Showing 21 - 40 results of 140 for search '"mitochondrial DNA"', query time: 0.06s Refine Results
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    PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival by Chenxiao Yu, Marco Tigano, Erin L Seifert

    Published 2024-11-01
    “…Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of spurious poly-A tails by phosphodiesterase12 (PDE12). …”
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    Lower circulating mitochondrial DNA and increased mitokines suggest significant mitochondrial dysfunction in systemic lupus erythematosus with renal involvement by Camillo Ribi, Kristina Sundquist, Matthieu Halfon, Manuel Pascual, Ashfaque A Memon, Anna Hedelius

    Published 2025-02-01
    “…Mitochondrial dysfunction plays a significant role in SLE and may be assessed by measuring mitochondrial DNA (mtDNA) and cytokines reflecting mitochondrial stress (mitokines). …”
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    β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy by Yihui Huo, Taiyu Shen, Tianyin Feng, Moli Li, Wanli Zhao, Juan J. Loor, Ben Aernouts, Androniki Psifidi, Chuang Xu

    Published 2025-02-01
    “…Recent research has linked cytosolic mitochondrial DNA (mtDNA) with chronic aseptic inflammation by activating the cGAS-STING pathway during metabolic disorders, while autophagy activation effectively reverses this process. …”
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    Mitochondrial DNA from endothelial cells activated the cGAS-STING pathway and regulated pyroptosis in lung ischaemia reperfusion injury after lung transplantation by Ying-nan Ju, Hu Li, Zi-peng Zhuo, Qing Yang, Wei Gao

    Published 2025-01-01
    “…Endothelial cells were subjected to hypoxemia and reoxygenation and treated with inhibitors of cGAS and STING. Mitochondrial DNA (mtDNA), the cGAS-STING axis and cytokine levels in cells, cellular activity and death were evaluated. …”
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