Flexible Surface Acoustic Wave Device with AlN Film on Polymer Substrate by Jian Zhou, Shurong Dong, Hao Jin, Bing Feng, Demiao Wang

“…Surface acoustic wave device with c-axis-oriented aluminum nitride (AlN) piezoelectric thin films on polymer substrates can be potentially used for development of flexible sensors, flexible microfluidic applications, microsystems, and lab-on-chip systems. …”
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Multi-Template Molecularly Imprinted Polymeric Electrochemical Biosensors by Meltem Agar, Maisem Laabei, Hannah S. Leese, Pedro Estrela

“…Furthermore, this work highlights the use of these sensors for point-of-care applications, their commercialization and their integration with microfluidic systems.…”
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Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly by Sushruta Surappa, Suraj Pavagada, Fernando Soto, Demir Akin, Charles Wei, F. Levent Degertekin, Utkan Demirci

“…We further demonstrate the capabilities of the reconfigurable metasurface in trapping and enriching beads and biological cells flowing in microfluidic channels, showcasing its potential in high-throughput bioanalytical applications. …”
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Fully automated in vivo screening system for multi-organ imaging and pharmaceutical evaluation by Junhan Duan, Guanming Lin, Kangjian Jiao, Xiaohui Hong, Xudong Lin

“…Here, we develop and validate a fully automated in vivo screening system (AISS) that integrates microfluidic technology and computer-vision-based control methods to enable rapid evaluation of biological responses of non-anesthetized zebrafish to molecular gradients. …”
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Innovative Lipid Nanoparticles Co-Delivering Hydroxychloroquine and siRNA for Enhanced Rheumatoid Arthritis Therapy by Yanru Feng, Xintong Pan, Ziqian Li, Yue Li, Ya’nan Sun, Shaokun Yang, Chaoxing He, Yunjie Dang, Lu Huang, Bai Xiang

“…<b>Methods:</b> In this study, we introduce a novel lipid nanoparticle formulation co-delivering hydroxychloroquine (HCQ) and siRNA targeting TNF-α (si<i>TNF-α</i>) using microfluidic technology, marking the first use of such a combination for RA therapy. …”
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Design and Bulk Sensitivity Analysis of a Silicon Nitride Photonic Biosensor for Cancer Cell Detection by Prasanna Kumaar S., Sivabramanian A.

“…Integrating polydimethylsiloxane (PDMS) microfluidic channel in sensor architecture decreases the sensitivity due to leakage of molecules at edges. …”
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Research progress on preparation methods of polyvinylidene by Lijuan YAN, Yajing XUN, Kunru MA, Yunlan SUN

“…Based on the extensive research on PVDF modified boron and aluminum energetic materials at home and abroad in recent years, ten mainstream techniques were summarized and refined, including solvent volatilization method, electrospinning technology, electrostatic spray technology, electrospray deposition method, microemulsion method, 3D printing technology, vacuum freeze-drying method, non-solvent induced phase separation method, liquid phase method and droplet microfluidic technology. Their preparation principles, application scenarios, advantages and disadvantages were described, the challenges of PVDF modified energetic materials were further pointed out, and the key directions for future research were proposed:1) safety improvements; 2) green technologies; 3) nanomaterial optimisation; 4) multi-scale design; 5) innovative coating methods; and 6) insight into reaction mechanisms.…”
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Revolutionizing precision medicine in oral squamous cell carcinoma: Harnessing 3D in vitro models for translation by Nitesh Buldak, Vishnu Priya Veeraraghavan, Ullas Mony

“…Advanced models such as tumor spheroids, patient organoids and microfluidic devices offer unique possibilities to reconstitute intricate cellular interactions, ECM dynamics as well as physiological gradients found in the OSCC TME. …”
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Development of a low-cost flexible potentiometric detector and its integrated system for electrochemical sensing of electrolytes in human sweat by Chaojiang Li, Yuxuan Liu, Guodong Liu, Qifeng Tan, Xiaolong Dou, Yuting Xie, Xianchao Zhang

“…Electrolyte electrochemical detection has been achieved by integrating wearable microfluidic electrochemical sensing devices and establishing wireless communication with smartphone applications. …”
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Self-driving lab for the photochemical synthesis of plasmonic nanoparticles with targeted structural and optical properties by Tianyi Wu, Sina Kheiri, Riley J. Hickman, Huachen Tao, Tony C. Wu, Zhi-Bo Yang, Xin Ge, Wei Zhang, Milad Abolhasani, Kun Liu, Alan Aspuru-Guzik, Eugenia Kumacheva

“…Here, we introduce the Autonomous Fluidic Identification and Optimization Nanochemistry (AFION) self-driving lab that integrates a microfluidic reactor, in-flow spectroscopic nanoparticle characterization, and machine learning for the exploration and optimization of the multidimensional chemical space for the photochemical synthesis of plasmonic nanoparticles. …”
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Progress in Continuous Flow Synthesis of Hydrogen-Bonded Organic Framework Material Synthons by Xingjun Yao, Sanmiao Wen, Ningning Ji, Qiulin Deng, Zhiliang Li, Hongbing Wang, Qianqian Shang

“…Continuous flow reactors facilitate fast chemical reactions and precise microfluidic control, offering superior reaction speed, product yield, and selectivity compared to batch processes. …”
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Numerical study of enhanced nanofluid heat transfer in an open cavity with heated obstacles using LBM by Makaoui Abdelilah, Lahmer El Bachir, Benhamou Jaouad, Moussaoui Mohammed Amine, Mezrhab Ahmed

“…This study highlights the pivotal role of nanoparticle concentration and obstacle orientation in optimising the thermal management of microfluidic devices and electronic cooling systems.…”
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Black Phosphorus Tagged Responsive Strontium Hydrogel Particles for Bone Defect Repair by Zhengwei Liu, Hui Zhang, Jingjing Gan, Yuanjin Zhao, Yongxiang Wang

“…Herein, a novel black phosphorus (BP) tagged responsive strontium (Sr) hydrogel particles are presented for bone defect repair. By applying microfluidic technology, Sr and carboxymethyl chitosan, and BP are integrated into poly(N‐isopropyl acrylamide) (pNIPAM) hydrogel matrix to generate such microparticles called pNBCSMs. …”
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Optical widefield nuclear magnetic resonance microscopy by Karl D. Briegel, Nick R. von Grafenstein, Julia C. Draeger, Peter Blümler, Robin D. Allert, Dominik B. Bucher

“…We demonstrate that our optical widefield NMR microscopy can image NMR signals in microfluidic structures with a ~10 μm resolution across a ~235 × 150 μm2 area. …”
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Finite-Element Simulation of Electroosmotic Mixing: A Study of the Simultaneous Effects of Working Parameters for Optimization by Reza Kalantar Feeoj, Sayed Masoud Alavi Eshkaftaki, Iman Kazemi Asfeh, Mehdi Jahangiri

“…Micromixers are crucial parts of microfluidic systems when it comes to efficiency and precision, as mixing is the central process in most relevant applications, including medical diagnosis, chemical production, and drug discovery. …”
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Neuromorphic-enabled video-activated cell sorting by Weihua He, Junwen Zhu, Yongxiang Feng, Fei Liang, Kaichao You, Huichao Chai, Zhipeng Sui, Haiqing Hao, Guoqi Li, Jingjing Zhao, Lei Deng, Rong Zhao, Wenhui Wang

“…NEVACS adopts event camera, CPU, spiking neural networks deployed on a neuromorphic chip, and achieves sorting throughput of 1000 cells/s with relatively economic hybrid hardware solution (~$10 K for control) and simple-to-make-and-use microfluidic infrastructures. Particularly, the application of NEVACS in classifying regular red blood cells and blood-disease-relevant spherocytes highlights the accuracy of using video over a single frame (i.e., average error of 0.99% vs 19.93%), indicating NEVACS’ potential in cell morphology screening and disease diagnosis.…”
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Strategies Affording Prevascularized Cell-Based Constructs for Myocardial Tissue Engineering by Claudio Muscari, Emanuele Giordano, Francesca Bonafè, Marco Govoni, Carlo Guarnieri

“…Technologies exerting spatial control of vascular cells, such as topographical surface roughening and ordered patterning, represent other ways to drive scaffold vascularization. Finally, microfluidic devices and bioreactors exerting mechanical stress have also been employed for high-throughput scaling-up production in order to accelerate muscle differentiation and speeding the endothelialization process. …”
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Innovations in intestinal organoid technology featuring an open apical surface by Ye Chen, Yi Wang

“…To address these challenges, recent advancements have introduced Transwell-based monolayer cultures and microfluidic device-based technologies including “organ-on-a-chip” and scaffold-guided 'mini-gut' system. …”
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Exploring the implications of ternary Jeffrey nanofluid on pulsating flow and heat transfer through unsymmetrical corrugated micro conduit by Mohamed S. Abdel-wahed, Khaled S. Mekheimer, Ahmed Y. Sayed, Shaaban I. Ahmed

“…Using the perturbation method and Mathematica software, we derived semi-analytical solutions for the governing partial differential equations in their complex form. nanoparticle-enhanced blood exhibits improved thermal performance compared to pure fluid, with the type and concentration of nanoparticles (Fe3O4, Au, SWCNTs) significantly impacting heat dissipation and temperature distribution within the microfluidic conduit. Higher nanoparticle concentrations increase liquid viscosity, reducing velocity inside the conduit; however, a magnetic field can reverse this effect. …”
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Advances in Surface-Enhanced Raman Spectroscopy for Therapeutic Drug Monitoring by Huasheng Lai, Xinlan Wang, Menghan Qi, Hao Huang, Bingqiong Yu

“…We discuss the challenges faced by SERS for TDM, such as substrate signal reproducibility and matrix interference from complex biological samples, and explore solutions like digital colloid-enhanced Raman spectroscopy, enrichment detection strategies, microfluidic SERS, tandem instrument technologies, and machine learning-enabled SERS. …”
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