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201
Identification of prognostic biomarkers of sepsis and construction of ceRNA regulatory networks
Published 2025-01-01“…A sepsis-related ceRNA networks, which consists of 4 circRNA, 26 miRNA, and 2 core gene, may guide mechanistic studies.…”
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202
miR124a-3p inhibitor alleviates AFB1-induced hepatoxicity via targeting chicken glucocorticoid receptor mRNA
Published 2025-03-01“…Glucocorticoid receptor (GR) plays crucial roles in various processes, including stress response, inflammatory response and toxin response, making it a therapeutic target for numerous diseases. microRNA (miRNA) can target and negatively regulate the expression of GR, thus interfering with its normal function. …”
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203
Stochastic modelling of PTEN regulation in brain tumors: A model for glioblastoma multiforme
Published 2015-05-01“…Starting from [23,24,25], we introduce a competitive stochastic model for post-transcriptional regulation of PTEN, including interactions with the miRNA and concurrent genes. Our model also covers protein formation and the backward mechanism going from the protein back to the miRNA.The numerical simulations show that the model reproduces the expected dynamics of normal glial cells. …”
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204
Association between the expression of specific microRNAs and prostate cancer progression- a systematic review and meta-analysis
Published 2025-02-01“…However, to improve our comprehension of MiRNA’s function in this condition, additional studies are required to address the limitations and investigate how MiRNA acts in many areas of PrCa.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42023428460.…”
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205
Elevated Circulating hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b in Type 2 Diabetes Mellitus with Diarrhea-Predominant Irritable Bowel Syndrome
Published 2016-01-01“…Although the differential expression of microRNA (miRNA) genes has been identified in many diseases, little information exists concerning the miRNA expression profile in type 2 diabetes mellitus (T2DM) with diarrhea-predominant irritable bowel syndrome (D-IBS). …”
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206
Reduced Presence of SARS-CoV-2 microRNA-like Small RNA in the Serum of Patients with Post-Acute Sequelae SARS-CoV-2 Infection
Published 2025-01-01“…This study examined the presence of SARS-CoV-2 microRNA (miRNA)-like small RNAs in extracellular fluids and their potential link to PASC by using a quantitative stem-loop RT-PCR MiRNA assay. …”
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207
MicroRNA Deregulation in Anaplastic Thyroid Cancer Biology
Published 2014-01-01“…In this review, we will explore the importance of miRNA deregulation for ATC cell biology.…”
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208
Treatment of Cancer Gene Changes in Chronic Myeloid Leukemia by Big Data Analysis Platform-Based Dasatinib
Published 2022-01-01“…Data were screened by miRNA–mRNA regulation template, and 20 differentially expressed mRNAs were obtained. …”
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209
Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts
Published 2016-07-01“…Moreover, we observed that this miRNA is also secreted by fibroblasts and in turn able to alter tumor cell behavior, by modulating its direct target E-cadherin, and NFs themselves. …”
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210
What Is in the Field for Genetics and Epigenetics of Diabetic Neuropathy: The Role of MicroRNAs
Published 2021-01-01“…Moreover, from a genetic perspective, it examined new findings of polymorphisms of miRNA genes in diabetic neuropathy. It considered in more depth the pathogenetic implications for diabetic neuropathy of the polymorphism of MIR499A and the related changes in the downstream action of miR-499a, showing how epigenetic and genetic studies may provide insight into pathogenetic mechanisms like mitochondrial dysfunction. …”
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211
miR-223 Inhibits the Polarization and Recruitment of Macrophages via NLRP3/IL-1β Pathway to Meliorate Neuropathic Pain
Published 2021-01-01“…Background. miRNA is an essential factor in neuropathic pain. …”
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212
Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes
Published 2018-01-01“…Hepatocyte-like cells (HLCs) obtained after differentiation resemble more fetal liver hepatocytes. MicroRNAs (miRNA) play an important role in the differentiation process. …”
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213
Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis
Published 2022-01-01“…Then, predict the key miRNA, qRT-PCR was used to verify the expression of miRNA in the peripheral blood and evaluated the correlation between them. …”
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214
MicroRNAs as Immunotherapy Targets for Treating Gastroenterological Cancers
Published 2018-01-01“…This review summarizes the current knowledge about the miRNAs and long noncoding RNAs that exhibit immunoregulatory roles in gastroenterological cancers and precancerous diseases of digestive system, as well as the miRNA-based clinical trials for gastroenterological cancers. …”
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215
miR-203 Expression in Exfoliated Cells of Tongue Coating Represents a Sensitive and Specific Biomarker of Gastroesophageal Reflux Disease
Published 2016-01-01“…The objective of this study was to investigate the miRNA expression of exfoliated cells of the tongue in patients with GERD versus healthy controls (Ctrls). …”
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216
Identification of Genetic Biomarkers for Diagnosis of Myocardial Infarction Compared with Angina Patients
Published 2020-01-01“…The miRNA-target pairs overlapped with hub genes were seen as key genes. …”
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217
Networking Salt Inducible Kinase 1 Regulatory Perturbations on Type 2 Diabetes- Breast Cancer Co-Morbidity Associated Molecular Bridge
Published 2025-01-01“…TF-miRNA regulatory network iteration was studied on Cytoscape, to identify SIK1 associated 143 PPIs. …”
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218
The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow
Published 2017-01-01“…The osteogenic differentiation capacity after miRNA treatment was assessed by ALP expression, ALP activity, and osteogenic marker gene expression. …”
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219
Exosomes and microRNAs as mediators of the exercise
Published 2025-01-01“…Environmental factors, such as physical exercise, can modulate miRNA expression and induce targeted changes in gene transcription. …”
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220
MicroRNA Profiling in Cartilage Ageing
Published 2017-01-01“…Osteoarthritis (OA) is the most common age-related joint disorder in man. MicroRNAs (miRNA), a class of small noncoding RNAs, are potential therapeutic targets for regulating molecular mechanisms in both disease and ageing. …”
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