Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice by Yaoyao Bian, Lili Yang, Zhongli Wang, Qing Wang, Li Zeng, Guihua Xu

“…The study aimed to explore the mechanism by which MS negatively affects C57BL/6N mice, especially the effects caused by MS in the early phase. …”
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Revealing the core suppression effects of various Di (2-ethylhexyl) phthalate exposure on early meiosis progression in postnatal male mice via single-cell RNA sequencing by Baoquan Han, Lei Hua, Shuai Yu, Wei Ge, Cong Huang, Yu Tian, Chunxiao Li, Jiamao Yan, Tian Qiao, Jiachen Guo, Dongliang Lu, Bin Wang, Diya Cai, Yunqi Zhang, Shaolin Liang, Jianjuan Zhao, Qi Hou, Wei Shen, Zhongyi Sun

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Cardiomyocyte-Restricted Deletion of PPARβ/δ in PPARα-Null Mice Causes Impaired Mitochondrial Biogenesis and Defense, but No Further Depression of Myocardial Fatty Acid Oxidation by Jian Liu, Peiyong Wang, Lan He, Yuquan Li, Jinwen Luo, Lihong Cheng, Qianhong Qin, Lawrence A. Brako, Woo-kuen Lo, William Lewis, Qinglin Yang

“…It is unknown whether a PPARα-null background would alter the pathological development in mice with cardiomyocyte-restricted PPARβ/δ deficiency. …”
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Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status? by Chelsea M. Griffith, Lauren N. Macklin, Andrzej Bartke, Peter R. Patrylo

“…Conversely, 3xTg-AD mice, compared to controls, exhibited significantly elevated plasma glucose levels and significantly reduced plasma KB levels. …”
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Immune Modulation Effect of Administration of Rice Bran Extract with Increased Solubility Fermented by <i>Lentinus edodes</i> UBC-V88 in Cyclophosphamide-Treated Mice Model by Gi-Jung Kim, Yelim Jang, Ji-Yoon Hong, Kyoung-Tae Kwon, Dae-Weon Kim, Dae-Jung Kang, Sung-Joo Hwang, Jung-Yun Lee, Emmanouil Apostolidis, Young-In Kwon

“…The potential immunomodulatory effect of fermented rice bran (FRB) and processed rice bran (RB) was evaluated using male BALB/c mice whose immunity was lowered by Cyclophosphamide (CY). …”
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Theasinensin A attenuated diabetic development by restoring glucose homeostasis, improving hepatic steatosis and modulating gut microbiota in high-fat-diet/streptozotocin-induced diabetic mice by Weiqi Xu, Yujie Huang, Wangting Zhou, Yujia Peng, Xuhui Kan, Wei Dong, Guijie Chen, Xiaoxiong Zeng, Zhonghua Liu

“…Therefore, the present study aimed to investigate the influence of TSA on glucose and lipid metabolism and gut microbiota in high-fat-diet/streptozotocin-induced diabetic mice. As result, TSA improved polydipsia, polyphagia and impaired glucose tolerance of diabetic mice, declined the fasting blood glucose and hepatic triglyceride level, and enhanced the expression at mRNA level of insulin receptor substrate, phosphoinositide 3-kinase, protein kinase B and glucagon-like peptide 1 receptor (GLP-1R) in the diabetic liver. …”
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Elimination of olfactory sensory neurons by zinc sulfate inoculation prevents SARS-CoV-2 infection of the brain in K18-hACE2 transgenic mice by Ji-Hun Lee, Eun-Seon Yoo, Na-Won Kim, Won-Yong Shim, Han-Bi Jeong, Dong-Hyun Kim, Young-Jun Park, Sun-Min Seo, Jun-Won Yun, Jun Won Park, Kang-Seuk Choi, Ho-Young Lee, Jun-Young Seo, Ki Taek Nam, Je Kyung Seong, Yang-Kyu Choi

“…These results indicate that early inhibition of the olfactory nerve pathway effectively prevents viral invasion of the brain in K18-hACE2 mice. Our study underscores the significance of the olfactory nerve pathway in the transmission of SARS-CoV-2 to the brain.…”
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Comprehensive three-dimensional microCT and signaling analysis reveal the teratogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on craniofacial bone development in mice by Xiao-ming Wang, Cai-ming Qin, Dou Li, Xin-ran Xu, Xiao-jing Pan, Hui Xue

“…Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in utero can result in osteogenic defect during palatogenesis, but the effects on other craniofacial bones and underlying mechanisms remain to be characterized. By treating pregnant mice with TCDD (40 μg/kg) at the vital craniofacial patterning stages (embryonic day 8.5, 10.5 and 12.5), and scanning and reconstructing the skulls at embryonic day 18.5 using microCT, we found that TCDD exposure at the earlier and later patterning stages induced variable craniofacial malformations, including premature fusion of metopic and coronal sutures, truncated palatal processes of maxillary and palatine bones, as well as opening oriented pterygoid processes. …”
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Forsythia suspensa leaf fermented tea extracts attenuated oxidative stress in mice via the Ref-1/HIF-1α signal pathway and modulation of gut microbiota by Lijuan Li, Yating zhao, Yuxin Ding, Lanze Guo, Ruiyao Dai, Aixiang Chen, Guofeng Duan

“…This study focused on Kunming mice as research subjects and used hydrogen peroxide as an inducer to investigate the antioxidant and anti-inflammatory effects of FSLFT in vivo, as well as its regulatory effects on the intestinal microbiota of mice. …”
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DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge by Victoria Gnazzo, Hanaa Saleh, Ítalo A. Castro, Adrianus C. M. Boon, Amelia K. Pinto, James D. Brien, Carolina B. López

“…We show that the virus-derived oligonucleotide DDO268 enhances antibody and T-cell responses to an influenza A virus (IAV) nucleoprotein mRNA vaccine in mice. DDO268 safely induces local type I interferon production and stimulates dendritic cell activation providing enhanced protection against IAV challenge. …”
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Increased Frequency of Pre&#8211;Pro B Cells in the Bone Marrow of New Zealand Black (NZB) Mice: Implications for aDevelopmental Block in B Cell Differentiation by Zhe-Xiong Lian, Hiroto Kita, Tomoyuki Okada, Tom Hsu, Leonard D. Shultz, Kenneth Dorshkind, Aftab A. Ansari, Susumu Ikehara, Mitsuru Naiki, M. Eric Gershwin

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The Effect of IFN-γ, Alum and Complete Freund Adjuvant on TNP-KLH Induced Ig.G1, IgE and IgG2a Responses in Mice by R. van Ommen, A. E. C. M. Vredendaal, M. de Gooyer, A. van Oudenaren, H. F. J. Savelkoul

“…This is based on the different cytokine production patterns that were observed after in vitro resttmulation of T cells isolated from mice immunized with antigen either adsorbed on alum or emulsified in complete Freund adjuvant (CFA). …”
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Corrigendum to “Hypoglycemic Activity through a Novel Combination of Fruiting Body and Mycelia of Cordyceps militaris in High-Fat Diet-Induced Type 2 Diabetes Mellitus Mice” by Sung-Hsun Yu, Szu-Yu Tina Chen, Wei-Shan Li, Navneet Kumar Dubey, Wei-Hong Chen, Jiunn-Jye Chuu, Sy-Jye Leu, Win-Ping Deng

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Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice by Ying Huang, Haiying Hu, Ling Liu, Jing Ye, Zhen Wang, Bin Que, Wenjing Liu, Ying Shi, Tao Zeng, Lei Shi, Qingwei Ji, Chao Chang, Yingzhong Lin

“…Previous studies demonstrated that both recombinant mice and human IL-35 attenuated atherosclerosis in ApoE-/- mice. …”
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Chronic Exposure to Arsenic in Drinking Water Causes Alterations in Locomotor Activity and Decreases Striatal mRNA for the D2 Dopamine Receptor in CD1 Male Mice by Claudia Leticia Moreno Ávila, Jorge H. Limón-Pacheco, Magda Giordano, Verónica M. Rodríguez

“…Arsenic exposure has been associated with sensory, motor, memory, and learning alterations in humans and alterations in locomotor activity, behavioral tasks, and neurotransmitters systems in rodents. In this study, CD1 mice were exposed to 0.5 or 5.0 mg As/L of drinking water for 6 months. …”
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Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barrier in APP/PS1 mice by Ning Ding, Xin Hao, Yue Zhang, Yanxiang Zhang, Zhigang Li

“…These changes were reversed by MA and probiotics.ConclusionMA can significantly reduce intestinal inflammation and alleviate destruction of the intestinal mucosal barrier in APP/PS1 mice. SCFAs/FFAR3/NF-κB may be important targets through which MA benignly regulates intestinal mucosal barrier function.…”
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Relieving Effect of <i>Artemisia ordosica Krasch</i> Extract on DSS-Induced Colitis by Regulating Immunity, Antioxidant Function, Gut Microbiota, and Bile Acid Metabolism in Mice by Min Jiang, Xuekai Zhang, Xiao Jin, Binlin Shi, Yuanqing Xu, Zheqi Wang

“…The protective effect of AOE on colitis in mice was determined by monitoring key indicators such as body weight, colon length, and survival rate in mice, as well as by assessing the expression of colon-related genes and cytokine levels. …”
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Hypoglycemic polysaccharides from Auricularia auricula and Auricularia polytricha inhibit oxidative stress, NF-κB signaling and proinflammatory cytokine production in streptozotocin-induced diabetic mice by Huan Xiang, Dongxiao Sun-Waterhouse, Chun Cui

“…This is the first report to compare the effectiveness of AAP and APP in combating streptozotocin-induced oxidative stress and diabetes-related changes in mice (body weight, fasting blood glucose, serum insulin, proinflammatory mediator and cytokines, oxidative stress-related products, antioxidant enzymes). …”
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Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model by Shunan Wang, Ming Shen, Bo Pang, Bo Zhou, Yuan Yuan, Mei Lu, Xiangling Deng, Min Yang, Shufang Liu, Qiong Wang, Mei Xue, Qisheng Xia, Zhixin Zhang

Subjects: “…DNAJC12 gene knockout mice…”
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Behavioral and neuronal responses of two mouse species, Mus musculus and Mus spicilegus, to con- and heterospecific olfactory signals by E. V. Kotenkova, A. V. Romashchenko, A. N.  Maltsev

Subjects: “…house mice…”
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