Potential pharmacological effect of Quercetin Phytosome™ in the management of hyperuricemia: results from real-life clinical studies by Francesco Di Pierro, Francesco Di Pierro, Francesco Di Pierro, Fazle Rabbani, Meherullah Tareen, Roohi Nigar, Amjad Khan, Nicola Zerbinati, Maria L. Tanda, Massimiliano Cazzaniga, Alexander Bertuccioli, Alexander Bertuccioli, Paolo Falasca, Gabriele Damiani, Nicola Villanova

“…QP was well tolerated across all cohorts, with minimal, transient side effects.ConclusionQP supplementation demonstrates a significant hypouricemic effect. …”
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Analyzing power errors in the optical pumping system of atomic spin comagnetometers by Jiale QUAN, Ye LIU, Longyan MA, Wenfeng FAN, Wei QUAN

“…This implies that slow drifts or fluctuations in pumping power can directly affect the long-term stability of the comagnetometer, which is critical for applications requiring minimal drift over time. However, when the power error frequency is lower than the electron Larmor frequency, the response amplitude decreases because of the slower response time of the noble gas atoms, which partially suppresses the impact of the power error. …”
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Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE by Metin Yesiltepe, Tao Yin, Marc Tambini, Hanmei Bao, Meixia Pan, Cristina d’Abramo, Luca Giliberto, Xianlin Han, Luciano D’Adamio

“…These rats also exhibited elevated levels of phosphatidylglycerol, phosphatidylserine, phosphatidylethanolamine, sphingomyelin, and lysophosphatidylcholine. Minimal differences in lipid profiles between APOE3 hAβ and APOE4 hAβ rats reflect findings from mouse models. …”
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Perbandingan aspek ekologi dan karakteristik bulubabi Tripneustes gratilla pada lokasi berbeda by , Tasruddin, , Aonurafiq

“…Penelitian tentang bulubabi untuk budidaya masih minim dilakukan karena ketersediaan benih. Penelitian bertujuan membandingkan karakteristik aspek ekologis, sumber pakan, diameter, berat tubuh, berat gonad, indeks gonad, survival growth rate dan tingkat kelangsungan hidup bulubabi diperairan Pelabuhan Tanjung, Tanjung Tuis, Kilongan permai, Biak, dan Bolii.  …”
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Variations in vitamin D status among Chinese children aged 1–6 years during the COVID-19 pandemic by Yongfeng Qiao, Xiaoqin Wang, Yanfen Ma, Jian Hu

“…COVID-19-related restrictions minimally affected children’s 25(OH)D concentrations, revealing the nutritional implications of the pandemic.…”
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Physics-Informed Neural Networks for Modal Wave Field Predictions in 3D Room Acoustics by Stefan Schoder

“…PINNs are appealing since they can efficiently integrate a partial differential equation and experimental data by minimizing a loss function. However, a previous study experienced limitations in acoustics regarding the source term. …”
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Warm and humid environment induces gut microbiota dysbiosis and bacterial translocation leading to inflammatory state and promotes proliferation and biofilm formation of certain ba... by Yinrui Guo, Jianlang He, Shaojie Li, Shiqi Zou, Haiting Zhang, Xin Yang, Jian Wang

“…TNF-α specifically enhanced biofilm formation in microorganism like C. albicans and Staphylococcus aureus, with minimal effect on beneficial bacteria like Lacticaseibacillus paracasei and Lactiplantibacillus plantarum in the tested conditions. …”
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Idiopathic Retroperitoneal Fibrosis-Related Hydronephrosis: Evaluation of Comprehensive Management and Prediction of Inflammatory Markers for Stent-Free Outcomes by Huang Z, Liu Y, Xiao Y, Hu H, Xu T

“…Elevated inflammatory markers (IgG and CRP) at the initial iRPF diagnosis and IgG, CRP, and erythrocyte sedimentationrate (ESR) variations associated with hydronephrosis outcomes.Plain Language Summary: The 24-month scale might guide the decision of final removal.Elevated inflammatory markers (IgG and CRP) at initial iRPF diagnosis and IgG, CRP, and ESR decreasing during the treatment course could predict hydronephrosis remission and stent-free outcomes.Alternative treatments, such as immunosuppressants other than corticosteroids, rather than longer stent indwelling could be recommended for patients with minimal possibility of hydronephrosis remission.Keywords: idiopathic retroperitoneal fibrosis, hydronephrosis, ureteral stent, immunosuppressant medications, stent-free outcome…”
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Prediction and Mapping of Soil Total Nitrogen Using GF-5 Image Based on Machine Learning Optimization Modeling by LIU Liqi, WEI Guangyuan, ZHOU Ping

“…The spectra extracted from GF-5 imagery were generally quite similar to ground-measured spectral data, despite some noise, which had a minimal overall impact.[Conclusions]This study demonstrates the clear feasibility of using GF-5 satellite hyperspectral remote sensing data and machine learning algorithm for large-scale quantitative detection and visualization analysis of soil TN content. …”
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Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer by Bin Han, Fang-yuan Mao, Yong-liang Zhao, Yi-pin Lv, Yong-sheng Teng, Mubing Duan, Weisan Chen, Ping Cheng, Ting-ting Wang, Zhong-yuan Liang, Jin-yu Zhang, Yu-gang Liu, Gang Guo, Quan-ming Zou, Yuan Zhuang, Liu-sheng Peng

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The effect of irrigation practice and water consumption using aqua-crop by M.D. Teweldebrihan, M.O. Dinka

“…By doing so, they can determine the most effective irrigation strategies that optimize harvest while minimizing water consumption. This aspect holds particular significance in regions facing water scarcity.…”
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Effectiveness of Massive Open Online Course on Risk Communication Knowledge in Global Health Emergencies Among Nurses by Khin Thandar Aung, Rafiza Abdul Razak, Muhammad Fadli Zulkafley

“…Massive Open Online Courses (MOOCs) have transformed education. The minimal usage of MOOCs in nursing education reveals a lack of continuous healthcare professional development. …”
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Multiplex Bead Array Assay for Detection of 25 Soluble Cytokines in Blister Fluid of Patients with Complex Regional Pain Syndrome Type 1

“…The use of a multiplex-25 bead array cytokine assay and Luminex technology enabled simultaneous measurement of representative (1) proinflammatory cytokines such as GM-CSF, IL-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, IL-1RA, IL-6, IL-8, and TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math>; (2) Th1/Th2 distinguishing cytokines IFN-<mml:math alttext="$gamma $"> <mml:mi>&#x03B3;</mml:mi> </mml:math>, IL-2, IL-2R, IL-4, IL-5, and IL-10; (3) nonspecific acting cytokines IFN-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, IL-7, IL-12p40/p70, IL-13, IL-15, and IL-17; and (4) chemokines eotaxin, IP-10, MCP-1, MIP-1<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, MIP-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math>, MIG, and RANTES. Although minimal detection levels are significantly higher in the bead array system than those in common ELISA assays, in blister fluid, IL-1RA, IL-6, IL-8, TNF-<mml:math alttext="$alpha $"> <mml:mi>&#x03B1;</mml:mi> </mml:math>, IL-12p40/p70, MCP-1, and MIP-1<mml:math alttext="$eta $"> <mml:mi>&#x03B2;</mml:mi> </mml:math> were detectable and increased in CRPS1 affected extremities. …”
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Unequal ageing: the quality of life of senior citizens in the EU before and after COVID-19. A multidimensional approach by Elżbieta Roszko-Wójtowicz, Klaudia Przybysz, Agnieszka Stanimir

“…Countries such as Sweden and Germany reported gains in health, financial stability, and social relations, largely due to strong social policies and robust healthcare systems.Eastern Europe: Seniors in Eastern European countries, including Romania and Bulgaria, continued to face substantial challenges, with minimal improvements in quality of life. Economic instability, limited access to healthcare, and weaker social security systems were identified as key contributors to this stagnation.Impact of COVID-19: the pandemic exacerbated existing inequalities, particularly in the domains of social relations and finances. …”
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Analysis and comparison of the trends in burden of spinal cord injury in China and worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021 by Hao Qin, Yuhang Diao, Mingyu Hao, Zhitan Wang, Minghao Xie, Xiaojun Hu, Tao Zhu

“…Although the ASPR and ASIR for SCI are predicted to show a downward trend over the next 15 years, policy makers should continue to consider interventions to minimize the risk.…”
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Improving the adoption of a school-based nutrition program: findings from a collaborative network of randomised trials by Courtney Barnes, Rachel Sutherland, Lisa Janssen, Jannah Jones, Katie Robertson, Justine Gowland-Ella, Nicola Kerr, Aimee Mitchell, Karen Gillham, Alison L. Brown, Luke Wolfenden

“…Schools were randomised to either a high intensity (various implementation strategies), or a business as usual (minimal support) group. Measures and data collection processes were harmonised across the three trials to provide individual school-level data for planned pooled analyses. …”
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Bibliometric analysis of laryngeal cancer treatment literature (2003–2023) by Yan Zhao, Jiancheng Xue

“…An impending surge in research is driven by investigations into biomarkers, microenvironmental genetic mechanisms, alternatives to systemic chemotherapy, minimally invasive surgery, and herbal medicine explorations.…”
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The initial results of using brolucizumab (Beovu®), an angiogenesis inhibitor, for choroidal neovascularization in patients with age-related macular degeneration by N.S. Zhayvoronok, O.V. Kolenko, L.P. Danilova, E.L. Sorokin

“…In all patients after three injections the minimal values of CRT were reported: they decreased from 298 (284; 302) to 268 (263; 270) µm. …”
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Development and validation of a prediction model for coronary heart disease risk in depressed patients aged 20 years and older using machine learning algorithms by Yicheng Wang, Yicheng Wang, Yicheng Wang, Chuan-Yang Wu, Hui-Xian Fu, Jian-Cheng Zhang, Jian-Cheng Zhang, Jian-Cheng Zhang

“…Calibration curves indicated high congruence between observed and predicted odds, with minimal Brier scores of 0.026 and 0.021 for the training, respectively, reinforcing the model's ability to discriminate. …”
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Modeling Portfolio Optimization based on behavioral Preferences and Investor’s Memory by vahideh mousavi kakhki, Sanaz Khatabi

“…Traditional optimization models, such as Markowitz's Mean-Variance model, aim to maximize expected returns while minimizing risk. However, these models often fail to capture the complexities of real-world investment decisions, which are often influenced by behavioral factors. …”
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