Optofluidic paper-based analytical device for discriminative detection of organic substances via digital color coding by Jinsol Choi, Chi Yeung Oh, Gong Qian, Tae Soup Shim, Heon-Ho Jeong

“…We fabricate an optofluidic PAD by integrating two coding units into a three-dimensional (3D) microfluidic paper within a 3D-printed cartridge. The optofluidic PADs clearly distinguish 11 organic chemicals with digital readout of pattern recognition from colorimetric signals. …”
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Metal ion-crosslinking multifunctional hydrogel microspheres with inflammatory immune regulation for cartilage regeneration by Zhuoming Xu, Zhuoming Xu, Jun Ma, Hanyin Hu, Hanyin Hu, Jintao Liu, Jintao Liu, Haiyang Yang, Haiyang Yang, Jiayi Chen, Hongwei Xu, Xinyu Wang, Huanhuan Luo, Gang Chen

“…Due to the complex pathogenesis of OA, multifaceted therapies that modulate inflammatory and immune microenvironmental disturbances while promoting cartilage regeneration are key to control the progression of OA.MethodsHerein, a multifunctional nanoparticle (DIC/Mg-PDA NPs) was constructed successfully by the metal chelation effect between Mg2+ and catecholamine bond from dopamine, followed by the amidation with diclofenac (DIC), which was then prepared into an injectable hydrogel microsphere (DIC/Mg-PDA@HM) with immune-regulating and cartilage-repairing abilities through microfluidic technology for the treatment of osteoarthritis.Results and discussionThe sustained release of Mg2+ from the composite hydrogel microspheres achieved inflammatory immune regulation by converting macrophages from M1 to M2 and promoted cartilage regeneration through the differentiation of BMSCs. …”
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Scalable fabrication of an array-type fixed-target device for automated room temperature X-ray protein crystallography by Sarthak Saha, Yaozu Chen, Silvia Russi, Darya Marchany-Rivera, Aina Cohen, Sarah L. Perry

“…Inspired by grid-style devices that have been reported in the literature, we have developed an X-ray compatible microfluidic device that can be used to trap protein crystals in an array configuration, while also providing excellent optical transparency, a low X-ray background, and compatibility with the robotic sample handling and environmental controls used at synchrotron macromolecular crystallography beamlines. …”
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Gold Nanorod-Coated Hydrogel Brush Valves in Macroporous Silicon Membranes for NIR-Driven Localized Chemical Modulation by Nafis Mustakim, Youngsik Song, Sang-Woo Seo

“…A two-dimensional array of microfluidic ports with remote-controlled valve actuation is of great interest for applications involving localized chemical stimulation. …”
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A Simple Way to Achieve Self-Cleaning Surfaces with Unique Antifouling Property by Caizhen Yao, Shizhen Xu, Xiaodong Jiang, Jiaxuan Chen, Xiaodong Yuan

“…Self-cleaning surfaces may have wide applications such as microfluidic devices, lab-on-a-chip, sensors, microreactors, air purification, and antimicrobial fields. …”
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Migration and proliferation drive the emergence of patterns in co-cultures of differentiating vascular progenitor cells by Jose E. Zamora Alvarado, Kara E. McCloskey, Ajay Gopinathan

“…These findings computationally supported that 2D patterning is mechanistically similar to current microfluidic platforms that take advantage of the migration-directed self-assembly of mature endothelial and mural cells to generate perfusable 3D vasculature in permissible hydrogel environments and suggest that stem or progenitor cells may not be fully necessary components in many tissue formations like those formed by vasculogenesis.…”
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Advancing nuclear transfer cloning in zebrafish (Danio rerio) into a translational pathway using interdisciplinary tools. by Sarah Bodenstein, William Poulos, Fermin Jimenez, Michael Stout, Yue Liu, Zoltan M Varga, Jose Cibelli, Terrence R Tiersch

“…Chemical dechorionation and microfluidic devices to aid micromanipulation were identified as ways to eliminate these constraints. …”
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Nonlinear Damping as the Fourth Dimension in Optical Fiber Anemometry by Jeremiah C. Williams, Hengky Chandrahalim

“…To stabilize the rotation of the rotor and facilitate consistent frequency‐domain analysis, a polydimethylsiloxane hydrocarbon stabilizing agent is infused into the gap between the rotor and stator of the sensing element via dual‐function microfluidic channels. This enhancement allows for the measurement of gaseous nitrogen flow rates from 10 to 20 liters per minute (LPM), with a consistent periodic response. …”
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Recent advances in oblique plane microscopy by Kim Jeongmin

“…OPM has strong potential in a variety of research fields, including cellular and developmental biology, clinical diagnostics in histology and ophthalmology, flow cytometry, microfluidic devices, and soft materials.…”
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Numerical investigation of heat and mass transfer for unsteady multiphase flow in a vented cavity filled with hybrid nanofluid by Muhammad Ashhad Shahid, Mojtaba Dayer, Muhammad Adil Sadiq, Haris Ali, Ishak Hashim

“…Effective heat and mass transfer is crucial for enhancing efficiency and performance, particularly under varying flow conditions in devices such as heat exchangers, microfluidic systems, and chemical reactors. The current study investigates the effect of novel combination of unsteady condition and multiphase flow effect on hybrid nanofluid (HNF) convective heat and mass transfer (CHMT) within a vented cavity. …”
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Diffusion-programmed catalysis in nanoporous material by Suvendu Panda, Tanmoy Maity, Susmita Sarkar, Arun Kumar Manna, Jagannath Mondal, Ritesh Haldar

“…Through the deployment of a thin film composed of a porous metal-organic framework catalyst, we illustrate how programming reactant diffusion within a cross-flow microfluidic catalytic reactor can concurrently amplify turnover frequency (exceeding 1000-fold) and enhance geometric selectivity ( ~ 2-fold) relative to conventional nano/microcrystals of catalyst in one-pot reactor. …”
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Ultrafast laser welding of transparent materials: from principles to applications by Xianshi Jia, Jinlin Luo, Kai Li, Cong Wang, Zhou Li, Mengmeng Wang, Zhengyi Jiang, Vadim P Veiko, Ji’an Duan

“…The local thermal melting and connection properties of the ultrafast laser welding technology offer a novel method for welding of diverse transparent materials, thus having wide range of potential applications in aerospace, opto-mechanical systems, sensors, microfluidic, optics, etc. In this comprehensive review, tuning the transient electron activation processes, high-rate laser energy deposition, and dynamic evolution of plasma morphology by the temporal/spatial shaping methods have been demonstrated to facilitate the transition from conventional homogeneous transparent material welding to the more intricate realm of transparent/metal heterogeneous material welding. …”
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Nanotechnology-driven electrochemical neurotransmitter sensing as a fundamental approach towards improving diagnostics and therapeutics: A review by Mehr Un Nisa, Asim Yaqub, Muhammad Hashim Khan, Fatima Yaseen, Shahaab Jilani, Huma Ajab, Noor S. Shah, Abdulaziz Al-Anazi

“…This review additionally looks at the progress accomplished in biosensors for neurotransmitter evaluations in microfluidic lab-on-a-chip systems, smart wearable devices and other advanced technologies for the goal of real-time, portable diagnosis in neuroscience and clinics. …”
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Design of hollow tapered PMMA polymeric microneedles for enhanced structural stability and drug delivery efficiency by Aswani Kumar Gera, Rajesh Kumar Burra

“…The finite element analysis tool is used to enhance the microneedle design by varying the outer base radius and tip radii to mitigate the von Mises stress that is exhibited during axial load and bending load conditions. In addition, microfluidic analysis is to assess the fluid flow behavior through the hollow microneedles, measuring the flow rates of fluids (water, glucose, and insulin).Simulated results reveal that an axial stress of 3.26 × 106 N/m2 and bending stress of 2.31 × 107 N/m2 were reported, which are below the yield strength of the material and satisfy the criteria for successful microneedle penetration. …”
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Advances in liver organoids: replicating hepatic complexity for toxicity assessment and disease modeling by Weidong Shao, Hui Xu, Kanghua Zeng, Mingzhou Ye, Renjun Pei, Kai Wang

“…The integration of liver organoids with microfluidic devices enables the simulation of the liver microenvironment and facilitates high-throughput drug screening. …”
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Elastic deformation impact on trihybrid nanofluid flow through different geometries with the combine effects of electrophoresis and thermophoresis by Munawar Abbas, A. Al-Zubaidi, Abdullah A. Faqihi, Ilyas Khan, A.F. Aljohani, Abdoalrahman S.A. Ome, Ahmed M. Gala

“…Improvements in heat transmission in microfluidic and nanofluidic devices are critical for chemical reactions, electronics cooling, and biological applications. …”
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Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay by Danielle W. Ali, Maggie L. Bartlett, Christopher D. Heger, Francisco Ramirez, Linwood Johnson, Kevin L. Schully, Eric D. Laing, Wei Wang, Carol D. Weiss, Emilie Goguet, Christopher C. Broder, Stephanie A. Richard, Nusrat J. Epsi, Brian Agan, David Tribble, Mark P. Simons, Timothy H. Burgess, Edward Mitre, Simon Pollett, Darci R. Smith

“…Here we tested a prototype automated microfluidic cartridge-based sVNT platform using SARS-CoV-2 wild-type (WT) and B.1.617.2 (Delta) variant RBDs. …”
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Isolation and Characterization of Nanofibrillar Cellulose from Agave tequilana Weber Bagasse by Hasbleidy Palacios Hinestroza, Javier A. Hernández Diaz, Marianelly Esquivel Alfaro, Guillermo Toriz, Orlando J. Rojas, Belkis C. Sulbarán-Rangel

“…To obtain the nanofibrils, the cellulose was passed through 6 cycles of a microfluidizer. The material was classified by FTIR, confirming the presence of the functional groups (O-H, C-H, C-C, and C-O-C), characteristics of cellulose, and the elimination of hemicellulose and lignin present in agave bagasse without treatment. …”
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Rapid isolation and recovery of Salmonella using hollow glass microspheres coated with multilayered nanofilms by Rutwik Joshi, Hesaneh Ahmadi, Md Nayeem Hasan Kashem, Fariha Afnan, Siva Parameswaran, Chau-Chyun Chen, Gizem Levent, Wei Li

“…Despite the progress of innovative microfluidic or immunomagnetic isolation techniques, sophisticated lab equipment and microfabrication are often needed. …”
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Protective Effect of Uric Acid on ox-LDL-Induced HUVECs Injury via Keap1-Nrf2-ARE Pathway by Yajuan Lin, Yunpeng Xie, Zhujing Hao, Hailian Bi, Yang Liu, Xiaolei Yang, Yunlong Xia

“…Coimmunoprecipitation was used to determine the level of Nrf2 ubiquitination. A microfluidic device was used to mimic the vascular environment in the body, and the level of mRNA levels of inflammatory factors was determined by RT-PCR. …”
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