Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters by Kit-Leong Cheong, Amanullah Sabir, Suresh Veeraperumal, Franck Quero, Rui Li, Qiaoli Zhao, Karsoon Tan, Saiyi Zhong, Udayakumar Veerabagu

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Effect of Creatine Monohydrate Supplementation on Various Hematological and Serum Biochemical Parameters of Male Albino Mice following Neonatal Hypoxia-Ischemia Encephalopathy by Shahid Iqbal, Nabia Nazir, Quratulane Gillani, Atif Akbar, Furhan Iqbal

“…ALT had higher concentrations in mice feeding on normal diet for 8 (P>0.01) and 12 weeks (P>0.01) following asphyxia and in 12 weeks treatment without asphyxia (P=0.006) when compared with the creatine supplemented mice. …”
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Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process by Guo-Ping Chen, Xiao-Qin Zhang, Tao Wu, Liang Li, Jie Han, Chang-Qing Du

“…The aim of this study was to define whether the enzyme expression in mevalonate pathway is changed in proliferated VSMCs during atherogenic process in diabetic mice. Diabetes was induced in BALB/c mice with streptozotocin (STZ, 50 mg/kg/day for 5 days). …”
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The Protective Effects of 18β-Glycyrrhetinic Acid on Imiquimod-Induced Psoriasis in Mice via Suppression of mTOR/STAT3 Signaling by Haiming Chen, Huazhen Liu, Bin Tang, Yuchao Chen, Ling Han, Jingjie Yu, Yuhong Yan, Chuanjian Lu

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Silencing hepatic PCSK9 via novel chimeric AAV8 mitigates the progression of atherosclerosis by inhibiting inflammation in ApoE−/− mice by Xiaocui Chen, Minghui Sun, Xiang Ma, Yitong Ma, Bangdang Chen

“…Moreover, it significantly lowered serum cholesterol and triglyceride levels while increasing LDL-R level without causing hepatotoxicity in wild-type mice. Additionally, it decreased PCSK9 expression and elevated low-density lipoprotein receptor expression in Apolipoprotein E-deficient mice, leading to early changes in lipid profiles but lacking a sustained impact on circulating lipids. …”
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Electroacupuncture Mitigates Hippocampal Cognitive Impairments by Reducing BACE1 Deposition and Activating PKA in APP/PS1 Double Transgenic Mice by Yinshan Tang, Shujun Shao, Yu Guo, You Zhou, Jin Cao, Anping Xu, Jihong Wu, Zhigang Li, Dulian Xiang

“…In summary, EA treatment might reduce BACE1 deposition in APP/PS1 transgenic mice and regulate PKA and its associated substrates, such as LTP to change memory and learning abilities.…”
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CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis by Aili Wang, Jianling Liu, Zhangwen Li, Ze Qian, Shuo Yang, Shaohua Luo, Jinle Lin, Jian Wu

“…Furthermore, it enhanced pulmonary function while reducing airway inflammation and mucus secretion and inhibited ferroptosis in PM2.5-induced asthmatic mice. Conclusion: CC16 demonstrates promise as a therapeutic agent for PM2.5-induced asthma by modulating ferroptosis and alleviating airway inflammation, thereby providing a novel strategy for asthma management.…”
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Folliculin Interacting Protein 1 (FNIP-1) expression and capillary density in gastrocnemius muscle tissue of mice after biological maturation period by Sinta Ayu Choiriyah, Bambang Purwanto, Viskasari Pintoko Kalanjati, Raden Argarini, Anisah Rosydiyah

“…This study analyzed FNIP-1 and capillary density gastrocnemius muscle of mice using immunohistochemistry. Results: FNIP-1 expression test showed higher in immature mice than mature mice. …”
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Cognitive-Enhancing Effect of a Hydroethanolic Extract of Crinum macowanii against Memory Impairment Induced by Aluminum Chloride in BALB/c Mice by Mohammed S. Jilani, Dexter Tagwireyi, Louis L. Gadaga, Charles C. Maponga, Cosmas Mutsimhu

“…The present study was performed to evaluate the effect of a crude hydroethanolic extract of C. macowanii against aluminum chloride-induced memory impairment in mice using the Morris water maze and the novel object recognition task. …”
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Optogenetic Inhibition of Striatal Neuronal Activity Improves the Survival of Transplanted Neural Stem Cells and Neurological Outcomes after Ischemic Stroke in Mice by Yifan Lu, Lu Jiang, Wanlu Li, Meijie Qu, Yaying Song, Xiaosong He, Zhijun Zhang, Guo-Yuan Yang, Yongting Wang

“…NSCs cultured from transgenic mice expressing fluorescent protein were transplanted into the peri-infarct region of the striatum after transient middle cerebral artery occlusion (tMCAO) surgery. …”
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Nicotinamide Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice through Its Anti-Inflammatory Properties and Modulates the Gut Microbiota by Kai Kang, Yue Sun, Dan Pan, Bing Chang, Li-Xuan Sang

“…This study was aimed at investigating the effect of NAM on the gut microbiota and short-chain fatty acids (SCFAs) in mice with chronic colitis. Colitis was induced in C57BL/6 male mice by administration of 1.5% dextran sulfate sodium (DSS), and the mice were intraperitoneally injected with normal saline (NS) or NAM. …”
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Toxicological Evaluation and Protective Effects of Ethanolic Leaf Extract of Cassia spectabilis DC on Liver and Kidney Function of Plasmodium berghei-Infected Mice by Wiwied Ekasari, Anisah Mahardiani, Nindya T. Putri, Tutik S. Wahyuni, Heny Arwati

“…The research is conducted to find out the toxicity and protective effects of EECS on the liver and kidneys of mice infected with P. berghei ANKA. The acute and subacute toxicity tests were carried out on healthy mice that were given EECS at a dose of 150 mg/kg BW. …”
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Clostridium butyricum attenuates LPS-induced myocardial injury in septic mice by modulating CD4 + CD25 + FOXP3 + Treg by Jinglin Zhao, Liuli Wu, Rupan Zhang, Mei Yuan, Junchao Huang, Xiongfei Jia, Xiaoqin Mao

“…Using 16srRNA technology, we explored how intestinal colonization of Clostridium butyricum over 28 days impacted mice with LPS-induced sepsis. Significant changes were noted in the gut microbiota of the mice, highlighting that C. butyricum can positively influence the immune state in septic myocardial injury models. …”
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Assessment of Global and Local Alterations in Retinal Layer Thickness in Ins2 (Akita) Diabetic Mice by Spectral Domain Optical Coherence Tomography by Andrew W. Francis, Justin Wanek, Mahnaz Shahidi

“…Mean global thickness values were compared between Akita and wild-type mice. Local thickness variations in Akita mice were assessed based on normative values in wild-type mice. …”
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Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice by Yong Xie, Yi Zhang, Zebin Guo, Hongliang Zeng, Baodong Zheng

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miR-224-5p Attenuates Allergic Responses in Mice with Allergic Rhinitis by Modulating the Th1/Th2 Response by Yuxiao Li, Ran An, Mingjin Wu, Jiayan He, Xiaoguang He

“…Conclusion. miR-224-5p attenuates allergic reactions in mice with AR by regulating the Th1/Th2 response.…”
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Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses by Mathias K.-M. Herzog, Audrey Peters, Nizar Shayya, Monica Cazzaniga, Kardokh Kaka Bra, Trisha Arora, Manja Barthel, Ersin Gül, Luca Maurer, Patrick Kiefer, Philipp Christen, Katharina Endhardt, Julia A. Vorholt, Gad Frankel, Markus M. Heimesaat, Stefan Bereswill, Cormac G. M. Gahan, Marcus J. Claesson, Xavier Domingo-Almenara, Wolf-Dietrich Hardt

“…Recent progress has established gnotobiotic mice as valuable models to study how microbiota affect the enteric infections by S. …”
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Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice by Lawrence Coppey, Bao Lu, Craig Gerard, Mark A. Yorek

“…We have demonstrated that treating diet-induced obese (DIO) mice with the vasopeptidase inhibitor ilepatril improved neural function. …”
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LR12 Promotes Liver Repair by Improving the Resolution of Inflammation and Liver Regeneration in Mice with Thioacetamide- (TAA-) Induced Acute Liver Failure by Yongjuan Wang, Xiaoli Xie, Hongqun Liu, Huimin Liu, Huiqing Jiang

“…BALB/c mice were intraperitoneally injected with TAA, followed by intravenous injection of LR12. …”
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Targeting EP2 Receptor Improves Muscle and Bone Health in Dystrophin^−/−/Utrophin^−/− Double-Knockout Mice by Xueqin Gao, Yan Cui, Greg Zhang, Joseph J. Ruzbarsky, Bing Wang, Jonathan E. Layne, Xiang Xiao, Johnny Huard

“…We found that Ep2, Ep4, Cox-2, 15-Pgdh mRNA, and PGE2 were significantly increased in DKO-Hom mice compared to wild-type (WT) mice. The EP2 and EP4 receptors were mainly expressed in CD68⁺ macrophages and were significantly increased in the muscle tissues of both dystrophin^−/− (mdx) and DKO-Hom mice compared to WT mice. …”
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