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681
Conceptualizing Human Microbiota: From Multicelled Organ to Ecological Community
Published 2008-01-01“…The microbiota of a typical, healthy human contains 10 times as many cells as the human body and incorporates bacteria, viruses, archea, protozoans, and fungi. This diverse microbiome (the collective genomes of the microbial symbionts that inhabit a human host) is essential for human functioning. …”
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682
Modulatory effects in circadian-related diseases via the reciprocity of tea polyphenols and intestinal microbiota
Published 2022-05-01“…The two-way relationship between the host’s circadian rhythm and intestinal microbiota confirms the possibility that prebiotics or probiotic can be used to adjust the intestinal environment and microbiome composition to improve the host health. This article reviews the relationship between the host’s circadian rhythm and microbiota and its influence on metabolic diseases. …”
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683
Sarcopenia and cachexia: molecular mechanisms and therapeutic interventions
Published 2025-01-01“…This review discusses the muscle microenvironment's changes contributing to these conditions, recent therapeutic approaches like lifestyle modifications, small molecules, and nutritional interventions, and emerging strategies such as gene editing, stem cell therapy, and gut microbiome modulation. We also address the challenges and opportunities of multimodal interventions, aiming to provide insights into the pathogenesis and molecular mechanisms of sarcopenia and cachexia, ultimately aiding in innovative strategy development and improved treatments.…”
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684
Autoimmune Hepatitis—Immunologically Triggered Liver Pathogenesis—Diagnostic and Therapeutic Strategies
Published 2019-01-01“…Current experimental investigations of T cell-mediated autoimmune pathways and analysis of changes within the intestinal microbiome might advance our knowledge on the pathogenesis of AIH and trigger a spark of hope for novel therapeutic strategies.…”
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685
Selective Induced Altered Coccidians to Immunize and Prevent Enteritis
Published 2016-01-01“…Microbiomic flora in digestive tract is pivotal to the state of our health and disease. …”
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686
Nutrition and Helicobacter pylori: Host Diet and Nutritional Immunity Influence Bacterial Virulence and Disease Outcome
Published 2016-01-01“…Lastly, we will discuss how micronutrient availability or alterations in the gastric microbiome may exacerbate negative disease outcomes associated with H. pylori colonization.…”
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687
Characterizing the omics landscape based on 10,000+ datasets
Published 2025-01-01“…In this study, we investigate over ten thousand datasets to understand how proteomics, metabolomics, lipidomics, transcriptomics, and microbiome data vary in specific data characteristics. …”
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688
Would you rather treat? A rare case of Mycobacterium scrofulaceum
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689
Innovative approaches in colorectal cancer screening: advances in detection methods and the role of artificial intelligence
Published 2025-01-01“…First, the importance of the gut microbiome in CRC progression is discussed, highlighting how specific microbial alterations can serve as biomarkers for early detection, potentially enhancing diagnostic accuracy when combined with traditional screening methods. …”
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690
Combination of Oxalobacter Formigenes and Veillonella Parvula in Gastrointestinal Microbiota Related to Bile-Acid Metabolism as a Biomarker for Hypertensive Nephropathy
Published 2022-01-01“…The human microbiome is a mixed group of microorganisms, which individually consists of 10–100 trillion symbiotic microbial cells. …”
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691
Iron Homeostasis Dysregulation, Oro-Gastrointestinal Microbial Inflammatory Factors, and Alzheimer’s Disease: A Narrative Review
Published 2025-01-01“…Emerging evidence highlights the pivotal roles of iron homeostasis dysregulation and microbial inflammatory factors in the oral and gut microbiome as potential contributors to the pathogenesis of AD. …”
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692
A quantitative prediction method utilizing whole omics data for biosensing
Published 2025-01-01“…Application of OmicSense to single-cell transcriptome, metabolome, and microbiome datasets confirmed high prediction performance (r > 0.8), suggesting applicability to diverse scientific fields. …”
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693
Comparative analysis of grape berry microbiota uncovers sour rot associates from a Maryland vineyard.
Published 2025-01-01“…It is thus imperative to investigate its role alongside that of other identified core microbiomes in sour rot development. Candida and Pichia were also consistent genera in infected berries. …”
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694
Comparative analysis of antibiotic resistance genes between fresh pig manure and composted pig manure in winter, China.
Published 2025-01-01“…Antibiotic resistance is a critical global public health issue. The gut microbiome acts as a reservoir for numerous antibiotic resistance genes (ARGs), which influence both existing and future microbial populations within a community or ecosystem. …”
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695
Exploring novel pharmacological trends: Natural compounds in dry eye disease management
Published 2024-09-01“…Other strategies, including polyherbal eye drops, liposomal eyelid sprays, and microbiome-supporting solutions offer alternative therapeutic avenues. …”
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696
New insights into anti-depression effects of bioactive phytochemicals
Published 2025-02-01“…Additionally, we summarize the potential mechanisms by which these phytochemicals prevent depression, including regulating neurotransmitters and their receptors, the HPA axis, inflammatory responses, managing oxidative stress, neuroplasticity, and the gut microbiome. Phytochemicals exert therapeutic effects through multiple pathways and targets, making traditional Chinese medicine (TCM) a promising adjunctive antidepressant for the prevention, alleviation, and treatment of depression. …”
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697
Intratumoral microbiota, fatty acid metabolism, and tumor microenvironment constitute an unresolved trinity in colon adenocarcinoma
Published 2025-01-01“…Here, we analyzed intratumoral microbiome samples and matched host transcriptome samples from 420 patients with COAD in The Cancer Genome Atlas (TCGA). …”
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698
Complex Probiotics Suppress Inflammation by Regulating Intestinal Metabolites in Kittens
Published 2025-01-01“…The juvenile period is a critical stage of cat growth; in particular, the metabolic activity of the intestinal microbiome of kittens is critical for processing nutrients and supporting overall health. …”
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699
Understanding the Impact of Omega-3 Rich Diet on the Gut Microbiota
Published 2016-01-01“…Among exogenous factors affecting gut microbiome, diet appears to have the largest effect. …”
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700
Inflammation, impaired motor function and visceral hypersensitivity: the main mechanisms of functional disorders of the gastrointestinal tract (materials of the Expert Council and...
Published 2022-05-01“…The pathogenesis of the most common functional diseases of the gastrointestinal tract — functional dyspepsia (FD) and irritable bowel syndrome (IBS) is multifactorial and includes motor disorders of various parts of the gastrointestinal tract, visceral hypersensitivity, changes in the intestinal microbiome, impairment of the permeability of the protective barrier, low-grade inflammation of the gastrointestinal mucosa, etc. …”
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