Genomic and micro-environmental insights into drug resistance in colorectal cancer liver metastases by Junjie Kuang, Jun Li, Siwei Zhou, Yi Li, Jinbo Lin, Weizhen Huang, Xia Yuan

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Mitigating continuous cropping barriers in tobacco through organic amendments-induced rhizosphere micro-environmental improvement by Jie Huang, Xinyue Wang, Lili Yang, Yuanhuan Li, Bing Xia, Hailin Li, Xiaohua Deng

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Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent. by Fang-Chao Zhu, Jin Sun, Guo-Yong Yan, Jiao-Mei Huang, Chong Chen, Li-Sheng He

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ANN-Based Real-Time Prediction of Heat and Mass Transfer in the Paper-Based Storage Enclosure for Sustainable Preventive Conservation by Bo Han, Fan Wang, Julie Bon, Linda MacMillan, Nick K. Taylor

“…This model was specially designed for 24 h real-time prediction of heat and mass transfer and to simulate the micro-environmental conditions under varying levels of control accuracy over the macro-environment. …”
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Fine‐Scale Variation in Soil Properties Promotes Local Taxonomic Diversity of Hybridizing Oak Species (Quercus spp.) by Felix Zimmermann, Oliver Reutimann, Andri Baltensweiler, Lorenz Walthert, Jill K. Olofsson, Christian Rellstab

“…Here, we extensively sampled a mixed stand of hybridizing white oaks (Quercus petraea and Q. pubescens) near Lake Neuchâtel (Switzerland), where limestone and glacier moraine geologies coexist in proximity, to test whether micro‐environmental conditions can predict taxonomic distribution and genetic admixture. …”
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Diversity of planktonic gastropods from western Baja California Peninsula assessed by 18S rDNA sequences by Ricardo Pérez-Enríquez, Alejandra Arciniega, Noé Díaz-Viloria, Salvador E. Lluch-Cota

“…Differences in community composition between and within sampling sites indicate that planktonic gastropod distribution is not random but probably modulated by micro-environmental processes such as currents or biological events. …”
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Multidimensional Perspective of Sustainable Agroecosystems and the Impact on Crop Production: A Review by Zanele Adams, Albert Thembinkosi Modi, Simon Kamande Kuria

“…It is important to view agroecosystems from a micro-environmental perspective given that they are characterised by a combination of factors, including the interaction of soil–plant–atmosphere conditions, which are largely responsive to human management practices. …”
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Temperature Prediction at Street Scale During a Heat Wave Using Random Forest by Panagiotis Gkirmpas, George Tsegas, Denise Boehnke, Christos Vlachokostas, Nicolas Moussiopoulos

“…The model was trained using data from a low-cost sensor network, meteorological fields calculated by the mesoscale model MEMO, and micro-environmental spatial features. The results show that, although the MEMO temperature predictions achieve high accuracy during nighttime compared to measurements, they exhibit inconsistent trends across sensor locations during daytime, indicating that the model does not fully account for microclimatic phenomena. …”
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Nutritional Status and Anemia among Scheduled Caste Adolescent Girls of District Yamunanagar, Haryana, India by Priyanka Airi Goyal, Indu Talwar

“…Height and weight were measured to calculate Body Mass Index (BMI). Data on micro-environmental factors, socio-economic and demographic variables, and dietary habits were collected through interview-based schedule. …”
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Bridging molecular insights and clinical application: non-coding RNAs, targeted drug delivery, and metastatic breast cancer therapy by Sohini Chakraborty, Satarupa Banerjee

“…Beyond ncRNAs, this review also explores other critical mechanisms of drug resistance in metastatic BC, including efflux transporter activity, target gene mutations, and micro-environmental factors, to mention a few. Moreover, the review also discusses the clinical significance of combination therapies and new therapeutic strategies, including the use of repurposed drugs and the concepts of personalized medicine. …”
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Identification and Diagnosis of Wind Health-Vulnerable Spaces in High-Rise Residential Areas of Xi’an by Jiewen Chen, Siqing Ma, Yuan Meng, Yu Liu, Juan Ren

“…While existing studies mainly focus on macro-scale wind analysis, there is limited exploration of the micro-environmental interactions between wind conditions and human activities. …”
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TROLL 4.0: representing water and carbon fluxes, leaf phenology, and intraspecific trait variation in a mixed-species individual-based forest dynamics model – Part 1: Model descrip... by I. Maréchaux, F. J. Fischer, F. J. Fischer, S. Schmitt, S. Schmitt, S. Schmitt, J. Chave

“…Carbon assimilation and plant water loss are explicitly represented at tree level using coupled photosynthesis and stomatal conductance models, depending on the micro-environmental conditions experienced by trees. Soil water uptake by trees is also modelled. …”
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Study on Dust Hazard Levels and Dust Suppression Technologies in Cabins of Typical Mining Equipment in Large Open-Pit Coal Mines in China by Xiaoliang Jiao, Wei Zhou, Junpeng Zhu, Xinlu Zhao, Junlong Yan, Ruixin Wang, Yaning Li, Xiang Lu

“…Cabins of mining equipment (electric shovels, haul trucks, drills) exhibit unique micro-environmental contamination due to dual-source pollution (external infiltration and internal secondary dust generation), posing severe health risks to miners. …”
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An Effective Oral Nanodelivery Material for Curcumin: Ingenious Utilization of Gastrointestinal Absorption Characteristics by Qiuxu An, Yuanyuan Liu, Guodong Liang, Yuewu Wang, Fengying Liang, Yunyang Bai, Chaolu Eerdun, Riqing Cheng, Haifeng Zhang, Xiaojie Lv

“…This virus-mimetic platform dynamically adapts to micro-environmental demands through charge reversal mechanisms, effectively overcoming sequential biological barriers and providing a robust strategy for oral delivery of hydrophobic therapeutics.…”
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Biodigital Micro-Cellular Mashrabiya: Lattice Architectural Microbial Membranes for Sustainable Built Environments by Yomna K. Abdallah, Alberto T. Estevez

“…This study implements an analytical–descriptive methodology to analyze the key characteristics of a traditional Mashrabiya as an integral sustainable solution and how the proposed micro-cellular biodigital Mashrabiya system can fulfill these criteria to be integrated into the built environment, forging future research trajectories on the bio-/micro-environmental compatibility of this biomaterial-based biodigital Mashrabiya system by understanding these materials’ physical, chemical, and physiological traits and their sustainable value. …”
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Cardiac PDK4 promotes neutrophilic PFKL methylation and drives the innate immune response in diabetic myocardial infarction by Song Yang, Longxin Yan, Lang Chen, Gaijuan Su, Long Yang, Lili Gong, Lihong Liu

“…Through mass spectrometry imaging and phenotype assessment, we ascertained that specific knockout of PDK4 in cardiomyocytes (PDK4fl/flMyh6Cre, male, 6 weeks) led to a reduction in NETosis by restraining micro environmental lactate (LA) production. In addition, the role of LA in promoting NETosis has been further corroborated by in vivo/in vitro experiments involving LA supplementation and its absence. …”
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Atovaquone-induced activation of the PERK/eIF2α signaling axis mitigates metabolic radiosensitisation by Jie Feng, Varun Pathak, Niall M. Byrne, Sarah Chambers, Tongchuan Wang, Rayhanul Islam, Reinhold J. Medina, Jonathan A. Coulter

“…Abstract Background Hypoxia, a key feature of most solid tumours, including head and neck cancer, reduces radiotherapy efficacy by promoting radiation resistance through micro-environmental and genomic alterations. Addressing these resistance mechanisms is crucial, as radiotherapy remains central to managing locally advanced disease. …”
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The dual role of CXCL9/SPP1 polarized tumor-associated macrophages in modulating anti-tumor immunity in hepatocellular carcinoma by Yu Gu, Zhihui Zhang, Hao Huang, Wenyong Zhu, Hongjia Liu, Rongxin Zhang, Nan Weng, Xiao Sun

“…Moreover, CS polarity could serve as a potential indicator of prognostic and micro-environmental status for HCC patients. Based on medical imaging data, we developed a radiomics tool, RCSP (Radiogenomics-based CXCL9/SPP1 Polarity), to assist in non-invasively predicting the CS polarity in HCC patients.ConclusionOur research sheds light on the regulatory roles of SPP1+ TAMs and CXCL9+ TAMs in the micro-environment and provides new therapeutic targets or insights for the reprogramming of targeted macrophages in HCC.…”
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Genetic Variation of Growth Traits and Seed Production in a Patagonian Native Pasture in Semiarid Rangelands Under Different Environmental Settings by Aldana Soledad López, Nicolás Nagahama, Alejandro Aparicio, María Marta Azpilicueta, Verónica Guidalevich, Juan Pablo Angeli, Paula Marchelli

“…The growth and reproductive traits were probably largely influenced by micro-environmental cues (i.e., soil type and moisture), showing predominantly plastic patterns. …”
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Machine learning approaches for EGFR mutation status prediction in NSCLC: an updated systematic review by Liu Haixian, Liu Haixian, Pang Shu, Pang Shu, Li Zhao, Li Zhao, Lu Chunfeng, Lu Chunfeng, Li Lun

“…End-to-end deep-learning models simultaneously perform feature extraction and classification, capturing not only traditional radiomic signatures such as tumour density and texture but also peri-tumoural micro-environmental cues, thereby offering a higher theoretical performance ceiling than hand-crafted radiomics coupled with classical machine learning. …”
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