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141
ErbB4 as a Potential Molecular Target in the Treatment of Esophageal Squamous Cell Cancers
Published 2014-01-01“…The main objective of this study was to examine whether miRNA-140-5p could target and control ErbB4 expression at transcriptional level. …”
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142
MicroRNA Expression Profiling in Behçet’s Disease
Published 2018-01-01“…Methods. miRNA microarray analysis was performed in blood cells of BD patients and healthy controls. miRNA expression profiles were analyzed using Affymetrix arrays with a comprehensive coverage of miRNA sequences. …”
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143
MicroRNAs in atrial fibrillation – have we discovered the Holy Grail or opened a Pandora’s box?
Published 2025-02-01“…Yet, the clinical relevance of miRNA evaluation and manipulation remains questionable. …”
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144
An Autocatalytic Platform Combining a Nonlinear Hybridization Chain Reaction and DNAzyme to Detect microRNA
Published 2024-12-01“…Conventional methods for miRNA detection, such as quantitative PCR and microarray analysis, often entail intricate sample preparation and lack the requisite sensitivity to detect low-abundance miRNAs like miRNA-21. …”
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145
Plant MicroRNA Prediction by Supervised Machine Learning Using C5.0 Decision Trees
Published 2012-01-01“…Some of the most critical features for training the predictor are the miRNA:miRNA∗ duplex energy and the number of mismatches in the duplex. …”
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146
Comprehensive profiling of serum microRNAs in normal and non-alcoholic fatty liver disease (NAFLD) patients
Published 2025-01-01“…The pathological mechanisms of NAFLD are linked to functional differences of miRNAs in different biological environments. The miRNA in serum exosomes may reflect the pathological state of the liver and changes in systemic metabolism, while the miRNA in serum may be associated with physiological processes other than the liver. …”
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147
Competing Endogenous RNA: The Key to Posttranscriptional Regulation
Published 2014-01-01“…Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA. …”
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148
miR-212 Promotes Cardiomyocyte Hypertrophy through Regulating Transcription Factor 7 Like 2
Published 2022-01-01“…In the successfully constructed rat model of abdominal aortic constriction and cardiomyocyte hypertrophy, ANP and myh7 were dramatically increased, myh6 expression was decreased, and miRNA-212 expression was increased. Overexpression of miRNA-212 in cardiomyocytes can promote cardiomyocyte hypertrophy, while knocking down miR-212 in cardiomyocytes can partially reverse cell hypertrophy. …”
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149
MicroRNA in Diabetic Nephropathy: Renin Angiotensin, AGE/RAGE, and Oxidative Stress Pathway
Published 2013-01-01“…Several reviews have covered aspects of miRNA function in biology and disease. Here, we review the role of miRNA in regulating the renin-angiotensin system, AGE/RAGE signalling, and under conditions of oxidative stress in the context of diabetic nephropathy.…”
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150
An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations
Published 2017-01-01“…Genetic polymorphisms in miRNA target sites may alter miRNA regulation and therefore result in the alterations of the drug targets. …”
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151
Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells
Published 2012-01-01“…To determine the relationship between miRNA sub-cellular distribution and cancer progression, we used microarray analysis to examine the miRNA expression levels in nucleus and cytoplasm of three human cell lines, one normal breast cell line and two breast cancer cell lines. …”
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152
MicroRNA functions in osteogenic differentiation of periodontal ligament stem cells: a scoping review
Published 2025-01-01“…This scoping review aimed to describe the differential microRNA (miRNA) functions in osteogenic differentiation of periodontal ligament stem cells (PDLSCs), and then analyze the potential of applying PDLSCs and miRNAs in bone regeneration. …”
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153
Noncoding RNA in the Regulation of Acute Aortic Dissection: From Profile to Mechanism
Published 2022-01-01“…Recently, research on acute aortic dissection has mainly focused on microRNA (miRNA). Studies have found that miRNA plays a critical regulatory role in the occurrence and development of acute aortic dissection. …”
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154
Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer.
Published 2021-01-01“…In this study, we analyzed the correlation between global miRNA and mRNA expression patterns derived from microarray profiling of 197 EOC patients to identify the signatures of miRNA-mRNA interactions associated with overall survival (OS). …”
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155
Identification of Aberrantly Expressed miRNAs in Gastric Cancer
Published 2014-01-01“…The noncoding components of the genome, including miRNA, can contribute to pathogenesis of gastric cancer. …”
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156
The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy
Published 2021-06-01“…Furthermore, GB-derived EVs have distinct miRNA contents and are able to penetrate the blood–brain barrier. …”
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157
Diagnostic Test to Identify Parkinson’s Disease from the Blood Sera of Chinese Population: A Cross-Sectional Study
Published 2022-01-01“…The isolated exosomes were characterized using CD63 detection and exosomal RNA was extracted. Serum miRNA profiling was carried out by synthesizing cDNA from the purified RNA and miRNA transcripts were determined by qRT-PCR using SYBR Green PremixScript. microRNA profiling strategy was employed for extracting the exosomal miRNAs from the exosomes. …”
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158
Discovery of Novel Leaf Rust Responsive microRNAs in Wheat and Prediction of Their Target Genes
Published 2014-01-01“…One wheat specific novel miRNA was identified but could not be ascribed or assigned to any known miRNA family. …”
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159
Inhibition of mmu_circ_0009303 improves metabolic dysfunction-associated steatotic liver disease by regulating lipid metabolism and oxidative stress
Published 2025-01-01“…Moreover, bioinformatics analyses revealed that miRNA-182-5p and Foxo3 are targets of mmu_circ_0009303 and miRNA-182-5p, respectively. …”
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160
Reciprocal regulation between DNMT3A/3B and microRNAs miRs-299-3p/-30e is a causal factor for the downregulation of microRNAs targeting androgen receptor in prostate cancer
Published 2025-02-01“…Background: Promoter hypermethylation is one of the events that downregulate microRNAs (miRNA), resulting in the differential expression of genes implicated in the progression of cancer. …”
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