ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis by Guro E. Lind, Kristine Kleivi, Gunn I. Meling, Manuel R. Teixeira, Espen Thiis-Evensen, Torleiv O. Rognum, Ragnhild A. Lothe

“…The expression of the responding genes was compared with microarray expression data of primary colorectal carcinomas. …”
Get full text

ANALYSIS OF CELLULAR REACTION TO IFN-γ STIMULATION BY A SOFTWARE PACKAGE GeneExpressionAnalyser by A. V. Saetchnikov, M. M. Yatskou, P. V. Nazarov, L. Vallar, V. V. Apanasovich

“…The software package GeneExpressionAnalyser for analysis of the DNA microarray experi-mental data has been developed. The algorithms of data analysis, differentially expressed genes and biological functions of the cell are described. …”
Get full text

HisCoM-PAGE: software for hierarchical structural component models for pathway analysis of gene expression data by Lydia Mok, Taesung Park

“…It can be applied to various types of gene expression data, such as microarray data or RNA sequencing data. We expect that the HisCoM-PAGE software will make our method more easily accessible to researchers who want to perform pathway analysis for survival times.…”
Get full text

Estimating the Proportion of True Null Hypotheses in Multiple Testing Problems by Oluyemi Oyeniran, Hanfeng Chen

“…Using experimental microarray datasets, we demonstrate that the new method provides satisfactory estimate in practice.…”
Get full text

Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury by Shijie Yang, Beibei Yu, Qing Zhang, Yongfeng Zhang, Longhui Fu, Bisheng Zhou, Haining Wu, Jianzhong Li, Shouping Gong

“…Methods We employed microarray and single-cell RNA sequencing (scRNA-seq) to investigate gene expression changes and immune cell dynamics in mice following crush injury at 3 and 7 days post-injury (dpi). …”
Get full text

Application of DNA Array Technology for Diagnostic Microbiology by Stephanie A Booth, Michael A Drebot, Graham A Tipples, Lai King Ng

“…Microarrays or DNA chips have been hailed as the ultimate experimental tool for research, drug discovery and diagnostics. …”
Get full text

Intellectual Disability and Blended Phenotypes: Insights from a Centre in North India by Inusha Panigrahi, Sudha Rao, Shalu Verma Kumar, Divya Kumari, Parminder Kaur

“…A confirmatory diagnosis is facilitated by genetic testing like chromosomal microarray and next generation sequencing. We describe here our cohort of 15 patients: children and adolescents with ID diagnosed by using sequencing technologies and parental segregation studies. …”
Get full text

Cancer Classification Using Pattern Recognition and Computer Vision Techniques by Haddou Bouazza Sara, Haddou Bouazza Jihad

“…The rapid advancement of DNA microarray technology has significantly contributed to the classification of various cancers, particularly leukemia. …”
Get full text

11p15.4 Microdeletion Associates with Hemihypertrophy by Surasak Puvabanditsin, Mehrin Sadiq, Marianne Jacob, Maaz Jalil, Kenya Cabrera, Omer Choudry, Rajeev Mehta

“…The results of whole genome SNP microarray analysis showed approximately 77 Kb interstitial deletion of the short arm of chromosome 11 (11p15.4). …”
Get full text

ENO1 Overexpression in Pancreatic Cancer Patients and Its Clinical and Diagnostic Significance by Hang Yin, Lei Wang, Hai-Lin Liu

“…ENO1 protein expression was detected in tissue microarray of human PDAC and adjacent noncancer tissues. …”
Get full text

Unravelling the Impact of an Additional Sex Chromosome in an Adult Female by Sigin George, Vikas Dagar, Barun Kumar Chakrabarty, N. Nagaraja

“…Interphase fluorescence in situ hybridisation was performed to confirm the diagnosis. Chromosomal microarray, which is a more expensive test, substantiated the presence of additional X chromosomes but failed to detect the presence of low level of mosaicism. …”
Get full text

An Autocatalytic Platform Combining a Nonlinear Hybridization Chain Reaction and DNAzyme to Detect microRNA by Hongbo Zhang, Xiuen Cao, Qubo Zhu

“…Conventional methods for miRNA detection, such as quantitative PCR and microarray analysis, often entail intricate sample preparation and lack the requisite sensitivity to detect low-abundance miRNAs like miRNA-21. …”
Get full text

Genetic Architecture of Transcription and Chromatin Regulation by Kwoneel Kim, Hyoeun Bang, Kibaick Lee, Jung Kyoon Choi

“…DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic signatures. …”
Get full text

A Three-Generation Family with Idiopathic Facial Palsy Suggesting an Autosomal Dominant Inheritance with High Penetrance by Christian Grønhøj Larsen, Mette Gyldenløve, Aia Elise Jønch, Birgitte Charabi, Zeynep Tümer

“…The mode of inheritance of IFP has previously been suggested as autosomal dominant with low or variable penetrance, but the present family indicates an autosomal dominant trait with high or complete penetrance. Chromosome microarray studies did not reveal a pathogenic copy number variation, which could enable identification of a candidate gene.…”
Get full text

Nanomaterials based biosensors applied for detection of aflatoxin B1 in cereals: a review by Loyce Namanya, Emma Panzi Mukhokosi, Ediriisa Mugampoza

“…However, more studies are needed to address the automatic simultaneous detection of various aflatoxins in real samples and a biosensing system that integrates with microarray technology.…”
Get full text

Effect of Trehalose and Trehalose Transport on the Tolerance of Clostridium perfringens to Environmental Stress in a Wild Type Strain and Its Fluoroquinolone-Resistant Mutant by Miseon Park, Wilfrid J. Mitchell, Fatemeh Rafii

“…In a chemically defined medium, trehalose and sucrose supported the growth of the wild type but not that of the mutant. Microarray data and qRT-PCR showed that putative genes for the phosphorylation and transport of sucrose and trehalose (via phosphoenolpyruvate-dependent phosphotransferase systems, PTS) and some regulatory genes were downregulated in the mutant. …”
Get full text

Glycopatterns of Urinary Protein as New Potential Diagnosis Indicators for Diabetic Nephropathy by Hanyu Zhu, Moyan Liu, Hanjie Yu, Xiawei Liu, Yaogang Zhong, Jian Shu, Xinle Fu, Guangyan Cai, Xiangmei Chen, Wenjia Geng, Xiaoli Yang, Minghui Wu, Zheng Li, Dong Zhang

“…The results of urinary protein microarray fabricated by another 48 urine specimens also indicated (GlcNAc)2–4 is a potential indictor to differentiate the patients with diabetic nephropathy from nondiabetic nephropathy. …”
Get full text

Current Trends in the Molecular Classification of Renal Neoplasms by Andrew N. Young, Viraj A. Master, Mahul B. Amin

“…Therefore, novel RCC classification systems based on gene expression should be useful for diagnosis, prognosis, and treatment. Recent microarray studies have shown that renal tumors are characterized by distinct gene expression profiles, which can be used to discover novel diagnostic and prognostic biomarkers. …”
Get full text

Testing Homogeneity in a Semiparametric Two-Sample Problem by Yukun Liu, Pengfei Li, Yuejiao Fu

“…This problem arises naturally from many statistical applications such as test for partial differential gene expression in microarray study or genetic studies for gene mutation. …”
Get full text

COMPUTATIONAL ANALYSIS AND FUNCTIONAL ANNOTATION OF AP2/ERF TRANSCRIPTION FACTOR BINDING SITES IN ARABIDOPSIS THALIANA L. GENOME by O. A. Chernykh, V. G. Levitsky, N. A. Omelyanchuk, V. V. Mironova

“…Functional annotation and microarray data analysis of the genes possessing predicted GCC-boxes elucidated their role in ethylene response.…”
Get full text