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Mutational analysis of the yeast TRAPP subunit Trs20p identifies roles in endocytic recycling and sporulation.
Published 2012-01-01“…The role of Trs20p, which is essential for viability and a component of all three complexes, and how it might function within each TRAPP complex, has not been clarified to date. …”
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Analyzing an Unconventional Success Story Chick-fil-A Fast Food Restaurants in the USA
Published 2022-01-01“…This paper attempts what previous academic research has not: a thorough analysis of Chick-fil-A’s practices and policies, looking at how they might function as “success factors” and how the company has turned apparent disadvantages into advantages. …”
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Approaches to Village Reality of the Institute Graduate Writers (1950–1960)
Published 2021-12-01“…This endeavor sought to compensate for the absence from the villages of an industrial proletariat that might function as a revolutionary political subject with elements of conflict. …”
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4
I Go by The Name: The Naming of Indonesian Pop Singers’ Stage Names in Perspectives of Charactonym
Published 2025-07-01“…We argue that stage names might function as a charactonym in which the singers play a different character than they are in the real world. …”
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SIRT3 functions as a tumor suppressor in hepatocellular carcinoma
Published 2017-03-01“…Taken together, these results elucidated the function of SIRT3 in hepatocellular carcinoma development and suggested that SIRT3 might function as tumor suppressor in hepatocellular carcinoma by targeting PI3K/Akt pathway.…”
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Coactivator-associated arginine methyltransferase 1 promotes cell growth and is targeted by microRNA-195-5p in human colorectal cancer
Published 2017-03-01“…These data confirm that microRNA-195-5p might function as an anti-tumor microRNA in colorectal cancer exerting critical control over coactivator-associated arginine methyltransferase 1 expression. …”
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Genetic polymorphism of interferon regulatory factor 5 (IRF5) correlates with allograft acute rejection of liver transplantation.
Published 2014-01-01“…<h4>Conclusions</h4>IRF5, which transcriptionally activates inflammatory cytokines, is genetically associated with acute rejection and might function as a risk factor for acute rejection of liver transplantations.…”
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Gut Microbiota, Circulating Metabolites and Risk of Endometriosis: A Two-Step Mendelian Randomization Study
Published 2024-12-01“…Two-step MR analysis indicated that specific microbial taxa, notably genus Enterorhabdus and order Selenomonadales, might function as mediators linking circulating metabolites to the risk of EMs. …”
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αSnap plays a pivotal role in the maintenance of Drosophila ISCs survival and tissue homeostasis
Published 2025-05-01“…Furthermore, the depletion of αSnap in ISCs promotes the expression of Calr, Prtp, LRP1 and Mcr, which might function downstream of αSnap in regulating the survival of ISCs. …”
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The Essential Oil Component Terpinyl Acetate Alters Honey Bee Energy Levels and Foraging Behavior
Published 2025-05-01“…Using a cell culture model system, we found that terpinyl acetate is a potent and specific inhibitor of mitochondrial ATP production, suggesting it might function as a plant toxin. Remarkably, however, terpinyl acetate was not cytotoxic because cells switched to glycolysis to maintain ATP levels. …”
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Nonmetastatic cell 1 gene polymorphisms are associated with the clinical progression and prognoses of patients with colorectal cancer
Published 2025-05-01“…Moreover, survival analysis revealed that patients with the homozygous mutant TT genotype of rs2302254 had significantly shorter disease-free survival (DFS) and overall survival (OS) times than patients with the homozygous wild-type CC genotype.ConclusionThe rs2302254 polymorphism might function as a potential molecular marker for predicting the progression and prognosis of CRC.…”
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SIRT2-dependent DKK1 deacetylation aggravates polycystic ovary syndrome by targeting the TGF-β1/Smad3 signaling pathway
Published 2024-12-01“…The above results indicated that DKK1 might function as a latent target for P COS treatment.…”
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Movement-related theta rhythm in humans: coordinating self-directed hippocampal learning.
Published 2012-01-01“…Recent evidence suggests that the hippocampus might function as a network hub for volitional learning. …”
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The Two Sides of Indoleamine 2,3-Dioxygenase 2 (IDO2)
Published 2024-11-01“…New insights suggest that IDO2 might function more as a signaling molecule, particularly in cancer contexts, and further studies could reveal its potential as a target for cancer therapy.…”
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Bioinformatics analysis of miR-2861 and miR-5011-5p that function as potential tumor suppressors in colorectal carcinogenesis
Published 2025-01-01“…Conclusion These findings imply that miR-2861 and miR-5011-5p might function as tumor suppressors in the development of CRC.…”
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Gene markers of fracture healing in early stage and the regulatory mechanism during the process using microarray analysis
Published 2016-12-01“…Eftud2, Snrpd2, Bub1b and Plk1 might function through the involvement of cell-cycle-related BP, while Ubc might influence the protein degradation during bone development. …”
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Long non-coding RNA MSTO2P promotes the proliferation and colony formation in gastric cancer by indirectly regulating miR-335 expression
Published 2017-05-01“…Therefore, long non-coding RNAs might function as key regulatory hubs in gastric cancer progression.…”
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Roles of microRNA let-7b in papillary thyroid carcinoma by regulating HMGA2
Published 2017-10-01“…Moreover, high-mobility group A2 reintroduction reversed the anti-proliferation, anti-migration, and anti-invasion roles of let-7b. Let-7b might function as a tumor suppressor in papillary thyroid carcinoma by suppressing the expression of high-mobility group A2, and therefore might provide a promising therapeutic target for patients with papillary thyroid carcinoma.…”
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Spoken words affect visual object recognition via the modulation of alpha and beta oscillations
Published 2025-04-01“…These results suggest that alpha and beta rhythms may play distinct functional roles to support language-mediated visual object recognition: alpha might function to amplify sensory representations in posterior regions, while beta may (re)activate the network states elicited by the auditory cue.…”
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TaZFP 23, a new Cys2/His2-type zinc-finger protein, is a regulator of wheat (Triticum aestivum L.) growth and abiotic stresses
Published 2025-02-01“…Promoter cis-acting element analysis suggested that TaZFP23 might function in abiotic stress responses and plant hormone signal transduction. …”
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