Time series segmentation for recognition of epileptiform patterns recorded via microelectrode arrays in vitro. by Gabriel Galeote-Checa, Gabriella Panuccio, Angel Canal-Alonso, Bernabe Linares-Barranco, Teresa Serrano-Gotarredona

“…The algorithms were validated validated against epileptiform activity induced by 4-aminopyridine in mouse hippocampus-cortex (CTX) slices and recorded via microelectrode array, as a case study. The ZdensityRODE algorithm showcased a precision and recall of 93% for ictal event detection and 42% precision for interictal event detection, while the AMPDE algorithm attained a precision of 96% and recall of 90% for ictal event detection and 54% precision for interictal event detection. …”
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Simultaneous recording of neuronal discharge and calcium activity reveals claustrum-cortex neurosynchrony under anesthesia by Penghui Fan, Rujin Zhang, Guihua Xiao, Yilin Song, Chaowei Zhuang, Lekang Yuan, Fan Mo, Botao Lu, Zhaojie Xu, Yiding Wang, Jinping Luo, Mixia Wang, Weidong Mi, Jiangbei Cao, Qionghai Dai, Xinxia Cai

Subjects: “…Microelectrode array…”
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New Long-Term Use Solid Bismuth Microelectrode Arrays for Rapid and Sensitive Determination of Sunset Yellow in Isotonic Beverages and Water Samples by Adsorptive Stripping Voltammetry by Mieczyslaw Korolczuk, Iwona Gęca, Artur Mazurek, Paulina Mrózek

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Multi-channel microelectrode arrays for detection of single-cell level neural information in the hippocampus CA1 under general anesthesia induced by low-dose isoflurane by Ruilin Hu, Penghui Fan, Yiding Wang, Jin Shan, Luyi Jing, Wei Xu, Fan Mo, Mixia Wang, Yan Luo, Ying Wang, Xinxia Cai, Jinping Luo

“…In this research, four-shank 32-channel implantable microelectrode arrays (MEAs) were developed for the real-time recording of single-cell level neural information in rat hippocampal CA1. …”
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Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model by Fabiana Santana Kragelund, Konstantinos Spiliotis, Marco Heerdegen, Tina Sellmann, Henning Bathel, Anika Lüttig, Angelika Richter, Jens Starke, Rüdiger Köhling, Denise Franz

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NeuTox 2.0: A hybrid deep learning architecture for screening potential neurotoxicity of chemicals based on multimodal feature fusion by Xudi Pang, Xuejun He, Ying Yang, Ling Wang, Yuzhen Sun, Huiming Cao, Yong Liang

“…Four datasets were used to profile neurotoxicity; these were related to blood–brain barrier permeability, neuronal cytotoxicity, microelectrode array–based neural activity, and mammalian neurotoxicity. …”
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Extracellular Recordings of Patterned Human Pluripotent Stem Cell-Derived Cardiomyocytes on Aligned Fibers by Junjun Li, Itsunari Minami, Leqian Yu, Kiyotaka Tsuji, Minako Nakajima, Jing Qiao, Masato Suzuki, Ken Shimono, Norio Nakatsuji, Hitetoshi Kotera, Li Liu, Yong Chen

“…To create tissue-like constructs of CMs for extracellular monitoring, we placed aligned fibers (AFs) on the surface of a microelectrode array and then seeded hiPSC-CMs for subsequent monitoring for 14 days. …”
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Microelectrothermoforming (μETF): one-step versatile 3D shaping of flexible microelectronics for enhanced neural interfaces by Dong Hyeon Lee, Younghoon Park, Yoon Seo, Hannah Noh, Hyunbeen Jeong, Jongmo Seo, Min-Ho Seo, Kyungsik Eom, Joonsoo Jeong

“…Abstract Increasing the proximity of microelectrode arrays (MEA) to targeted neural tissues can establish efficient neural interfaces for both recording and stimulation applications. …”
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Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings by Keivan Rahmani, Yang Yang, Ethan Paul Foster, Ching-Ting Tsai, Dhivya Pushpa Meganathan, Diego D. Alvarez, Aayush Gupta, Bianxiao Cui, Francesca Santoro, Brenda L. Bloodgood, Rose Yu, Csaba Forro, Zeinab Jahed

“…We developed a physics-informed deep learning model to reconstruct iAP waveforms from extracellular recordings recorded from NEAs and Microelectrode arrays (MEAs), demonstrating its potential for non-invasive, long-term, high-throughput drug cardiotoxicity assessments. …”
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Botulinum Toxin Suppression of CNS Network Activity In Vitro by Joseph J. Pancrazio, Kamakshi Gopal, Edward W. Keefer, Guenter W. Gross

“…Murine spinal cord and frontal cortex networks cultured on substrate integrated microelectrode arrays allowed monitoring of spontaneous spike and burst activity with exposure to BoNT serotype A (BoNT-A). …”
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