Advances, challenges and future applications of liver organoids in experimental regenerative medicine by Da Gong, Jiaye Mo, Jiaye Mo, Mei Zhai, Fulin Zhou, Guocai Wang, Shaohua Ma, Xiaoyong Dai, Xiaoyong Dai, Xuesong Deng

Subjects: Get full text

The Impact of Targeted Therapies on Red Blood Cell Aggregation in Patients with Chronic Lymphocytic Leukemia Evaluated Using Software Image Flow Analysis by Anika Alexandrova-Watanabe, Emilia Abadjieva, Lidia Gartcheva, Ariana Langari, Miroslava Ivanova, Margarita Guenova, Tihomir Tiankov, Velichka Strijkova, Sashka Krumova, Svetla Todinova

Subjects: Get full text

Recent advancements in Point-of-Care Detection of Contaminants and Biomarkers in Human Breast Milk: A comprehensive review by Shruti Janakiraman, Rinky Sha, Naresh Kumar Mani

Get full text

Monitoring the impact of confinement on hyphal penetration and fungal behavior. by Yi-Syuan Guo, Julian A Liber, Jennifer L Morrell-Falvey, Gregory Bonito, Scott T Retterer

“…Our results provide a repeatable and easy-to-use approach for culturing fungi within a microfluidics platform and for visualizing the impact of confinement on hyphal growth and other fungal behaviors pertinent to their remodeling of the underground environment.…”
Get full text

A self-powered soft triboelectric-electrohydrodynamic pump by Fangming Li, Shuowen Sun, Xingfu Wan, Minzheng Sun, Steven L. Zhang, Minyi Xu

“…Abstract Soft pumps have the potential to transform industries including soft robotics, wearable devices, microfluidics and biomedical devices, but their efficiency and power supply limitations hinder prolonged operation. …”
Get full text

Recent Advances in Peptide-Loaded PLGA Nanocarriers for Drug Delivery and Regenerative Medicine by Hossein Omidian, Renae L. Wilson, Ana M. Castejon

“…Innovations in polymer chemistry, surface functionalization, and advanced manufacturing techniques, such as microfluidics and electrospraying, have further enhanced the efficacy and scalability of these systems. …”
Get full text

Unveiling the complex morphologies of sessile droplets on heterogeneous surfaces by Yanchen Wu, Hongmin Zhang, Fei Wang, Britta Nestler

“…This work provides a potential method to achieve highly complex morphologies of droplets via low-cost beforehand design of the surfaces, thereby opening up potential applications in 3D printing, printed electronics, and microfluidics.…”
Get full text

Metasurface-Enabled Microphotonic Biosensors via BIC Modes by Francesco Dell’Olio

“…Finally, the review discusses future challenges and opportunities, such as integration with microfluidics for point-of-care testing and multiplexed sensing, underscoring the potential of BIC-based platforms to revolutionize the field of biosensing.…”
Get full text

Portable solutions for plant pathogen diagnostics: development, usage, and future potential by Anurag Yadav, Kusum Yadav

“…This review explores portable diagnostic technologies’ development, deployment, and future potential, including handheld analyzers, smartphone-integrated systems, microfluidics, and lab-on-a-chip platforms. We examine the core technologies underlying these devices, such as biosensors, nucleic acid amplification techniques, and immunoassays, highlighting their applicability to detect bacterial, viral, and fungal pathogens in diverse agricultural settings. …”
Get full text

Quantifying glucose uptake at the single cell level with confocal microscopy reveals significant variability within and across individuals by Joel D. Paprocki, Patrick J. Macdonald, Yongjin Xu, Alan Cheng, Timothy C. Dunn, Sergey Y. Tetin

“…Here, we devised a fluorescence-based method to quantitatively observe GLUT1-mediated intracellular glucose analog tracer uptake in individual RBCs utilizing microfluidics and confocal microscopy. For the first time, we demonstrate that intracellular/extracellular tracer percentages can be measured at the single cell level using the fluorescently labeled glucose analog, 2-NBDG. …”
Get full text

The Pre-Polarization and Concentration of Cells near Micro-Electrodes Using AC Electric Fields Enhances the Electrical Cell Lysis in a Sessile Drop by Kishor Kaphle, Dharmakeerthi Nawarathna

“…Additionally, the utility of syringe pumps for flow cells in and out of the microfluidics channel causes cell loss and low throughput cell lysis. …”
Get full text

Droplet-based high-throughput 3D genome structure mapping of single cells with simultaneous transcriptomics by Honggui Wu, Maoxu Wang, Yinghui Zheng, X. Sunney Xie

“…Here we introduce a high-throughput single-cell Hi-C (dscHi-C) approach and its transcriptome co-assay (dscHi-C-multiome) using droplet microfluidics. Using dscHi-C, we investigate chromatin structural changes during mouse brain aging by profiling 32,777 single cells across three developmental stages (3 months, 12 months, and 23 months), yielding a median of 78,220 unique contacts. …”
Get full text

Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation by Chunxiang Lu, Aoxiang Jin, Chuang Gao, Hao Qiao, Huazhen Liu, Yi Zhang, Wenbin Sun, Shih-Mo Yang, Yuanyuan Liu

“…Spheroids, as three-dimensional (3D) cell aggregates, can be prepared using various methods, including hanging drops, microwells, microfluidics, magnetic manipulation, and bioreactors. …”
Get full text

Advancements in nanosensors for cancer detection by Dinesh Bhatia, Tania Acharjee, Monika Bhatia

“…The accuracy and usability of detection are further improved by advancements in wearable technologies, microfluidics, and electrochemical and graphene-based sensors. …”
Get full text

Microhabitat accessibility determines peptide substrate degradation by soil microbial community by Carlos Arellano-Caicedo, Pelle Ohlsson, Saleh Moradi, Edith C. Hammer

“…In the present study, by using microfluidics, we tested the effect of labyrinth-like structures of decreasing accessibility on the decomposing activity of soil microbial communities from a soil inoculum. …”
Get full text

Biocompatible Heterogeneous Packaging and Laser-Assisted Fluid Interface Control for In Situ Sensor in Organ-on-a-Chip by Yu-Hsuan Lin, Shing-Fung Lau, Yen-Pei Lu, Kuo-Cheng Huang, Chien-Fang Ding, Yu-Hsiang Tang, Hsin-Yi Tsai

“…By integrating precise biological and fluid condition sensing with microfluidics and electronic components, long-term dynamic closed-loop culture systems can be achieved. …”
Get full text

Thermocapillary convection in superimposed fluids confined within superhydrophobic surfaces of a microchannel by Radi A. Alsulami, Kanchathan Wasuwatthanakul, Kannan Premnath, Mutabe Aljaghtham, Saad Adam

“…Microfluidic applications based on thermocapillary effects have recently gained considerable attention due to the transport phenomena driven by the dominant surface tension forces. …”
Get full text

A comprehensive review of AI-based collagen valorization: Recent trends, innovations in extraction, and applications by Arthi Srinivasan, Arun Gupta, Vigneswaran Narayanamurthy

Get full text

High throughput single cell metagenomic sequencing with semi-permeable capsules: unraveling microbial diversity at the single-cell level in sewage and fecal microbiomes by Meilee Ling, Judit Szarvas, Vaida Kurmauskaitė, Vaidotas Kiseliovas, Rapolas Žilionis, Rapolas Žilionis, Baptiste Avot, Baptiste Avot, Patrick Munk, Frank M. Aarestrup

“…Here, we validated the use of microfluidics and semi-permeable capsules (SPCs) technology (Atrandi) to isolate individual bacterial cells from sewage and pig fecal samples. …”
Get full text

Graphene nanomaterial-based electrochemical biosensors for salivary biomarker detection: A translational approach to oral cancer diagnostics by D. Mahalakshmi, J. Nandhini, G. Meenaloshini, E. Karthikeyan, KK Karthik, J. Sujaritha, Vandhana, V, C. Ragavendran

“…Finally, we present a futuristic outlook on the integration of graphene-based biosensors with artificial intelligence, microfluidics, and telemedicine platforms to enable personalized diagnostics and treatment monitoring. …”
Get full text