Injectable iodine-containing peptide hydrogel for treatment of MRSA infection by Yu Zhang, Haiyan Liu, Weiqi Zhang, Yinghao Ding, Shengyi Zhang, Xiaowan Huang, Jiali Chen, Zhimou Yang, Feng Lin

“…Notably, I2@Nap-FFGP remarkably improved pregnancy rates in mice with endometritis owing to its therapeutic effects. …”
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CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension by Lea Strohm, Henning Ubbens, Dominika Mihalikova, Alexander Czarnowski, Paul Stamm, Michael Molitor, Stefanie Finger, Matthias Oelze, Dorothee Atzler, Philip Wenzel, Philipp Lurz, Thomas Münzel, Christian Weber, Esther Lutgens, Andreas Daiber, Steffen Daub

“…Hypertensive WT mice were also treated with a CD40-TRAF6 inhibitor (2.5 mg/kg/d, for 7d). …”
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Brown Adipose Tissue undergoes pathological perturbations and shapes C2C12 myoblast homeostasis in the SOD1-G93A mouse model of Amyotrophic Lateral Sclerosis by Marco Rosina, Silvia Scaricamazza, Flaminia Riggio, Gianmarco Fenili, Flavia Giannessi, Alessandro Matteocci, Valentina Nesci, Illari Salvatori, Daniela F. Angelini, Katia Aquilano, Valerio Chiurchiù, Daniele Lettieri Barbato, Nicola Biagio Mercuri, Cristiana Valle, Alberto Ferri

“…Furthermore, the BAT-derived EVs from SOD1-G93A mice displayed distinct changes in size distribution and cargo content. …”
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T Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Bone Loss via CD39 and CD73-Mediated ATP Hydrolysis by Yang X, Zhou Y, Zhou F, Bao L, Wang Z, Li Z, Ding F, Kuang H, Liu H, Tan S, Qiu X, Jing H, Liu S, Ma D

“…Inhibitors of CD39 and CD73, and an A2BR antagonist were used to explore the molecular mechanism of ApoEVs in promoting bone regeneration.Results: ApoEVs significantly reduced bone loss and promote the osteogenic differentiation of BMMSCs in ovariectomy (OVX) mice. We observed increased levels of extracellular ATP and a decrease in CD39 and CD73, key enzymes in ATP-to-adenosine conversion in bone marrow of OVX mice. …”
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Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption by Yue Xu, Xiuying Xiao, Chunxiao Ma, Ziyi Wang, Wenxin Feng, Hanyu Rao, Wei Zhang, Ningyuan Liu, Rebiguli Aji, Xiangjun Meng, Wei‐Qiang Gao, Li Li

“…Methods Colon tissues from IBD mice, SW620 cells and MC38 cells, were used as research subjects. …”
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Sodium butyrate restored TRESK current controlling neuronal hyperexcitability in a mouse model of oxaliplatin-induced peripheral neuropathic pain by Idy H.T. Ho, Yidan Zou, Kele Luo, Fenfen Qin, Yanjun Jiang, Qian Li, Tingting Jin, Xinyi Zhang, Huarong Chen, Likai Tan, Lin Zhang, Tony Gin, William K.K. Wu, Matthew T.V. Chan, Changyu Jiang, Xiaodong Liu

“…In vivo sodium butyrate supplementation restored oxaliplatin-induced Kcnj9 and Kcnk18 expression and pain-related behaviors in mice for at least 14 days. Oxaliplatin-induced increase in action potentials frequencies and decrease in magnitudes of KCNK18-related current were reversed in mice receiving sodium butyrate supplementation. …”
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Synthesis, Computational Studies and Preliminary Pharmacological Evaluation of New Arylpiperazines by Sushil Kumar, A. K. Wahi, Ranjit Singh

“…A series of novel arylpiperazines were synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced climbing behavior (D2 antagonism), 5-HTP induced head twitches (5-HT2A antagonism) and catalepsy studies in albino mice. The physicochemical similarity of the target compounds with respect to standard drugs clozapine, ketanserine and risperidone was assessed by calculating from a set of physiochemical properties using software programs. …”
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Managing Conflicts with Wildlife: Living with Snakes by Holly K. Ober, Steve A. Johnson, William M. Giuliano

“… Snakes provide many benefits to people and to the environment. They control rat and mice populations in the environment, for example, and in the laboratory, pygmy rattlesnake venom research helped develop medicine to thin the blood of heart attack patients. …”
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Neutrophil Reverse Migration Becomes Transparent with Zebrafish by Taylor W. Starnes, Anna Huttenlocher

“…In vivo imaging studies in zebrafish, and more recently in mice, have made the novel observation that neutrophils leave a site of inflammation through a process called neutrophil reverse migration. …”
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Exploiting Body and Place in Thomas Hardy’s Tess of the d’Urbervilles by Catherine Lanone

“…Her kinship with animals goes beyond mere metaphor to connect the plight of doomed birds, mice and snakes and of the vulnerable woman. Tess’s plight may be exceptional, but the exception is part of a wider meditation on instability and seasonal flux, as mutations tear the rural social fabric. …”
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SEGREGATION MODELS OF COMPLEX QUANTITATIVE TRAITS AND LINKAGE ANALYSIS IN EXTENDED RECOMBINANT INBRED CROSSES by M. S. Diakov, A. V. Osadchuk

“…The search procedure and linkage analysis have been tested with real data on cerebellum weight in laboratory mice as a quantitative trait. The developed software is briefly described.…”
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How does chronic pain lead to memory loss? by Suelen Pereira, Ivan Tomsic, Robson da Costa, Mychael V Lourenco

“…A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.…”
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Stochastic dynamics of SIRS epidemic models withrandom perturbation by Qingshan Yang, Xuerong Mao

“…The analytical results are all verified by computersimulations, including examples based on experiments in laboratorypopulations of mice.…”
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Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis by Nisha Goyal, Ram Prakash Tiwari, Geeta Shukla

“…By experimentation, it was found that the probiotic supplementation of either Lactobacillus casei, L. acidophilus, L. plantarum, or L. rhamnosus GG, 7 days prior to inoculation with G. lamblia trophozoites, reduced the rate of cyst excretion compared with Giardia-infected mice. Interestingly, L. GG was found to be the most effective probiotic in reducing the duration of giardia cycle and acts as an effective prophylactic probiotic for murine giardiasis but needs to be clinically correlated due to entirely different human microflora.…”
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Proinflammatory Effects of C-Peptide in Different Tissues by Dusica Vasic, Daniel Walcher

“…Several last findings demonstrated deposition of C-peptide in the vessel wall in ApoE-deficient mice and induction of local inflammation. Besides that, C-peptide has proliferative effects on human mesangial cells. …”
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Managing Conflicts with Wildlife: Living with Snakes by Holly K. Ober, Steve A. Johnson, William M. Giuliano

“… Snakes provide many benefits to people and to the environment. They control rat and mice populations in the environment, for example, and in the laboratory, pygmy rattlesnake venom research helped develop medicine to thin the blood of heart attack patients. …”
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Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation by Ai-Li Xu, Zheng Shen, Shi-Hao Wang, Hai-Yun Luan, Yong Xu, Ze-Chun Kang, Zi-Qi Liao, Jie Liu, Xiao-Lei Duan, Wei-Hua Bian, Hui Sun, Xin Xie

“…Therefore, this study aimed to investigate the role of ATG5 in DOX-induced cardiac toxicity. Mice were intravenously administered DOX (5 mg/kg) for 4 weeks to establish a cardiac toxicity model. …”
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Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation by Donghyun Kang, Jeeyeon Lee, Geunho Yook, Sehan Jeong, Jungkwon Shin, Mi-Sung Kim, Yi-Jun Kim, Hyeryeon Jung, Jinsung Ahn, Tae Woo Kim, Moon Jong Chang, Chong Bum Chang, Seung-Baik Kang, Won Ho Yang, Yong-ho Lee, Jin Won Cho, Eugene C. Yi, Chanhee Kang, Jin-Hong Kim

“…The topical deletion of Gata4 in this cartilage layer ameliorates post-traumatic osteoarthritis (OA) in mice while inhibiting O-GlcNAc transferase mitigates OA by decreasing GATA4 levels. …”
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Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models by Carol Milligan, Dale O. Cowley, William Stewart, Alyson M. Curry, Elizabeth Forbes, Brian Rector, Annette Hastie, Liang Liu, Gregory A. Hawkins

“…Given that the SOD1 transgenic mouse is one of the most highly studied and characterized models of ALS, we bred <i>SOD1^G93A</i> mice with IL6R trans-signaling mice to determine how enhanced trans-signaling influenced symptom onset and pathological processes, including neuromuscular junction (NMJ) denervation, glial activation and motoneuron (MN) survival. …”
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Invariant Natural Killer T Cells as Key Players in Host Resistance against Paracoccidioides brasiliensis by Joes Nogueira-Neto, Flavio V. Loures, Alessandra S. Schanoski, David A. G. Andrade, Michelangelo B. Gonzatti, Tania A. Costa, Bruno C. Vivanco, Patrícia Xander, Daniela S. Rosa, Vera L. G. Calich, Alexandre C. Keller

“…The deficient innate immune response of Jα18-/- mice to Pb18 infection resulted in increased fungal burden in the lungs and spleen. …”
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