Serum HDL and their subfractions are impaired in multisystem inflammatory syndrome in children (MIS-C) by Antonietta Giannattasio, Alice Castaldo, Michela Grieco, Monica Gelzo, Gustavo Cernera, Giuseppe Castaldo, Vincenzo Tipo

“…We analyzed serum cholesterol, HDL and HDL-SUB (by capillary electrophoresis) in relation to serum values of biomarkers of inflammation and endothelial damage (by microfluidic immunoassays) in 48 patients with MIS-C at hospital admission and in 48 age- and sex-matched healthy controls. …”
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Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration by Francisca L. Gomes, Francisco Conceição, Liliana Moreira Teixeira, Jeroen Leijten, Pascal Jonkheijm

“…<b>Results:</b> We achieve a PCL MP size distribution of 99.8% below this size limit, and prove that these particles can flow without obstruction through a microfluidic model emulating a thin human blood capillary (4.1 µm × 3.0 µm width × heigh). …”
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Data-driven prediction of critical diameter for deterministic lateral displacement devices: an integrated DPD-ML approach by Shuai Liu, Peng Zhang, Anbin Wang, Keke Tang, Shuo Chen, Chensen Lin

“…However, current DLD design lacks clear guidance and heavily depends on expert experience, requiring extensive repetitive microfluidic experiments and numerical simulations. This leads to significant economic and time costs, while the complexity of instruments and algorithms further raises the barrier for DLD design and optimization. …”
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A human skin-on-a-chip platform for microneedling-driven skin cancer treatment by Natan R. Barros, Raehui Kang, Jinjoo Kim, Menekse Ermis, Han-Jun Kim, Mehmet R. Dokmeci, Junmin Lee

“…Here, we developed a human skin/skin cancer-on-a-chip platform within a microfluidic device using bioprinting/bioengineering techniques. …”
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Sustained release of miR-21 carried by mesenchymal stem cell-derived exosomes from GelMA microspheres inhibits ovarian granulosa cell apoptosis in premature ovarian insufficiency by Xiaofei Zhang, Linzi Ma, Xiaotong Liu, Xingyu Zhou, Ao Wang, Yunhui Lai, Jun Zhang, Ying Li, Shiling Chen

“…Moreover, we successfully developed GelMA hydrogel microspheres for encapsulating Agomir21-Exo through microfluidic technology, named GelMA-Ag21Exo, which had good injectability and significantly enhanced the stability and long-term retention of Agomir21-Exo in mice through sustained release. …”
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Optimizing droplet coalescence dynamics in microchannels: A comprehensive study using response surface methodology and machine learning algorithms by Seyed Morteza Javadpour, Erfan Kadivar, Zienab Heidary Zarneh, Ebrahim Kadivar, Mohammad Gheibi

“…This comprehensive approach provides valuable insights into droplet coalescence phenomena and offers a robust framework for optimizing microfluidic systems. The most influential parameters on DD are the values of Ad and D, while viscosity has the lowest influence on DD. …”
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Skeletal muscle ribosome analysis: A comparison of common assay methods and utilization of a novel RiboAb antibody cocktail by Joshua S. Godwin, J. Max Michel, C. Brooks Mobley, Gustavo A. Nader, Michael D. Roberts

“…Thus, total RNA concentrations ([RNA]) provided through UV–Vis spectroscopy (UV), fluorometry‐only (Fluor), and fluorometry‐based microfluidic chip electrophoresis (MFGE) were examined in C2C12 myotubes and mouse skeletal muscle to determine if values aligned with [18S + 28S rRNA] (i.e., criterion ribosome metric). …”
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Droplets Cas13a‐RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer by Jingsong Xu, Li Cao, Shuang Yang, Ying Jian, Yu Liu, Zhen Shen, Qian Liu, Xiang Chen, Min Li, Shun Li, Xiaolei Zuo, Min Li, Hua Wang

“…A new technology named µDCR, which accurately detects circWDR37, has been developed by combining microfluidic droplets with CRISPR/Cas13a and recombinase polymerase amplification (RPA). …”
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Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1-4: A scoping review to inf... by Paul Arkell, Dumrong Mairiang, Adisak Songjaeng, Kenny Malpartida-Cardenas, Kerri Hill-Cawthorne, Panisadee Avirutnan, Pantelis Georgiou, Alison Holmes, Jesus Rodriguez-Manzano

“…Fourteen studies using previously described assays were identified, including those where reagents were lyophilised or 'printed' into microfluidic channels and where several novel detection methods were used. …”
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Curcumin nanocrystals ameliorate ferroptosis of diabetic nephropathy through glutathione peroxidase 4 by Mengjiao Xue, Mengjiao Xue, Yiwei Tian, Hua Zhang, Hua Zhang, Shijie Dai, Yangsheng Wu, Juan Jin, Juan Jin, Jian Chen

“…The purpose is to determine whether Cur NCs can become a promising treatment option for diabetes nephropathy by reducing ferroptosis.MethodsCur-NCs were prepared using microfluidic technology and studied using dynamic light scattering and transmission electron microscopy. …”
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Myeloid dendritic cells and periodontal disease association: integrated study of single-cell sequencing and Mendelian randomization analysis by ChengJi Shi, XinYi Ou, XiaoXu Lei, LiJuan Huang, ShuHao Xu, Wei Li, Xi Zhao

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Leveraging the fundamentals of heat transfer and fluid mechanics in microscale geometries for automated next-generation sequencing library preparation by Olivia Ott, Sabrina Tolppi, Jennifer Figueroa-Cruz, Khaliun Myagmar, Khulan Unurbuyan, Anubhav Tripathi

“…We present an innovative automated NGS library preparation system with a simplified mechanical design that exploits both macro- and microfluidic properties for optimizing heat transfer, reaction kinetics, mass transfer, fluid mechanics, adsorption–desorption rates, and molecular thermodynamics. …”
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Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination by Henry M. Vu, Thomas E. Moran, Zhong Liang, Yun-Juan Bao, Paulina G. Carles, Jessica C. Keane, Madelyn G. Cerney, Caitlyn N. Dahnke, Ana L. Flores-Mireles, Victoria A. Ploplis, Francis J. Castellino, Shaun W. Lee

“…To gain a more fully realized model of how GAS trapped in fibrin clots can disseminate in the blood system, we utilized a novel 3D endothelial microfluidic device to demonstrate that GAS is fully capable of fibrinolysis in an endothelial environment, revealing a major underappreciated route by which GAS may cause more invasive outcomes. …”
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β-synuclein in cerebrospinal fluid as a potential biomarker for distinguishing human prion diseases from Alzheimer’s and Parkinson’s disease by Bing Xu, Kang Xiao, Xiaoxi Jia, Rundong Cao, Donglin Liang, Ruhan A, Weiwei Zhang, Chunjie Li, Liping Gao, Cao Chen, Qi Shi, Xiaoping Dong

“…The CSF β-syn levels were measured by a commercial microfluidic ELISA. The Mann–Whitney U test and Kruskal–Wallis H test were employed to analyze two or more sets of continuous variables. …”
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Semaphorin-4D signaling in recruiting dental stem cells for vascular stabilization by Lili Zhang, Dineshi Sewvandi Thalakiriyawa, Jiawei Liu, Shengyan Yang, Yan Wang, Waruna Lakmal Dissanayaka

“…Additionally, a three-dimensional vasculature-on-a-chip microfluidic device was used to investigate the role of M2c macrophage-derived Sema4D in the stabilization of vascular structures. …”
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