Comparative proteomic analysis reveals the effects of different fatty acid forms on high-fat diet mice by Jiaping Pan, Huan Wang, Ye Li, Chenyang Lu

“…In this study, the effects of these three LC-PUFAs forms (fish oil for TG and EE, krill oil for PL) on the obese mice were compared, and the proteomic changes that focused on lipid metabolism were evaluated via label-free quantitative proteomics analysis. …”
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The Beneficial Effect of Human Amnion Mesenchymal Cells in Inhibition of Inflammation and Induction of Neuronal Repair in EAE Mice by Jun Shu, Xiaojuan He, Hong Li, Xue Liu, Xuemei Qiu, Tongliang Zhou, Ping Wang, Xiaojie Huang

“…Moreover, CD4+ T cells and CD8+ T cells in the CNS were also significantly decreased in EAE mice after hAMC treatment. In addition, hAMC treatment also promoted the production of neuron-repair factors (NGF, CNTF, and BDNF) in the CNS of EAE mice. …”
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Glymphatic dysfunction and neurodegeneration in ALS: Longitudinal insights from rNLS8 TDP-43 mice by Akram Zamani, Adam K. Walker, David K. Wright

“…Motor function, advanced MRI biomarkers of neurodegeneration, and cortical glymphatic pathway gene expression were assessed together with dynamic contrast-enhanced MRI (DCE-MRI) assessment of glymphatic function at 0-, 3-, 7-, and 21-days after removing mice from Dox feed to initiate cytoplasmic human TDP-43 expression. …”
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Hypothyroidism impairs the circadian rhythmicity of clock genes and proteins involved in gut nutrient absorption in female mice by Ayla Secio-Silva, Paulo Henrique Evangelista-Silva, Felipe Emrich, Letícia Selvatici-Tolentino, Maíza Ferreira, Ana Bárbara de Paula Silva, Bruno Henrique Gomes, Tatienne Neder Figueira-Costa, André Gustavo Oliveira, Rodrigo Antonio Peliciari-Garcia, Francemilson Goulart-Silva, Paula Bargi-Souza

“…This study aimed to evaluate whether hypothyroidism affects the small intestine circadian clock and the daily expression pattern of gut nutrient transporters in female mice. Adult female C57BL/6J mice were subjected to hypothyroidism by the administration of methimazole (0.1%) and sodium perchlorate (1%) in drinking water for 45 days. …”
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Lactate Ameliorates Kainic Acid-Induced Neuroinflammation and Cognitive Impairment via the Chemokine Signaling Pathway in Mice by Chu X, Ge Y, Geng C, Cao P, Wei P, Fu B, Deng Z, Li Y, Zhao G

“…An acute epilepsy model was established in mice by kainic acid induction. The neuronal damage, microglial activation, inflammatory responses, and functional changes were determined by TUNEL assays, immunohistochemistry, quantitative real-time polymerase chain reaction and behavioral tests. …”
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Subcutaneous implantation of tooth germ stem cells over the masseter muscle in mice: An in vivo pilot study by Nosrat Nourbakhsh, Ghazaleh Baniebrahimi, Sahar Talebi, Ardeshir Talebi, Mohammad Hossein Nasr Esfahani, Bijan Movahedian, Maziar Manshayi, Navid Naghdi, Fatemeh Ejeian, Elahe Masaeli, Seyed Ali Mosaddad

“…Objectives: This study aimed to explore the potential of tooth germ stem cells for regenerating tooth-like structures by subcutaneously implanting first molar tooth germ stem cells over the masseter muscle in mice. Methods: Five pairs of house mice, Mus musculus, were selected for mating. …”
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Retraction: Bruton’s tyrosine kinase inhibition attenuates the cardiac dysfunction caused by cecal ligation and puncture in mice by Frontiers Editorial Office

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TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected with Plasmodium berghei ANKA by Elizabeth S. Fernandes, Carolina X. L. Brito, Simone A. Teixeira, Renato Barboza, Aramys S. dos Reis, Ana Paula S. Azevedo-Santos, Marcelo Muscará, Soraia K. P. Costa, Claudio R. F. Marinho, Susan D. Brain, Marcos A. G. Grisotto

“…Noninfected mice were used as controls. Capsazepine or vehicle was given intraperitoneally for 6 days. …”
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Electrical stimulation of the sciatic nerve restores inspiratory diaphragm function in mice after spinal cord injury by Ian Walling, Ian Walling, Sarah Baumgartner, Mitesh Patel, Steven A. Crone, Steven A. Crone, Steven A. Crone

“…Electrical stimulation of limb afferents can increase ventilation in healthy humans and animals, but it is not known if limb afferent stimulation can improve breathing following a cervical injury.MethodsWe stimulated the sciatic nerve while using electromyography to measure diaphragm function in anesthetized mice following a cervical (C2) hemisection spinal cord injury, as well as in uninjured controls. …”
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Effects of orally exposed SiO2 nanoparticles on lipid profiles in gut-liver axis of mice by Kuanhang Li, Zhengzheng Zhou, Yi Cao

“…To this end, we treated mice with 16, 160 or 1600 mg/kg bodyweight SiO2 NPs via intragastric route. …”
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Characterization of a chitinase from Trichinella spiralis and its immunomodulatory effects on allergic airway inflammation in mice by Jia Xu, Ye Yao, Qisheng Zhuang, Zixuan Li, Min Zhang, Shouan Wang, Hongxin Hu, Jianbin Ye

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MICE city ecosystems: building collaboration through information systems – a case study from Thailand by Pattaraporn Warintarawej, Nattaporn Thongsri, Jariya Seksan, Witchuta Marchoo

Subjects: “…MICE city…”
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Prx1-Expressing Progenitor Primary Cilia Mediate Bone Formation in response to Mechanical Loading in Mice by Emily R. Moore, Julia C. Chen, Christopher R. Jacobs

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Amelioration of Nephrotoxicity in Mice Induced by Antituberculosis Drugs Using Ensete ventricosum (Welw.) Cheesman Corm Extract by Abebe Dukessa Dubiwak, Urge Gerema, Daba Abdisa, Ebsa Tofik, Wondu Reta

“…Cheesman corm extract (EVCE) against nephrotoxicity induced by isoniazid and rifampicin in mice. Methods. The present study was conducted on thirty Swiss albino mice randomly allocated into five groups. …”
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Diethylcarbamazine Reduces Chronic Inflammation and Fibrosis in Carbon Tetrachloride- (CCl4-) Induced Liver Injury in Mice by Sura Wanessa Santos Rocha, Maria Eduarda Rocha de França, Gabriel Barros Rodrigues, Karla Patrícia Sousa Barbosa, Ana Karolina Santana Nunes, André Filipe Pastor, Anne Gabrielle Vasconcelos Oliveira, Wilma Helena Oliveira, Rayana Leal Almeida Luna, Christina Alves Peixoto

“…This study investigated the anti-inflammatory effects of DEC on the CCl4-induced hepatotoxicity in C57BL/6 mice. Chronic inflammation was induced by i.p. administration of CCl4 0.5 μL/g of body weight through two injections a week for 6 weeks. …”
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Ameliorative Effects of Polygonatum kingianum Polysaccharides on Lipid Metabolism Disorders and Brain Function Impairments in Obese Mice by XU Yuncong, YAN Qiaojuan, ZHU Chunhua, YANG Shaoqing, LI Houjiang, JIANG Zhengqiang

“…To study the effects of Polygonatum kingianum polysaccharides (PKP) on lipid metabolism disorders and brain function impairments in obese mice, the obese mice were treated with PKP, prepared by enzyme-assisted extraction, for 12 weeks. …”
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Temporal Changes in Phosphatidylserine Expression and Glucose Metabolism after Myocardial Infarction: An in Vivo Imaging Study in Mice by Sebastian Lehner, Andrei Todica, Stefan Brunner, Christopher Uebleis, Hao Wang, Carmen Wängler, Nadja Herbach, Tanja Herrler, Guido Böning, Rüdiger Paul Laubender, Paul Cumming, Ralf Schirrmacher, Wolfgang Franz, Marcus Hacker

“…Annexin- and FDG-PET recordings were obtained in female (C57BL6/N) mice on days 1 to 4 after ligation of the left anterior descending (LAD) artery. [ 68 Ga]annexin A5 uptake (%ID/g) in the LAD artery territory increased from 1.7 ± 1.1 on day 1 to 5.0 ± 3.3 on day 2 and then declined to 2.0 ± 1.4 on day 3 (p = .047 vs day 2) and 1.6 ± 1.4 on day 4 ( p = .014 vs day 2). …”
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Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice by Xiao Meng Zhang, Hao Deng, Jin Dong Tong, Yi Zhen Wang, Xu Chao Ning, Xiu Hong Yang, Fang Qiang Zhou, Hui Min Jin

“…We concluded that oral pyruvate delayed DN progression in db/db mice and the modified Pyr-ORS formula might be an ideal novel therapeutic drink in clinical prevention and treatment of type 2 diabetes and DN.…”
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In Vivo Antiplasmodial Activity of Terminalia mantaly Stem Bark Aqueous Extract in Mice Infected by Plasmodium berghei by Mariscal Brice Tchatat Tali, Cedric Derick Jiatsa Mbouna, Lauve Rachel Yamthe Tchokouaha, Patrick Valere Tsouh Fokou, Jaures Marius Tsakem Nangap, Rodrigue Keumoe, Alvine Ngoutane Mfopa, Issakou Bakarnga-via, Raceline Gounoue Kamkumo, Fabrice Fekam Boyom

“…The aqueous extract from the stem bark of T. mantaly (Tmsbw) was the most potent (IC50=0.809 μg/mL) and was further assessed for acute toxicity and efficacy in Plasmodium berghei-infected mice. Tmsbw was safe in mice with a median lethal dose (LD50) higher than 2000 mg/kg of body weight. …”
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Bifidobacterium breve BB05 alleviates depressive symptoms in mice via the AKT/mTOR pathway by Yanni Pan, Qingling Huang, Yuan Liang, Yuwuqi Xie, Fang Tan, Xingyao Long

“…IntroductionThis study investigates the potential of Bifidobacterium breve BB05 (BB05) in mitigating depressive symptoms in a mouse model of Chronic Unpredictable Mild Stress (CUMS), with fluoxetine as a positive control.Methods and ResultsHigh-dose BB05 (1.0 × 109 CFU/kg, BB05H) significantly reduced anxiety- and depression-like behaviors in CUMS mice, as measured by the open field test, tail suspension test, and forced swim test. …”
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