Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency by Jungnam Lee, Naweed Mohammad, Kyudong Han, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L. Brantly, Karina A. Serban, Karina A. Serban

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Enhancement of anti‐sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2‐targeted CAR by Pui Yeng Lam, Natacha Omer, Josh K. M. Wong, Cui Tu, Louisa Alim, Gustavo R. Rossi, Maria Victorova, Hannah Tompkins, Cheng‐Yu Lin, Ahmed M. Mehdi, Amos Choo, Melissa R. Elliott, Elaina Coleborn, Jane Sun, Timothy Mercer, Orazio Vittorio, Lachlan J. Dobson, Alexander D. McLellan, Andrew Brooks, Zewen Kelvin Tuong, Seth W. Cheetham, Wayne Nicholls, Fernando Souza‐Fonseca‐Guimaraes

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2024 update of the AGIHO guideline on diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients with solid tumours and hematological malignan... by Michael Sandherr, Jannik Stemler, Enrico Schalk, Tessa Hattenhauer, Marcus Hentrich, Bernd Hertenstein, Christian Hohmann, Sibylle C. Mellinghoff, Rebekka Mispelbaum, Christina Rieger, Martin Schmidt-Hieber, Rosanne Sprute, Guenter Weiss, Oliver A. Cornely, Larissa Henze, Cornelia Lass-Floerl, Gernot Beutel, Annika Y. Classen, Noemi F. Freise, Meinolf Karthaus, Philipp Koehler, Robert Krause, Julia Neuhann, Hans Martin Orth, Olaf Penack, Markus Schaich, Karsten Spiekermann, Sebastian Voigt, Florian Weissinger, Elena Busch

“…Emerging aspects in epidemiology, diagnostic procedures, risk stratification, first-line antimicrobial treatment, empiric antifungal treatment and the duration of antimicrobial treatment are discussed and rated on evidence-based strength of recommendation and quality of evidence as described by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). By this, the aim of this guideline is to provide evidence-based recommendations on the management of febrile neutropenia in cancer patients for the practicing clinician.…”
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5-Lipoxygenase-Dependent Recruitment of Neutrophils and Macrophages by Eotaxin-Stimulated Murine Eosinophils by Ricardo Alves Luz, Pedro Xavier-Elsas, Bianca de Luca, Daniela Masid-de-Brito, Priscila Soares Cauduro, Luiz Carlos Gondar Arcanjo, Ana Carolina Cordeiro Faria dos Santos, Ivi Cristina Maria de Oliveira, Maria Ignez Capella Gaspar-Elsas

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Active case detection and treatment of malaria in pregnancy using LAMP technology (LAMPREG): a pragmatic randomised diagnostic outcomes trial—study protocol by Mekonnen Teferi, Claire Kamaliddin, Hiwot Tilahun, Rediet Fikru Gebresenbet, Zelalem Mekonnen Bekele, Banchamlak Tegegne, Delenasaw Yewhalaw, Abebe Genetu Bayih, Dylan R Pillai, Filmona Mekuria, Getaneh Alemu, Beka Raya, Omar Abdullah, Taye Teka, James Cheaveau, Ruth Legese, Hiwot Asmerom, Ermias Hundito, Ebrahim Nursefa, Samuel Ayele

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Staphylococcus aureus-specific TIGIT+ Treg are present in the blood of healthy subjects – a hurdle for vaccination? by Jonah Clegg, Jonah Clegg, Malgorzata E. Mnich, Malgorzata E. Mnich, Alberto Carignano, Giovanni Cova, Simona Tavarini, Chiara Sammicheli, Bruna Clemente, Megan Smith, Megan Smith, Emilio Siena, Monia Bardelli, Michela Brazzoli, Fabio Bagnoli, Rachel M. McLoughlin, Elisabetta Soldaini

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Comparative Analysis of Adverse Drug Reactions Associated with Fluoroquinolones and Other Antibiotics: A Retrospective Pharmacovigilance Study by Alshareef H, Alenzi KA, Albalawi BR, Alanazi RM, Albalawi NS, Alasoufi WS, Alqifari S, Ahmed R, Ali MAS

“…Hanan Alshareef,1 Khalidah A Alenzi,2 Budor R Albalawi,3 Rinas M Alanazi,3 Nawal S Albalawi,3 Wedad Saleem Alasoufi,3 Saleh Alqifari,1 Rehab Ahmed,4 Mostafa AS Ali1 1Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; 2Transformation and Business Development, Tabuk Health Cluster, Tabuk, Saudi Arabia; 3Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia; 4Division of Microbiology, Immunology and Biotechnology, Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi ArabiaCorrespondence: Hanan Alshareef, Pharmacy Practice Department, Faculty of Pharmacy, University of Tabuk, Tabuk, Saudi Arabia, Email halsharef@ut.edu.saBackground: Fluoroquinolones (FQs) are among the most popular antimicrobials that are highly effective against various infections. …”
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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

“…Yinshuang Zou,1– 3,* Yaji Yang,1,3,* Jianye Yang,1,3 Yanhao Zhang,4 Chen Zhao,1,3 Leilei Qin,1,3 Ning Hu1,3 1Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Orthopedics, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, 434000, People’s Republic of China; 3Laboratory of Orthopedics, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Army Medical University, Chongqing, 400038, People’s Republic of China*These authors contributed equally to this workCorrespondence: Leilei Qin; Ning Hu, Email qinleilei@stu.cqmu.edu.cn; huning@cqmu.edu.cnBackground: Diagnosing chronic periprosthetic joint infection (PJI) is challenging. …”
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Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation by Grace M Turner, Melanie Calvert, Sue Jowett, Robbie Foy, Jonathan Mant, Sarah Tearne, Lou Atkins, Rachael Jones, Smitaa Patel, Phillip Collis

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Serum levels of Wnt5a in Egyptian women with obesity and their association with toll like receptor 2 Arg753Gln gene polymorphism in a pilot case control study of obesity as a state... by Shaimaa H. Fouad, Mai Eldeeb, Shereen A. Baioumy, Sara I. Taha, Rehab Ali Ibrahim, Aya Elgendy, Azza Omran, Marwa Hamdy, Raed A. Alharbi, Abdulmajeed A. A. Sindi, Sylvia W. Roman

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Performance of HPV E4 and p16INK4a biomarkers in predicting regression of cervical intraepithelial neoplasia grade 2 (CIN2): protocol for a historical cohort study by David Jenkins, Mark H Stoler, Anne Hammer, Torben Steiniche, Lone Kjeld Petersen, Patti E Gravitt, Rikke Kamp Damgaard, Maurits NC de Koning, Wim GV Quint, John Doorbar, Johnny Kahlert

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12 Weeks of Combined Endurance and Resistance Training Reduces Innate Markers of Inflammation in a Randomized Controlled Clinical Trial in Patients with Multiple Sclerosis by Nathalie Deckx, Inez Wens, Amber H. Nuyts, Niel Hens, Benedicte Y. De Winter, Gudrun Koppen, Herman Goossens, Pierre Van Damme, Zwi N. Berneman, Bert O. Eijnde, Nathalie Cools

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Massive subcutaneous filariosis by Filaria martis in beech marten (Martes foina) in Italy by Giovanni Sgroi, Ranju Ravindran Santhakumar Manoj, Ettore Napoli, Nicola D'Alessio, Maria Gabriella Lucibelli, Claudio de Martinis, Esterina De Carlo, Peyman Khademi, Alireza Sazmand, Vincenzo Veneziano

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Incidence of SARS-CoV-2 reinfection in a paediatric cohort in Kuwait by Mohammad Alghounaim, Saadoun Bin-Hasan, Fatemah Alhaddad, Ali Abdulkareem, Danah Alsharrah, Abdullah Alkandari, Mona Al-Ahmad, Hashem Al Hashemi

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The impact of the war in Ukraine on the prevalence of MDR/RR-TB in Poland by A. Nowinski, E. Augustynowicz-Kopeć, J. Garnczarek, A. Halicka, M. Koszela, W. Litwiniuk, D. Maj, I. Mazur, J. Niestrój-Ostrowska, R. Podlasin, A. Regulska, M. Wielopolska, J. Wyrwiński, S. Wesołowski, M. Korzeniewska-Koseła

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Evaluation of the Knowledge, Attitudes and Practice of Veterinary Professionals and Senior Animal Health Students in Central Gondar Zone, Gondar, Ethiopia: Antimicrobial Use and Re... by Abibo Wondie Mekonen, Yesuneh Tefera Mekasha, Melaku Getahun Feleke, Atsede Getaneh, Meron Dereje, Misganew Bafe, Sete Nigussie, Achenef Melaku Beyene

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High power impulse magnetron sputtering deposited virucide and antibacterial CrN-Cu films and the durability of the antimicrobial activity by Santiago Domínguez-Meister, Janire Mediavilla, Anastasia Dianova, Noelia Álvarez, Sara Insausti, Edurne Rujas, Jose L. Nieva, Marta Brizuela, Iñigo Braceras

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Role of Cathepsin S in Periodontal Inflammation and Infection by S. Memmert, A. Damanaki, A. V. B. Nogueira, S. Eick, M. Nokhbehsaim, A. K. Papadopoulou, A. Till, B. Rath, S. Jepsen, W. Götz, C. Piperi, E. K. Basdra, J. A. Cirelli, A. Jäger, J. Deschner

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Malaria and Geohelminthiasis Coinfections in Expectant Women: Effect on Maternal Health and Birth Outcomes in a Malaria Endemic Region in Kenya by Wekesa Antony Wanyonyi, Chrispinus Siteti Mulambalah, David H. Mulama, Elizabeth Omukunda, Darwin Injete Siteti

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Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

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