Treatment options for Leber hereditary optic neuropathy by I. Povilaitytė, R. Liutkevičienė

“…In about 70% of LHON cases three major mutations in mitochondrial DNA: 11778G>A/ND4, 3460G>A/ND1 and 14484T>C/ND6 are detected. …”
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Genetic parameters and parental and early-life effects of boar semen traits by Pedro Sá, Rodrigo M. Godinho, Marta Gòdia, Claudia A. Sevillano, Barbara Harlizius, Ole Madsen, Henk Bovenhuis

“…Early-life conditions can have an effect on later semen quantity and quality traits. Mitochondrial DNA and Y chromosome inheritances showed no effect on semen traits. …”
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CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis by Jianqiang Wu, Lixia Chen, Peijun Wen

“…WB, immunofluorescence, OCR detection, mitochondrial DNA assay, and cytosolic ATP assay were used to determine the relationship between CRIP1 and mitochondrial biogenesis, relationship between TFAM. …”
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Energy Metabolism and Lipidome Are Highly Regulated during Osteogenic Differentiation of Dental Follicle Cells by Oliver Pieles, Marcus Höring, Sadiyeh Adel, Torsten E. Reichert, Gerhard Liebisch, Christian Morsczeck

“…Moreover, the cellular state was more oxidized, and mitochondrial DNA was distinctly upregulated during the second half of differentiation. …”
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Sternal perforation and bifid ribs by Marie-Laure Fily, Eric Crubézy, Bertrand Ludes, Daniel Rougé, Béatrix Midant-Reynes

“…Amplification and sequencing of mitochondrial DNA suggested they were maternally related. …”
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Invasive mosquito species Aedes albopictus and Aedes aegypti on the Black Sea coast of the Caucasus: genetics (COI, ITS2), Wolbachia and Dirofilaria infections by E. V. Shaikevich, I. V. Patraman, A. S. Bogacheva, V. М. Rakova, O. Р. Zelya, L. A. Ganushkina

“…The study of nuclear and mitochondrial DNA revealed a low level of variability in the invasive mosquitoes Ae. albopictus and Ae. aegypti collected at different collection sites and in different years. …”
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Quantifying human genome parameters in aging by V. P. Volobaev, S. S. Kunizheva, L. I. Uralsky, D. A. Kupriyanova, E. I. Rogaev

“…A separate section of this review is devoted to the correlation of telomere length parameters with age, as well as the association of telomere length with the amount of mitochondrial DNA. In addition, we consider such a quantitative feature as the rate of accumulation of somatic mutations with aging in relation to the lifespan of living organisms. …”
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Neuroinflammatory Mechanisms of Mitochondrial Dysfunction and Neurodegeneration in Glaucoma by Joao N. Duarte

“…Mitochondrial damage has been linked to the accumulation of age-related mitochondrial DNA mutations and mitochondrial dysfunction, possibly through aberrant reactive oxygen species production and defective mitophagy. …”
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MIGRATIONS AS A CAUSE OF GENETIC HOMOGENEITY IN PACIFIC HERRING (CLUPEA PALLASII) FROM THE SEA OF OKHOTSK by V. V. Gorbachev

“…Analysis of the molecular variability of mitochondrial DNA (mtDNA) control region sequences has shown no differentiation between samples of spawning herring from various parts of the Okhotsk Sea (p > 0,05). …”
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L’enfant de Mezmaiskaya (Caucase) examiné dans une double perspective paléogénétique et paléoanthropologique by Véronique Barriel, Anne-Marie Tillier

“…The excellent bone preservation has allowed direct absolute dating and mitochondrial DNA extraction (Golovanova et al. 1999; Ovchinnikov et al. 2000). …”
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Protocol for the quantitative detection of mtDNA in the supernatants of activated human naive CD8+ T cells by Linlin Li, Jun Jin

“…We then detail procedures for supernatant collection and quantification using the absolute copy number of mitochondrial DNA (mtDNA) released into the supernatants from in-vitro-activated naive CD8+ T cells. …”
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Keiferia azapaensis sp. nov., the first representative of the New World micromoth genus Keiferia Busck (Lepidoptera, Gelechiidae) associated with a member of Asteraceae by Héctor Vargas

“…Despite this unusual host plant, a Maximum Likelihood analysis, based on mitochondrial DNA sequences, placed the new species within a well-supported Keiferia clade. …”
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Dysregulation of Mitochondrial Homeostasis in Cardiovascular Diseases by Ricky Patil, Hui Wang, Matthew Kazaleh, Gorav Ailawadi, Morgan Salmon

“…Redox imbalances can affect normal cellular processes including mitochondrial biogenesis, electrochemical equilibrium, and the regulation of mitochondrial DNA. In this review, we will discuss these imbalances and, in particular, the potential role of mitochondrial fusion, fission, biogenesis, and mitophagy in the context of vascular diseases and how the dysregulation of normal function might contribute to disease progression. …”
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A genetically confirmed hybrid between Natrix astreptophora and N. maura, two deeply divergent and ancient snake species by Andrea Criado-Flórez, Juan Pablo González de la Vega, Gabriel Martínez del Marmol, Uwe Fritz

“…Using two mitochondrial DNA fragments and six nuclear genes, we confirmed that a morphologically intermediate snake, captured in Andalusia, southwestern Spain (municipality of Huelva), was an F1 hybrid between a female Natrix astreptophora and a male N. maura. …”
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The Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes by Daria Diodato, Daniele Ghezzi, Valeria Tiranti

“…In addition, the biogenesis and maintenance of mitochondria, including mitochondrial DNA (mtDNA) replication, transcription, and translation, require nuclear-encoded genes. …”
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Leber hereditary optic neuropathy by R. Liutkevičienė, A. Sidaraitė, I. Kozlovskaja, V. Ašmonienė, N. Jurkutė

“… Leber hereditary optic neuropathy (LHON) is one of the most common inherited mitochondrial optic neuropathies, caused by mitochondrial DNA mutations. Three most common mutations, namely m.11778G>A, m.14484T>G, and m.3460G>A, account for the majority of LHON cases. …”
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De Novo Mutation of m.3243A>G together with m.16093T>C Associated with Atypical Clinical Features in a Pedigree with MIDD Syndrome by Zhixin Jiang, Yinan Zhang, Jingbin Yan, Fengwen Li, Xinqian Geng, Huijuan Lu, Xiaoer Wei, Yanmei Feng, Congrong Wang, Weiping Jia

“…In our study, we aimed to investigate the heredity way of the m.3243A>G among pedigrees with MIDD and discover novel mitochondrial DNA mutations related to atypical clinical phenotypes. …”
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The Inconsistency of the Algorithms of Jaro–Winkler and Needleman–Wunsch Applied to DNA Chain Similarity Results by Boris Melnikov

“…In this paper, we consider the distance matrices for the two mentioned algorithms, calculated for the mitochondrial DNA of 32 species of monkeys belonging to different genera. …”
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Mitochondrial Dysfunction as a Therapeutic Target in Diabetic Cardiomyopathy: Progress and Prospects by Feng Zhang, Zhuqing Li, Yanxin Wang, Chao Li, Chengzhi Lu

“…Recent studies have highlighted the crucial roles of mitochondrial dysfunction in the pathogenesis of DCM, including aspects such as glucose-lipid metabolic disorder, oxidative stress damage, calcium regulation disorder, respiratory chain uncoupling, kinetic imbalance, and mitochondrial DNA damage. Increasing numbers of targets and drugs are being identified to ameliorate mitochondrial dysfunction and consequently slow DCM progression. …”
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Leber's Hereditary Optic Neuropathy-Gene Therapy: From Benchtop to Bedside by Rajeshwari D. Koilkonda, John Guy

“…Leber's hereditary optic neuropathy (LHON) is a maternally transmitted disorder caused by point mutations in mitochondrial DNA (mtDNA). Most cases are due to mutations in genes encoding subunits of the NADH-ubiquinone oxidoreductase that is Complex I of the electron transport chain (ETC). …”
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