Gene Expression Profiling in Lungs of Chronic Asthmatic Mice Treated with Galectin-3: Downregulation of Inflammatory and Regulatory Genes by Esther López, M. Paz Zafra, Beatriz Sastre, Cristina Gámez, Carlos Lahoz, Victoria del Pozo

“…In a previous study, we demonstrated that treatment of chronic asthmatic mice with gene therapy using plasmid encoding galectin-3 (Gal-3) led to an improvement in Th2 allergic inflammation. Methods. Using a microarray approach, this study endeavored to evaluate the changes produced by therapeutic Gal-3 delivered by gene therapy in a well-characterized mouse model of chronic airway inflammation. …”
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MicroRNA Expression Profiling in Behçet’s Disease by Antonio Puccetti, Andrea Pelosi, Piera Filomena Fiore, Giuseppe Patuzzo, Claudio Lunardi, Marzia Dolcino

“…We aimed to identify miRNA expression signatures associated with BD and to investigate their potential implication in the disease pathogenesis. Methods. miRNA microarray analysis was performed in blood cells of BD patients and healthy controls. miRNA expression profiles were analyzed using Affymetrix arrays with a comprehensive coverage of miRNA sequences. …”
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A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth by Marina R. Good, Monica L. Fernández-Quintero, Wei Ji, Alesandra J. Rodriguez, Julianna Han, Andrew B. Ward, Jenna J. Guthmiller

“…To understand if recent H5N1 viruses are changing their receptor use, we screened recombinant hemagglutinin (HA) from historical and recent 2.3.4.4b H5N1 viruses for binding to distinct glycans bearing terminal sialic acids using a glycan microarray. We find that H5 from A/Texas/37/2024, an isolate from the dairy cow outbreak, has increased binding breadth to core glycans bearing terminal α2,3 sialic acids, the avian receptor, compared to historical and recent 2.3.4.4b H5N1 viruses. …”
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H3K79me3T80ph is a Novel Histone Dual Modification and a Mitotic Indicator in Melanoma by Danielle R. Martinez, Hunter W. Richards, Qiushi Lin, Carlos A. Torres-Cabala, Victor G. Prieto, Jonathan L. Curry, Estela E. Medrano

“…Finally, our analysis of H3K79me3T80ph using a tissue microarray indicates that H3K79me3T80ph marks a subset of primary cutaneous melanomas with metastatic potential indicating that H3K79me3T80ph may identify a subset of invasive melanomas with a more aggressive clinical behaviour.…”
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Prevalence and methodologies for detection, characterization and subtyping of Listeria monocytogenes and L. ivanovii in foods and environmental sources by Jin-Qiang Chen, Patrick Regan, Pongpan Laksanalamai, Stephanie Healey, Zonglin Hu

“…In this review, we (A) described L. monocytogenes and L. ivanovii, world-wide incidence of listeriosis, and prevalence of various L. monocytogenes strains in food and environmental sources; (B) comprehensively reviewed different types of traditional and newly developed methodologies, including culture-based, antigen/antibody-based, LOOP-mediated isothermal amplification, matrix-assisted laser desorption ionization-time of flight-mass spectrometry, DNA microarray, and genomic sequencing for detection and characterization of L. monocytogenes in foods and environmental sources; (C) comprehensively summarized different subtyping methodologies, including pulsed-field gel electrophoresis, multi-locus sequence typing, ribotyping, and phage-typing, and whole genomic sequencing etc. for subtyping of L. monocytogenes strains from food and environmental sources; and (D) described the applications of these methodologies in detection and subtyping of L. monocytogenes in foods and food processing facilities.…”
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TIM‐4 increases the proportion of CD4+CD25+FOXP3+ regulatory T cells in the pancreatic ductal adenocarcinoma microenvironment by inhibiting IL‐6 secretion by Ziyao Wang, Zerong Xie, Yu Mou, Ruiman Geng, Chen Chen, Nengwen Ke

“…Meanwhile, multiple fluorescent immunohistochemical staining was used to study the distribution characteristics of TIM‐4, and through tissue microarrays, we explored its correlation with patient prognosis. …”
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Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis by Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

“…This study aimed to identify the shared diagnostic genes and the associated molecular mechanism between OB and AS. The microarray datasets of OB and AS were obtained from the Gene Expression Omnibus (GEO) database. …”
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New insights into the ferroptosis and immune infiltration in endometriosis: a bioinformatics-based analysis by Lusha Liu, Feifei Han, Naiyi Du, Yakun Liu, Aihong Duan, Shan Kang, Bin Li

“…BackgroundFerroptosis, a recently discovered iron-dependent cell death, is linked to various diseases but its role in endometriosis is still not fully understood.MethodsIn this study, we integrated microarray data of endometriosis from the GEO database and ferroptosis-related genes (FRGs) from the FerrDb database to further investigate the regulation of ferroptosis in endometriosis and its impact on the immune microenvironment. …”
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Bioinformatics and System Biological Approaches for the Identification of Genetic Risk Factors in the Progression of Cardiovascular Disease by Joy Dip Barua, Shudeb Babu Sen Omit, Humayan Kabir Rana, Nitun Kumar Podder, Utpala Nanda Chowdhury, Md Habibur Rahman

“…We developed an analytical approach to reveal the risk factors and their linkages with CVD. We used GEO microarray datasets for the CVD and other risk factors in this study. …”
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Exome-First Approach in Fetal Akinesia Reveals Chromosome 1p36 Deletion Syndrome by Masatake Toshimitsu, Shinichi Nagaoka, Shuusaku Kobori, Maki Ogawa, Fumihiko Suzuki, Takema Kato, Shunsuke Miyai, Rie Kawamura, Hidehito Inagaki, Hiroki Kurahashi, Jun Murotsuki

“…Postnatal whole exome sequencing and subsequent chromosomal microarray identified a 3 Mb deletion of chromosomal region 1p36.33–p36.32. …”
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Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells by Stefanie Hoyer, Kerstin F. Gerer, Isabell A. Pfeiffer, Sabrina Prommersberger, Sandra Höfflin, Tanushree Jaitly, Luca Beltrame, Duccio Cavalieri, Gerold Schuler, Julio Vera, Niels Schaft, Jan Dörrie

“…To determine whether mRNA electroporation had any effect on the whole transcriptome of the DCs, we performed microarray analyses of DCs of 6 different donors. None of 60,000 probes was significantly different between mock-electroporated DCs and MelanA-transfected DCs. …”
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Genome-Wide Identification and Expression Analysis of Amino Acid/Auxin Permease (AAAP) Genes in Grapes (<i>Vitis vinifera</i> L.) Under Abiotic Stress and During Development by Xufeng Guo, Na He, Biying Huang, Chongyao Chen, Yanxia Zhang, Xiaoyu Yang, Jie Li, Zhigang Dong

“…This study identified 60 <i>VvAAAP</i> genes, distributed on 14 chromosomes and classified into eight subfamilies. Microarray and transcriptome data revealed that most <i>VvAAAP</i> genes decrease during development, but <i>VvAAAP7</i> and <i>VvAAAP33</i> gradually increase. …”
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Association of Structural Maintenance of Chromosome-1A Phosphorylation with Progression of Breast Cancer by Sushma Yadav, Claudia M. Kowolik, Daniel Schmolze, Yuan Yuan, Min Lin, Arthur D. Riggs, David A. Horne

“…Immunohistochemical (IHC) staining was conducted using previously validated phospho-SMC1A antibodies on a histological section and tissue microarray (TMA) comprising samples from primary, invasive, and metastatic breast cancer and normal breast tissues. …”
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Evaluation of genetic differences between two autochthonous Spanish cattle breeds by Paola E. Milia, Alberto Cesarani, Clara Diaz, Cristina Meneses, Juan Carlos Parejo, Laura Falchi, Nicolò P. P. Macciotta, Corrado Dimauro

“…A total of 4,137 animals (2,785 ANI, 333 BOC, 127 JAR, 263 MORB and 629 MORC) were genotyped with the Affymetrix Beadchip Microarray HD. After quality control, 30,391 common SNPs were retained. …”
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Genome-wide DNA methylation and mRNA transcription analysis revealed aberrant gene regulation pathways in patients with dermatomyositis and polymyositis by Hui Luo, Honglin Zhu, Ding Bao, Yizhi Xiao, Bin Zhou, Gong Xiao, Lihua Zhang, Siming Gao, Liya Li, Yangtengyu Liu, Di Liu, Junjiao Wu, Qiming Meng, Meng Meng, Tao Chen, Xiaoxia Zuo, Quanzhen Li, Huali Zhang, Xiangxiang Pan

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MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis by Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro Okamoto

“…Abstract The detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA) profiles of serum from pediatric patients (0–6 years of age) with G-PAVMs and after the Fontan procedure without G-PAVMs. …”
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Monosomy 21 Seen in Live Born Is Unlikely to Represent True Monosomy 21: A Case Report and Review of the Literature by Trent Burgess, Lilian Downie, Mark D. Pertile, David Francis, Melissa Glass, Sara Nouri, Rosalynn Pszczola

“…In addition, chromosome microarray analysis (CMA) on fibroblasts showed a mosaic duplication of chromosome region 21q11.2q22.13 with approximately 45% of cells showing three copies of the proximal long arm segment, consistent with the presence of a mosaic ring chromosome 21 with ring instability. …”
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Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

“…NAMPT caused a significant upregulation of 9 genes and downregulation of 3 genes, as analyzed by microarray analysis. Eight of these genes could be confirmed by real-time PCR: NAMPT induced a significant upregulation of EGR1, MMP-1, SYT7, ITPKA, CCL2, NTM, IGF2BP3, and NRP1. …”
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Fetal intracranial hemorrhage in second trimester: An ominous finding even after a normal array by Yu-Hong Long, Si-Qi Wu, Xin Wang, Li-Ping Wu, Yi-Min Xiong, Xin Yang, Feng-Xiang Wei

“…All tests such as karyotyping, chromosomal microarray analysis (CMA), and PCR-cytomegalovirus detection of amniotic fluid, returned negative results. …”
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Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance by Chang-Nim Im, Byeong Mo Kim, Eun-Yi Moon, Da-Won Hong, Joung Whan Park, Sung Hee Hong

“…A radioresistant cell line was established by fractionated ionizing radiation (IR) and assessed by a clonogenic assay, flow cytometry, and Western blot analysis, as well as zymography and a wound healing assay. Microarray was performed to profile global expression and to search for differentially expressed genes (DEGs) in response to IR. …”
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