In Vivo Monitoring of Parathyroid Hormone Treatment after Myocardial Infarction in Mice with [Ga]Annexin A5 and [F]Fluorodeoxyglucose Positron Emission Tomography by Sebastian Lehner, Andrei Todica, Yordan Vanchev, Christopher Uebleis, Hao Wang, Tanja Herrler, Carmen Wängler, Paul Cumming, Guido Böning, Wolfgang M. Franz, Peter Bartenstein, Marcus Hacker, Stefan Brunner

“…We tested this technique for therapy monitoring in a murine model of myocardial infarction (MI) including parathyroid hormone (PTH) treatment. MI was induced in mice, and they were assigned to the saline or the PTH group. …”
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Vitamin D and Tinospora cordifolia modulate TLR3 and TLR4 pathways, reduce inflammation, and maintain antimicrobial peptide levels in infected mice by Jamil Ahmad Shobrun, Widyarti Sri, Setiawan Meddy, Rifa’i Muhaimin

“…This study aimed to investigate the effects of vitamin D (VD) and Tinospora cordifolia ethanol extract (TC) on TLR3 and TLR4 receptor protein expression, proinflammatory cytokine (IL1 and IL-6) production, and antimicrobial peptide cathelicidin (CAP) production in CD11b+ cells of mice infected with Escherichia coli. The treatments consisted of administration of VD (0.325 µg/kg bw), TC (100 mg/kg bw), and a combination of both in the same dose for 28 days, followed by induction of E. coli infection on day 29. …”
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Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Colitis in Mice via the Modulation of NF-κB and Nrf2/HO-1 Pathways by Jinke Huang, Jiaqi Zhang, Zhihong Liu, Jing Ma, Yifan Wang, Fengyun Wang, Xudong Tang

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Effects of a Diet Enriched with Polyunsaturated, Saturated, or Trans Fatty Acids on Cytokine Content in the Liver, White Adipose Tissue, and Skeletal Muscle of Adult Mice by Bruno dos Santos, Debora Estadella, Ana Cláudia Losinskas Hachul, Marcos Hiromu Okuda, Mayara Franzoi Moreno, Lila Missae Oyama, Eliane Beraldi Ribeiro, Claudia Maria da Penha Oller do Nascimento

“…This study analyzed the effect of diet enriched with 30% lipids on cytokines content in different tissues. Swiss male mice were distributed into four groups treated for 8 weeks with control (C, normolipidic diet); soybean oil (S); lard (L); and hydrogenated vegetable fat (H). …”
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Dietary Supplemental Glutamine Enhances the Percentage of Circulating Endothelial Progenitor Cells in Mice with High-Fat Diet-Induced Obesity Subjected to Hind Limb Ischemia by Chi-Hsuan Ko, Sung-Ling Yeh, Chiu-Li Yeh

“…This study investigated whether glutamine (GLN) pretreatment can enhance circulating endothelial progenitor cells (EPCs) and attenuate inflammatory reaction in high-fat diet-induced obese mice with limb ischemia. Mice were assigned to a normal control (NC), high-fat control (HC), limb ischemia (HI), and GLN limb ischemia (HG) groups. …”
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Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells by Elena G. Novoselova, Olga V. Glushkova, Sergey M. Lunin, Maxim O. Khrenov, Svetlana B. Parfenyuk, Tatyana V. Novoselova, Mars G. Sharapov, Vladimir I. Novoselov, Evgeny E. Fesenko

“…It was shown that PRDX6 prevented hyperglycemia, lowered the mortality rate, restored the plasma cytokine profile, reversed the splenic cell apoptosis, and reduced the β cell destruction in Langerhans islets in mice with a severe form of alloxan-induced diabetes. …”
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Achyranthes bidentata Polysaccharide along with Anti-IL-5 Antibody Inhibits Allergic Lung Inflammation and Airway Hyperresponsiveness Mice Induced by House Dust Mites by Jian Sun, Shiwei Sheng, Gang Zhao

“…In this study, we constructed chronic allergic asthma mice model induced by house dust mites (HDM) with airway hyperresponsiveness (AHR) and found that anti-IL-5 mAb and ABPS treatment can both decrease inflammatory cells infiltration especially eosinophils and decrease the level of serum IgE and HDM-specific IgG1. …”
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The Optimal Intervention Time of Bone Marrow Mesenchymal Stem Cells in Ameliorating Cardiac Fibrosis Induced by Viral Myocarditis: A Randomized Controlled Trial in Mice by Tingting Wu, Yuan Xie, Jing Huang, Ping Li, Xuliang Wang, Yaoyao Yan, Tianhe Xia, Lei Li, Feng Zhu, Hao Li, Rongzhou Wu

“…On the 1st day, 3rd day, 7th day, and 14th day after BALB/c mice were infected by CVB3, we intravenously injected equivalent BMSCs into the treatment groups. …”
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Green Tea Extract Supplementation Induces the Lipolytic Pathway, Attenuates Obesity, and Reduces Low-Grade Inflammation in Mice Fed a High-Fat Diet by Cláudio A. Cunha, Fábio S. Lira, José C. Rosa Neto, Gustavo D. Pimentel, Gabriel I. H. Souza, Camila Morais Gonçalves da Silva, Cláudio T. de Souza, Eliane B. Ribeiro, Alexandra Christine Helena Frankland Sawaya, Cláudia M. Oller do Nascimento, Bruno Rodrigues, Patrícia de Oliveira Carvalho, Lila M. Oyama

“…The mice were fed ad libitum with chow or high-fat diet and concomitantly supplemented (oral gavage) with 400 mg/kg body weight/day of green tea extract (CG and HG, resp.). …”
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iTRAQ-Based Proteomic Analysis of Visual Cycle-Associated Proteins in RPE of rd12 Mice before and after RPE65 Gene Delivery by Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Shanshan Hua, Minghan Li, Jijing Pang, Jia Qu, Wensheng Li

“…To investigate the iTRAQ-based proteomic changes of visual cycle-associated proteins in RPE of rd12 mice before and after RPE65 gene delivery. Mehtods. …”
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GLP-1 Gene-Modified Human Umbilical Cord Mesenchymal Stem Cell Line Improves Blood Glucose Level in Type 2 Diabetic Mice by Ying Chang, Mingxin Dong, Yan Wang, Haotian Yu, Chengbiao Sun, Xin Jiang, Wei Chen, Xin Wang, Na Xu, Wensen Liu, Ningyi Jin

“…And this cell strain results in lowering blood glucose in type 2 diabetic mice. The results showed that after 3 weeks of intramuscular injection of the new cell line, the fasting blood glucose of type 2 diabetic mice returned to the normal range, and the hypoglycemic effect was maintained within 3 weeks after putting an end to the drug. …”
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Interferon-gamma: A Potent Antiviral Agent Targeting Macrophages Infected with LP-BM5 Murine Leukemia Virus, the Causative Agent of 'AIDS' in Mice by Jens J Kort, Julie L Eiseman

“…LP-BM5 murine leukemia virus (MuLV) infection of C57BL/6 mice and cell lines has been used to optimize therapy directed against macrophages. …”
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Disease Stage-Associated Alterations in Learning and Memory through the Electroacupuncture Modulation of the Cortical Microglial M1/M2 Polarization in Mice with Alzheimer’s Disease by Long Li, Le Li, Jiayong Zhang, Sheng Huang, Weilin Liu, Zhifu Wang, Shengxiang Liang, Jing Tao, Lidian Chen

“…We propose that electroacupuncture at the Shenting and Baihui acupoints could regulate microglial polarization and decrease Aβ plaques to improve learning and memory in mild AD mice.…”
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CircXYLT1 suppresses oxidative stress and promotes vascular remodeling in aging mice carotid artery injury model of atherosclerosis via PTBP1 by Gang Li, Donghui Li, Yajing Li, Bingqi Liu

“…RNA sequencing revealed a significant upregulation of CircXYLT1 in the vascular tissues of aged mice, highlighting its potential role in age-related vascular diseases. …”
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Shenlian (SL) Decoction, a Traditional Chinese Medicine Compound, May Ameliorate Blood Glucose via Mediating the Gut Microbiota in db/db Mice by Rui-xi Sun, Wei-jun Huang, Yao Xiao, Dou-dou Wang, Guo-hua Mu, He Nan, Bo-ran Ni, Xiao-qiang Huang, Hsuan-chuan Wang, Yi-fan Liu, Qiang Fu, Jin-xi Zhao

“…To explore the effect of SL decoction on intestinal microbiota, gut microbiota of mice was analyzed by sequencing the gut bacterial 16S rRNA V3+V4 region and metagenomics. …”
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Effect of Bacillus subtilis JZXJ-7, a Strain Isolated from Shrimp Paste, on Colonic Function and Microbial Community in Mice Infected with Vibrio parahaemolyticus by ZHOU Kui, WANG Rundong, GONG Mengxue, MOU Jingyuan, DENG Yijia, LI Xuepeng, ZHANG Yuhao, LI Jianrong

“…The protective effect of Bacillus subtilis JZXJ-7 (JZXJ-7) on Vibrio parahaemolyticus (Vp) infected mice was investigated. Totally 28 male C57BL/6J mice were randomly divided into four groups: a Vp infection model group (infected with the standard virulence strain ATCC33847), two JZXJ-7 intervention groups (administered at low (106 CFU) and high (108 CFU) doses by gavage), and a control group. …”
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Corrigendum to “Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity” [eBioMedicine 109(2024) 105421] by Md Nazmul Hossain, Yao Gao, Xinrui Li, Liang Zhao, Xiangdong Liu, Jeanene Marie de Avila, Mei-Jun Zhu, Min Du

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Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu by Sathish Sivaprakasam, Pramodh K. Ganapathy, Mohd Omar Faruk Sikder, Moamen Elmassry, Sabarish Ramachandran, Kameswara Rao Kottapalli, Vadivel Ganapathy

“…Here, we have examined the impact of dietary fiber deficiency on luminal microbial composition and transcriptomic profile in colonic epithelium in wild-type (WT) and Slc5a8-null (KO) mice. We fed WT and KO mice with fiber-containing diet (FC-diet) or fiber-free diet (FF-diet) and analyzed the luminal bacterial composition by sequencing 16S rRNA gene in feces. …”
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Anti-Glycemic and Anti-Hepatotoxic Effects of Mangosteen Vinegar Rind from Garcinia mangostana Against HFD/STZ-Induced Type II Diabetes in Mice by Karim Naymul, Jeenduang Nutjaree, Tangpong Jitbanjong

“…This study focuses on anti-glycemic and anti-hepatotoxic effects of mangosteen vinegar rind (MVR) on five weeks high-fat diet (HFD) / single dose streptozotocin (STZ) 30 mg/kg BW induced male ICR diabetic mice. Mice were randomly divided into five groups (n=6), normal control, diabetic control, and diabetic groups treated with MVR 100, 200 mg/kg BW and glibenclamide 60 mg/kg BW for one week. …”
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A Novel Platelet Activating Factor Receptor Antagonist Reduces Cell Infiltration and Expression of Inflammatory Mediators in Mice Exposed to Desiccating Conditions after PRK by Salomon Esquenazi, Jiucheng He, Na Li, Nicolas G. Bazan, Isi Esquenazi, Haydee E. P. Bazan

“…The other twenty mice underwent bilateral PRK and were divided in two additional groups: ten mice remained under normal conditions (NC) and the other ten were exposed to DE. …”
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