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181
An Improved Pearson’s Correlation Proximity-Based Hierarchical Clustering for Mining Biological Association between Genes
Published 2014-01-01“…Microarray gene expression datasets has concerned great awareness among molecular biologist, statisticians, and computer scientists. …”
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182
General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles
Published 2011-03-01“…Here we present a simple and integrated bioinformatics analysis approach that assembles a public cancer microarray database with a pathway knowledge base for ascertaining and prioritizing upregulated genes encoding cell surface- or membrane-bound proteins, which could serve imaging targets. …”
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183
Study of Single Nucleotide Polymorphisms Associated with Breast Cancer Patients among Arab Ancestries
Published 2022-01-01“…We examined the exome wide microarray-based biomarkers and screened 243,345 SNPs for their possible significant association with our breast cancer patients. …”
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184
Prenatal Diagnosis of Rare Familial Unbalanced Translocation of Chromosomes 7 and 12
Published 2015-01-01“…The diagnosis of the anomaly was based on two- and three-dimensional ultrasound and microarray analysis. Ultrasonography findings included fetal microcephaly and alobar holoprosencephaly, dysmorphic face (flat occiput, absent nasal bone, microphthalmia, hypotelorism, and single nostril), and hyperechogenic bowel. …”
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185
Proteomics and Its Current Application in Biomedical Area: Concise Review
Published 2024-01-01“…Various sophisticated techniques are employed in proteomics, including polyacrylamide gel electrophoresis, mass spectrometry analysis, NMR spectroscopy, protein microarray, X-ray crystallography, and Edman sequencing. …”
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186
Cuproptosis genes in predicting the occurrence of allergic rhinitis and pharmacological treatment.
Published 2025-01-01“…Researching the interaction between cuproptosis and allergic rhinitis will likely pave the way for future treatment of this disease.<h4>Methods</h4>A microarray dataset of AR patients and normal controls (GSE43523) were obtained from the Gene Expression Omnibus (GEO) database for differential gene analysis. …”
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187
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis.
Published 2025-01-01“…In our study, we analyzed RA microarray data from the Gene Expression Omnibus (GEO) and focused on cellular senescence genes from the CellAge database. …”
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188
Chidamide Suppresses the Growth of Cholangiocarcinoma by Inhibiting HDAC3 and Promoting FOXO1 Acetylation
Published 2022-01-01“…The present study is aimed at investigating the mechanism underlying the possible antitumor effect of the HDAC inhibitor chidamide (CDM) on cholangiocarcinoma (CCA). Microarray-based gene expression profiling was conducted to predict the expression of HDACs in CCA, which was validated in clinical tissue samples from CCA patients. …”
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189
A Novel 2.3 Mb Microduplication of 9q34.3 Inserted into 19q13.4 in a Patient with Learning Disabilities
Published 2012-01-01“…Chromosomal analysis revealed the karyotype 46,XX,der(19)ins(19;9)(q13.4;q34.3q34.3)pat. Cytogenetic microarray analysis (CMA) identified a ~2.3Mb duplication of 9q, which was confirmed by Fluorescence in situ hybridisation (FISH). …”
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190
Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro
Published 2016-01-01“…Here we examined the effects of allogeneic PHA-stimulated peripheral blood mononuclear cells (PBMCs) on ASCs under ambient (20%) oxygen and “physiological” hypoxia (5% O2). As revealed with microarray analysis ASCs under 20% O2 were more affected by activated PBMCs, which was manifested in differential expression of more than 300 genes, whereas under 5% O2 only 140 genes were changed. …”
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191
MOLECULAR AND GENETIC INSIGHTS OF ROOT-KNOT NEMATODES PATHOGENICITY: A REVIEW
Published 2024-04-01“…Protein analysis and molecular databases help identify down-regulated and up-regulated genes. Microarray technology can provide large-scale gene expression data on plant-nematode interaction, aiding in understanding nematode selection and feeding site alteration, thereby identifying genes controlling cell differentiation and division. …”
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192
Integrating Data Mining, Deep Learning, and Gene Ontology Analysis for Gene Expression-Based Disease Diagnosis Systems
Published 2025-01-01“…The manuscript details the outcomes of a comprehensive study on the application of cluster-bicluster analysis, gene ontology analysis, and convolutional neural network (CNN) for diagnosing cancer and Alzheimer’s disease using gene expression data derived from both DNA microarray experiments and mRNA sequencing. It outlines a conceptual framework and provides a block diagram of the stepwise procedure for analyzing gene expression data, aiming to enhance the accuracy and objectivity of disease diagnosis. …”
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193
FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling
Published 2018-01-01“…Chromatin immunoprecipitation PCR analysis and microarray hybridization were performed to uncover the mechanism. …”
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194
Chromosome 3p Inverted Duplication with Terminal Deletion: Second Postnatal Case Report with Additional Clinical Features
Published 2019-01-01“…Family history was noncontributory. Microarray analysis revealed a 5.37 Mb deletion of chromosome bands 3p26.1 to 3p26.3 and a 13.68 Mb duplication of 3p24.3 to 3p26.1. …”
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195
Development of a Confocal Optical System Design for Molecular Imaging Applications of Biochip
Published 2007-01-01“…A novel confocal optical system design and a dual laser confocal scanner have been developed to meet the requirements of highly sensitive detection of biomolecules on microarray chips, which is characterized by a long working distance (wd>3.0 mm), high numerical aperture (NA=0.72), and only 3 materials and 7 lenses used. …”
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196
Analysis of small extracellular vesicles from dried blood spots
Published 2025-01-01“…The protocol proves to be robust, reliable and displays very interesting performances even after several weeks (up to 3 weeks) of storage of the DBS when analyzing the sEVs using protein microarray for the presence of the markers CD9, CD63, CD81, EpCAM, Flotilin-1, CD62E/P, CD142 and CD235a. …”
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197
Persistent Bacteremia from Pseudomonas aeruginosa with In Vitro Resistance to the Novel Antibiotics Ceftolozane-Tazobactam and Ceftazidime-Avibactam
Published 2016-01-01“…The Verigene Blood Culture-Gram-Negative (BC-GN) microarray-based assay (Nanosphere, Inc., Northbrook, IL) was used to investigate underlying resistance mechanism in the P. aeruginosa isolate but CTX-M, KPC, NDM, VIM, IMP, and OXA gene were not detected. …”
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198
Unveiling the prenatal features of HADDS: A case report and literature review
Published 2025-01-01“…HADDS was diagnosed by Whole Exome Sequencing on a family trio (Trio-WES) for recurrent urinary tract infection with dysuria at 6 months of age, with a normal karyotype and chromosomal microarray analysis (CMA). The variant is a de novo shifted code mutation, which expands the pathogenic gene spectrum of EBF3. …”
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199
A Turner Syndrome Patient Carrying a Mosaic Distal X Chromosome Marker
Published 2014-01-01“…This was later confirmed on peripheral blood cultures by conventional G-banding, fluorescence in situ hybridisation and microarray analysis. Similar Turner mosaic marker chromosome cases have been previously reported in the literature, with a variable phenotype ranging from the mild “classic” Turner syndrome to anencephaly, agenesis of the corpus callosum, complex heart malformation, and syndactyly of the fingers and toes. …”
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200
Recent Advances in the Pathogenesis of Syndromic Autisms
Published 2009-01-01“…Identifying cryptic chromosomal abnormalities by whole genome microarray analysis can increase the understanding of the neurobiological pathways to autism.…”
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