Modulation of Caecal Microbiome in Obese Mice Associated with Administration of Amaranth or Soybean Protein Isolates by Diana Olguín-Calderón, Jorge L. González-Escobar, Rosalva Ríos-Villa, Elena Dibildox-Alvarado, Antonio De León-Rodríguez, Ana P. Barba de la Rosa

“…In turn, Lachnospiraceae bacteria abundance decreased in mice fed the Control-HF and amaranth HF diets, but increased in mice fed the soybean diets. …”
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A H2S Donor GYY4137 Exacerbates Cisplatin-Induced Nephrotoxicity in Mice by Mi Liu, Zhanjun Jia, Ying Sun, Aihua Zhang, Tianxin Yang

“…Here we investigated the effect of GYY4137, a novel slow-releasing H2S donor, on cisplatin nephrotoxicity in mice. Male C57BL/6 mice were pretreated with GYY4137 for 72 h prior to cisplatin injection. …”
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Stabilized β-Catenin Ameliorates ALPS-Like Symptoms of B6/lpr Mice by Xiaoxie Xu, Jun Huang, Mei Zhao, Huanpeng Chen, Jinhua Mo, Xiaoqing Zhou, Qiao Su, Bolan Yu, Zhaofeng Huang

“…In the present study, we introduced β-catTg into lpr/lpr mice and aimed to explore the potential role of stabilized β-catenin (β-catTg) in the development of ALPS-like phenotypes of lpr/lpr mice. …”
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Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice by Sha Yan, Kai Wang, Xiaoying Wang, Aiqun Ou, Feiran Wang, Liming Wu, Xiaofeng Xue

“…The present study aimed to investigate the effect of yeast-fermented wall-broken bee pollen (YB) intervention on ICR mice with MetS induced with a high-fat (HF) diet. …”
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Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice by Kazuki Terada, Tamaki Watanabe, Nobuhiro Yasuno, Toshio Ohtsubo, Shigeru Shibata, Kimiyoshi Ichida, Makoto Hosoyamada

“…In contrast, all Xdh(− / −) mice die due to renal failure before reaching adulthood at 8 weeks of age. …”
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Borneol, a Bicyclic Monoterpene Alcohol, Reduces Nociceptive Behavior and Inflammatory Response in Mice by Jackson Roberto Guedes da Silva Almeida, Grasielly Rocha Souza, Juliane Cabral Silva, Sarah Raquel Gomes de Lima Saraiva, Raimundo Gonçalves de Oliveira Júnior, Jullyana de Souza Siqueira Quintans, Rosana de Souza Siqueira Barreto, Leonardo Rigoldi Bonjardim, Sócrates Cabral de Holanda Cavalcanti, Lucindo José Quintans Junior

“…Additionally, borneol-treated mice reduced the carrageenan-induced leukocytes migration to the peritoneal cavity. …”
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Recovery of Prenatal Baicalein Exposure Perturbed Reproduction by Postnatal Exposure of Testosterone in Male Mice by Sridevi Vaadala, Naveen Ponneri, Venkata Shashank Karanam, Sri Bhashyam Sainath, Pamanji Sreenivasuala Reddy, Ramachandra Reddy Pamuru, Arifullah Mohammed

“…Baicalein (BC), a flavonoid, which lacks the qualities of reproductive health and shows adverse effects, is tested in this study. Inseminated mice were injected with 30, 60, and 90 mg BC/Kg body weight on gestation days 11, 13, 15, and 17. …”
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Effects of White Quinoa Polysaccharide on Regulation of Glucolipid Metabolism in Type 2 Diabetic Mice by Yanqing ZANG, Yingying CHUANG, Changyuan WANG, Yang CAO

“…To investigate the hypoglycemic and lipid-lowering effects of white quinoa polysaccharide (WQP) in type 2 diabetic model mice, the mice were divided into model group, polysaccharide group (800 mg/kg) and normal control group. …”
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Quantitative assessment of brain metabolism in mice using non-contrast MRI at 11.7T by Xiuli Yang, Yuguo Li, Hanzhang Lu, Zhiliang Wei

“…This study outlines a step-by-step method for implementing TRUST and PC MRI in mice at 11.7T scanner. The proposed method yields non-invasive, non-contrast quantitative measurements of global brain metabolism in approximately 20 min, paving the way for broader applications in future pathophysiological studies. • Non-invasive and non-contrast assessment of brain metabolism in mice. • Quantitative measurement of metabolic rate in approximately 20 min.…”
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Extracellular vesicles contribute to the beneficial effects of exercise training in APP/PS1 mice by Oliver K. Fuller, Emma D. McLennan, Casey L. Egan, Nimna Perera, Lauren V. Terry, Jae Pyun, Mariana de Mendonca, Guilherme Defante Telles, Benoit Smeuninx, Emma L. Burrows, Ghizal Siddiqui, Darren J. Creek, John W. Scott, Michael A. Pearen, Pamali Fonseka, Joseph A. Nicolazzo, Suresh Mathivanan, Anthony J. Hannan, Grant A. Ramm, Martin Whitham, Mark A. Febbraio

“…Next, we profiled extracellular vesicles (EVs) and examined whether they may play a role in the protective effects of VET via intranasal administration of EVs, purified from the blood of sedentary (sEV) and/or acutely exercised (eEV) donor wild-type mice into APP/PS1Tg mice. We show that VET reduced resting energy expenditure (REE) and improved cognition in APP/PS1 Tg mice. …”
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Th17: A New Participant in Gut Dysfunction in Mice Infected with Trichinella spiralis by Yu Fu, Wenfeng Wang, Jingjing Tong, Qi Pan, Yanqing Long, Wei Qian, Xiaohua Hou

“…Our data suggest that Th17 cells are increased during acute infection with Trichinella spiralis and IL-17 may contribute to jejunal muscle contractility in mice.…”
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Exercise Training Effects on Inflammatory Gene Expression in White Adipose Tissue of Young Mice by Tracy Baynard, Victoria J. Vieira-Potter, Rudy J. Valentine, Jeffrey A. Woods

“…We aimed to determine the effects of 6 wks of exercise on inflammatory markers in mice concomitantly fed either high-fat (HF) or normal chow (NC) diets in young mice. …”
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Thymic Stromal-Cell Abnormalities and Dysregulated T-Cell Development in IL-2-Deficient Mice by Tannishtha Reya, Hamid Bassiri, Renée Biancaniello, Simon R. Carding

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Decreases in mRNA by an siRNA Complex Do not Alter Blood Pressure in Mice by Su-Min Ji, Young-Bin Shin, So-Yon Park, Hyeon-Ju Lee, Bermseok Oh

“…To validate the function of CASZ1 in blood pressure, we decreased Casz1 mRNA levels in mice by siRNA. Casz1 siRNA reduced mRNA levels by 59% in a mouse cell line. …”
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Development of autonomic innervation at the venous pole of the heart: bridging the gap from mice to human by Fleur Zwanenburg, Thomas A. Bos, Arend D. J. Ten Harkel, Monique C. Haak, Nathan D. Hahurij, Robert E. Poelmann, Conny J. van Munsteren, Lambertus J. Wisse, Nico A. Blom, Marco C. DeRuiter, Monique R. M. Jongbloed

“…Structures related to arrhythmogenicity in humans, such as the ligament/vein of Marshall and the myocardium surrounding the pulmonary veins, become highly innervated during embryonic development in both mice and humans. Conclusion Although early morphological cANS development at sinus venosus-related structures follows a similar sequence in mice and humans, there are substantial differences in the timing of functional establishment and differentiation in sympathetic and parasympathetic phenotypes, which should be taken into account when extrapolating mouse studies of the cANS to humans. …”
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Novel fusion protein REA induces robust prime protection against tuberculosis in mice by Sintayehu Kebede Gurmessa, Han-Gyu Choi, Yong Woo Back, Zongyou Jiang, Thuy An Pham, Seunga Choi, Hwa-Jung Kim

“…Notably, REA-immunized mice suppressed MTB growth to undetectable levels at 16 weeks post-infection, which was supported by gross and pathologic findings and acid-fast staining of the lung tissues, and maintained antigen-specific multifunctional IFN-γ+IL-2+TNF-α CD4+ T and long-lasting T cells producing cytokines in the tissues. …”
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Silence of NLRP3 Suppresses Atherosclerosis and Stabilizes Plaques in Apolipoprotein E-Deficient Mice by Fei Zheng, Shanshan Xing, Zushun Gong, Wei Mu, Qichong Xing

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Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice by Yizhuo Wang, Kunjian Liu, Zhiyong Qi, Tong Chen, Wei Yu, Yang Jiang, Guofeng Li, Huijie Xiao

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Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice by Elle EM Scheijen, Naomi Veeningen, Sam Duwé, Anna Ivanova, Jana Van Broeckhoven, Sven Hendrix, David M Wilson

“…Methods: Using a contusion model, a severe SCI was induced at the L1 spinal level in C57Bl/6J mice. The temporal and spatial presence of DNA damage was then determined via immunolabeling for the DNA damage marker, γH2AX, from 1 h post-injury (hpi) to 28 days post-injury (dpi). …”
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Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1 by Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan

“…The present study was carried out to investigate the effects and mechanisms of polydatin (PD) in septic mice. The model of cecal ligation and puncture (CLP-)induced sepsis was employed. …”
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