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201
Prenatal Diagnosis of Rare Familial Unbalanced Translocation of Chromosomes 7 and 12
Published 2015-01-01“…The diagnosis of the anomaly was based on two- and three-dimensional ultrasound and microarray analysis. Ultrasonography findings included fetal microcephaly and alobar holoprosencephaly, dysmorphic face (flat occiput, absent nasal bone, microphthalmia, hypotelorism, and single nostril), and hyperechogenic bowel. …”
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202
Proteomics and Its Current Application in Biomedical Area: Concise Review
Published 2024-01-01“…Various sophisticated techniques are employed in proteomics, including polyacrylamide gel electrophoresis, mass spectrometry analysis, NMR spectroscopy, protein microarray, X-ray crystallography, and Edman sequencing. …”
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203
Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment.
Published 2025-01-01“…Researching the interaction between cuproptosis and allergic rhinitis will likely pave the way for future treatment of this disease.<h4>Methods</h4>A microarray dataset of AR patients and normal controls (GSE43523) were obtained from the Gene Expression Omnibus (GEO) database for differential gene analysis. …”
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204
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis.
Published 2025-01-01“…In our study, we analyzed RA microarray data from the Gene Expression Omnibus (GEO) and focused on cellular senescence genes from the CellAge database. …”
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205
Chidamide Suppresses the Growth of Cholangiocarcinoma by Inhibiting HDAC3 and Promoting FOXO1 Acetylation
Published 2022-01-01“…The present study is aimed at investigating the mechanism underlying the possible antitumor effect of the HDAC inhibitor chidamide (CDM) on cholangiocarcinoma (CCA). Microarray-based gene expression profiling was conducted to predict the expression of HDACs in CCA, which was validated in clinical tissue samples from CCA patients. …”
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206
A Novel 2.3 Mb Microduplication of 9q34.3 Inserted into 19q13.4 in a Patient with Learning Disabilities
Published 2012-01-01“…Chromosomal analysis revealed the karyotype 46,XX,der(19)ins(19;9)(q13.4;q34.3q34.3)pat. Cytogenetic microarray analysis (CMA) identified a ~2.3Mb duplication of 9q, which was confirmed by Fluorescence in situ hybridisation (FISH). …”
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207
Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro
Published 2016-01-01“…Here we examined the effects of allogeneic PHA-stimulated peripheral blood mononuclear cells (PBMCs) on ASCs under ambient (20%) oxygen and “physiological” hypoxia (5% O2). As revealed with microarray analysis ASCs under 20% O2 were more affected by activated PBMCs, which was manifested in differential expression of more than 300 genes, whereas under 5% O2 only 140 genes were changed. …”
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208
MOLECULAR AND GENETIC INSIGHTS OF ROOT-KNOT NEMATODES PATHOGENICITY: A REVIEW
Published 2024-04-01“…Protein analysis and molecular databases help identify down-regulated and up-regulated genes. Microarray technology can provide large-scale gene expression data on plant-nematode interaction, aiding in understanding nematode selection and feeding site alteration, thereby identifying genes controlling cell differentiation and division. …”
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209
Integrating Data Mining, Deep Learning, and Gene Ontology Analysis for Gene Expression-Based Disease Diagnosis Systems
Published 2025-01-01“…The manuscript details the outcomes of a comprehensive study on the application of cluster-bicluster analysis, gene ontology analysis, and convolutional neural network (CNN) for diagnosing cancer and Alzheimer’s disease using gene expression data derived from both DNA microarray experiments and mRNA sequencing. It outlines a conceptual framework and provides a block diagram of the stepwise procedure for analyzing gene expression data, aiming to enhance the accuracy and objectivity of disease diagnosis. …”
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210
Combination of triciribine and p38 MAPK inhibitor PD169316 enhances the differentiation effect on myeloid leukemia cells.
Published 2024-01-01“…To clarify the molecular mechanisms involved in the TCN and PD169316-induced differentiation, we performed microarray analyses using NB4 cells. Pathway analysis using DAVID software indicated that "viral protein interaction with cytokine and cytokine receptor" and "cytokine-cytokine receptor interaction" were enriched with high significance. …”
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211
FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling
Published 2018-01-01“…Chromatin immunoprecipitation PCR analysis and microarray hybridization were performed to uncover the mechanism. …”
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212
Chromosome 3p Inverted Duplication with Terminal Deletion: Second Postnatal Case Report with Additional Clinical Features
Published 2019-01-01“…Family history was noncontributory. Microarray analysis revealed a 5.37 Mb deletion of chromosome bands 3p26.1 to 3p26.3 and a 13.68 Mb duplication of 3p24.3 to 3p26.1. …”
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213
Development of a Confocal Optical System Design for Molecular Imaging Applications of Biochip
Published 2007-01-01“…A novel confocal optical system design and a dual laser confocal scanner have been developed to meet the requirements of highly sensitive detection of biomolecules on microarray chips, which is characterized by a long working distance (wd>3.0 mm), high numerical aperture (NA=0.72), and only 3 materials and 7 lenses used. …”
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214
Analysis of small extracellular vesicles from dried blood spots
Published 2025-01-01“…The protocol proves to be robust, reliable and displays very interesting performances even after several weeks (up to 3 weeks) of storage of the DBS when analyzing the sEVs using protein microarray for the presence of the markers CD9, CD63, CD81, EpCAM, Flotilin-1, CD62E/P, CD142 and CD235a. …”
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215
Persistent Bacteremia from Pseudomonas aeruginosa with In Vitro Resistance to the Novel Antibiotics Ceftolozane-Tazobactam and Ceftazidime-Avibactam
Published 2016-01-01“…The Verigene Blood Culture-Gram-Negative (BC-GN) microarray-based assay (Nanosphere, Inc., Northbrook, IL) was used to investigate underlying resistance mechanism in the P. aeruginosa isolate but CTX-M, KPC, NDM, VIM, IMP, and OXA gene were not detected. …”
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216
Unveiling the prenatal features of HADDS: A case report and literature review
Published 2025-01-01“…HADDS was diagnosed by Whole Exome Sequencing on a family trio (Trio-WES) for recurrent urinary tract infection with dysuria at 6 months of age, with a normal karyotype and chromosomal microarray analysis (CMA). The variant is a de novo shifted code mutation, which expands the pathogenic gene spectrum of EBF3. …”
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217
Dissection of Ire1 functions reveals stress response mechanisms uniquely evolved in Candida glabrata.
Published 2013-01-01“…C. glabrata Ire1 did not cleave mRNAs encoding Hac1 and other bZIP transcription factors identified in the C. glabrata genome. Microarray analysis revealed that the transcriptional response to ER stress is not mediated by Ire1, but instead is dependent largely on calcineurin signaling and partially on the Slt2 MAPK pathway. …”
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218
A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker
Published 2014-01-01“…This was later confirmed on peripheral blood cultures by conventional G-banding, fluorescence in situ hybridisation and microarray analysis. Similar Turner mosaic marker chromosome cases have been previously reported in the literature, with a variable phenotype ranging from the mild “classic” Turner syndrome to anencephaly, agenesis of the corpus callosum, complex heart malformation, and syndactyly of the fingers and toes. …”
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219
Recent Advances in the Pathogenesis of Syndromic Autisms
Published 2009-01-01“…Identifying cryptic chromosomal abnormalities by whole genome microarray analysis can increase the understanding of the neurobiological pathways to autism.…”
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220
Long noncoding RNA-EBIC promotes tumor cell invasion by binding to EZH2 and repressing E-cadherin in cervical cancer.
Published 2014-01-01“…In this study, differentially expressed lncRNAs and mRNAs in cervical cancer and paired peritumoral tissues were detected by transcriptome microarray analysis. We found 708 probe sets of lncRNAs increased and 836 probe sets decreased in CC tissues, while 1288 mRNA differential probe sets increased and 901 mRNA probe sets decreased. …”
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