CULTURAL MORPHOLOGICAL AND BIOCHEMICAL CHARACTERISTICS OF BACILLUS SUBTILIS STRAINS by V. S. Rusaleyev, О. V. Pruntova, D. A. Vasilyev

“…Tested strains were nonpathogenic for white mice. Tests showed that spore biomass could be prepared both in liquid and on solid nutrient media. …”
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Silent Human Trypanosoma brucei gambiense Infections around the Old Gboko Sleeping Sickness Focus in Nigeria by Karshima Solomon Ngutor, Lawal A. Idris, Okubanjo Oluseyi Oluyinka

“…We isolated 7 (33.3%) trypanosomes from the 21 seropositive samples using immunosuppressed mice which were identified as T. b. gambiense group 1 by TgsGP-PCR. …”
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Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells by Mackenzie J. Dickson, I. Martin Sheldon, John J. Bromfield

“…The transcription factor CCAAT enhancer binding protein beta (CEBPβ) not only facilitates the transcription of LPS regulated cytokines, but also binds to the promoter region of CYP19A1 in humans, mice, and buffalo. We hypothesized that LPS alters CEBPβ signaling to reduce CYP19A1 expression, resulting in decreased estradiol secretion. …”
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Effect of Human Bone Marrow Mesenchymal Stem Cells on Burn Healing in Granulation Tissue Formation in Diabetic Rats by Gusti Revilla, Deddy Saputra, Dini Nurhasanah

“…Methods: This study was an experimental study with a post-test-only control group design, using 30 rats divided into two groups, the control group Phosphate Buffer Saline (PBS) and the treatment group (hBM-MSCs). Mice were induced by alloxan to cause hyperglycemia. …”
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Genetic Basis for Variation of Metalloproteinase-Associated Biochemical Activity in Venom of the Mojave Rattlesnake (Crotalus scutulatus scutulatus) by Ruben K. Dagda, Sardar Gasanov, Ysidro De La OIII, Eppie D. Rael, Carl S. Lieb

“…In addition, the venoms from the same rattlesnakes were tested for their ability to hydrolyze fibrinogen, fibrin, casein, and hide powder azure and for induction of hemorrhage in mice. Overall, based on genomic sequencing and biochemical data, we classified Mojave rattlesnake venom into four distinct groups of metalloproteinases. …”
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Development and Structural Variety of the Chondroitin Sulfate Proteoglycans-Contained Extracellular Matrix in the Mouse Brain by Noriko Horii-Hayashi, Takayo Sasagawa, Wataru Matsunaga, Mayumi Nishi

“…Here, we examined the starting period of PNN formation in male mice ranging in age from postnatal day 3 to week 11, mainly focusing on several cortical areas, limbic structures, hypothalamus, and brain stem, using lectin histochemistry with Wisteria floribunda agglutinin (WFA). …”
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Characterization of Coelenterazine Analogs for Measurements of Luciferase Activity in Live Cells and Living Animals by Hui Zhao, Timothy C. Doyle, Ronald J. Wong, Yuan Cao, David K. Stevenson, David Piwnica-Worms, Christopher H. Contag

“…In studies using living mice expressing Rluc in hepatocytes, administration of CLZN- e and -native produced the highest signal. …”
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The Role of Some Chemokines from the CXC Subfamily in a Mouse Model of Diabetic Neuropathy by Magdalena Zychowska, Ewelina Rojewska, Dominika Pilat, Joanna Mika

“…Using Antibody Array techniques, the increases in CXCL1 (KC), CXCL5 (LIX), CXCL9 (MIG), and CXCL12 (SDF-1) protein levels were detected in STZ-injected mice. No changes in CXCL11 (I-TAC) or CXCL13 (BLC) protein levels were observed. …”
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Hair Follicle Morphogenesis in the Treatment of Mouse Full-Thickness Skin Defects Using Composite Human Acellular Amniotic Membrane and Adipose Derived Mesenchymal Stem Cells by Wu Minjuan, Xiong Jun, Shao Shiyun, Xu Sha, Ni Haitao, Wang Yue, Ji Kaihong

“…In the present study, we observed the healing process of skin defects in nude mice and structural characteristics of the new skin after transplantation of isolated and cultured adipose derived mesenchymal stem cells (ADMSCs) onto the human acellular amniotic membrane (AAM). …”
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FOXG1 promotes osteogenesis of bone marrow-derived mesenchymal stem cells by activating autophagy through regulating USP14 by Yiqi Zhang, Long Zhou, Qin Fu, Ziyun Liu

“…Eight-week-old female C57BL/6J mice are used in OVX models, FOXG1 overexpression decreases bone loss by increasing bone formation. …”
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ABIN1 Inhibits Inflammation through Necroptosis-Dependent Pathway in Ulcerative Colitis by Jing Bao, Bin Ye, Yuhan Ren

“…Subsequently, the dextran sodium sulfate (DSS)-induced mice colitis model was used to verify the ABIN1 function in vivo. …”
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Sunitinib Reduced the Migration of Ectopic Endometrial Cells via p-VEGFR-PI3K-AKT-YBX1-Snail Signaling Pathway by Xiaodan Fan, Yanyan Tong, Yiting Chen, Yichen Chen

“…In addition to in vitro experiments, we also conducted in vivo experiments in mice. In the EMs mouse model, we found sunitinib reduced the number of heterotopic foci (t=11.16, ∗∗∗∗P<0.0001) and inhibited the expression of p-VEGFR, YBX1, and snail by immunofluorescence. …”
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Reprogramming of Mouse Calvarial Osteoblasts into Induced Pluripotent Stem Cells by Yinxiang Wang, Jessica Aijia Liu, Keith K. H. Leung, Mai Har Sham, Danny Chan, Kathryn S. E. Cheah, Martin Cheung

“…Here we adopted fluorescence-activated cell sorting-based strategy to isolate homogenous population of intramembranous calvarial osteoblasts from newborn transgenic mice carrying both Osx1-GFP::Cre and Oct4-EGFP transgenes. …”
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Whole-Body Physiologically Based Pharmacokinetic Modeling of GalNAc-Conjugated siRNAs by Emilie Langeskov Salim, Kim Kristensen, Erik Sjögren

“…<b>Methods</b>: Model development was performed using published studies in mice leveraging the PK-Sim^® standard implementation for large molecules with added implementations of ASGPR-mediated liver disposition and downstream target effects. …”
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Parabrachial CGRP neurons modulate active defensive behavior under a naturalistic threat by Gyeong Hee Pyeon, Hyewon Cho, Byung Min Chung, June-Seek Choi, Yong Sang Jo

“…To address this, we examined the role of CGRP neurons in active defensive behavior using a predator-like robot programmed to chase mice. Our electrophysiological results revealed that CGRP neurons encode the intensity of aversive stimuli through variations in firing durations and amplitudes. …”
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Investigation into the Effect of Aspartame on the Expression of p53 and BAX in Mouse Stomach Tissue by Angelique Cheryl, Aoife Mac Cooey

“…This study aims to examine how aspartame exposure affects p53 and BAX gene expression in normal mouse stomach tissue, shedding light on cellular stress and apoptosis mechanisms. Methods: Mice were sacrificed, and stomach tissue was excised and divided into control and treatment groups. …”
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Pharmacological Evaluation of Antidepressant-Like Effect of Genistein and Its Combination with Amitriptyline: An Acute and Chronic Study by Gaurav Gupta, Tay Jia Jia, Lim Yee Woon, Dinesh Kumar Chellappan, Mayuren Candasamy, Kamal Dua

“…The present study was designed to evaluate the acute and chronic antidepressant effect of genistein in combination with amitriptyline in mice. Animals were divided into six groups (n=6) for treatment with water, genistein, or amitriptyline, either alone or in combination for ten days. …”
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Molecular Basis of GABA Hypofunction in Adolescent Schizophrenia-Like Animals by Xiaodan Wang, Ying Hu, Wenxin Liu, Yuanyuan Ma, Xi Chen, Ting Xue, Donghong Cui

“…To address this issue, we transiently administrated MK-801 to mice on PND 10, which exhibited schizophrenia-relevant deficits in adolescence. …”
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Traditional Medicinal Herbs and Food Plants Have the Potential to Inhibit Key Carbohydrate Hydrolyzing Enzymes In Vitro and Reduce Postprandial Blood Glucose Peaks In Vivo by M. Fawzi Mahomoodally, A. Hussein Subratty, A. Gurib-Fakim, M. Iqbal Choudhary, S. Nahar Khan

“…In vivo studies on glycogen-loaded mice showed significant (P<0.05) depressive effect on elevation of postprandial blood glucose following ingestion of AM and MC extracts. …”
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Evaluation of Real-Life Investigational Use of Enoximone in Asthma, the Third Step in Drug Repurposing: A Preliminary Report by Jan Beute, Pieter Boermans, Alex KleinJan

“…The PDE3-inhibitor enoximone is a strong and quick bronchodilator and is known to successfully treat life-threatening bronchial asthma (status asthmaticus). Translational mice models showed anti-inflammatory effects when PDE3 was targeted. …”
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