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161
Review of Biological Network Data and Its Applications
Published 2013-12-01“…Various types of large-scale biological datasets have been collected and analyzed with high-throughput technologies, including DNA microarray, next-generation sequencing, and the two-hybrid screening system, for this purpose. …”
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162
Species-Related Differences in the Proteome of Rat and Human Pancreatic Beta Cells
Published 2015-01-01“…Human cells also expressed more heat shock proteins and radical scavenging systems: apart from SOD2, they expressed high levels of H2O2-scavenger peroxiredoxin 3 (PRDX3), confirmed by microarray, Western blotting, and microscopy. Besides conferring lower susceptibility to oxidative stress to human cells PRDX3 might also play a role in physiological redox regulation as, in rat, its expression was restricted to a beta cell subset with higher metabolic glucose responsiveness. …”
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163
The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degener...
Published 2010-01-01“…To further investigate their contribution to neurodegenerative diseases, we have analyzed the association of HSP27 with pathological lesions of tauopathies. Microarray and immunoblot analysis revealed that HSP27 is enhanced at the mRNA and protein levels in affected brains, and that it is associated with astrocytic pathology. …”
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164
MPO Expression of Background Neutrophils in MPO Negative Acute Promyelocytic Leukemia, An Easy Clue to Corroborate a Challenging Diagnosis: A Case Report and Review of Literature
Published 2023-01-01“…The identification of MPO deficiency based on genetic testing would involve at the least a MPO gene scanning with NGS, followed by microarray to identify somatic uniparental disomy in heterozygotes. …”
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165
Selective Phenome Growth Adapted NK Model: A Novel Landscape to Represent Aptamer Ligand Binding
Published 2017-01-01“…Comparison to empirical aptamer microarray data shows that our theoretical fitness landscapes more accurately represent aptamer ligand binding than other theoretical models. …”
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166
Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome
Published 2017-01-01“…She had negative autoantibodies and no signs of insulin resistance and her monogenic diabetes genetic testing was negative. Microarray study using WHS probe confirmed deletion of 4p chromosome. …”
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167
Calibration of Surface Plasmon Resonance Imager for Biochemical Detection
Published 2012-01-01“…Second, bacteriophage (T4-phage) can be physisorbed on gold microarray spots for bacteria detection. The kinetic physisorption of different concentrations of T4-phages can be observed in real time. …”
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168
Pathway Detection from Protein Interaction Networks and Gene Expression Data Using Color-Coding Methods and A* Search Algorithms
Published 2012-01-01“…With the large availability of protein interaction networks and microarray data supported, to identify the linear paths that have biological significance in search of a potential pathway is a challenge issue. …”
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169
Ultraviolet Radiation and the Slug Transcription Factor Induce Proinflammatory and Immunomodulatory Mediator Expression in Melanocytes
Published 2012-01-01“…In the present studies we examined the possibility that UVR-exposed melanocytes also produce proinflammatory mediators and that Slug is important in this process. Microarray studies revealed that both UVR exposure and Slug overexpression altered transcription of a variety of proinflammatory mediators by normal human melanocytes; some of these mediators are also known to stimulate melanocyte growth and migration. …”
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170
A Fatal Case of Necrotizing Fasciitis Caused by a Highly Virulent Escherichia coli Strain
Published 2016-01-01“…An E. coli strain was isolated from blood and fascia cultures. DNA microarray revealed the presence of 20 virulence genes.…”
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171
Mining 3D Patterns from Gene Expression Temporal Data: A New Tricluster Evaluation Measure
Published 2014-01-01“…Microarrays have revolutionized biotechnological research. …”
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172
A Cross-Study Biomarker Signature of Human Bronchial Epithelial Cells Infected with Respiratory Syncytial Virus
Published 2016-01-01“…In view of those facts publicly available microarray datasets from RSV-infected BEAS-2B cells were analyzed with linear model-based statistics and the platform for functional analysis InnateDB. …”
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173
Effect of Negative Pressure Therapy on the Inflammatory Response of the Intestinal Microenvironment in a Porcine Septic Model
Published 2015-01-01“…Plasma elicited little if any effect which was confirmed by microarray analysis. In this septic swine model NPT appeared to modulate the intestinal microenvironment, facilitating an early robust, yet transient, host defense mediated by M1 and M2 macrophages. …”
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174
Endometriosis Gene Expression Heterogeneity and Biosignature: A Phylogenetic Analysis
Published 2011-01-01“…Our objective was to characterize the heterogeneous pathological process using parsimony phylogenetics. Gene expression microarray data of ovarian endometriosis obtained from NCBI database were polarized and coded into derived (abnormal) and ancestral (normal) states. …”
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175
A Complete Subspace Analysis of Linear Discriminant Analysis and Its Robust Implementation
Published 2016-01-01“…Extensive experiments on several face images and microarray data sets are conducted to evaluate the proposed algorithm in terms of the classification performance, and experimental results show that our method has smaller standard deviations than other methods in most cases.…”
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176
Antitumor Molecular Mechanism of Chlorogenic Acid on Inducting Genes GSK-3β and APC and Inhibiting Gene β-Catenin
Published 2013-01-01“…The different genes were scanned by the 4*44K mouse microarray chips. The effect of the three genes was confirmed by RT-PCR technique with CGA dosage of 5, 10, and 20 mg/kg. …”
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177
Regeneration of Zebrafish CNS: Adult Neurogenesis
Published 2016-01-01“…Recent technological development of exquisite molecular tools in zebrafish, such as cell ablation, lineage analysis, and novel and substantial microarray, together with advancement in stem cell biology, allowed us to investigate how progenitor cells contribute to the generation of appropriate structures and various underlying mechanisms like reprogramming.…”
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178
Simultaneous Detection of Different MicroRNA Types Using the ZIP-Code Array System
Published 2013-01-01“…Several molecular methods exist for the detection of mature and precursor miRNAs. DNA microarrays are predestinated as a high-throughput method for comprehensive miRNA detection in tumors. …”
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179
MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy
Published 2020-01-01“…Methods. We analyzed microarray datasets GSE95368 derived from the Gene Expression Omnibus (GEO) database. …”
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180
RCSD1-ABL1 Translocation Associated with IKZF1 Gene Deletion in B-Cell Acute Lymphoblastic Leukemia
Published 2015-01-01“…We describe extensive genetic characterization of a case of B-ALL with RCSD1-ABL1 fusion, by using conventional cytogenetic analysis, Fluorescence In Situ Hybridization (FISH) studies, and Chromosomal Microarray Analysis (CMA). The use of CMA resulted in detection of an approximately 70 kb deletion at 7p12.2, which caused a disruption of the IKZF1 gene. …”
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