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401
TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton
Published 2018-01-01“…To identify the mechanisms underlying this TGFβ-mediated enhancement of lineage commitment, we compared the gene expression profiles of TGFβ1-treated hMSC cultures using DNA microarrays. In total, 1932 genes were upregulated, and 1298 genes were downregulated. …”
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402
Pancreatic Acinar Cells Employ miRNAs as Mediators of Intercellular Communication to Participate in the Regulation of Pancreatitis-Associated Macrophage Activation
Published 2016-01-01“…Exosomal miRNAs were extracted and examined using microarrays. A total of 115 differentially expressed miRNAs were identified, and 30 showed upregulated expression, while 85 displayed downregulated expression. …”
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403
Immunohistochemical Expression of Dual-Specificity Protein Phosphatase 4 in Patients with Colorectal Adenocarcinoma
Published 2015-01-01“…We constructed tissue microarrays and investigated DUSP4 expression by immunohistochemistry. …”
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404
Soil-Borne Microbial Functional Structure across Different Land Uses
Published 2014-01-01“…In a multivariate regression tree analysis of soil physicochemical properties and genes detected by functional microarrays, the main factor that explained the different microbial community functional structures was C : N ratio. …”
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405
A new dimensionality reduction technique based on the Wavelet Transform for cancer classification
Published 2025-01-01“…Although the advent of methylation microarrays such as the HumanMethylation450 platform has greatly reduced the dimensionality of the problem from billions to 450K positions, this data size is still too large to be processed by machine learning algorithms for cancer prediction and classification. …”
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406
Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction
Published 2021-01-01“…Methods. circRNA expression profile of MIN6 cells stimulated with a mix of cytokines, including IL-1β, IFN-γ, and TNF-α, was detected by circRNA microarrays. Four dysregulated circRNAs were validated by qRT-PCR. …”
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407
Cyclooxygenase-2 Expression Is a Predictive Marker for Late Recurrence in Colorectal Cancer
Published 2018-01-01“…Immunohistochemical staining, performed for the presence of COX-2 on tissue microarrays, was analyzed. Results. Forty-six patients showed elevated COX-2 expression, and 52 patients did not. …”
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408
Quantifying intratumoral biomarker heterogeneity in tubo-ovarian high-grade serous carcinoma to optimize clinical translation
Published 2025-01-01“…Markers were stained on tissue microarrays and scored using a continuous or categorical interpretation of staining patterns. …”
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409
MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction
Published 2015-01-01“…Differential gene expression was assessed using microarrays. MI was induced in male C57BL/6 mice randomly assigned to antagomir (n=6) or control group (n=7), while sham group (n=7) had sham operation done. …”
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410
The future of plant lectinology: Advanced technologies and computational tools
Published 2025-01-01“…Techniques such as glycan microarrays allow rapid assessment of lectin specificity across a diverse range of glycans by evaluating interactions with immobilized glycans on solid surfaces. …”
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411
Surface Modification by Combination of Dip-Pen Nanolithography and Soft Lithography for Reduction of Bacterial Adhesion
Published 2018-01-01“…DPN allowed creating microarrays from 1 to 5 µm in diameter on model surfaces that were successfully transferred to the stainless steel 316L surface via microstamping. …”
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412
miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction
Published 2017-01-01“…MI rat model was established by a coronary artery ligation surgery. miRNA expression microarrays were performed and the data were deposited in Gene Expression Omnibus (GEO number GSE95855). …”
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413
Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer
Published 2025-02-01“…Methods: Multiplex immunofluorescence was performed on tumor microarrays and images were analyzed using HALO AI software. …”
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414
Expression and prognostic significance of the m6A RNA methylation regulator HNRNPC in HNSCC
Published 2025-02-01“…Gene Expression Omnibus (GEO), normal and tumor tissue microarrays (TMA), and tumor tissue samples from patients with HNSCC were observed that a high level of HNRNPC expression was closely linked to a poor prognosis among patients. …”
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415
Detection of Complement C1q B Chain Overexpression and Its Latent Molecular Mechanisms in Cervical Cancer Tissues Using Multiple Methods
Published 2022-01-01“…We conducted an integrated analysis of C1QB mRNA expression in cervical cancer using public microarrays and RNA-seq data sets by calculating standard mean differences (SMDs). …”
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416
Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma
Published 2022-01-01“…The aim of the study was to screen the downstream functional genes of THSD7A and explore their functions in ESCC, based on the reported research into THSD7A function and on gene microarrays. Methods. We adopted quantitative reverse-transcription polymerase chain reaction (qRT-PCR) and Celigo high-content screening (HCS) technology to screen the downstream genes of THSD7A. …”
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417
EGFR as a biomarker of smoking status and survival in oropharyngeal squamous cell carcinoma
Published 2019-01-01“…Retrospectively collected tumors were used to construct tissue microarrays (TMAs), which were stained with EGFR, p16, DAPI and Pan-cytokeratin, and digitally quantified. …”
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418
Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma
Published 2018-01-01“…In vivo evaluation of Plexin C1 expression in HCC tissues was accomplished by immunohistochemistry studies in tissue microarrays. Results. A monoclonal antibody, clone PE4, specific to Plexin C1, was generated. …”
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419
Risk of adverse cardiovascular events based on common genetic variants in 8-year follow-up of the LIPIDOGEN2015 population using the polygenic risk score (PRS): study design and me...
Published 2024-08-01“…Material and methods All DNA samples of 1779 patients were genotyped using Infinium Global Screening Array-24+ v3.0 Kit microarrays. The samples were amplified, fragmented, and hybridized to BeadChips. …”
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420
EMC2 suppresses ferroptosis via regulating TFRC in nasopharyngeal carcinoma
Published 2025-02-01“…The levels of endoplasmic reticulum membrane protein complex 2 (EMC2) in NPC tissue microarrays were evaluated by immunohistochemistry, and the prognostic value of EMC2 was analyzed in NPC patients. …”
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