Age-Dependent Effects of Butyl Benzyl Phthalate Exposure on Lipid Metabolism and Hepatic Fibrosis in Mice by Min-Seo Park, Seonhwa Hwang, Hyun-Bon Kang, Minjeong Ha, Juyeon Park, So-Youn Park, Yong-Joo Park, Min-Hi Park

“…This study investigates the age-dependent effects of butyl benzyl phthalate (BBP) exposure on lipid metabolism in the livers of young and aged mice. Young (2-month-old) and aged (20-month-old) male C57BL/6 mice were exposed to BBP through drinking water at a dose of 169 μg/kg/day for 6 and 4 months, respectively. …”
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Atg5 deficiency in basophils improves metabolism in lupus mice by regulating gut microbiota dysbiosis by Jiaxuan Chen, Quanren Pan, Lu Lu, Xiaorong Huang, Shuting Wang, Xiaoxian Liu, Jiaqi Lun, Xiaowei Xu, Hongyong Su, Fengbiao Guo, Lawei Yang, Liuyong You, Haiyan Xiao, Wenying Luo, Hua-feng Liu, Qingjun Pan

“…Furthermore, Atg5 −/− basophils were transferred to basophil-depleted MRL/MpJ-Fas lpr (MRL/lpr) mice to study their effect on disease metabolism. …”
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Renal Protection by Genetic Deletion of the Atypical Chemokine Receptor ACKR2 in Diabetic OVE Mice by Shirong Zheng, Susan Coventry, Lu Cai, David W. Powell, Venkatakrishna R. Jala, Bodduluri Haribabu, Paul N. Epstein

“…In this study, we utilized ACKR2−/− mice to test whether ACKR2 elimination alters progression of diabetic kidney disease. …”
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Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice by M. Korsgren, L. Källström, L. Uller, T. Bjerke, F. Sundler, C. G. A. Persson, O. Korsgren

“…Hence, we examined effects of MIF immunoneutralization on the development of allergen-induced eosinophilic inflammation as well as on lipopolysaccaride (LPS)-induced neutrophilic inflammation in lungs of mice. Anti-MIF serum validated with respect to MIF neutralizing capacity or normal rabbit serum (NRS) was administered i.p. repeatedly during allergen aerosol exposure of ovalbumin (OVA)-immunized mice in an established model of allergic asthma, or once before instillation of a minimal dose of LPS into the airways of mice, a tentative model of COPD. …”
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Mesenchymal Stem Cells Pretreated with HGF and FGF4 Can Reduce Liver Fibrosis in Mice by Sulaiman Shams, Sadia Mohsin, Ghazanfar Ali Nasir, Mohsin Khan, Shaheen N. Khan

“…For in vivo study we labeled MSCs with PKH-26 and transplanted them into CCl4 injured mice by direct injection into liver. In vitro data showed that cytokines pretreated MSCs significantly reduce LDH level and apoptotic markers in CCl4 injured hepatocytes cocultured model. …”
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Protective Effect of Amphipterygium adstringens Extract on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice by Mario Rodriguez-Canales, Ruben Jimenez-Rivas, Maria Margarita Canales-Martinez, Ana Judith Garcia-Lopez, Nelly Rivera-Yañez, Oscar Nieto-Yañez, Yadira Ledesma-Soto, Luvia Enid Sanchez-Torres, Miriam Rodriguez-Sosa, Luis Ignacio Terrazas, Marco Aurelio Rodriguez-Monroy

“…We investigated the effects of alcoholic extract of A. adstringens (AaEE) in DSS-induced colitis in mice. The protective effect of AaEE was determined at 200 mg/kg by oral gavage for 10 days. …”
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Effect of bacteriocin-producing Pediococcus acidilactici strains on the immune system and intestinal flora of normal mice by Yiteng Qiao, Zhichang Qiu, Fengwei Tian, Leilei Yu, Jianxin Zhao, Hao Zhang, Qixiao Zhai, Wei Chen

“…This study was performed to determine the effects of bacteriocin-producing and non-bacteriocin-producing Pediococcus acidilactici strains on the immune system and intestinal flora of normal mice. Two P. acidilactici strains with antibacterial activity (P. acidilactici CCFM28 and CCFM18) were obtained based on the inhibition-zone assay. …”
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Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6 by Byung Kil Park, Eun-Ah Lee, Hee-Youn Kim, Jun Choul Lee, Koon Soon Kim, Won Hoon Jeong, Ki Young Kim, Bon Jeong Ku, Sang Dal Rhee

“…The liver-specific knockout mice of the Mig-6 gene (Mig-6d/d) showed hepatomegaly and increased hypercholesterolemia. …”
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Voacanga africana-artesunate and Voacanga africana-amodiaquine combinations as effective anti-plasmodial agents in mice by Daniel Ampomah Frimpong, Aliu Moomin, Samuel Asare Nkansah, Aaron Opoku Antwi, Abubakar Ibn Sidik, Paa Kofi Tawiah Adu-Gyamfi, Kwesi Boadu Mensah

“…Results: VA at doses 0 – 300 mg/kg showed no toxicity in the mice, whereas VA at a dose of 3000 mg/kg resulted in the death of mice after 24 h. …”
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Lentinan Attenuates Damage of the Small Intestinal Mucosa, Liver, and Lung in Mice with Gut-Origin Sepsis by Zhongshen Kuang, Tingting Jin, ChangYi Wu, Yanan Zong, Panpan Yin, WangYu Dong, Xue Lin, WeiYan You, Chenlong Zhang, Lijie Wang, Yongying Liu, Shan Ren, Jiangwen Yin, Hang Xu

“…This study is aimed at exploring the effects of lentinan on small intestinal mucosa as well as lung and liver injury in mice with gut-origin sepsis. Cecal ligation and perforation (CLP) were used to construct a mouse model of gut-origin sepsis. …”
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Effect of polysaccharide fractions from Fortunella margarita on the fecal microbiota of mice and SCFA production in vitro by Peilin Chen, Suzhen Lei, Mingyao Tong, Qing Chang, Baodong Zheng, Yi Zhang, Hongliang Zeng

“…This study investigated the in vitro fermentation of FMPS fractions and their effect on the fecal microbiota of mice and short chain fatty acids (SCFAs) production. …”
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Oral Administration of Piperine as Curative and Prophylaxis Reduces Parasitaemia in Plasmodium berghei ANKA-Infected Mice by Shafia Khairani, Nisa Fauziah, Hesti Lina Wiraswati, Ramdan Panigoro, Endang Yuni Setyowati, Afiat Berbudi

“…Then, mice were monitored for parasitaemia, body weight, rectal temperature, survival rate, and clinical parameters. …”
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Evaluation of wound healing activity of the crude extract and solvent fractions of Vahl (Polygonaceae) leaves in mice by Abel Andualem, Kefyalew Ayalew Getahun, Bahiru Tenaw Goshu, Yaschilal Muche Belayneh

“…The healing activity of the crude extract was evaluated using linear incision, circular excision, and burn wound models in mice. Additionally, the activity of solvent fractions was assessed using circular excision wounds in mice. …”
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Analysis of the Renal Protection and Antioxidative Stress Effects of Panax notoginseng Saponins in Diabetic Nephropathy Mice by Wei Mi, Min Yu, Shuying Yin, Yuhan Ji, Tala Shi, Ning Li

“…This study is aimed at investigating the role played by PNS in renal protection and antioxidative stress (OS) in DN mice. Methods. A DN mouse model was constructed, and then low, medium, and high doses of PNS were used to intervene the model group mice. …”
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Para-Phenylenediamine Induces Apoptotic Death of Melanoma Cells and Reduces Melanoma Tumour Growth in Mice by Debajit Bhowmick, Kaushik Bhar, Sanjaya K. Mallick, Subhadip Das, Nabanita Chatterjee, Tuhin Subhra Sarkar, Rajarshi Chakrabarti, Krishna Das Saha, Anirban Siddhanta

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Between-strain differences in hypothermic response in mice after intranasal administration of PtO nanoparticles by D. V. Petrovskii, A. V. Romashchenko, S. Yu. Troitskii, M. P. Moshkin

“…To study the mechanism of this decrease, we compar­ed the respective values for Δtbody following intra­nasal, intravenous and peroral administration of PtO nanoparticles in Balb/c mice. Neither intravenous nor peroral administration had any effect on mouse body temperature. …”
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Exercise training partly ameliorates cardiac dysfunction in mice during doxorubicin treatment of breast cancer by Tytti-Maria Uurasmaa, Pauline Bourdin, Wail Nammas, Shiva Latifi, Heidi Liljenbäck, Antti Saraste, Olli Eskola, Johan Rajander, Anne Roivainen, Helene Rundqvist, Anu Autio, Ilkka Heinonen, Katja Anttila

“…Mice underwent 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography and echocardiography after two and four DOX-doses. …”
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Emodin Ameliorates Intestinal Dysfunction by Maintaining Intestinal Barrier Integrity and Modulating the Microbiota in Septic Mice by Mina Zhang, Bo Lian, Rui Zhang, Yuhong Guo, Jingxia Zhao, Shasha He, Yunjing Bai, Ning Wang, Yan Lin, Xuerui Wang, Qingquan Liu, Xiaolong Xu

“…We found that emodin treatment suppressed the inflammatory response in the intestines of septic mice. Intestinal barrier function was also improved by emodin through enhancing ZO-1 and occludin expression, which prevented the secondary translocation of Escherichia coli. …”
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Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice by Yun Hu, Ting-Ting Cai, Reng-Na Yan, Bing-Li Liu, Bo Ding, Jian-Hua Ma

“…We aimed to explore the local changes of steroidogenesis and spermatogenesis in the testis of db/db mice. Research Design and Methods. We performed single-cell RNA sequencing analysis in the testis of db/db and C57BL/6J mice. …”
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Fine Needle Ethanol Injection Therapy for Human Pancreatic Adenocarcinoma Subcutaneously Xenografted in Nude Mice by Pierre C Gagnon, Marguerite Daumas, Norbert Allieres, Paul D Vincensini, Thierry Ponchon, Etienne Hollande

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