from each dataset, placed all the specimens in a monophyletic clade, confirming that the isolates belonged to the same species. …”
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TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA by Shigeru Matsuda, Masunari Nakayama, Yura Do, Takashi Ishiuchi, Mikako Yagi, Sjoerd Wanrooij, Kazuto Nakada, Fan-Yan Wei, Kenji Ichiyanagi, Hiroyuki Sasaki, Dongchon Kang, Takehiro Yasukawa

“…Abstract Transcription of human mitochondrial DNA (mtDNA) begins from specific transcription promoters. …”
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Enhanced Engraftment of a Very Low-Dose Cord Blood Unit in an Adult Haemopoietic Transplant by Addition of Six Mismatched Viable Cord Units by Stephen J. Proctor, Catherine E. Chapman, Rachel Sharples, Helen L. Lucraft, Jennifer Wilkinson, Jane Conn, Peter G. Middleton

“…Early molecular remission of ALL was demonstrated using a novel PCR for a mitochondrial DNA mutation in the leukaemic clone. The cell dose of the matched cord was well below that recommended to engraft a 70 kg recipient. …”
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Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy by Xuwei Hou, Zhaohui Li, Yusuke Higashi, Patrice Delafontaine, Sergiy Sukhanov

“…We found that IGF-1 decreased cell senescence, prevented DNA telomere shortening, increased mitochondrial membrane potential, activated cytochrome C oxidase, and reduced mitochondrial DNA damage in long-term cultured (aged) aortic SMC, suggesting an antiaging effect. …”
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ATF4-mediated expression of NOXA is critical for necroptosis driven by glucose deprivation by Sasiprapa Sonkaew, Sasiprapa Sonkaew, Ruwaida Rajna, Yeon-Ji Park, Jiong Yan, Zhaoshan Liu, Siriporn Jitkaew, Zheng-Gang Liu, Swati Choksi

“…Our previous findings suggested that the mitochondrial protein, Noxa, may be involved in mediating the release of mitochondrial DNA during GD-induced ZBP1-dependent necroptotic pathway. …”
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